Mitochondrial genome of the colorless green alga Polytomella parva: two linear DNA molecules with homologous inverted repeat Termini.

abstract：:Evolution of sequences mostly involves independent changes at different sites. However, substitutions at neighboring sites may co-occur as multinucleotide replacement events (MNRs). Here, we compare noncoding sequences of several species of primates, and of three species of Drosophila fruit flies, in a phylogenetic an...

journal_title：Molecular biology and evolution

authors： Terekhanova NV,Bazykin GA,Neverov A,Kondrashov AS,Seplyarskiy VB

更新日期：2013-06-01 00:00:00

abstract：:The evolutionary expansion of CAG repeats in human triplet expansion disease genes is intriguing because of their deleterious phenotype. In the past, this expansion has been suggested to reflect a broad genomewide expansion of repeats, which would imply that mutational and evolutionary processes acting on repeats diff...

journal_title：Molecular biology and evolution

authors： Hancock JM,Worthey EA,Santibáñez-Koref MF

更新日期：2001-06-01 00:00:00

abstract：:In a series of highly influential publications, Cavalli-Sforza and colleagues used principal component (PC) analysis to produce maps depicting how human genetic diversity varies across geographic space. Within Europe, the first axis of variation (PC1) was interpreted as evidence for the demic diffusion model of agricu...

journal_title：Molecular biology and evolution

authors： François O,Currat M,Ray N,Han E,Excoffier L,Novembre J

更新日期：2010-06-01 00:00:00

abstract：:A major topic of interest in human prehistory is how the large-scale genetic structure of modern populations outside of Africa was established. Demographic models have been developed that capture the relationships among small numbers of populations or within particular geographical regions, but constructing a phylogen...

journal_title：Molecular biology and evolution

authors： Lipson M,Reich D

更新日期：2017-04-01 00:00:00

abstract：:A highly abundant satellite DNA comprising 17% of the Tribolium castaneum (Insecta, Coleoptera) genome was cloned and sequenced. The satellite monomer is 360 bp long, has a high A+T content of 73%, and lacks significant internal substructures. The sequence variability is 3.6%, essentially due to random distribution of...

journal_title：Molecular biology and evolution

authors： Ugarković D,Podnar M,Plohl M

更新日期：1996-10-01 00:00:00

abstract：:A phylogenetic tree of a gene family of nicotinic acetylcholine receptor subunits was constructed using 84 nucleotide sequences of receptor subunits from 18 different species in order to elucidate the evolutionary origin of receptor subunits. The tree constructed showed that the common ancestor of all subunits may hav...

journal_title：Molecular biology and evolution

authors： Tsunoyama K,Gojobori T

更新日期：1998-05-01 00:00:00

abstract：:The brine shrimp Artemia has three extracellular hemoglobins (Hbs) that are developmentally expressed and exhibit distinct oxygen-binding characteristics (Heip, Moens, and Kondo 1978; Heip et al. 1978 ). These Hbs are composed of two polymers, each of which comprises nine covalently linked globin domains. Although the...

journal_title：Molecular biology and evolution

authors： Vandenberg CJ,Matthews CM,Trotman CN

更新日期：2002-08-01 00:00:00

abstract：:We report a major update of the MAFFT multiple sequence alignment program. This version has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the...

journal_title：Molecular biology and evolution

authors： Katoh K,Standley DM

更新日期：2013-04-01 00:00:00

abstract：:Despite its poorly adapted codon usage, HIV-1 replicates and is expressed extremely well in human host cells. HIV-1 has recently been shown to package non-lysyl transfer RNAs (tRNAs) in addition to the tRNA(Lys) needed for priming reverse transcription and integration of the HIV-1 genome. By comparing the codon usage ...

journal_title：Molecular biology and evolution

authors： van Weringh A,Ragonnet-Cronin M,Pranckeviciene E,Pavon-Eternod M,Kleiman L,Xia X

更新日期：2011-06-01 00:00:00

abstract：:Sex-biased gene expression is becoming an increasingly important way to study sexual selection at the molecular genetic level. However, little is known about the timing, persistence, and continuity of gene expression required in the creation of distinct male and female phenotypes, and even less about how sex-specific ...

journal_title：Molecular biology and evolution

authors： Mank JE,Nam K,Brunström B,Ellegren H

更新日期：2010-07-01 00:00:00

abstract：:Cytochrome c oxidase (COX) consists of 13 subunits, 3 encoded in the mitochondrial genome and 10 in the nucleus. Little is known of the role of the nuclear-encoded subunits, some of which exhibit tissue-specific isoforms. Subunit VIa is unique in having tissue-specific isoforms in all mammalian species examined. We ex...

