Atypical and anaplastic meningiomas--does the new WHO-classification of brain tumours affect the indication for postoperative irradiation?

Abstract:

:We retrospectively analysed 13 patients (pts.) treated at the University of Tübingen from 1985 to 1993 to evaluate the results of radiation therapy (XRT) given as an adjuvant to totally or subtotally resected meningiomas. The overall survival was 38% at five years with a probability of relapse of 50% at this time. Reclassification of the tumours according to the new WHO-classification of brain tumours [14] revealed 10 grade-II-tumours (atypical meningioma) and 3 grade-III-tumours (anaplastic meningioma). Radiotherapy failed in all 3 pts. with macroscopically incomplete resection (Simpson's grade IV), who died with relapse between 4 and 51 months after radiotherapy. 5 out of 10 pts. with grade-II-tumours relapsed. All 3 pts. with grade-III-tumours died with relapse between 6 and 21 months after XRT. Morbidity was seen in 2 pts. after irradiation with 60 GY (ICRU dose specification). Complete surgical exstirpation offers the best possibility of tumour control. Grade-III-tumours should be irradiated whatever the extent of the primary surgery was. Our results might indicate a possible indication for XRT in pts. with atypical grade-II-tumours especially when radical surgery must be in doubt. Prospective multicentre trials are warranted to prove the prognostic value of the new WHO-classification for atypical and anaplastic meningiomas and to define the ultimate role of radiotherapy in this setting.

journal_name

Acta Neurochir (Wien)

journal_title

Acta neurochirurgica

authors

Hoffmann W,Mühleisen H,Hess CF,Kortmann RD,Schmidt B,Grote EH,Bamberg M

doi

10.1007/BF02187764

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

171-8

issue

3-4

eissn

0001-6268

issn

0942-0940

journal_volume

135

pub_type

杂志文章
  • Cerebral blood flow and oxidative brain metabolism during and after moderate and profound arterial hypoxaemia.

    abstract::In anaesthetized artificially ventilated dogs, the effect of graded arterial hypoxaemia on cerebral blood flow (CBF) and on the oxidative carbohydrate metabolism of the brain was tested. It is shown that the hypoxic vasodilatory influence on cerebral vessels is present even at moderate systemic hypoxaemia, provide tha...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01886665

    authors: Hamer J,Hoyer S,Alberti E,Weinhardt F

    更新日期:1976-01-01 00:00:00

  • Deep brain stimulation of the subthalamic nucleus versus the zona incerta in the treatment of essential tremor.

    abstract:BACKGROUND:Deep brain stimulation (DBS) is an effective treatment for essential tremor (ET). Currently the ventrolateral thalamus is the target of choice, but the posterior subthalamic area (PSA), including the caudal zona incerta (cZi), has demonstrated promising results, and the subthalamic nucleus (STN) has been sug...

    journal_title:Acta neurochirurgica

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00701-011-1157-4

    authors: Blomstedt P,Sandvik U,Linder J,Fredricks A,Forsgren L,Hariz MI

    更新日期:2011-12-01 00:00:00

  • Virtual surgical planning for superficial temporal artery to middle cerebral artery bypass using three-dimensional digital subtraction angiography.

    abstract:OBJECTIVE:To introduce reliable and minimally invasive virtual surgical planning for superficial temporal artery to middle cerebral artery (STA-MCA) bypass surgery using three-dimensional (3-D) rotational reconstruction digital subtraction angiography (DSA). METHODS:Twenty-eight consecutive patients (11 women and 17 m...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-010-0681-y

    authors: Nakagawa I,Kurokawa S,Tanisaka M,Kimura R,Nakase H

    更新日期:2010-09-01 00:00:00

  • Image-guided percutaneous biopsy of peripheral nerve tumors of indeterminate nature: risks and benefits.

    abstract:BACKGROUND:Usual management of peripheral nerve tumors is to avoid biopsy in those that are likely benign; the risk of biopsy outweighs the benefit of definitive tissue diagnosis. Biopsy of presumed malignant lesions is performed widely. There is a subset of peripheral nerve tumors that are not easily categorized as be...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-020-04257-1

    authors: Pendleton C,Spinner RJ

    更新日期:2020-06-01 00:00:00

  • Neuromuscular choristoma-associated desmoid-type fibromatosis: Establishing a nerve territory concept.

    abstract:INTRODUCTION:Desmoid-type fibromatosis (DTF) frequently arises in patients with neuromuscular choristoma (NMC). We hypothesize that NMC-associated DTF occurs in soft tissues innervated by the NMC-affected nerve, and arises from CTNNB1-mutated (myo) fibroblasts within or directly adjacent to the NMC. MATERIALS AND METH...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-019-04178-8

    authors: Maldonado AA,Spinner RJ,Broski SM,Stone JJ,Howe BM,Carter JM

    更新日期:2020-05-01 00:00:00

  • Early radiologically proven rebleeding from intracranial cavernous angiomas: report of 6 cases and review of the literature.

