Abstract:
OBJECTIVE:To report eight cases of sensory Guillain-Barré syndrome (GBS). BACKGROUND:The concept of sensory equivalent to ascending paralysis of GBS was raised in 1958, and the diagnostic criteria for a sensory loss and areflexia variant of GBS were proposed in 1981. However, clinical cases meeting these criteria have been relatively scarce. METHODS:During a 13-year period between 1986 and 1999, the authors collected eight cases of an acute sensory demyelinating neuropathy that met most of the proposed diagnostic criteria of a sensory variant of GBS. RESULTS:In all patients, sensory neuropathy was sudden at onset and peaked to maximal deficit within 4 weeks. In five (63%) cases, there was an antecedent viral illness. All patients had objective sensory loss and diminished or absent reflexes. None showed any muscle weakness. In all four patients in whom the spinal fluid was examined during the first 4 weeks, there was albuminocytologic dissociation. All of the patients had electrophysiologic evidence of demyelination in at least two nerves. Demyelination was demonstrated in motor nerve conduction in seven patients and in sensory nerve conduction in one, indicating that motor nerve conduction studies were the key for the diagnosis of demyelinating neuropathy. All patients had sensory nerve conduction abnormalities in at least one nerve. Three patients responded to immunotherapies. All had a favorable outcome, with a monophasic course of disease and no sign of relapse. CONCLUSION:The current study confirms the existence of sensory GBS.
journal_name
Neurologyjournal_title
Neurologyauthors
Oh SJ,LaGanke C,Claussen GCdoi
10.1212/wnl.56.1.82subject
Has Abstractpub_date
2001-01-09 00:00:00pages
82-6issue
1eissn
0028-3878issn
1526-632Xjournal_volume
56pub_type
杂志文章,评审相关文献
NEUROLOGY文献大全abstract::Two cases of giant-cell arteritis with cerebral arteritis are presented. The clinical situation and the suggestive but nonspecific angiographic features make the antemortem diagnosis possible. Greater awareness of this entity will facilitate its diagnosis and the institution of effective steroid therapy. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.27.8.794
更新日期:1977-08-01 00:00:00
abstract::This review summarizes evidence, primarily from recent human studies, indirectly supporting a novel hypothesis: that the assessment of healthy individuals' responses to standardized noxious stimuli in a controlled laboratory environment has important implications for the later risk of developing a broad spectrum of ch...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/01.wnl.0000171862.17301.84
更新日期:2005-08-09 00:00:00
abstract::We studied a 55-year-old woman with macrosquare wave jerks and macrosaccadic oscillations with a vertical component. The oscillations almost completely disappeared after administration of diazepam, clonazepam, thiamylal, or phenobarbital. A disorder of GABAergic tonic inhibitory system from the substantia nigra to sup...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.9.1230
更新日期:1986-09-01 00:00:00
abstract::The local cerebral metabolic rate for glucose (1=CMRg) was computed in rats with methylphenidate-induced stereotypy using the quantitative 14C-2-deoxyglucose (2-DG) technique. Four rats received methylphenidate 15 mg per kilogram IP. Compared to five control animals, treated rats showed statistically significant (p le...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.32.4.377
更新日期:1982-04-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that extratemporal neuronal networks are involved in dystonic posturing (DP) observed in mesial temporal epilepsy (MTLE). METHODS:The authors analyzed electroclinical findings in 36 patients with MTLE with or without DP. Three DP types were defined (types I, II, III) corresponding to a...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000184510.44808.50
更新日期:2005-11-22 00:00:00
abstract::Mutations in DJ-1 are a cause of autosomal recessive parkinsonism. Polymorphism of genes implicated in hereditary forms of parkinsonism may be a predisposing factor in sporadic Parkinson's disease (PD). The authors analyzed whether a polymorphism (g.168_185del) within exon 1 of DJ-1 contributes to the risk of sporadic...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000083992.28066.7e
更新日期:2003-10-14 00:00:00
