Hyaloraphidium curvatum: a linear mitochondrial genome, tRNA editing, and an evolutionary link to lower fungi.

abstract：:Pseudogenes are nonfunctional relics of formerly functional genes and are thought to evolve neutrally. In some pseudogenes, however, the molecular evolutionary patterns are atypical of neutrally evolving sequences, exhibiting sequence conservation, codon-usage bias, and other features associated with functional genes....

journal_title：Molecular biology and evolution

authors： Podlaha O,Zhang J

更新日期：2004-12-01 00:00:00

abstract：:This study establishes a phylogenetic framework for the natural geographic isolates of the widely studied nematode species Caenorhabditis elegans. Virtually complete mitochondrial genomes are sequenced from 27 C. elegans natural isolates to characterize mitochondrial divergence patterns and to investigate the evolutio...

journal_title：Molecular biology and evolution

authors： Denver DR,Morris K,Thomas WK

更新日期：2003-03-01 00:00:00

abstract：:Complex metazoan bodies require cell-to-cell communication for development, a process often mediated by signaling molecules binding to specific receptors. Relatively few signaling pathways have been recruited during evolution to build multicellular animals from unicellular zygotes. Of these few signaling pathways, one...

journal_title：Molecular biology and evolution

authors： Bertrand S,Iwema T,Escriva H

更新日期：2014-02-01 00:00:00

abstract：:The evolution of DNA base composition evolution is simplified to a six-parameter model when there are no strand biases for mutation and selection. We analyzed the dynamics of this model with special attention to the influence of a change in substitution rates. The G + C content of the DNA sequence tends to an equilibr...

journal_title：Molecular biology and evolution

authors： Lobry JR,Lobry C

更新日期：1999-06-01 00:00:00

abstract：:Methods such as maximum parsimony (MP) are frequently criticized as being statistically unsound and not being based on any "model." On the other hand, advocates of MP claim that maximum likelihood (ML) has some fundamental problems. Here, we explore the connection between the different versions of MP and ML methods, p...

journal_title：Molecular biology and evolution

authors： Steel M,Penny D

更新日期：2000-06-01 00:00:00

abstract：:In numerous species, individual dispersal is restricted in space so that "continuous" populations evolve under isolation by distance. A method based on individual genotypes assuming a lattice population model was recently developed to estimate the product Dsigma2, where D is the population density and sigma2 is the av...

journal_title：Molecular biology and evolution

authors： Leblois R,Estoup A,Rousset F

更新日期：2003-04-01 00:00:00

abstract：:Deletion rates are thought to be important factors in determining the genome size of organisms in nature. Although it is indisputable that deletions, and thus deletion rates, affect genome size, it is unclear how, or indeed if, genome size is regulated via the deletion rate. Here, we employ a mathematical model to det...

journal_title：Molecular biology and evolution

authors： Pettersson ME,Kurland CG,Berg OG

更新日期：2009-06-01 00:00:00

abstract：:The little fire ant, Wasmannia auropunctata, displays a peculiar breeding system polymorphism. Classical haplo-diploid sexual reproduction between reproductive individuals occurs in some populations, whereas, in others, queens and males reproduce clonally. Workers are produced sexually and are sterile in both clonal a...

journal_title：Molecular biology and evolution

authors： Rey O,Loiseau A,Facon B,Foucaud J,Orivel J,Cornuet JM,Robert S,Dobigny G,Delabie JH,Mariano Cdos S,Estoup A

更新日期：2011-09-01 00:00:00

abstract：:Restriction site variations in nuclear ribosomal DNA (rDNA) spacers and mitochondrial DNA (mtDNA) were examined in several populations of mole rats with variable numbers of chromosomes, which represented the two superspecies Spalax leucodon (2n = 38, 54, or 62) and Spalax ehrenbergi (2n = 52, 54, 58, or 60). Sequence ...

journal_title：Molecular biology and evolution

authors： Suzuki H,Wakana S,Yonekawa H,Moriwaki K,Sakurai S,Nevo E

更新日期：1996-01-01 00:00:00

abstract：:Good phylogenetic trees are required to test hypotheses about evolutionary processes. We report four new avian mitochondrial genomes, which together with an improved method of phylogenetic analysis for vertebrate mt genomes give results for three questions in avian evolution. The new mt genomes are: magpie goose (Anse...

