Evaluation of methods for determination of a reconstructed history of gene sequence evolution.

abstract：:The selective constraints influencing mRNA editing in plant organelles are largely unknown. To investigate these, we compared patterns of editing between monocot and dicot mitochondrial mRNA. On average, 24% of sites that are edited form C to U in one species have been substituted during evolution by a genomic T in th...

journal_title：Molecular biology and evolution

authors： Shields DC,Wolfe KH

更新日期：1997-03-01 00:00:00

abstract：:Cyanobacteria contain up to three highly divergent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) genes: gap1, gap2, and gap3. Genes gap1 and gap2 are closely related at the sequence level to the nuclear genes encoding cytosolic and chloroplast GAPDH of higher plants and have recently been shown to play distinct key...

journal_title：Molecular biology and evolution

authors： Figge RM,Schubert M,Brinkmann H,Cerff R

更新日期：1999-04-01 00:00:00

abstract：:There is increasing evidence that X chromosomes have an unusual complement of genes, especially genes that have sex-specific expression. However, whereas in worm and fly the X chromosome has a dearth of male-specific genes, in mice genes that are uniquely expressed in spermatogonia are especially abundant on the X chr...

journal_title：Molecular biology and evolution

authors： Lercher MJ,Urrutia AO,Hurst LD

更新日期：2003-07-01 00:00:00

abstract：:We report the results of a phylogenetic survey of the retrotransposon copia in the melanogaster subgroup of the Drosophila genus. The polymerase chain reaction was used to amplify the copia 5' long terminal repeat and the adjacent untranslated leader region from representative melanogaster subgroup species. Restrictio...

journal_title：Molecular biology and evolution

authors： Jordan IK,McDonald JF

更新日期：1998-09-01 00:00:00

abstract：:Hybridization and polyploidization are important evolutionary processes whose impacts range from the alteration of gene expression and phenotypic variation to the triggering of asexual reproduction. We investigated fishes of the Cobitis taenia-elongatoides hybrid complex, which allowed us to disentangle the direct eff...

journal_title：Molecular biology and evolution

authors： Bartoš O,Röslein J,Kotusz J,Paces J,Pekárik L,Petrtýl M,Halačka K,Štefková Kašparová E,Mendel J,Boroń A,Juchno D,Leska A,Jablonska O,Benes V,Šídová M,Janko K

更新日期：2019-09-01 00:00:00

abstract：:Lineage-specific gene duplications contribute to a large variation in specialized metabolites among different plant species. There is also considerable variability in the specialized metabolites within a single plant species. However, it is unclear whether copy number variations (CNVs) derived from gene duplication ev...

journal_title：Molecular biology and evolution

authors： Shirai K,Matsuda F,Nakabayashi R,Okamoto M,Tanaka M,Fujimoto A,Shimizu M,Shinozaki K,Seki M,Saito K,Hanada K

更新日期：2017-12-01 00:00:00

abstract：:Although many phylogenetic studies have focused on developing hypotheses about relationships, advances in data collection and computation have increased the feasibility of collecting large independent data sets to rigorously test controversial hypotheses or carefully assess artifacts that may be misleading. One such r...

journal_title：Molecular biology and evolution

authors： Wang N,Braun EL,Kimball RT

更新日期：2012-02-01 00:00:00

abstract：:Forty-six strains derived from American and French natural populations of Drosophila melanogaster were tested for the presence and activity of hobo elements by using Southern blotting and a gonadal dysgenesis assay. The oldest available strains exhibited weak detectable hybridization to the hobo-element probe and reve...

journal_title：Molecular biology and evolution

authors： Pascual L,Periquet G

更新日期：1991-05-01 00:00:00

abstract：:A 32-kb region including the Adh structural gene was analyzed with six restriction endonucleases in 20 lines of Drosophila pseudoobscura, one line of D. persimilis, and one line of D. miranda. Nineteen lines of D. pseudoobscura from a single population were estimated to be polymorphic at one in every 15 nucleotides (p...

journal_title：Molecular biology and evolution

authors： Schaeffer SW,Aquadro CF,Anderson WW

更新日期：1987-05-01 00:00:00

abstract：:In a striking contrast, matK is one of the most rapidly evolving plastid genes and also one of the few plastid genes to be retained in all nonphotosynthetic plants examined to date. DNA sequences of this region were obtained from photosynthetic and nonphotosynthetic plants of Orobanchaceae and their relatives. The res...

