Abstract：
:The existence of a so-called "vitauct process" is discussed by means of the glucocorticoid-induced stimulation of tyrosine aminotransferase activity. Own experiments show that the highest possible stimulation of the enzyme by cortisol and stress in the liver of old Wistar rats is not lower than in young-adult animals. After stress and 4 h after cortisol injection of 0.75 mg/100 g b.w. even a higher sensitivity seems to exist. A main problem for the interpretation of the results is the treatment of the control animals. Stress-free animals and animals to which the hormone-free solvent only under light ether narcosis was injected i.p. (stressed controls) were used. With the lowest injected hormone dose (0.25 mg cortisol/100 g b.w.) the results lie below those of the stressed controls. As a result of the findings of this paper, of the role of the enzyme, and of different influencing factors (e.g., glucocorticoid receptors) we suggest that the used model does not allow a conclusive decision about the existence of a vitauct process.
journal_name
Z Gerontol Geriatrjournal_title
Zeitschrift fur Gerontologie und Geriatrieauthors
Martin H,Benedix M,Dörfelt G,Martin Rsubject
Has Abstractpub_date
1996-07-01 00:00:00pages
295-301issue
4eissn
0948-6704issn
1435-1269journal_volume
29pub_type
杂志文章abstract：:During recent years, a discussion on work activity of retirees has commenced also in Germany. First, this contribution presents a survey of the North American phenomenon of bridge employment and, second, complements leadoff empirical results on individual motives and favored basic conditions in Germany. Individual and...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-009-0047-3
更新日期：2009-08-01 00:00:00
abstract：:The aging of the Italian population is an emerging public health priority. In 2025 Italy is expected to have the highest world median age with nearly half of the population over 50 years old. To avoid an unbearable burden of disease and disability on future generations, we must identify areas for intensive disease and...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910050139
更新日期：1999-12-01 00:00:00
abstract：BACKGROUND:Since the mid-1990s, supervised shared-housing arrangements (SHA; assisted living facilities) have developed as a specific type of small-scale living facility for elderly care-dependent persons with dementia in Germany, offering services different than those in residential care. Neither a uniform and binding...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-013-0524-6
更新日期：2014-11-01 00:00:00
abstract：:The incidence and prevalence of chronic renal disease (CKD) in elderly patients are continuously increasing worldwide. Loss of renal function is not only considered to be part of the aging process itself but also reflects the multimorbidity of many geriatric patients. Calculating the glomerular filtration rate using s...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-016-1109-y
更新日期：2016-08-01 00:00:00
abstract：:An enhanced inflammatory state - i.e. "inflammatory/pathogen burden" - in the elderly on the one hand results from physiological immunosenescence and on the other hand is modified by the individual immune history: the latter is determined by sequential infectious/pathogenic events ("multiple hits"). Immunosenescence m...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-007-0486-7
更新日期：2007-10-01 00:00:00
abstract：UNLABELLED:The main objective of the study was to examine the prevalence of problems and resources of an unselected cohort of nursing home residents. The sample includes residents (n=769) of an urban area in Southern Germany. The assessment definitions were used according to the Minimum Data Set of the Resident Assessm...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-003-0097-x
更新日期：2003-08-01 00:00:00
abstract：:Three strategies are followed in handling the key issue within the field of action of care an services for the elderly: securing the material needs of those requiring care, creating appropriate care structures, and providing an effective counselling back-up to alleviate interface problems. Those latter, process-orient...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s003910050055
更新日期：1998-10-01 00:00:00
abstract：:Depression in later life unfavorably impacts on the prognosis of comorbid somatic medical conditions. There are mutually reciprocal risk relationships with several frequently occurring medical conditions, such as diabetes, ischemic heart disease, stroke and Parkinson's disease. A wide range of psychological and psycho...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-016-1022-4
更新日期：2016-07-01 00:00:00
abstract：:For a period of 3 consecutive years, all fall events were prospectively recorded in geriatric hospital in-patients by using a standardized protocol. The incidence was 9.1 fall events/1000 hospital days in 5946 patients, and 41.0/1000 hospital days in 1015 patients (17.0%) who actually had falls. The fall rate varied b...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-004-0204-7
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVE:This study aimed to investigate the effect exerted by teriparatide on the repair of femoral metaphyseal defect in ovariectomized rats. METHOD:Female Sprague-Dawley rats were ovariectomized and after 3 months a critically sized defect of 3 mm in diameter-a through-hole bone defect-was drilled into each distal...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-015-0949-1
更新日期：2016-07-01 00:00:00
abstract：:As part of a research project, a behavior therapy-oriented cognitive training program, designed to improve the cognitive ability of middle-aged employees (50 to 59 years), was implemented and evaluated. The goal of the training program was to analyze the cognitive, affective and behavior-related conditions of memory d...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-009-0044-6
更新日期：2009-12-01 00:00:00
abstract：:The NaCl content of the culture medium of human fibroblasts (WI-38) was elevated from 0.12 M to 0.23 M. Previously it had been shown that exposure of fibroblasts to such high NaCl conditions resulted in a rise of both glycolysis and respiration ("energetic stress"), mainly due to increased demands of energy for active...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910170014
更新日期：2001-12-01 00:00:00
abstract：:The number of accidents caused by older car drivers increases annually in Germany. Typical errors of older drivers concern the right of way, changes of direction and conflicts with pedestrians at cross walks. These errors are attributed to deficient information gathering and processing caused by old age and illness. I...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910050123
更新日期：1999-10-01 00:00:00
