Recurrence of Preterm Birth and Early Term Birth.

Abstract:

OBJECTIVE:To examine recurrent preterm birth and early term birth in women's initial and immediately subsequent pregnancies. METHODS:This retrospective cohort study included 163,889 women who delivered their first and second liveborn singleton neonates between 20 and 44 weeks of gestation in California from 2005 through 2011. Data from hospital discharge records and birth certificates were used for analyses. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using logistic regression models adjusted for risk factors. RESULTS:Shorter gestational duration in the first pregnancy increased the risk of subsequent preterm birth (both early, before 32 weeks of gestation, and later, from 32 to 36 weeks of gestation) as well as early term birth (37-38 weeks of gestation). Compared with women with a prior term birth, women with a prior early preterm birth (before 32 weeks of gestation) were at the highest risk for a subsequent early preterm birth (58/935 [6.2%] compared with 367/118,505 [0.3%], adjusted OR 23.3, 95% CI 17.2-31.7). Women with a prior early term birth had more than a twofold increased risk for subsequent preterm birth (before 32 weeks of gestation: 171/36,017 [0.5%], adjusted OR 2.0, 95% CI 1.6-2.3; from 32 to 36 weeks of gestation: 2,086/36,017 [6.8%], adjusted OR 3.0, 95% CI 2.9-3.2) or early term birth (13,582/36,017 [37.7%], adjusted OR 2.2, 95% CI 2.2-2.3). CONCLUSION:Both preterm birth and early term birth are associated with these outcomes in a subsequent pregnancy. Increased clinical attention and research efforts may benefit from a focus on women with a prior early term birth as well as those with prior preterm birth.

journal_name

Obstet Gynecol

authors

Yang J,Baer RJ,Berghella V,Chambers C,Chung P,Coker T,Currier RJ,Druzin ML,Kuppermann M,Muglia LJ,Norton ME,Rand L,Ryckman K,Shaw GM,Stevenson D,Jelliffe-Pawlowski LL

doi

10.1097/AOG.0000000000001506

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

364-372

issue

2

eissn

0029-7844

issn

1873-233X

pii

00006250-201608000-00021

journal_volume

128

pub_type

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