MAFFT multiple sequence alignment software version 7: improvements in performance and usability.

abstract：:Multiple kelch13 alleles conferring artemisinin resistance (ART-R) are currently spreading through Southeast Asian malaria parasite populations, providing a unique opportunity to observe an ongoing soft selective sweep, investigate why resistance alleles have evolved multiple times and determine fundamental population...

journal_title：Molecular biology and evolution

authors： Anderson TJ,Nair S,McDew-White M,Cheeseman IH,Nkhoma S,Bilgic F,McGready R,Ashley E,Pyae Phyo A,White NJ,Nosten F

更新日期：2017-01-01 00:00:00

abstract：:Vitamin B(12) (cobalamin) is a dietary requirement for humans because it is an essential cofactor for two enzymes, methylmalonyl-CoA mutase and methionine synthase (METH). Land plants and fungi neither synthesize or require cobalamin because they do not contain methylmalonyl-CoA mutase, and have an alternative B(12)-i...

journal_title：Molecular biology and evolution

authors： Helliwell KE,Wheeler GL,Leptos KC,Goldstein RE,Smith AG

更新日期：2011-10-01 00:00:00

abstract：:There are many examples of groups (such as birds, bees, mammals, multicellular animals, and flowering plants) that have undergone a rapid radiation. In such cases, where there is a combination of short internal and long external branches, correctly estimating and rooting phylogenetic trees is known to be a difficult p...

journal_title：Molecular biology and evolution

authors： Shavit L,Penny D,Hendy MD,Holland BR

更新日期：2007-11-01 00:00:00

abstract：:Here we report the peculiarities of molecular evolution and divergence of paralogous heterochromatic clusters of the testis- expressed X-linked Stellate and Y-linked Su(Ste) tandem repeats. It was suggested that Stellate and Su(Ste) clusters affecting male fertility are the amplified derivatives of the unique euchroma...

journal_title：Molecular biology and evolution

authors： Kogan GL,Epstein VN,Aravin AA,Gvozdev VA

更新日期：2000-05-01 00:00:00

abstract：:Human DNA variation is currently a subject of intense research because of its importance for studying human origins, evolution, and demographic history and for association studies of complex diseases. A approximately 10-kb region on chromosome 1, which contains only four small exons (each <155 bp), was sequenced for 6...

journal_title：Molecular biology and evolution

authors： Yu N,Zhao Z,Fu YX,Sambuughin N,Ramsay M,Jenkins T,Leskinen E,Patthy L,Jorde LB,Kuromori T,Li WH

更新日期：2001-02-01 00:00:00

abstract：:Repeated attempts to map the genomic basis of complex traits often yield different outcomes because of the influence of genetic background, gene-by-environment interactions, and/or statistical limitations. However, where repeatability is low at the level of individual genes, overlap often occurs in gene ontology categ...

journal_title：Molecular biology and evolution

authors： Telonis-Scott M,Sgrò CM,Hoffmann AA,Griffin PC

更新日期：2016-04-01 00:00:00

abstract：:In numerous species, individual dispersal is restricted in space so that "continuous" populations evolve under isolation by distance. A method based on individual genotypes assuming a lattice population model was recently developed to estimate the product Dsigma2, where D is the population density and sigma2 is the av...

journal_title：Molecular biology and evolution

authors： Leblois R,Estoup A,Rousset F

更新日期：2003-04-01 00:00:00

abstract：:Transfer RNA (tRNA) is essential for the translation of genetic information into proteins, and understanding its molecular evolution is important if we are to understand the genetic code. In general, long variable-arm (V-arm) structures form in tRNA(Leu), tRNA(Ser), and bacterial and organellar tRNA(Tyr). However, as ...

journal_title：Molecular biology and evolution

authors： Hamashima K,Tomita M,Kanai A

更新日期：2016-02-01 00:00:00

abstract：:Plant phenotypic plasticity describes altered phenotypic performance of an individual when grown in different environments. Exploring genetic architecture underlying plant plasticity variation may help mitigate the detrimental effects of a rapidly changing climate on agriculture, but little research has been done in t...