abstract：:The age appropriateness of a pharmaceutical product for older patient populations is most important in achieving ease of use, administration, and adherence as well as the therapeutic benefit of the drug. Drug development is a lengthy and risky investment accompanied by extensive regulatory requirements to meet all the...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-012-0361-z
更新日期：2012-08-01 00:00:00
abstract：:Scabies is a frequent ectoparasitosis the prevalence of which also seems to increase in older patients. Correct and timely diagnosis of scabies in older age is hampered by atypical clinical manifestations, the potential lack of pruritus and a variety of differential diagnoses. Scabies crustosa, a highly contagious sub...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-019-01650-z
更新日期：2019-12-01 00:00:00
abstract：:Malignant wounds arise either primary or secondary in the context of a malignant transformation of already existing wounds. A plethora of skin tumors, such as basal cell carcinoma, squamous cell carcinoma, melanoma, lymphoma as well as cutaneous metastases of other malignancies can ulcerate and be the cause of maligna...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-019-01629-w
更新日期：2020-10-01 00:00:00
abstract：:The degree of Objective Health Burden (OHB) is an expert assessment of the impairment caused by somatic illnesses. It allows an overall clinical rating of the severity of a patient's somatic condition, considering all available information, not only the content or number of diagnoses. The rating on a five point scale ...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910050111
更新日期：1999-08-01 00:00:00
abstract：:The present investigation aimed to assess the health-related QoL (HRQoL) of elderly people living in two settings: (i) rural community and (ii) homes for the elderly in a district of South India. The data are drawn from elderly (>60 years of age) sampled from both settings. The short form 36-item health survey (SF-36)...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-009-0077-x
更新日期：2010-08-01 00:00:00
abstract：:The prevalence of chronic pain increases with age. The awareness of pain in geriatric patients is more difficult than in younger people because of various reasons. The occupational groups of the geriatric team might be different in respect of discerning symptoms of pain. 126 geriatric patients were enrolled in this st...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910170039
更新日期：2001-10-01 00:00:00
abstract：:The mortality in elderly patients over the age of 80 years with peptic ulcers in the case of complications, such as bleeding and perforation is higher than in the general population. Duodenal ulcers are associated with Helicobacter pylori infections in 90% of cases and in 70% of gastric ulcers. The treatment of elderl...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-017-1190-x
更新日期：2017-02-01 00:00:00
abstract：:Older patients clearly benefit from a kidney transplantation despite multiple comorbidities and complications, particularly with respect to life expectancy. Older patients remaining on dialysis on average die earlier compared to patients who underwent a kidney transplantation. In addition, patients experience a signif...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-016-1118-x
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Research on nonformal education often focuses on participation within employment. Participation of workers decreases with age; however, recent studies show an increase in participation in nonformal education of older workers. It remains, however, unclear if this trend spills over to retirement. OBJECTIVE:In...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-017-1247-x
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Little is known about the prevalence of falls and the related risk factors in the general population of community-living older people in Germany. OBJECTIVES:To assess the prevalence and related predictors of different types of falls in a sample of community-dwelling 65 years and older people in Germany livi...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-008-0506-2
更新日期：2009-02-01 00:00:00
abstract：AIM OF THE STUDY:Analysis of differences between oncologic and non-oncologic patients in the first German hospital-based special care unit for palliative geriatrics. METHODS:Systematic analysis of patients' records according to a standardized protocol. RESULTS:A total of 217 patients from a hospital-based special car...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-010-0148-z
更新日期：2010-12-01 00:00:00
abstract：:Because of age-related modifications of the heart, lung, and circulation, several cardiopulmonary parameters present altered normal and reference values with increasing age. Other parameters, for example, arterial blood pressure, change only insignificantly with age. In older age groups it is more difficult to establi...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：
更新日期：1997-05-01 00:00:00
abstract：:The HILDE project proceeds from a theoretical conception of quality of life which considers both the significance of objective living conditions claimed in the Swedish level of living approach and the significance of processes of subjective perceptions and judgements accentuated in the American quality of life approac...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-006-0408-0
更新日期：2006-10-01 00:00:00
abstract：:Geriatric patients with non-valvular atrial fibrillation (AF) are increasingly being treated with novel oral anticoagulants (NOAC) to prevent ischemic stroke. This article highlights the outcome of an expert meeting on the practical use of NOAC in elderly patients. An interdisciplinary group of experts discussed the c...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-016-1027-z
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:Which deficits in cognitive performance indicate the onset of a pathological deterioration process in older persons? AIM AND OBJECTIVES:Based on an established dementia screening test in elderly adults, a differentiation can be made between healthy cognitive performance and the onset of pathological deficit...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-017-1263-x
更新日期：2018-04-01 00:00:00
abstract：:Sufficient denture hygiene is very important in particular for immunocompromised and bedridden patients to reduce the risk posed by the aspiration of pathogenic microorganisms. In addition to mechanical cleansing, chemical denture cleansers are suitable for daily use at home. However, they continue to be seen as probl...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-010-0153-2
更新日期：2011-06-01 00:00:00
abstract：:Depression in old age is common and also dangerous due to somatic comorbidity and suicide; however, it is often not recognized and not adequately treated. Psychotherapy is almost never offered to the elderly. However, clinical experience, single-case studies and some controlled trials show effectiveness--at least to t...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-012-0469-1
更新日期：2013-02-01 00:00:00