    abstract::Although intracranial cavernomas are known to cause haemorrhage, data concerning the frequency, severity and delay of recurrent bleedings are controversial. We report a series of 6 patients with histologically proven cavernoma, presenting with early clinical signs and radiological proof of rebleeding, that is occurrin...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章,评审

    doi:10.1007/BF01411299

    authors: Duffau H,Capelle L,Sichez JP,Faillot T,Bitar A,Arthuis F,Van Effenterre R,Fohanno D

    更新日期:1997-01-01 00:00:00

  • Patient-reported experience measures in patients undergoing navigated transcranial magnetic stimulation (nTMS): the introduction of nTMS-PREMs.

    abstract:BACKGROUND:Patient-reported experience measures (PREMs) are a unique measure of experience of patients which can help address the quality of care of the patients. OBJECTIVE:Our aim of the study is to collect quality of care outcomes with our newly navigated transcranial magnetic stimulation patient-reported experience...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-020-04268-y

    authors: Patel S,Ghimire P,Lavrador JP,Jung J,Gullan R,Ashkan K,Bhangoo R,Vergani F

    更新日期:2020-07-01 00:00:00

  • Attenuation of cerebral vasospasm and secondary injury by testosterone following experimental subarachnoid hemorrhage in rabbit.

    abstract:BACKGROUND:The vasodilatator effects of testosterone have been widely studied and demonstrated. Based on previous studies of these vasodilatatory activities, we hypothesized that testosterone might have potential effects on subarachnoid hemorrhage-induced cerebral vasospasm. METHODS:Thirty-two adult male New Zealand w...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-014-2211-9

    authors: Gürer B,Turkoglu E,Kertmen H,Karavelioglu E,Arikok AT,Sekerci Z

    更新日期:2014-11-01 00:00:00

  • Assessment and prognosis of coma after head injury.

    abstract::The Glasgow Coma Scale, based upon eye opening, verbal and motor responses has proved a practical and consistent means of monitoring the state of head injured patients. Observations made in the early stages after injury define the depth and duration of coma and, when combined with clinical features such as a patient's...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01405862

    authors: Teasdale G,Jennett B

    更新日期:1976-01-01 00:00:00

  • Is the outcome of traditional lumbar disc surgery related to the size of the exposure?

    abstract::The purpose of this study was to evaluate whether wide surgical exposures result in poorer outcome of lumbar disc surgery compared to smaller traditional exposures. The aim was also to assess if a dural tear has any impact on the postoperative clinical outcome. One hundred and twenty-two patients (56 women and 66 men,...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01411260

    authors: Graver V,Ljunggren AE,Magnaes B,Loeb M,Lie H

    更新日期:1996-01-01 00:00:00

  • Manual for clinical language tractography.

    abstract:BACKGROUND:We introduce a user-friendly, standardized protocol for tractography of the major language fiber bundles. METHOD:The introduced method uses dMRI images for tractography whereas the ROI definition is based on structural T1 MPRAGE MRI templates, without normalization to MNI space. ROIs for five language-relev...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-019-03899-0

    authors: Fekonja L,Wang Z,Bährend I,Rosenstock T,Rösler J,Wallmeroth L,Vajkoczy P,Picht T

    更新日期:2019-06-01 00:00:00

  • Telescopic suction tube for microsurgery.

    abstract::An adjustable telescopic suction tube has been developed for microsurgery. Owing to this innovation, the surgeon can easily set the suction tube to a suitable length by gently pulling the end of the telescopic tube out or in. ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01401302

    authors: Boström S,Nilsson I

    更新日期:1992-01-01 00:00:00

  • Recurrent infrasellar clival craniopharyngioma.

    abstract::The patient is a 44-year-old man who underwent resection of a posterior nasopharynx tumor 12 years earlier via left lateral rhinotomy approach. The final pathological analysis indicated the tumor was a craniopharyngioma, and the patient subsequently underwent focal radiation. The patient returned to medical attention ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-007-1168-3

    authors: Ragel BT,Bishop FS,Couldwell WT

    更新日期:2007-01-01 00:00:00

  • Vasomodulatory effects of the angiotensin II type 1 receptor antagonist losartan on experimentally induced cerebral vasospasm after subarachnoid haemorrhage.