abstract:BACKGROUND:Frontotemporal dementia (FTD) is currently distinguished from AD primarily on the basis of behavioral features because studies of cognition have shown negligible or inconsistent differences. However, the poor discriminability of cognitive measures may relate to reliance on imprecise clinically diagnosed grou...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.58.12.1801
更新日期:2002-06-25 00:00:00
abstract:OBJECTIVE:To describe and evaluate the incidence and risk factors of severe neurologic events (SNE) in pediatric recipients of allogeneic or autologous hematopoietic stem cell transplantation (HSCT) for hematologic or nonhematologic diseases. METHODS:Retrospective analysis of 272 consecutive children admitted to the G...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000036608.42104.b9
更新日期:2002-12-24 00:00:00
abstract::Since the emergence of the specialty, neurologists have worked with a rather restricted list of relatively inexpensive pharmacologic agents. This is rapidly changing with the development of new agents for the treatment of migraine, multiple sclerosis, Parkinson's disease, Alzheimer's disease, and epilepsy, accelerated...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.45.3.569
更新日期:1995-03-01 00:00:00
abstract::A rare case of solitary CNS chloroma in a patient with chronic granulocytic leukemia (CGL) is described. This appears to be the first reported case of intracranial chloroma in CGL without systemic blastic crisis. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.33.8.1089
更新日期:1983-08-01 00:00:00
abstract::A 20-year-old woman using an oral diet aid preparation containing phenylpropanolamine presented with an intracerebral hemorrhage and angiographic evidence of cerebral vasculitis. Gas chromatography demonstrated phenylpropanolamine in the urine. Even when used within recommended guidelines, phenylpropanolamine usage sh...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.35.3.405
更新日期:1985-03-01 00:00:00
abstract::In a cohort of 337 patients with subarachnoid hemorrhage (SAH), we investigated the relationship between blood glucose levels, baseline characteristics, and outcome by means of Student's t-test and multivariate logistic regression. The mean glucose levels on admission and from day 1 to 10 were significantly higher in ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000090466.68866.02
更新日期:2003-10-28 00:00:00
abstract:OBJECTIVE:To determine whether physical activity and body mass index (BMI) predict instrumental or basic activities of daily living (I/ADL) trajectories before or after stroke compared to individuals who remained stroke-free. METHODS:Using a prospective cohort, the Health and Retirement Study, we followed adults witho...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000003888
更新日期:2017-05-02 00:00:00
abstract:OBJECTIVE:Cell-based therapies are being investigated as an adjunct to IV thrombolysis or mechanical thrombectomy in ischemic stroke. This review summarizes the potential applications as well as challenges of intravascular cell delivery in ischemic stroke. METHOD:We conducted a search of Medline as well as the clinica...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0b013e31826959d2
更新日期:2012-09-25 00:00:00
abstract:OBJECTIVE:To assess the recovery process in patients after an acute optic neuritis (ON) attack, comparing static and dynamic visual functions. METHODS:In this prospective controlled study, 21 patients with unilateral, first-ever ON were followed over the course of 1 year. Standard visual tests, visual evoked potential...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31821f4602
更新日期:2011-06-14 00:00:00
abstract:OBJECTIVE:To further investigate the basis of abnormal neuromuscular transmission in two patients with congenital myasthenic syndrome associated with episodic ataxia type 2 (EA2) using stimulated single fiber EMG (SFEMG) and in vitro microelectrode studies. METHODS:Two patients with genetically characterized EA2 previ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000099748.41130.9a
更新日期:2003-12-23 00:00:00
abstract::Tizanidine, an imidazoline that acts as an agonist at alpha 2-adrenergic receptors, has been shown to be effective in reducing spasticity caused by MS. This multicenter study (14 sites) assessed the efficacy and safety of oral tizanidine in patients who had spinal cord injury of > 12 months' duration. Of the 124 patie...