journal_title：Molecular biology and evolution

authors： Harrison GL,McLenachan PA,Phillips MJ,Slack KE,Cooper A,Penny D

更新日期：2004-06-01 00:00:00

abstract：:Identifying mechanisms that underlie variation in adult survivorship provide insight into the evolution of life history strategies and phenotypic variation in longevity. There is accumulating evidence that shortening telomeres, the protective caps at the ends of chromosomes, play an important role in individual variat...

journal_title：Molecular biology and evolution

authors： Haussmann MF,Mauck RA

更新日期：2008-01-01 00:00:00

abstract：:Amino acid substitution matrices describe the rates by which amino acids are replaced during evolution. In contrast to nucleotide or codon models, amino acid substitution matrices are in general parameterless and empirically estimated, probably because there is no obvious parametrization for amino acid substitutions. ...

journal_title：Molecular biology and evolution

authors： Zoller S,Schneider A

更新日期：2013-02-01 00:00:00

abstract：:The diversity and evolution of bitter taste perception in mammals is not well understood. Recent discoveries of bitter taste receptor (T2R) genes provide an opportunity for a genetic approach to this question. We here report the identification of 10 and 30 putative T2R genes from the draft human and mouse genome seque...

journal_title：Molecular biology and evolution

authors： Shi P,Zhang J,Yang H,Zhang YP

更新日期：2003-05-01 00:00:00

abstract：:This study aims to unravel the biogeography of a model symbiont/host system by exploiting the prediction that a symbiont will leave a signature of infection on the host. Specifically, a global sample of 1,442 Drosophila simulans from 33 countries and 64 sampling localities was employed to infer the phylogeography of t...

journal_title：Molecular biology and evolution

authors： Ballard JW

更新日期：2004-03-01 00:00:00

abstract：:The third chromosome of Drosophila pseudoobscura is polymorphic for numerous gene arrangements that form classical clines in North America. The polytene salivary chromosomes isolated from natural populations revealed changes in gene order that allowed the different gene arrangements to be linked together by paracentri...

journal_title：Molecular biology and evolution

authors： Wallace AG,Detweiler D,Schaeffer SW

更新日期：2011-08-01 00:00:00

abstract：:Thyroid hormones are involved in the regulation of growth and metabolism in all vertebrates. Transthyretin is one of the extracellular proteins with high affinity for thyroid hormones which determine the partitioning of these hormones between extracellular compartments and intracellular lipids. During vertebrate evolu...

journal_title：Molecular biology and evolution

authors： Prapunpoj P,Richardson SJ,Fumagalli L,Schreiber G

更新日期：2000-08-01 00:00:00

abstract：:Hybridization is often considered maladaptive, but sometimes hybrids can invade new ecological niches and adapt to novel or stressful environments better than their parents. The genomic changes that occur following hybridization that facilitate genome resolution and/or adaptation are not well understood. Here, we exam...

journal_title：Molecular biology and evolution

authors： Smukowski Heil CS,DeSevo CG,Pai DA,Tucker CM,Hoang ML,Dunham MJ

更新日期：2017-07-01 00:00:00

abstract：:Spinocerebellar ataxia type 10 is caused by ATTCT repeat expansion in the ATXN10 gene in humans. We studied the evolutionary history of the human genome to determine the time and mechanism of the acquisition of unstable ATTCT repeats in the genome. We found that long interspersed element-1 (LINE-1) was inserted into A...

journal_title：Molecular biology and evolution

authors： Kurosaki T,Matsuura T,Ohno K,Ueda S

更新日期：2009-11-01 00:00:00

abstract：:Here we report the peculiarities of molecular evolution and divergence of paralogous heterochromatic clusters of the testis- expressed X-linked Stellate and Y-linked Su(Ste) tandem repeats. It was suggested that Stellate and Su(Ste) clusters affecting male fertility are the amplified derivatives of the unique euchroma...

journal_title：Molecular biology and evolution

authors： Kogan GL,Epstein VN,Aravin AA,Gvozdev VA

更新日期：2000-05-01 00:00:00

abstract：:Much of evolutionary change is mediated at the level of gene expression, yet our understanding of regulatory evolution remains unsatisfying. In light of recent data indicating that transcription factor binding sites undergo substantial turnover between species, we attempt to quantify the process of binding site turnov...

journal_title：Molecular biology and evolution

authors： Dermitzakis ET,Bergman CM,Clark AG

更新日期：2003-05-01 00:00:00

abstract：:Despite the general assumption that site-specific mutation rates are independent of the local sequence context, a growing body of evidence suggests otherwise. To further examine context-dependent patterns of mutation, we amassed 5,645 spontaneous mutations in wild- type (WT) and mismatch-repair deficient (MMR(-)) muta...

