The Legacy of Sexual Ancestors in Phenotypic Variability, Gene Expression, and Homoeolog Regulation of Asexual Hybrids and Polyploids.

abstract：:For populations to maintain optimal fitness, harmful mutations must be efficiently purged from the genome. Yet, under circumstances that diminish the effectiveness of natural selection, such as the process of plant and animal domestication, deleterious mutations are predicted to accumulate. Here, we compared the load ...

journal_title：Molecular biology and evolution

authors： Renaut S,Rieseberg LH

更新日期：2015-09-01 00:00:00

abstract：:The complete mitochondrial DNA (mtDNA) control region was sequenced for 71 individuals from five species of the rodent genus Clethrionomys both to understand patterns of variation and to explore the existence of previously described domains and other elements. Among species, the control region ranged from 942 to 971 b...

journal_title：Molecular biology and evolution

authors： Matson CW,Baker RJ

更新日期：2001-08-01 00:00:00

abstract：:Standard methods of phylogenetic reconstruction are based on models that assume homogeneity of nucleotide composition among taxa. However, this assumption is often violated in biological data sets. In this study, we examine possible effects of nucleotide heterogeneity among lineages on the phylogenetic reconstruction ...

journal_title：Molecular biology and evolution

authors： Herbeck JT,Degnan PH,Wernegreen JJ

更新日期：2005-03-01 00:00:00

abstract：:An attempt to use phylogenetic invariants for tree reconstruction was made at the end of the 80s and the beginning of the 90s by several researchers (the initial idea due to Lake [1987] and Cavender and Felsenstein [1987]). However, the efficiency of methods based on invariants is still in doubt (Huelsenbeck 1995; Jin...

journal_title：Molecular biology and evolution

authors： Casanellas M,Fernández-Sánchez J

更新日期：2007-01-01 00:00:00

abstract：:Despite its population, geographic size, and emerging economic importance, disproportionately little genome-scale research exists into genetic factors that predispose Brazilians to disease, or the population genetics of risk. After identification of suitable proxy populations and careful analysis of tri-continental ad...

journal_title：Molecular biology and evolution

authors： Mychaleckyj JC,Havt A,Nayak U,Pinkerton R,Farber E,Concannon P,Lima AA,Guerrant RL

更新日期：2017-03-01 00:00:00

abstract：:Transfer RNA (tRNA) is essential for the translation of genetic information into proteins, and understanding its molecular evolution is important if we are to understand the genetic code. In general, long variable-arm (V-arm) structures form in tRNA(Leu), tRNA(Ser), and bacterial and organellar tRNA(Tyr). However, as ...

journal_title：Molecular biology and evolution

authors： Hamashima K,Tomita M,Kanai A

更新日期：2016-02-01 00:00:00

abstract：:In order to investigate divergence of immune regulation among Drosophila species, we have engaged in a study of innate immune function in F1 hybrids of Drosophila melanogaster and D. simulans. If pathways have diverged between the species such that incompatibilities have arisen between interacting components of the im...

journal_title：Molecular biology and evolution

authors： Hill-Burns EM,Clark AG

更新日期：2010-11-01 00:00:00

abstract：:Deletion rates are thought to be important factors in determining the genome size of organisms in nature. Although it is indisputable that deletions, and thus deletion rates, affect genome size, it is unclear how, or indeed if, genome size is regulated via the deletion rate. Here, we employ a mathematical model to det...

journal_title：Molecular biology and evolution

authors： Pettersson ME,Kurland CG,Berg OG

更新日期：2009-06-01 00:00:00

abstract：:Large phylogenomics data sets require fast tree inference methods, especially for maximum-likelihood (ML) phylogenies. Fast programs exist, but due to inherent heuristics to find optimal trees, it is not clear whether the best tree is found. Thus, there is need for additional approaches that employ different search st...

journal_title：Molecular biology and evolution

authors： Nguyen LT,Schmidt HA,von Haeseler A,Minh BQ

更新日期：2015-01-01 00:00:00

abstract：:The mitochondrial inner and outer membranes are composed of a variety of integral membrane proteins, assembled into the membranes posttranslationally. The small translocase of the inner mitochondrial membranes (TIMs) are a group of approximately 10 kDa proteins that function as chaperones to ferry the imported protein...

journal_title：Molecular biology and evolution

authors： Gentle IE,Perry AJ,Alcock FH,Likić VA,Dolezal P,Ng ET,Purcell AW,McConnville M,Naderer T,Chanez AL,Charrière F,Aschinger C,Schneider A,Tokatlidis K,Lithgow T

