Abstract:
:The sera from patients with prostatic cancer have been observed to posses an unidentified factor capable of inhibiting the migration of leukocytes and the proliferative response to the nonspecific mitogen, phytohemagglutinin. Observation of inhibition of these two suggested in vitro correlates fo cell-mediated immunologic responsiveness emphasizes (1) the importance to the adjunctive diagnosis and prognosis of patients with malignancy of identifying the presence of abnormal serum proteins, and (2) the role of humoral inhibitory or "immunoregulatory" factors as potential abrogators of mechanisms of host resistance, for example, immunologic surveillance, and thus the degree to whcih the host may respond to his tumor.
journal_name
Urologyjournal_title
Urologyauthors
Ablin RJ,Guinan PD,Bruns GR,Sadoughi N,Bush IMdoi
10.1016/0090-4295(75)90586-5subject
Has Abstractpub_date
1975-07-01 00:00:00pages
22-9issue
1eissn
0090-4295issn
1527-9995journal_volume
6pub_type
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