Sequential evolution of a symbiont inferred from the host: Wolbachia and Drosophila simulans.

abstract：:In termites, as in many social insects, some individuals specialize in colony defense, developing diverse weaponry. As workers of the termite Neocapritermes taracua (Termitidae: Termitinae) age, their efficiency to perform general tasks decreases, while they accumulate defensive secretions and increase their readiness...

journal_title：Molecular biology and evolution

authors： Bourguignon T,Šobotník J,Brabcová J,Sillam-Dussès D,Buček A,Krasulová J,Vytisková B,Demianová Z,Mareš M,Roisin Y,Vogel H

更新日期：2016-03-01 00:00:00

abstract：:Due to its speed, the distance approach remains the best hope for building phylogenies on very large sets of taxa. Recently (R. Desper and O. Gascuel, J. Comp. Biol. 9:687-705, 2002), we introduced a new "balanced" minimum evolution (BME) principle, based on a branch length estimation scheme of Y. Pauplin (J. Mol. Evo...

journal_title：Molecular biology and evolution

authors： Desper R,Gascuel O

更新日期：2004-03-01 00:00:00

abstract：:Ever since Luria and Delbruck, the notion that mutation is random with respect to fitness has been foundational to modern biology. However, various studies have claimed striking exceptions to this rule. One influential case involves toxin-encoding genes in snails of the genus Conus, termed conotoxins, a large gene fam...

journal_title：Molecular biology and evolution

authors： Roy SW

更新日期：2016-10-01 00:00:00

abstract：:To investigate the potential importance of gene duplication in D. melanogaster accessory gland protein (Acp) gene evolution we carried out a computational analysis comparing annotated D. melanogaster Acp genes to the entire D. melanogaster genome. We found that two known Acp genes are actually members of small multige...

journal_title：Molecular biology and evolution

authors： Holloway AK,Begun DJ

更新日期：2004-09-01 00:00:00

abstract：:Male reproductive fitness is strongly affected by seminal fluid. In addition to interacting with the female environment, seminal fluid mediates important physiological characteristics of sperm, including capacitation and motility. In mammals, the male reproductive tract shows a striking degree of compartmentalization,...

journal_title：Molecular biology and evolution

authors： Dean MD,Clark NL,Findlay GD,Karn RC,Yi X,Swanson WJ,MacCoss MJ,Nachman MW

更新日期：2009-08-01 00:00:00

abstract：:Enzyme function is strongly affected by temperature, and orthologs from species adapted to different thermal environments often show temperature compensation in kinetic properties. Antarctic notothenioid fishes live in a habitat of constant, extreme cold (-1.86 +/- 2 degrees C), and orthologs of the enzyme A4-lactate ...

journal_title：Molecular biology and evolution

authors： Fields PA,Houseman DE

更新日期：2004-12-01 00:00:00

abstract：:We investigated diverse genomic selections using high-density single nucleotide polymorphism data of five distinct cattle breeds. Based on allele frequency differences, we detected hundreds of candidate regions under positive selection across Holstein, Angus, Charolais, Brahman, and N'Dama. In addition to well-known g...

journal_title：Molecular biology and evolution

authors： Xu L,Bickhart DM,Cole JB,Schroeder SG,Song J,Tassell CP,Sonstegard TS,Liu GE

更新日期：2015-03-01 00:00:00

abstract：:Polygalacturonase inhibitor proteins (PGIPs) protect plants against invasion by diverse microbial and invertebrate enemies that use polygalacturonase (PG) to breach the plant cell wall. Directed mutagenesis has identified specific natural mutations conferring novel defensive capability in green bean PGIP against a spe...

journal_title：Molecular biology and evolution

authors： Bishop JG

更新日期：2005-07-01 00:00:00

abstract：:The serial coalescent extends traditional coalescent theory to include genealogies in which not all individuals were sampled at the same time. Inference in this framework is powerful because population size and evolutionary rate may be estimated independently. However, when the sequences in question are affected by se...

journal_title：Molecular biology and evolution

authors： O'Fallon BD

更新日期：2011-11-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) do not code for proteins but function as RNAs. Because the functions of an RNA rely on either its sequence or secondary structure, lncRNAs should be folded at least as strongly as messenger RNAs (mRNAs), which serve as messengers for translation and are generally thought to lack secondary...

