Human fibroblasts produce "pregnancy-specific" beta-1 glycoprotein in vitro.

Abstract:

:Normal and genetic variant strains of nonmalignant human fibroblasts produce in vitro a substance indistinguishable from the recently described "pregnancy-specific" beta-1 glycoprotein (PSbetaG, PAPP-C, SP1). Demonstration of this presumed placenta-specific material in a nonplacental site raises questions about its normal physiologic role and use as a cancer marker.

journal_name

Am J Obstet Gynecol

authors

Rosen SW,Kaminska J,Calvert IS,Aaronson SA

doi

10.1016/0002-9378(79)90938-4

subject

Has Abstract

pub_date

1979-08-01 00:00:00

pages

734-8

issue

7

eissn

0002-9378

issn

1097-6868

pii

0002-9378(79)90938-4

journal_volume

134

pub_type

杂志文章
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