Abstract:
:A case of human fetal renal maldevelopment following the administration of nitrogen mustard, vincristine, procarbazine, and prednisone in early pregnancy for therapy of Hodgkin's disease is reported. While these agents have been shown to be teratogenic in animal experiments, adverse fetal effects following their use during early human pregnancy have not been described. In spite of this previous experience, it has generally been recommended that these agents be withheld during the first trimester of pregnancy because of their presumed teratogenic potential. This case would seem to reinforce this recommendation.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Mennuti MT,Shepard TH,Mellman WJsubject
Has Abstractpub_date
1975-08-01 00:00:00pages
194-6issue
2eissn
0029-7844issn
1873-233Xjournal_volume
46pub_type
杂志文章abstract:OBJECTIVE:Mifepristone and oral misoprostol are typically used for medical abortion in women up to 49 days of gestation, with a 36- to 48-hour interval between the medications. Alternative routes of misoprostol administration allow for use beyond 49 days of gestation. We designed this randomized, noninferiority trial t...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/01.AOG.0000258298.35143.d2
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To evaluate an interferon (IFN)-gamma release assay in diagnosing latent tuberculosis infection in pregnant adolescents and women at risk for exposure to Mycobacterium tuberculosis. METHODS:This was a prospective study of women and adolescents receiving health care at Bellevue Hospital Outpatient Clinics in ...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章
doi:10.1097/AOG.0b013e3182546aff
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:The association of intraoperative neurologic injuries with gynecologic surgical procedures is well established. The sequelae of such injuries are usually transient and resolve with minimal intervention, although long-term disability can and does occasionally occur. The purpose of this study was to examine the...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1097/01.AOG.0000110542.53489.c6
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVE:To assess the morbidity associated with continuing the second-stage duration of labor, weighing the probability of spontaneous vaginal birth without morbidity compared with birth with serious maternal or neonatal complications. METHODS:In a retrospective cohort, we analyzed singleton, vertex births at 36 wee...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000002431
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the Interstitial Cystitis Symptom Index and Problem Index as a screening tool for interstitial cystitis, and to estimate the prevalence and risk factors for interstitial cystitis in women with chronic pelvic pain. METHODS:Forty-five women scheduled to undergo laparoscopy for chronic pelvic pain w...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(02)02087-2
更新日期:2002-08-01 00:00:00
abstract::Cervical smears taken by the wooden Ayre spatula (widely used in the United Kingdom) and by a plastic spatula (Armovical) were compared for their ability to detect dysplastic cervical epithelium and endocervical cells. At the same time, the value of taking duplicate smears was assessed. Paired cervical smears were obt...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1982-07-01 00:00:00
abstract::Cyclic progestin therapy has been widely advocated as an adjunct to postmenopausal estrogen replacement therapy to reduce the risk of endometrial carcinoma. Acceptance of this approach, however, appears to have preceded detailed evaluation of possible adverse side effects of progestins that could result in patient non...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-07-01 00:00:00
abstract::Sickle cell anemia is associated with an alarming attrition rate during pregnancy. The maternal morbidity rate, perinatal wastage rate, and the incidence of severe morbidity in both mother and child are elevated above acceptable limits. In most cases, these statistics have been compiled using conservative therapeutic ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract::One hundred patients undergoing pelvic exenteration (total 69, anterior 13, posterior 18) at the University of Michigan Medical Center from 1964-1984 are reported. All patients were followed for at least 5 years or until time of death. The overall cumulative survival was 66% at 3 years and 61% at 5 years. The age of t...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::Congenital heart block is an unusual cause of fetal bradycardia. Until recently, the diagnosis could be confirmed only by evaluation of the fetal cardiac electrical activity. Two cases are reported in which the diagnosis of atrio-ventricular (A-V) dissociation was confirmed in the antepartum period by real-time ultras...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract:OBJECTIVE:To assess long-term clinical and urodynamic outcomes of suburethral sling procedures using polytetrafluoroethylene grafts. METHODS:Between January 1986 and May 1991, 108 women underwent suburethral sling placement to treat genuine stress incontinence. At least 1 year after surgery, 62 women participated in a...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章
doi:10.1016/0029-7844(95)00098-C
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:To estimate why the live birth rate per implanted embryo is higher in twin than in singleton pregnancies. METHODS:Data from 1,159 singleton and 523 dichorionic twin pregnancies, obtained after assisted conception, were included. To account for the higher live birth rate observed in twin pregnancies, two poss...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e31823bf978
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:A multicenter, randomized placebo-controlled trial among women with singleton pregnancies and a history of spontaneous preterm birth found that weekly injections of 17 alpha-hydroxyprogesterone caproate (17P), initiated between 16 and 20 weeks of gestation, reduced preterm birth by 33%. The current study esti...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/01.AOG.0000150560.24297.4f
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:To study the clinical course and perinatal outcome of twin pregnancies discordant for anencephaly, without selective termination. METHODS:We conducted a descriptive retrospective study of 14 cases of dichorionic twin pregnancies discordant for anencephaly, which were managed expectantly in five Israeli perin...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0029-7844(95)00309-F
