An organic psychosis due to a venlafaxine-propafenone interaction.

Abstract:

OBJECTIVE:An extraordinary case of an organic psychosis during the treatment of a patient with a bipolar affective disorder. METHODS:Clinical observation and further investigations including monitoring of serum levels (case report). RESULTS:A significant interaction between venlafaxine and propafenone causes markedly increased serum levels of venlafaxine correlating with unexpected psychopathological changes. CONCLUSIONS:There is a potentially dangerous interaction between venlafaxine and propafenone. Serum levels of venlafaxine should be monitored if propafenone is added.

journal_name

Int J Psychiatry Med

authors

Pfeffer F,Grube M

doi

10.2190/8HJA-LPRY-P16X-BH8U

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

427-32

issue

4

eissn

0091-2174

issn

1541-3527

journal_volume

31

pub_type

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