    abstract:BACKGROUND:Cerebral vasospasm following subarachnoid haemorrhage (SAH) remains one of the major factors contributing to poor overall patient outcome. Prostaglandin F2-alpha (PGF2a) induces vasoconstriction. After SAH, PGF2a leads to cerebral inflammation and enhanced vasoconstriction, resulting in cerebral vasospasm. L...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-017-3419-2

    authors: Wanderer S,Mrosek J,Gessler F,Seifert V,Konczalla J

    更新日期:2018-02-01 00:00:00

  • Bilateral chylothorax following anterior cervical spine surgery.

    abstract::Bilateral chylothorax following anterior cervical spine surgery is very rare. This report documents the first case of chylothorax after anterior cervical spine surgery through a right-side surgical approach. Unidentified chyle leakage can easily remain unrecognized and, thus, is difficult to treat. For early diagnosis...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-017-3294-x

    authors: Bae JS,Park JH,Jang IT

    更新日期:2017-10-01 00:00:00

  • Anterior decompression and fusion for thoracolumbar fractures with neurological deficits.

    abstract::Anterior spinal decompression and fusion was used as the primary treatment for thoracolumbar fractures in eleven patients with neurological deficits. Each patient achieved stability by interbody fusion. Significant progressive kyphosis did not occur. No patients with a complete neurological deficit was improved by ope...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01664845

    authors: Young B,Brooks WH,Tibbs PA

    更新日期:1981-01-01 00:00:00

  • Persistent embryonic veins in arteriovenous malformations of the posterior fossa.

    abstract::In the arteriovenous malformations of the posterior fossa the arterial feeders and the dural venous sinuses can be identified in anatomical terminology. The arterialised veins which do not conform to adult anatomical descriptions represent the persistent embryonic veins of the metencephalic and myelencephalic segments...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01406021

    authors: Vidyasagar C

    更新日期:1979-01-01 00:00:00

  • Cold as a therapeutic agent.

    abstract::The use of cold as a therapeutic agent has a long and colorful history. The Edwin Smith Papyrus, the most ancient medical text known, dated 3500 B.C., made numerous references to the use of cold as therapy. Baron de Larrey, a French army surgeon during Napoleon's Russian campaign, packed the limbs in ice prior to ampu...

    journal_title:Acta neurochirurgica

    pub_type: 历史文章,杂志文章

    doi:10.1007/s00701-006-0747-z

    authors: Wang H,Olivero W,Wang D,Lanzino G

    更新日期:2006-05-01 00:00:00

  • Dexamethasone inhibits ICAM-1 and MMP-9 expression and reduces brain edema in intracerebral hemorrhagic rats.

    abstract:BACKGROUND:The molecular mechanism of hemorrhagic stroke is unclear, and the identification of therapeutic agents for attenuating post-stroke brain damage remains an unresolved challenge. Dexamethasone (DEX) is used clinically to treat spinal cord injury and brain tumor patients by reducing edema formation, but has pro...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-011-1122-2

    authors: Yang JT,Lee TH,Lee IN,Chung CY,Kuo CH,Weng HH

    更新日期:2011-11-01 00:00:00

  • Asymmetry of tonsillar ectopia, syringomyelia and clinical manifestations in adult Chiari I malformation.

    abstract:BACKGROUND:The asymmetry of tonsillar ectopia, syringomyelia, and clinical manifestations, and their correlations in adult Chiari I malformation (CIM) are seldom discussed. METHODS:Clinical and imaging data of 104 consecutive adult patients with CIM and syringomyelia were retrospectively reviewed. A method was devised...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-014-2000-5

    authors: Deng X,Wang K,Wu L,Yang C,Yang T,Zhao L,Xu Y

    更新日期:2014-04-01 00:00:00

  • The lateral microsurgical approach to the "extracanalicular" lumbar disc herniation. I: A technical note.

    abstract::The main aim in the surgery of the canalicular and extracanalicular lumbar disc herniation is to remove safely the hidden fragment without complete destruction of the normal facet joint, without damage to the nerve root and with minimal compromise of the stability of the spinal column. This report describes a lateral ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01456353

    authors: Reulen HJ,Pfaundler S,Ebeling U

    更新日期:1987-01-01 00:00:00

  • Perfusion brain SPECT in assessing motor improvement after deep brain stimulation in Parkinson's disease.

    abstract:BACKGROUND:High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an established therapeutic approach for the management of patients with late-stage idiopathic Parkinson's disease (PD). The aim of the present study was to assess regional cerebral blood flow (rCBF) changes related to mot...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-012-1610-z

    authors: Paschali A,Constantoyannis C,Angelatou F,Vassilakos P

    更新日期:2013-03-01 00:00:00

  • [Postoperative vasospasm after clipping of intracranial aneurysms (author's transl)].