更新日期：2007-05-01 00:00:00

abstract：:Genes encoding DNA replication proteins have been frequently exchanged between cells and mobile elements, such as viruses or plasmids. This raises potential problems to reconstruct their history. Here, we combine phylogenetic and genomic context analyses to study the evolution of the replicative minichromosome mainten...

journal_title：Molecular biology and evolution

authors： Krupovic M,Gribaldo S,Bamford DH,Forterre P

更新日期：2010-12-01 00:00:00

abstract：:Although initial studies suggested that Denisovan ancestry was found only in modern human populations from island Southeast Asia and Oceania, more recent studies have suggested that Denisovan ancestry may be more widespread. However, the geographic extent of Denisovan ancestry has not been determined, and moreover the...

journal_title：Molecular biology and evolution

authors： Qin P,Stoneking M

更新日期：2015-10-01 00:00:00

abstract：:The plant pathogen Phytophthora infestans emerged in Europe in 1845, triggering the Irish potato famine and massive European potato crop losses that continued until effective fungicides were widely employed in the 20th century. Today the pathogen is ubiquitous, with more aggressive and virulent strains surfacing in re...

journal_title：Molecular biology and evolution

authors： Martin MD,Ho SY,Wales N,Ristaino JB,Gilbert MT

更新日期：2014-06-01 00:00:00

abstract：:Protein-protein interaction networks have evolved mainly through connectivity rewiring and gene duplication. However, how protein function influences these processes and how a network grows in time have not been well studied. Using protein-protein interaction data and genomic data from the budding yeast, we first exam...

journal_title：Molecular biology and evolution

authors： Prachumwat A,Li WH

更新日期：2006-01-01 00:00:00

abstract：:Two longstanding issues on the molecular clock hypothesis are studied in this article. First, is there a global molecular clock in mammals? Although many authors have observed unequal rates of nucleotide substitution among mammalian lineages, some authors have proposed a global clock for all eutherians, i.e., a single...

journal_title：Molecular biology and evolution

authors： Yi S,Ellsworth DL,Li WH

更新日期：2002-12-01 00:00:00

abstract：:Variation in rates of molecular evolution now appears to be widespread. The demonstration that body size is correlated with rates of molecular evolution suggests that physiological and ecological factors may be involved in molecular rate variation, but large-scale comparative studies are still lacking. Here, we use co...

journal_title：Molecular biology and evolution

authors： Nunn GB,Stanley SE

更新日期：1998-10-01 00:00:00

abstract：:Sequence variation among 10 alleles of the alcohol dehydrogenase (Adh) gene of the Hawaiian drosophilid D. mimica was analyzed with reference to the evolutionary history of the Hawaiian subgroup as well as to levels and patterns of polymorphism of the Adh gene in continental drosophilid species. The Adh gene of D. mim...

journal_title：Molecular biology and evolution

authors： Ayala FJ,Campbell CD,Selander RK

更新日期：1996-12-01 00:00:00

abstract：:As the oomycete pathogen causing potato late blight disease, Phytophthora infestans triggered the famous 19th-century Irish potato famine and remains the leading cause of global commercial potato crop destruction. But the geographic origin of the genotype that caused this devastating initial outbreak remains disputed,...

journal_title：Molecular biology and evolution

authors： Martin MD,Vieira FG,Ho SY,Wales N,Schubert M,Seguin-Orlando A,Ristaino JB,Gilbert MT

更新日期：2016-02-01 00:00:00

abstract：:We present QNet, a method for constructing split networks from weighted quartet trees. QNet can be viewed as a quartet analogue of the distance-based Neighbor-Net (NNet) method for network construction. Just as NNet, QNet works by agglomeratively computing a collection of circular weighted splits of the taxa set which...

journal_title：Molecular biology and evolution

authors： Grünewald S,Forslund K,Dress A,Moulton V

更新日期：2007-02-01 00:00:00

abstract：:Molecular clocks are routinely tested for linearity using a relative rate test and routinely calibrated against the geological time scale using a single or average paleontologically determined time of divergence between living taxa. The relative rate test is a test of parallel rate equality, not a test of rate constan...

journal_title：Molecular biology and evolution

authors： Gingerich PD

更新日期：1986-05-01 00:00:00

abstract：:Multipartite genomes, containing at least two large replicons, are found in diverse bacteria; however, the advantage of this genome structure remains incompletely understood. Here, we perform comparative genomics of hundreds of finished β-proteobacterial genomes to gain insights into the role and emergence of multipar...