journal_title：Molecular biology and evolution

authors： Young ND,dePamphilis CW

更新日期：2000-12-01 00:00:00

abstract：:In numerous species, individual dispersal is restricted in space so that "continuous" populations evolve under isolation by distance. A method based on individual genotypes assuming a lattice population model was recently developed to estimate the product Dsigma2, where D is the population density and sigma2 is the av...

journal_title：Molecular biology and evolution

authors： Leblois R,Estoup A,Rousset F

更新日期：2003-04-01 00:00:00

abstract：:Some of the assumptions underlying estimates of DNA and protein sequence divergence are examined. A solution for the variance of these estimates that allows for different mutation rates and different population sizes in each species and for an arbitrary structure in the initial population is obtained. It is shown that...

journal_title：Molecular biology and evolution

authors： Golding GB

更新日期：1983-12-01 00:00:00

abstract：:Human histatins are a family of low-M(r), neutral to very basic, histidine-rich salivary polypeptides. They probably function as part of the nonimmune host defense system in the oral cavity. A 39-kb region of DNA containing the HIS1 and HIS2 genes was isolated from two human genomic phage libraries as a series of over...

journal_title：Molecular biology and evolution

authors： Sabatini LM,Ota T,Azen EA

更新日期：1993-05-01 00:00:00

abstract：:Based on previous observations that newly inserted LINEs and SINEs have particularly long 3' A-tails, which shorten rapidly during evolutionary time, we have analyzed the rat and mouse genomes for evidence of recently inserted SINEs and LINEs. We find that the youngest predicted subfamilies of rodent identifier (ID) e...

journal_title：Molecular biology and evolution

authors： Odom GL,Robichaux JL,Deininger PL

更新日期：2004-11-01 00:00:00

abstract：:The occurrence of a fish-specific genome duplication (FSGD) in the lineage leading to teleost fishes is widely accepted, but the consequences of this event remain elusive. Teleosts, and the cichlid fishes from the species flocks in the East African Great Lakes in particular, evolved a unique complexity and diversity o...

journal_title：Molecular biology and evolution

authors： Braasch I,Salzburger W,Meyer A

更新日期：2006-06-01 00:00:00

abstract：:A sample of the second largest subunit of low-copy nuclear RNA polymerase II (rpb2) sequences from Malvaceae subfamily Malvoideae suggests that rpb2 has been duplicated early in the subfamily's history. Hibiscus and related taxa possess two rpb2 genes, both of which produce congruent phylogenetic patterns that are lar...

journal_title：Molecular biology and evolution

authors： Pfeil BE,Brubaker CL,Craven LA,Crisp MD

更新日期：2004-07-01 00:00:00

abstract：:Despite its poorly adapted codon usage, HIV-1 replicates and is expressed extremely well in human host cells. HIV-1 has recently been shown to package non-lysyl transfer RNAs (tRNAs) in addition to the tRNA(Lys) needed for priming reverse transcription and integration of the HIV-1 genome. By comparing the codon usage ...

journal_title：Molecular biology and evolution

authors： van Weringh A,Ragonnet-Cronin M,Pranckeviciene E,Pavon-Eternod M,Kleiman L,Xia X

更新日期：2011-06-01 00:00:00

abstract：:Spatial distribution and clustering of repetitive elements are extensively studied during the last years, as well as their colocalization with other genomic components. Here we investigate the large-scale features of Alu and LINE1 spatial arrangement in the human genome by studying the size distribution of interrepeat...

journal_title：Molecular biology and evolution

authors： Sellis D,Provata A,Almirantis Y

更新日期：2007-11-01 00:00:00

abstract：:Insertion and deletion (indel)-based analyses have great potential for rooting the tree of life, but their use has been limited because they require ubiquitous sequences that have not been horizontally/laterally transferred. Very few such sequences exist. Here we describe and demonstrate a new algorithm that can use n...

journal_title：Molecular biology and evolution

authors： Lake JA,Herbold CW,Rivera MC,Servin JA,Skophammer RG

更新日期：2007-01-01 00:00:00

abstract：:Operons coding for the enzyme arsenite oxidase have been detected in the genomes from Archaea and Bacteria by Blast searches using the amino acid sequences of the respective enzyme characterized in two different beta-proteobacteria as templates. Sequence analyses show that in all these species, arsenite oxidase is tra...

journal_title：Molecular biology and evolution

authors： Lebrun E,Brugna M,Baymann F,Muller D,Lièvremont D,Lett MC,Nitschke W

更新日期：2003-05-01 00:00:00

abstract：:The proportion of functional sequence in the human genome is currently a subject of debate. The most widely accepted figure is that approximately 5% is under purifying selection. In Drosophila, estimates are an order of magnitude higher, though this corresponds to a similar quantity of sequence. These estimates depend...