journal_title:Neurology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1994-11-01 00:00:00
abstract:OBJECTIVE:To assess the frequency of this finding in patients with minor stroke and TIAs compared to those with stroke mimics and to evaluate the level of agreement between examiners to detect an upgoing thumb sign. METHODS:We previously reported an upgoing thumb sign as a subtle clinical finding in patients with tran...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000004157
更新日期:2017-07-25 00:00:00
abstract::The triad of normal-pressure hydrocephalus, parkinsonism, and primary empty sella appeared in a 70-year-old woman. There was dramatic resolution of the extrapyramidal signs and symptoms on treatment with levodopa-carbidopa and ventriculojugular shunt. The syndrome may be the result of several mechanisms, but an altera...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.28.11.1191
更新日期:1978-11-01 00:00:00
abstract::Human cytomegalovirus and herpes simplex virus DNA probes were labeled in vitro and hybridized to the DNA extracted from brains of patients with multiple sclerosis (MS) to detect the presence of genetic information related to these viruses. We were unable to detect any virus-related genetic information complementary t...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.30.5.530
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVE:To define the natural history of the C9orf72 amyotrophic lateral sclerosis (C9ALS) patient population, develop disease biomarkers, and characterize patient pathologies. METHODS:We prospectively collected clinical and demographic data from 116 symptomatic C9ALS and 12 non-amyotrophic lateral sclerosis (ALS) f...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000008359
更新日期:2019-10-22 00:00:00
abstract::The authors identified two novel heterozygous missense transitions in the gene for the mitochondrial polymerase gammaA subunit (POLG) in a family with an autosomal recessive syndrome comprising progressive external ophthalmoplegia (PEO), polyneuropathy, ataxia, sensorineural hearing loss, and affective disorders. Thes...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.62.2.316
更新日期:2004-01-27 00:00:00
abstract:BACKGROUND:The annual relapse rate has been commonly used as a primary efficacy endpoint in phase III multiple sclerosis (MS) clinical trials. The aim of this study was to determine the relative contribution of different possible prognostic factors available at baseline to the on-study relapse rate in MS. METHODS:A to...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000187122.71735.1f
更新日期:2005-12-13 00:00:00
abstract:OBJECTIVE:The natural history of succinic semialdehyde dehydrogenase (SSADH) deficiency in adulthood is unknown; we elucidate the clinical manifestations of the disease later in life. METHODS:A 63-year-old man with long-standing intellectual disability was diagnosed with SSADH deficiency following hospitalization for ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000001906
更新日期:2015-09-08 00:00:00
abstract::We reviewed the records of all patients with optic neuritis (ON) in Olmsted County, Minnesota, identified through the comprehensive records-linkage system at the Mayo Clinic, and identified 156 ON patients from 1935 to 1991 who had onset of the disease while residing in Olmsted County (incidence cases). Poisson regres...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.45.2.244
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:To incorporate standardized documentation into an epilepsy clinic and to use these standardized data to compare patients' perception of epilepsy diagnosis to provider documentation. METHODS:Using quality improvement methodology, we implemented interventions to increase documentation of epilepsy diagnosis, se...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000009778
更新日期:2020-07-14 00:00:00
abstract:OBJECTIVE:To validate the Narcolepsy Severity Scale (NSS), a brief clinical instrument to evaluate the severity and consequences of symptoms in patients with narcolepsy type 1 (NT1). METHODS:A 15-item scale to assess the frequency and severity of excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, slee...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000003787
更新日期:2017-04-04 00:00:00
abstract::We report of a woman aged 52 years born to consanguineous parents and seeking treatment for progressive dementia and delusion. Neurologic examination revealed dementia and emotional instability, indifference, and confabulation. There was also mild spasticity of the bilateral lower limbs. MRI revealed diffuse white mat...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000123117.11264.0e
更新日期:2004-05-11 00:00:00
abstract:OBJECTIVE:To define a clinical syndrome associated with active drug abuse in HIV-infected individuals. METHODS:We performed a retrospective review to identify individuals treated at the Johns Hopkins Hospital from 1993 to 2008 who were HIV-infected and were actively abusing drugs and had bilateral basal ganglia lesion...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31820e7b4e
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To characterize the clinical course of pathologically diagnosed hippocampal sclerosis dementia (HSD). BACKGROUND:Dementia associated with HSD is incompletely characterized. Previous studies suggest similarities to both Alzheimer disease (AD) and frontotemporal dementia (FTD). METHODS:Case-control analysis o...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000133008.89613.82
更新日期:2004-08-10 00:00:00