journal_title：Molecular biology and evolution

authors： Yang JR,Zhang J

更新日期：2015-04-01 00:00:00

abstract：:The environment has profound effects on the expression of many traits and reaction norms describe the expression dynamics of a trait across a broad range of environmental conditions. Here, we analyze gene expression in Drosophila melanogaster across four different developmental temperatures (13-29 °C). Gene expression...

journal_title：Molecular biology and evolution

authors： Chen J,Nolte V,Schlötterer C

更新日期：2015-09-01 00:00:00

abstract：:Chemosensory genes are frequently the target of positive selection and are often present in large gene families, but little is known about heterogeneity of selection in these cases and its relation to function. Here, we use the vomeronasal-1 receptor (V1R) repertoire of mouse lemurs (Microcebus spp.) as a model system...

journal_title：Molecular biology and evolution

authors： Hohenbrink P,Radespiel U,Mundy NI

更新日期：2012-12-01 00:00:00

abstract：:Mouse has emerged as the most common model organism in biomedicine. Here, we analyzed the tolerance to the loss-of-function (LoF) of selenoprotein genes, estimated from mouse knockouts and the frequency of LoF variants in humans. We found not only a general correspondence in tolerance (e.g., GPX1, GPX2) and intoleranc...

journal_title：Molecular biology and evolution

authors： Santesmasses D,Mariotti M,Gladyshev VN

更新日期：2020-02-01 00:00:00

abstract：:Current data on green algal mitochondrial genomes suggest an unexpected dichotomy within the group with respect to genome structure, organization, and sequence affiliations. The present study suggests that there is a correlation between this dichotomy on one hand and the differences in the abundance, base composition,...

journal_title：Molecular biology and evolution

authors： Nedelcu AM,Lee RW

更新日期：1998-06-01 00:00:00

abstract：:A 32-kb region including the Adh structural gene was analyzed with six restriction endonucleases in 20 lines of Drosophila pseudoobscura, one line of D. persimilis, and one line of D. miranda. Nineteen lines of D. pseudoobscura from a single population were estimated to be polymorphic at one in every 15 nucleotides (p...

journal_title：Molecular biology and evolution

authors： Schaeffer SW,Aquadro CF,Anderson WW

更新日期：1987-05-01 00:00:00

abstract：:We present the first molecular phylogenetic examination of the evolutionary position of retortamonads, a group of mitochondrion-lacking flagellates usually found as commensals of the intestinal tracts of vertebrates. Our phylogenies include small subunit ribosomal gene sequences from six retortamonad isolates-four fro...

journal_title：Molecular biology and evolution

authors： Silberman JD,Simpson AG,Kulda J,Cepicka I,Hampl V,Johnson PJ,Roger AJ

更新日期：2002-05-01 00:00:00

abstract：:Phylogenetic reconstruction of the evolutionary history of closely related organisms may be difficult because of the presence of unsorted lineages and of a relatively high proportion of heterozygous sites that are usually not handled well by phylogenetic programs. Genomic data may provide enough fixed polymorphisms to...

journal_title：Molecular biology and evolution

authors： Lischer HE,Excoffier L,Heckel G

更新日期：2014-04-01 00:00:00

abstract：:In a striking contrast, matK is one of the most rapidly evolving plastid genes and also one of the few plastid genes to be retained in all nonphotosynthetic plants examined to date. DNA sequences of this region were obtained from photosynthetic and nonphotosynthetic plants of Orobanchaceae and their relatives. The res...

journal_title：Molecular biology and evolution

authors： Young ND,dePamphilis CW

更新日期：2000-12-01 00:00:00

abstract：:The evolution of mitochondria from ancestral bacteria required that new protein transport machinery be established. Recent controversy over the evolution of these new molecular machines hinges on the degree to which ancestral bacterial transporters contributed during the establishment of the new protein import pathway...

journal_title：Molecular biology and evolution

authors： Tong J,Dolezal P,Selkrig J,Crawford S,Simpson AG,Noinaj N,Buchanan SK,Gabriel K,Lithgow T

更新日期：2011-05-01 00:00:00

abstract：:Heuristic approaches were used to quantify the influence that sequencing errors have on estimates of nucleotide diversity, substitution rate, and the construction of genealogies. Error rates of less than 1 nucleotide/kb probably have little affect on conclusions about the evolutionary history of highly polymorphic org...

journal_title：Molecular biology and evolution

authors： Clark AG,Whittam TS

更新日期：1992-07-01 00:00:00

abstract：:Effective population size is fundamental in population genetics and characterizes genetic diversity. To infer past population dynamics from molecular sequence data, coalescent-based models have been developed for Bayesian nonparametric estimation of effective population size over time. Among the most successful is a G...

