Abstract:
:This randomized study compared the fibrinolytic circadian rhythm of healthy older men and older women (average age 66 +/- 5), before and after 6 months of endurance training versus stretching controls. Compared with men, women at baseline had similar rhythms for tissue plasminogen activator (t-PA) activity and plasminogen activator inhibitor 1 (PAI-1) activity, but lower levels of total t-PA antigen. In men (N = 16), endurance training increased VO2max 15% (P < 0.001), while decreasing PAI-1 activity 37% (P = 0.034) and total t-PA antigen 18% (P = 0.0003) between midnight and 6 a.m., but did not affect t-PA activity. In women (N = 9), endurance training increased VO2max 18% (P = 0.003), and increased t-PA activity 20% (P = 0.027) and total t-PA antigen 55% (P = 0.007) between 10 p.m. and 4 a.m., but had no effect on PAI-1 activity. After endurance training there were no significant differences in the fibrinolytic circadian rhythm of men versus women. Six months of nonaerobic stretching had no effect on VO2max or fibrinolysis in men (N = 11) or women (N = 8). This study indicates that potentially favorable changes occur in fibrinolytic factors after endurance training in older men and older women.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Chandler WL,Schwartz RS,Stratton JR,Vitiello MVdoi
10.1097/00005768-199606000-00001subject
Has Abstractpub_date
1996-06-01 00:00:00pages
647-55issue
6eissn
0195-9131issn
1530-0315journal_volume
28pub_type
临床试验,杂志文章,随机对照试验abstract:PURPOSE:This study aims to examine whether muscle glycogen availability is associated with fatigue in a repeated exercise bout following short-term recovery. METHODS:Ten endurance-trained individuals underwent two trials in a repeated-measures experimental design, each involving an initial run to exhaustion at 70% of ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000737
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate the influence of mouth rinsing a CHO-electrolyte (CHO-E) solution on 1-h running performance. A second study determined whether mouth rinsing a CHO-E solution altered the blood glucose and plasma insulin concentrations at rest. METHODS:After a 13-h fast, 10 endurance-tr...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/MSS.0b013e3181bac6e4
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:This study tested the hypothesis that the magnitude of cardiovascular (CV) drift and decrease in maximal oxygen uptake (V[spacing dot above]O2max) would be greater at 35 degrees C than at 22 degrees C. METHODS:The increase in HR and decrease in stroke volume (SV) between 15 and 45 min of cycling at 59.2 +/- 1....
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181666ed7
更新日期:2008-06-01 00:00:00
abstract::The case of a table tennis player suffering from intra-articular loose bodies of the elbow is reported. The patient developed the first signs of osteochondritis dissecans of the right lateral humeral condyle at age 16 but underwent surgery only 6 yr later. He has now resumed training and competition, despite some resi...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-08-01 00:00:00
abstract:PURPOSE:To determine substrate utilization and energy expenditure during maximal and submaximal exercise and recovery in adolescents with cystic fibrosis (CF) and healthy age-matched controls (C). METHODS:Ten clinically stable CF patients (four girls, six boys; age = 10-22 yr) were matched by body mass index, age, gen...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318188449b
更新日期:2009-02-01 00:00:00
abstract:UNLABELLED:Clinical treatment in physical rehabilitation routinely uses perceived relative forces. PURPOSE:This study used psychophysical methods to quantify subjects' errors during submaximal muscular force production. METHODS:A sample of young adult (aged 23 +/- 3 yr) females (N = 60, 62 +/- 14 kg) and males (N = 5...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200002000-00028
更新日期:2000-02-01 00:00:00
abstract::We sought to determine how a stationary activity such as playing a stringed instrument may affect energy expenditure (EE) in adolescents. Using automated indirect calorimetry, we measured EE in eight adolescents (1 male, 7 females, 14.2 +/- 2.1 yr) while they each performed the following activities: watching televisio...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract::This article focuses on sports related spinal cord and nerve injuries, ranging from mild "stinger" syndrome to complete quadriplegia. Particular emphasis is placed on recommendations for return to competition after such injuries. Cervical spinal cord symptoms after a spine injury from contact sports require a more pre...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199707001-00005
更新日期:1997-07-01 00:00:00
abstract::Fatigue can be defined as the failure to maintain an expected power output. This is often an antecedent to some sports-related injury. It is important for those involved in physical performance to be familiar with the variety of mechanisms which can lead to fatigue. All too often, a single factor is described as the c...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1990-08-01 00:00:00
abstract::Although onset and maximal claudication pain are attained sooner as exercise intensity is increased, it is unclear whether dissipation of pain during recovery is altered. Thus, this study examined whether walking at gradually higher intensity would prolong the time needed for claudication pain to dissipate during reco...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1993-08-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the effect of acute ingestion of modafinil (M) on time to exhaustion during high-intensity exercise. Modafinil (M) is a psychostimulant developed to treat narcolepsy, with "arousal" properties attributed to an increased release of dopamine in the CNS. Because other s...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/01.mss.0000128146.12004.4f
更新日期:2004-06-01 00:00:00
abstract::A biomechanical model of the ankle joint was developed and was used to predict the forces at the ankle during the stance phase of running. Measurements from five cadavers were averaged to obtain insertion points and directions of pull of equivalent tendons with respect to the assumed center of the ankle joint. A minim...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198204000-00010
更新日期:1982-01-01 00:00:00