更新日期:1995-12-01 00:00:00
abstract::Sixty-two patients with primary amenorrhea were retrospectively categorized into 4 groups: 1) breast development absent and uterus present (29 patients), 2) breast development present and uterus absent (9 patients), 3) both breast development and uterus absent (2 patients), and 4) both breast development and uterus pr...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1981-06-01 00:00:00
abstract:OBJECTIVE:To compare the prevalence of abnormal anal cytology and high-risk human papillomavirus (HPV) among women with a history of HPV-related genital neoplasia with women without a history of HPV-related genital neoplasia. METHODS:A cross-sectional cohort study was performed from December 2012 to February 2014. Wom...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000001135
更新日期:2015-12-01 00:00:00
abstract::A new fetal scalp electrode applicator system uses a guide tube with increased curvature and a plunger mechanism to advance, rotate, and release the spiral electrode. Results of a preliminary survey among house staff who used the system in 51 patients indicated a favorable impression, with 96.1% of the applications ra...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:The experience of physical and sexual violence (victimization) is common among U.S. women and is associated with adverse health consequences. The study objectives were to estimate the prevalence of victimization in women with cancer and to examine associations with demographics, cancer screening, and cancer s...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000217694.18062.91
更新日期:2006-06-01 00:00:00
abstract::Heating of metallic IUDs during ultrasound examination has been suggested as a possible hazard to surrounding tissues. Serial temperature measurements of such devices during insonation with commercially available ultrasound equipment show no temperature changes during prolonged exposure. The results indicate that the ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1978-07-01 00:00:00
abstract:OBJECTIVE:To evaluate a new sonographic method to measure depth and width of proximal urethral dilation during coughing and Valsalva maneuver and to report its use in a group of stress-incontinent and continent women. METHODS:Fifty-eight women were evaluated, 30 with and 28 without stress incontinence proven urodynami...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(98)00420-7
更新日期:1999-03-01 00:00:00
abstract::Although cryosurgery is regularly used for treatment of cervical intraepithelial neoplasia (CIN), there are few data concerning freeze technique and attendant extension of the cryolesion. This study evaluated how to create cryolesions extensive enough to eradicate the CIN lesion completely. The way the extension of th...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract:OBJECTIVE:To estimate an institution's specific fetal loss rate after a second-trimester genetic amniocentesis. METHODS:This is a retrospective cohort study using our prenatal diagnosis database for all pregnant women presenting for care between 1990 and 2006. We compared the fetal loss rate in women who underwent amn...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e318162eb53
更新日期:2008-03-01 00:00:00
abstract::The effectiveness of the carbon dioxide laser was evaluated in the treatment of penile, anorectal, and urethral condylomata acuminata in 40 men. All but six cases of urethral condylomata were prior conventional treatment failures. Postlaser follow-up ranged between one and two years, with an average of 16 months. No p...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1984-05-01 00:00:00
abstract::Unfavorable fetal position during diagnostic obstetric ultrasound can interfere with visualization of certain structures, leading to prolonged or repeated examination. Fetal acoustic stimulation induces a fetal startle reflex and an increase in fetal movements. This report describes our experience with fetal acoustic ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::Major advances have been made in understanding the epidemiology and biology of the hepatitis B virus. Two particular developments--hepatitis B immune globulin and a new hepatitis B virus vaccine--are of special interest to obstetricians, gynecologists, and others who provide health care to women. The appropriate use o...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1983-07-01 00:00:00
abstract::A 27-year-old, previously healthy normotensive woman was admitted for hyperemesis gravidarum and treated with intravenous fluids and metoclopramide. Thereafter, a neuropsychiatric syndrome developed, with acute asymmetrical axonal motor-sensory polyneuropathy and marked anxiety, depression, irritability, and memory an...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::We previously reported surgical correction of vaginal agenesis and partial cervical atresia in an 11-year-old girl with amenorrhea and a pelvic mass. This patient, the subject of this report, conceived 7 years later and delivered at term. An abdominal cerclage was placed at 12 weeks' gestation to protect the cervix, a...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/00006250-199011001-00001
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:To determine if patient reports of urinary incontinence symptoms can predict quality of life as measured by the short forms of the Incontinence Impact Questionnaire and the Urogenital Distress Inventory, two standardized, disease-specific instruments. METHODS:Telephone surveys were conducted of 384 community...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(97)00627-3
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVE:To examine recurrent preterm birth and early term birth in women's initial and immediately subsequent pregnancies. METHODS:This retrospective cohort study included 163,889 women who delivered their first and second liveborn singleton neonates between 20 and 44 weeks of gestation in California from 2005 throu...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000001506
更新日期:2016-08-01 00:00:00
abstract::A day in obstetric-gynecologic practice in Kenya involves uterine rupture and other conditions resulting from inadequate care and facilities for labor, as well as infected abortions. Technology and equipment taken for granted in America either don't exist or don't work. Although practice is primitive in many ways, som...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00