journal_title：Molecular biology and evolution

authors： Gill MS,Lemey P,Faria NR,Rambaut A,Shapiro B,Suchard MA

更新日期：2013-03-01 00:00:00

abstract：:Current phylogenetic tree reconstruction methods assume that there is a single underlying tree topology for all sites along the sequence. The presence of mosaic sequences due to recombination violates this assumption and will cause phylogenetic methods to give misleading results due to the imposition of a single tree ...

journal_title：Molecular biology and evolution

authors： McGuire G,Wright F,Prentice MJ

更新日期：1997-11-01 00:00:00

abstract：:Phenotypic convergence is an exciting outcome of adaptive evolution, occurring when different species find similar solutions to the same problem. Unraveling the molecular basis of convergence provides a way to link genotype to adaptive phenotypes, but can also shed light on the extent to which molecular evolution is r...

journal_title：Molecular biology and evolution

authors： Mendes FK,Hahn Y,Hahn MW

更新日期：2016-12-01 00:00:00

abstract：:Human DNA variation is currently a subject of intense research because of its importance for studying human origins, evolution, and demographic history and for association studies of complex diseases. A approximately 10-kb region on chromosome 1, which contains only four small exons (each <155 bp), was sequenced for 6...

journal_title：Molecular biology and evolution

authors： Yu N,Zhao Z,Fu YX,Sambuughin N,Ramsay M,Jenkins T,Leskinen E,Patthy L,Jorde LB,Kuromori T,Li WH

更新日期：2001-02-01 00:00:00

abstract：:Although evolutionary studies of gene function often rely on RNA interference, the ideal approach would use reverse genetics to create null mutations for cross-species comparisons and forward genetics to identify novel genes in each species. We have used transcription activator-like effector nucleases (TALENs) to faci...

journal_title：Molecular biology and evolution

authors： Wei Q,Shen Y,Chen X,Shifman Y,Ellis RE

更新日期：2014-02-01 00:00:00

abstract：:To test whether gaps resulting from sequence alignment contain phylogenetic signal concordant with those of base substitutions, we analyzed the occurrence of indel mutations upon a well-resolved, substitution-based tree for three nuclear genes in bumble bees (Bombus, Apidae: Bombini). The regions analyzed were exon an...

journal_title：Molecular biology and evolution

authors： Kawakita A,Sota T,Ascher JS,Ito M,Tanaka H,Kato M

更新日期：2003-01-01 00:00:00

abstract：:Males and females often have marked phenotypic differences, and the expression of these dissimilarities invariably involves sex differences in gene expression. Sex-biased gene expression has been well characterized in animal species, where a high proportion of the genome may be differentially regulated in males and fe...

journal_title：Molecular biology and evolution

authors： Lipinska A,Cormier A,Luthringer R,Peters AF,Corre E,Gachon CM,Cock JM,Coelho SM

更新日期：2015-06-01 00:00:00

abstract：:Statistical methods for computing the standard errors of the branching points of an evolutionary tree are developed. These methods are for the unweighted pair-group method-determined (UPGMA) trees reconstructed from molecular data such as amino acid sequences, nucleotide sequences, restriction-sites data, and electrop...

journal_title：Molecular biology and evolution

authors： Nei M,Stephens JC,Saitou N

更新日期：1985-01-01 00:00:00

abstract：:A recent study conducted the first genome-wide scan for selection in Inuit from Greenland using single nucleotide polymorphism chip data. Here, we report that selection in the region with the second most extreme signal of positive selection in Greenlandic Inuit favored a deeply divergent haplotype that is closely rela...

journal_title：Molecular biology and evolution

authors： Racimo F,Gokhman D,Fumagalli M,Ko A,Hansen T,Moltke I,Albrechtsen A,Carmel L,Huerta-Sánchez E,Nielsen R

更新日期：2017-03-01 00:00:00

abstract：:Dogs exhibit more phenotypic variation than any other mammal and are affected by a wide variety of genetic diseases. However, the origin and genetic basis of this variation is still poorly understood. We examined the effect of domestication on the dog genome by comparison with its wild ancestor, the gray wolf. We comp...

journal_title：Molecular biology and evolution

authors： Cruz F,Vilà C,Webster MT

更新日期：2008-11-01 00:00:00