abstract::The purpose of this study was to assess the relationship between the isometric and isokinetic peak torque (PT) (speed of movement 0, 60, and 180 degrees.s-1) and the peak torque acceleration energy (PTAE) and average power (AP) of multiple contractions (180 degrees.s-1) of the quadriceps and hamstrings in 38 patients ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract::A group of 103 female weight lifters (WL) and 92 control (C) women answered a survey concerning eating behavior and attitudes (including the Eating Disorder Inventory) and menstrual function. The incidence of menstrual dysfunction, defined as oligomenorrhea plus amenorrhea, was significantly higher for the WL (30%) th...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::The downswing phase in golf was represented as a double pendulum pivoted at the shoulder joint and hinged at the wrist. The motion of such a pendulum was used to derive a series of equations which were used to describe the instantaneous values of several of the component features of the downswing. Results of this anal...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198201000-00012
更新日期:1982-01-01 00:00:00
abstract:PURPOSE:To examine whether normalized quadriceps and hamstring strength would predict quadriceps and hamstring muscle activation amplitudes and whether these neuromuscular factors would predict knee kinematics and kinetics during a drop jump task. METHODS:Thirty-nine females and 39 males were measured for isometric qu...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181e3b3f
更新日期:2009-04-01 00:00:00
abstract:PURPOSE:The reliability of athletes to recall and self-report a concussion history has never been quantified. This study examined the reliability of the self-report concussion history measure and explored determinants of recall in the number of self-reported concussions in a group of retired professional football playe...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31823240f2
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION:Physical endurance can be limited by muscle glycogen stores, in that glycogen depletion markedly reduces external work. During carbohydrate restriction, the liver synthesizes the ketone bodies, D-β-hydroxybutyrate, and acetoacetate from fatty acids. In animals and in the presence of glucose, D-β-hydroxybut...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000001292
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine the impact of exercise-induced metabolic stress on hormonal responses and chronic muscular adaptations. METHODS:We compared the acute and long-term effects of an "NR regimen" (no-rest regimen) and those of a "WR regimen" (regimen with rest period within a set). Twenty-s...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract::Many experimental studies have utilized the activity of dopamine-beta-hydroxylase (DBH) as an index of sympathetic activity, since this enzyme is not submitted to uptake mechanisms or to enzymatic metabolism as are the circulating catecholamines norepinephrine (NE) and epinephrine (E). However, large discrepancies hav...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198512000-00011
更新日期:1985-12-01 00:00:00
abstract:PURPOSE:Heart transplant recipients (HTx) have a high prevalence of hypertension. Although exercise training promotes blood pressure (BP) reduction in HTx, the effects of a single exercise bout are unknown. Thus, we analyzed the acute effects of heated water-based exercise (HEx) versus land-based exercise (LEx) on ambu...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000846
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine the effect of thermal stress and hydration status on immune function during exercise. METHODS:Ten trained men completed four cycle ergometer rides at 55% VO2peak under the following conditions: EN (euhydrated neutral; 22 degrees C, 30% RH), DN (dehydrated neutral), EH...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200212000-00013
更新日期:2002-12-01 00:00:00
abstract::The purpose of this experiment was to determine whether reflexive, or more broadly, automatic hamstrings excitation could be elicited during isometric, maximum effort, step increases in knee extension torque. Eight healthy subjects without lower extremity dysfunction or injury performed maximum effort isometric knee e...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract:PURPOSE:Traction-induced injury, related to muscles of the superficial and deep posterior compartments, has been implicated as the cause of medial tibial stress syndrome (MTSS) with symptoms commonly occurring in the distal third of the posteromedial tibia. Standard anatomic texts do not identify this region as an atta...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181a6519c
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:Few epidemiological studies have been conducted among middle-aged women on long-term total and specific physical activity (PA) trends. We studied in a cross-sectional setting the relationship of self-reported total daily PA with age and calendar time. METHODS:In a population-based cohort of 38,988 women aged 4...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000185086.19220.b3
更新日期:2006-02-01 00:00:00
abstract:PURPOSE:To examine the influence of two patellofemoral braces on pain response, patellar alignment, and patellofemoral joint contact area in persons with patellofemoral pain. METHODS:Fifteen women between the ages of 18 and 45 yr with a diagnosis of patellofemoral pain participated. After the assessment of pain respon...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000132376.50984.27
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:We evaluated the impact of anthracyclines on left ventricular function and myocardial tissue characteristics using cardiovascular magnetic resonance (CMR) imaging to determine their relationship with V˙O2peak. METHODS:Women with breast cancer who had not yet received treatment (No-AT, n = 16) and had received ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002469
更新日期:2021-02-01 00:00:00
abstract:PURPOSE:The present longitudinal study assessed cardiorespiratory capacity and running economy of Olympic athletes over several decades to measure changes in fitness in an elite group during aging. METHODS:Twenty-six male runners training for the 1968 Olympics were recruited. HR, V˙O2max, ventilation, and running econ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001407
更新日期:2018-01-01 00:00:00
abstract::Psychological consequences of exercise deprivation in habitual exercisers. The purpose of this investigation was to evaluate the influence of 3 d of exercise deprivation on selected psychological variables. Ten volunteers (4 female and 6 male) who regularly exercised 6-7 d.wk-1 for at least 45 min at a time participat...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1097/00005768-199609000-00018
更新日期:1996-09-01 00:00:00
abstract:UNLABELLED:Hiking is a recreational activity shown to offer significant positive effects on the human body. However, walking downhill and external load carriage have both been shown to increase the risk of musculoskeletal pain and injury. The use of hiking poles has been demonstrated to be successful in reducing forces...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000240328.31276.fc
更新日期:2007-01-01 00:00:00