journal_title：Molecular biology and evolution

authors： diCenzo GC,Mengoni A,Perrin E

更新日期：2019-03-01 00:00:00

abstract：:The complete nucleotide sequence of the mt (mitochondrial) and cp (chloroplast) genomes of the unicellular green alga Ostreococcus tauri has been determined. The mt genome assembles as a circle of 44,237 bp and contains 65 genes. With an overall average length of only 42 bp for the intergenic regions, this is the most...

journal_title：Molecular biology and evolution

authors： Robbens S,Derelle E,Ferraz C,Wuyts J,Moreau H,Van de Peer Y

更新日期：2007-04-01 00:00:00

abstract：:We report the presence of four nuclear paralogs of a 380-bp segment of cytochrome b in callitrichine primates (marmosets and tamarins). The mitochondrial cytochrome b sequence and each nuclear paralog were obtained from several species, allowing multiple comparisons of rates and patterns of substitution both between m...

journal_title：Molecular biology and evolution

authors： Mundy NI,Pissinatti A,Woodruff DS

更新日期：2000-07-01 00:00:00

abstract：:Liver and intestinal flukes of the family Fasciolidae cause zoonotic food-borne infections that impact both agriculture and human health throughout the world. Their evolutionary history and the genetic basis underlying their phenotypic and ecological diversity are not well understood. To close that knowledge gap, we c...

journal_title：Molecular biology and evolution

authors： Choi YJ,Fontenla S,Fischer PU,Le TH,Costábile A,Blair D,Brindley PJ,Tort JF,Cabada MM,Mitreva M

更新日期：2020-01-01 00:00:00

abstract：:A fundamental goal in evolutionary biology is to identify the molecular changes responsible for adaptive evolution. In this study, we describe a genetic analysis to determine whether the molecular changes contributing to adaptive flower color divergence in Mimulus aurantiacus affect gene expression or enzymatic activi...

journal_title：Molecular biology and evolution

authors： Streisfeld MA,Rausher MD

更新日期：2009-02-01 00:00:00

abstract：:Pathogen recognition is the first step of immune reactions. In animals and plants, direct or indirect pathogen recognition is often mediated by a wealth of fast-evolving receptors, many of which contain ligand-binding and signal transduction domains, such as leucine-rich or tetratricopeptide repeat (LRR/TPR) and NB-AR...

journal_title：Molecular biology and evolution

authors： Zambounis A,Elias M,Sterck L,Maumus F,Gachon CM

更新日期：2012-04-01 00:00:00

abstract：:Forty-six strains derived from American and French natural populations of Drosophila melanogaster were tested for the presence and activity of hobo elements by using Southern blotting and a gonadal dysgenesis assay. The oldest available strains exhibited weak detectable hybridization to the hobo-element probe and reve...

journal_title：Molecular biology and evolution

authors： Pascual L,Periquet G

更新日期：1991-05-01 00:00:00

abstract：:Animal microRNAs (miRNAs) are short RNAs that function as posttranscriptional regulators of gene expression by binding to the target mRNAs. Noting that some miRNAs are highly conserved in evolution, we explored the possibility of evolutionary conservation of their targets. We identified human orthologues of experiment...

journal_title：Molecular biology and evolution

authors： Lin YC,Hsieh LC,Kuo MW,Yu J,Kuo HH,Lo WL,Lin RJ,Yu AL,Li WH

更新日期：2007-11-01 00:00:00

abstract：:Here we use phylogenomics with expressed sequence tag (EST) data from the ecologically important coccolithophore-forming alga Emiliania huxleyi and the plastid-lacking cryptophyte Goniomonas cf. pacifica to establish their phylogenetic positions in the eukaryotic tree. Haptophytes and cryptophytes are members of the p...

journal_title：Molecular biology and evolution

authors： Hackett JD,Yoon HS,Li S,Reyes-Prieto A,Rümmele SE,Bhattacharya D

更新日期：2007-08-01 00:00:00

abstract：:Although any genotype-phenotype relationships are a result of evolution, little is known about how natural selection and neutral drift, two distinct driving forces of evolution, operate to shape the relationships. By analyzing ∼500 yeast quantitative traits, we reveal a basic "supervisor-worker" gene architecture unde...

journal_title：Molecular biology and evolution

authors： Chen H,Wu CI,He X

更新日期：2018-03-01 00:00:00