journal_title：Molecular biology and evolution

authors： Schmidt TR,Jaradat SA,Goodman M,Lomax MI,Grossman LI

更新日期：1997-06-01 00:00:00

abstract：:The high frequency of alternative splicing among the serine/arginine-rich (SR) family of proteins in plants has been linked to important roles in gene regulation during development and in response to environmental stress. In this article, we have searched and manually annotated all the SR proteins in the genomes of ma...

journal_title：Molecular biology and evolution

authors： Rauch HB,Patrick TL,Klusman KM,Battistuzzi FU,Mei W,Brendel VP,Lal SK

更新日期：2014-03-01 00:00:00

abstract：:The organization of the mitochondrial genome is generally very conserved among vertebrates. Because of this, examination of the rare rearrangements which do occur has been suggested as offering a powerful alternative to phylogenetic analyses of mitochondrial DNA sequences. Here, we report on an avian mitochondrial rea...

journal_title：Molecular biology and evolution

authors： Bensch S,Härlid A

更新日期：2000-01-01 00:00:00

abstract：:Spinocerebellar ataxia type 10 is caused by ATTCT repeat expansion in the ATXN10 gene in humans. We studied the evolutionary history of the human genome to determine the time and mechanism of the acquisition of unstable ATTCT repeats in the genome. We found that long interspersed element-1 (LINE-1) was inserted into A...

journal_title：Molecular biology and evolution

authors： Kurosaki T,Matsuura T,Ohno K,Ueda S

更新日期：2009-11-01 00:00:00

abstract：:A sample of the second largest subunit of low-copy nuclear RNA polymerase II (rpb2) sequences from Malvaceae subfamily Malvoideae suggests that rpb2 has been duplicated early in the subfamily's history. Hibiscus and related taxa possess two rpb2 genes, both of which produce congruent phylogenetic patterns that are lar...

journal_title：Molecular biology and evolution

authors： Pfeil BE,Brubaker CL,Craven LA,Crisp MD

更新日期：2004-07-01 00:00:00

abstract：:Direct sequencing of polymerase chain reaction products is now an expanding area of plant systematics and evolution. Within angiosperms the rbcL gene has been widely sequenced and used for inferring plant phylogenies at higher taxonomic levels. Unfortunately rbcL does not usually contain enough information to resolve ...

journal_title：Molecular biology and evolution

authors： Gielly L,Taberlet P

更新日期：1994-09-01 00:00:00

abstract：:Full-length mariner-like elements (MLEs) were identified from both a parasitoid wasp, Ascogaster reticulatus, and its moth host, Adoxophyes honmai. MLEs were detected in two related Tortricid moths, but not in another Ascogaster species. The MLEs of A. reticulatus and A. honmai were 97.6% identical in DNA sequence. Th...

journal_title：Molecular biology and evolution

authors： Yoshiyama M,Tu Z,Kainoh Y,Honda H,Shono T,Kimura K

更新日期：2001-10-01 00:00:00

abstract：:Models of codon evolution have attracted particular interest because of their unique capabilities to detect selection forces and their high fit when applied to sequence evolution. We described here a novel approach for modeling codon evolution, which is based on Kronecker product of matrices. The 61 × 61 codon substit...

journal_title：Molecular biology and evolution

authors： Zaheri M,Dib L,Salamin N

更新日期：2014-09-01 00:00:00

abstract：:The diversity of color vision systems found in extant vertebrates suggests that different evolutionary selection pressures have driven specializations in photoreceptor complement and visual pigment spectral tuning appropriate for an animal's behavior, habitat, and life history. Aquatic vertebrates in particular show h...

journal_title：Molecular biology and evolution

authors： Hart NS,Lamb TD,Patel HR,Chuah A,Natoli RC,Hudson NJ,Cutmore SC,Davies WIL,Collin SP,Hunt DM

更新日期：2020-03-01 00:00:00

abstract：:IQ-TREE (http://www.iqtree.org, last accessed February 6, 2020) is a user-friendly and widely used software package for phylogenetic inference using maximum likelihood. Since the release of version 1 in 2014, we have continuously expanded IQ-TREE to integrate a plethora of new models of sequence evolution and efficien...

journal_title：Molecular biology and evolution

authors： Minh BQ,Schmidt HA,Chernomor O,Schrempf D,Woodhams MD,von Haeseler A,Lanfear R