journal_title：Molecular biology and evolution

authors： Sung W,Ackerman MS,Gout JF,Miller SF,Williams E,Foster PL,Lynch M

更新日期：2015-07-01 00:00:00

abstract：:Proteomic analyses of the nucleolus have revealed almost 700 functionally diverse proteins implicated in ribosome biogenesis, nucleolar assembly, and regulation of vital cellular processes. However, this nucleolar inventory has not unveiled a specific consensus motif necessary for nucleolar binding. The ribosomal prot...

journal_title：Molecular biology and evolution

authors： Kundu-Michalik S,Bisotti MA,Lipsius E,Bauche A,Kruppa A,Klokow T,Kammler G,Kruppa J

更新日期：2008-03-01 00:00:00

abstract：:A more than 10-fold difference in the specificity and catalytic efficiency for 1-naphthyl esters was measured between two allozymes of esterase-4 from Drosophila mojavensis. This difference is mainly caused by a difference in the affinity for the 1-naphthyl esters. The amino acid compositions of the allozymes are not ...

journal_title：Molecular biology and evolution

authors： Pen J,Schipper A,Rongen HA,Beintema JJ

更新日期：1986-07-01 00:00:00

abstract：:Snake venom gene evolution has been studied intensively over the past several decades, yet most previous studies have lacked the context of complete snake genomes and the full context of gene expression across diverse snake tissues. We took a novel approach to studying snake venom evolution by leveraging the complete ...

journal_title：Molecular biology and evolution

authors： Reyes-Velasco J,Card DC,Andrew AL,Shaney KJ,Adams RH,Schield DR,Casewell NR,Mackessy SP,Castoe TA

更新日期：2015-01-01 00:00:00

abstract：:Long INterspersed Elements-1 (L1s) constitute >17% of the human genome and still actively transpose in it. Characterizing L1 transposition across the genome is critical for understanding genome evolution and somatic mutations. However, to date, L1 insertion and fixation patterns have not been studied comprehensively. ...

journal_title：Molecular biology and evolution

authors： Chen D,Cremona MA,Qi Z,Mitra RD,Chiaromonte F,Makova KD

更新日期：2020-12-16 00:00:00

abstract：:Ion channels have played a substantial role in the evolution of novel traits across all of the domains of life. A fascinating example of a novel adaptation is the convergent evolution of electric organs in the Mormyroid and Gymnotiform electric fishes. The regulated currents that flow through ion channels directly gen...

journal_title：Molecular biology and evolution

authors： Thompson A,Vo D,Comfort C,Zakon HH

更新日期：2014-08-01 00:00:00

abstract：:Parasitoid wasps use venom to manipulate the immunity and metabolism of their host insects in a variety of ways to provide resources for their offspring. Yet, how genes are recruited and evolve to perform venom functions remain open questions. A recently recognized source of eukaryotic genome innovation is lateral gen...

journal_title：Molecular biology and evolution

authors： Martinson EO,Martinson VG,Edwards R,Mrinalini,Werren JH

更新日期：2016-04-01 00:00:00

abstract：:Measuring natural selection on genomic elements involved in the cis-regulation of gene expression--such as transcriptional enhancers and promoters--is critical for understanding the evolution of genomes, yet it remains a major challenge. Many studies have attempted to detect positive or negative selection in these non...

journal_title：Molecular biology and evolution

authors： Smith JD,McManus KF,Fraser HB

更新日期：2013-11-01 00:00:00

abstract：:Protamines are small, highly basic DNA-binding proteins found in the sperm of animals. Interestingly, the proportion of arginine residues in one type of protamine, protamine P1, is about 50% in mammals. Upon closer examination, it was found that both the total number of amino acids and the positions of arginine residu...

journal_title：Molecular biology and evolution

authors： Rooney AP,Zhang J,Nei M

更新日期：2000-02-01 00:00:00

abstract：:Here, we present a study of the molecular evolution of the pheromone receptor genes (pre-1 and pre-2) in Neurospora taxa with different mating systems. We focus on comparisons between heterothallic and homothallic taxa, reproducing sexually by outcrossing and by intrahaploid selfing, respectively. Our general aim was ...

journal_title：Molecular biology and evolution

authors： Nygren K,Strandberg R,Gioti A,Karlsson M,Johannesson H

更新日期：2012-12-01 00:00:00