journal_title：Molecular biology and evolution

authors： Oldmeadow C,Mengersen K,Mattick JS,Keith JM

更新日期：2010-04-01 00:00:00

abstract：:Polymerases are essential for life, being responsible for replication, transcription, and the repair of nucleic acid molecules. Those that share a right-hand-shaped fold and catalytic site structurally similar to the DNA polymerase I of Escherichia coli may catalyze RNA- or DNA-dependent RNA polymerization, reverse tr...

journal_title：Molecular biology and evolution

authors： Mönttinen HA,Ravantti JJ,Stuart DI,Poranen MM

更新日期：2014-10-01 00:00:00

abstract：:Proteins present in the seminal fluid of Drosophila melanogaster (accessory gland proteins Acps) contribute to female postmating behavioral changes, sperm storage, sperm competition, and immunity. Consequently, male-female coevolution and host-pathogen interactions are thought to underlie the rapid, adaptive evolution...

journal_title：Molecular biology and evolution

authors： Wong A,Turchin MC,Wolfner MF,Aquadro CF

更新日期：2008-03-01 00:00:00

abstract：:Interspecific hybridization is one of the major factors leading to phylogenetic incongruence among loci, but the knowledge is still limited about the potential of each locus to introgress between species. By directly sequencing three DNA regions: chloroplast DNAs (matK gene and trnL-F noncoding region), the nuclear ri...

journal_title：Molecular biology and evolution

authors： Okuyama Y,Fujii N,Wakabayashi M,Kawakita A,Ito M,Watanabe M,Murakami N,Kato M

更新日期：2005-02-01 00:00:00

abstract：:The adaptive radiation of cichlid fishes in East African Lake Malawi encompasses over 500 species that are believed to have evolved within the last 800,000 years from a common founder population. It has been proposed that hybridization between ancestral lineages can provide the genetic raw material to fuel such except...

journal_title：Molecular biology and evolution

authors： Svardal H,Quah FX,Malinsky M,Ngatunga BP,Miska EA,Salzburger W,Genner MJ,Turner GF,Durbin R

更新日期：2020-04-01 00:00:00

abstract：:DNA fingerprinting exhibits multilocus genotypes of individuals, detected by the use of a single multilocus probe. Consequently, population data on DNA fingerprinting do not provide a complete characterization of the genetic variation in terms of allele-frequency distributions, since neither the number of loci nor the...

journal_title：Molecular biology and evolution

authors： Jin L,Chakraborty R

更新日期：1994-01-01 00:00:00

abstract：:Plants can show long-term effects of environmental stresses and in some cases a stress "memory" has been reported to persist across generations, potentially mediated by epigenetic mechanisms. However, few documented cases exist of transgenerational effects that persist for multiple generations and it remains unclear i...

journal_title：Molecular biology and evolution

authors： Morgado L,Preite V,Oplaat C,Anava S,Ferreira de Carvalho J,Rechavi O,Johannes F,Verhoeven KJF

更新日期：2017-08-01 00:00:00

abstract：:Hepcidin is a small bioactive peptide with dual roles as an antimicrobial peptide and as the principal hormonal regulator of iron homeostasis in human and mouse. Hepcidin homologs of very similar structures are found in lower vertebrates, all comprise approximately 20-25 amino acids with 8 highly conserved cysteines f...

journal_title：Molecular biology and evolution

authors： Xu Q,Cheng CH,Hu P,Ye H,Chen Z,Cao L,Chen L,Shen Y,Chen L

更新日期：2008-06-01 00:00:00

abstract：:The RIIIS/J inbred mouse strain is a model for type 1 von Willebrand disease (VWD), a common human bleeding disorder. Low von Willebrand factor (VWF) levels in RIIIS/J are due to a regulatory mutation, Mvwf1, which directs a tissue-specific switch in expression of a glycosyltransferase, B4GALNT2, from intestine to blo...

journal_title：Molecular biology and evolution

authors： Johnsen JM,Teschke M,Pavlidis P,McGee BM,Tautz D,Ginsburg D,Baines JF

更新日期：2009-03-01 00:00:00

abstract：:The increased interest in asexual organisms calls for in-depth studies of asexual complexes that actively give rise to new clones. We present an extensive molecular study of the Otiorhynchus scaber (Coleoptera, Curculionidae) weevil system. Three forms have traditionally been recognized: diploid sexuals, triploid, and...

journal_title：Molecular biology and evolution

authors： Stenberg P,Lundmark M,Knutelski S,Saura A

更新日期：2003-10-01 00:00:00