更新日期：2020-05-01 00:00:00

abstract：:Spatial distribution and clustering of repetitive elements are extensively studied during the last years, as well as their colocalization with other genomic components. Here we investigate the large-scale features of Alu and LINE1 spatial arrangement in the human genome by studying the size distribution of interrepeat...

journal_title：Molecular biology and evolution

authors： Sellis D,Provata A,Almirantis Y

更新日期：2007-11-01 00:00:00

abstract：:The structural genes for nitrogenase, nifK, nifD, and nifH, are crucial for nitrogen fixation. Previous phylogenetic analysis of the amino acid sequence of nifH suggested that this gene had been horizontally transferred from a proteobacterium to the gram-positive/cyanobacterial clade, although the confounding effects ...

journal_title：Molecular biology and evolution

authors： Hirsch AM,McKhann HI,Reddy A,Liao J,Fang Y,Marshall CR

更新日期：1995-01-01 00:00:00

abstract：:The assumption of a molecular clock for dating events from sequence information is often frustrated by the presence of heterogeneity among evolutionary rates due, among other factors, to positively selected sites. In this work, our goal is to explore methods to estimate infection dates from sequence analysis. One such...

journal_title：Molecular biology and evolution

authors： Wróbel B,Torres-Puente M,Jiménez N,Bracho MA,García-Robles I,Moya A,González-Candelas F

更新日期：2006-06-01 00:00:00

abstract：:The genes of tryptophan biosynthesis are arranged and regulated differently in many microorganisms. Comparison of the transcription regulatory regions of the trp operons of several species of enterobacteria reveals that those sequences and structures believed to be essential for repression and attenuation control are ...

journal_title：Molecular biology and evolution

authors： Yanofsky C

更新日期：1984-02-01 00:00:00

abstract：:Malaria is a deadly disease that causes nearly one million deaths each year. To develop methods to control and eradicate malaria, it is important to understand the genetic basis of Plasmodium falciparum adaptations to antimalarial treatments and the human immune system while taking into account its demographic history...

journal_title：Molecular biology and evolution

authors： Chang HH,Park DJ,Galinsky KJ,Schaffner SF,Ndiaye D,Ndir O,Mboup S,Wiegand RC,Volkman SK,Sabeti PC,Wirth DF,Neafsey DE,Hartl DL

更新日期：2012-11-01 00:00:00

abstract：:The role of adaptation in the divergence of lineages has long been a central question in evolutionary biology, and as multilocus sequence data sets have become available for a wide range of taxa, empirical estimates of levels of adaptive molecular evolution are increasingly common. Estimates vary widely among taxa, wi...

journal_title：Molecular biology and evolution

authors： Strasburg JL,Kane NC,Raduski AR,Bonin A,Michelmore R,Rieseberg LH

更新日期：2011-05-01 00:00:00

abstract：:Signatures of balancing selection can highlight polymorphisms and functions that are important to the long-term fitness of a species. We performed a first genome-wide scan for balancing selection in a bacterial species, Staphylococcus aureus, which is a common cause of serious antimicrobial-resistant infections of hum...

journal_title：Molecular biology and evolution

authors： Thomas JC,Godfrey PA,Feldgarden M,Robinson DA

更新日期：2012-04-01 00:00:00

abstract：:The relative evolutionary rates at individual sites in proteins are informative measures of conservation or adaptation. Often used as evolutionarily aware conservation scores, relative rates reveal key functional or strongly selected residues. Estimating rates in a phylogenetic context requires specifying a protein su...

journal_title：Molecular biology and evolution

authors： Spielman SJ,Kosakovsky Pond SL

更新日期：2018-09-01 00:00:00

abstract：:zeta-Crystallin is a novel nicotinamide adenine dinucleotide phosphate:quinone reductase, present at enzymatic levels in various tissues of different species, which is highly expressed in the lens of some hystricomorph rodents and camelids. We report here the complementary DNA (cDNA) cloning of zeta-crystallin from li...

journal_title：Molecular biology and evolution

authors： Gonzalez P,Hernández-Calzadilla C,Rao PV,Rodriguez IR,Zigler JS Jr,Borrás T

更新日期：1994-03-01 00:00:00

abstract：:With the desire to model population genetic processes under increasingly realistic scenarios, forward genetic simulations have become a critical part of the toolbox of modern evolutionary biology. The SLiM forward genetic simulation framework is one of the most powerful and widely used tools in this area. However, its...

journal_title：Molecular biology and evolution

authors： Haller BC,Messer PW

更新日期：2019-03-01 00:00:00