    abstract::After clipping of intracranial aneurysms, postoperative vasospasm may occur remote from the distribution area of the artery and may cause death. The authors report two cases and give the clinical, neuroradiological, and neuroanatomical findings. ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01773115

    authors: Kirchner M

    更新日期:1978-01-01 00:00:00

  • COXIBRAIN: results of the prospective, randomised, phase II/III study for the selective COX-2 inhibition in chronic subdural haematoma patients.

    abstract:BACKGROUND:Chronic subdural haematomas (cSDHs) have shown an increasing incidence in an ageing population over the last 20 years, while unacceptable recurrence rates of up to 30 % persist. The recurrence rate of cSDH seems to be related to the excessive neoangiogenesis in the parietal membrane, which is mediated via va...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00701-016-2949-3

    authors: Schaumann A,Klene W,Rosenstengel C,Ringel F,Tüttenberg J,Vajkoczy P

    更新日期:2016-11-01 00:00:00

  • Gross total resection of pituitary adenomas after endoscopic vs. microscopic transsphenoidal surgery: a meta-analysis.

    abstract:BACKGROUND:Microscopic transsphenoidal surgery (mTSS) is a well-established method to address adenomas of the pituitary gland. Endoscopic transsphenoidal surgery (eTSS) has become a viable alternative, however. Advocates suggest that the greater illumination, panoramic visualization, and angled endoscopic views afforde...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00701-017-3438-z

    authors: Almutairi RD,Muskens IS,Cote DJ,Dijkman MD,Kavouridis VK,Crocker E,Ghazawi K,Broekman MLD,Smith TR,Mekary RA,Zaidi HA

    更新日期:2018-05-01 00:00:00

  • The medial safe zone for treating intraneural ganglion cysts in the tarsal tunnel: a technical note.

    abstract:INTRODUCTION:Intraneural ganglion cysts in the tarsal tunnel are rare but are being increasingly reported. The cysts involve the tibial or plantar nerves and are most commonly derived from a neighboring (degenerative) joint, (i.e., the tibiotalar or subtalar) via an articular branch arising from the medial aspect of th...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-019-04027-8

    authors: Puffer RC,Spinner RJ

    更新日期:2019-10-01 00:00:00

  • What is the cause of post-traumatic stress disorder following subarachnoid haemorrhage? Post-ictal events are key.

    abstract:BACKGROUND:Post-traumatic stress disorder (PTSD) is common after subarachnoid haemorrhage (SAH) and causes poor outcome. Knowing which SAH events cause the stress leading to PTSD development could allow for their severity, and so the chances of PTSD, to be reduced. The dramatic nature of SAH onset has meant ictal event...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-010-0843-y

    authors: Baisch SB,Schenk T,Noble AJ

    更新日期:2011-04-01 00:00:00

  • Repair of damaged cortical artery by direct micro-suture in surgical treatment of acute subdural hematoma: technical note.

    abstract:BACKGROUND:In surgical treatment of acute subdural hematoma (ASDH), neurosurgeons frequently encounter bleeding from cortical arteries, which is usually controlled with bipolar coagulation. However, bipolar coagulation is associated with a risk of sacrificing the cortical artery, which may affect the prognosis of neuro...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-018-3634-5

    authors: Uneda A,Hirashita K,Yabuno S,Kanda T,Suzuki K,Matsumoto A,Yunoki M,Yoshino K

    更新日期:2018-10-01 00:00:00

  • Thallium-201 technetium-99m HMPAO single-photon emission computed tomography (SPECT) imaging for guiding stereotactic craniotomies in heavily irradiated malignant glioma patients.

    abstract::SPECT scanning with Tl-201 and Tc-99m offers a unique, inexpensive functional imaging modality to combine with CT stereotactic craniotomy for guiding resection of necrosis and/or tumour in patients treated with escalated doses of radiation (> 6000 cGy) by either brachytherapy or radiosurgery. Thirty-two cases were ana...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01405531

    authors: Alexander E 3rd,Loeffler JS,Schwartz RB,Johnson KA,Carvalho PA,Garada BM,Zimmerman RE,Holman BL

    更新日期:1993-01-01 00:00:00

  • The anterior pituitary lobe in patients with cystic craniopharyngiomas: three cases of associated lymphocytic hypophysitis.

    abstract::Specimens of the anterior pituitary lobe were investigated histologically in 28 craniopharyngioma patients operated on trans-sphenoidally. The pituitary glands in 3 patients revealed lymphocytic invasion giving a histological appearance typical of lymphocytic hypophysitis (incidence: 11%). At follow-up examination all...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01476492

    authors: Puchner MJ,Lüdecke DK,Saeger W

    更新日期:1994-01-01 00:00:00