journal_title：Molecular biology and evolution

authors： Liu N,Du Y,Warburton ML,Xiao Y,Yan J

更新日期：2020-11-03 00:00:00

abstract：:Microbial species play important roles in different environments and the production of high-quality genomes from metagenome data sets represents a major obstacle to understanding their ecological and evolutionary dynamics. Metagenome-Assembled Genomes Orchestra (MAGO) is a computational framework that integrates and s...

journal_title：Molecular biology and evolution

authors： Murovec B,Deutsch L,Stres B

更新日期：2020-02-01 00:00:00

abstract：:The spacer between the 16S and 23S rRNA genes of the chloroplast DNA has been implicated as an origin of replication in several species of plants. In the evening primrose, Oenothera, this site was found to vary greatly in size, with plastid genomes (plastomes) being readily distinguished. To determine whether plastome...

journal_title：Molecular biology and evolution

authors： Sears BB,Stoike LL,Chiu WL

更新日期：1996-07-01 00:00:00

abstract：:Cancer progression is an evolutionary process. During this process, evolving cancer cell populations encounter restrictive ecological niches within the body, such as the primary tumor, circulatory system, and diverse metastatic sites. Efforts to prevent or delay cancer evolution-and progression-require a deep understa...

journal_title：Molecular biology and evolution

authors： Somarelli JA,Gardner H,Cannataro VL,Gunady EF,Boddy AM,Johnson NA,Fisk JN,Gaffney SG,Chuang JH,Li S,Ciccarelli FD,Panchenko AR,Megquier K,Kumar S,Dornburg A,DeGregori J,Townsend JP

更新日期：2020-02-01 00:00:00

abstract：:Wolbachia bacteria infect about half of all arthropods, with diverse and extreme consequences ranging from sex-ratio distortion and mating incompatibilities to protection against viruses. These phenotypic effects, combined with efficient vertical transmission from mothers to offspring, satisfactorily explain the invas...

journal_title：Molecular biology and evolution

authors： Bailly-Bechet M,Martins-Simões P,Szöllosi GJ,Mialdea G,Sagot MF,Charlat S

更新日期：2017-05-01 00:00:00

abstract：:Large-scale variation in chromosome size was analyzed in 35 natural isolates of Escherichia coli by physical mapping with a restriction enzyme whose sites are restricted to rDNA operons. Although the genetic maps and chromosome lengths of the laboratory strains E. coli K12 and Salmonella enterica sv. Typhimurium LT2 a...

journal_title：Molecular biology and evolution

authors： Bergthorsson U,Ochman H

更新日期：1998-01-01 00:00:00

abstract：:There are three common alleles (A, B, and O) at the human ABO blood group locus. We compared nucleotide sequences of these alleles, and relatively large numbers of nucleotide differences were found among them. These differences correspond to the divergence time of at least a few million years, which is unusually large...

journal_title：Molecular biology and evolution

authors： Saitou N,Yamamoto F

更新日期：1997-04-01 00:00:00

abstract：:Crabs of the infra-order Brachyura are one of the most diverse groups of crustaceans with approximately 7,000 described species in 98 families, occurring in marine, freshwater, and terrestrial habitats. The relationships among the brachyuran families are poorly understood due to the high morphological complexity of th...

journal_title：Molecular biology and evolution

authors： Tsang LM,Schubart CD,Ahyong ST,Lai JC,Au EY,Chan TY,Ng PK,Chu KH

更新日期：2014-05-01 00:00:00

abstract：:Genealogical trees have been constructed using mitochondrial ND5 gene sequences of 78 Damaster (s. str.) specimens from all over the Japanese Islands. Eight lineages (called races in this paper) have been recognized. The races are tightly linked to geography with sharp distribution boundaries between them. The races a...

journal_title：Molecular biology and evolution

authors： Su ZH,Tominaga O,Okamoto M,Osawa S

更新日期：1998-08-01 00:00:00

abstract：:Mouse has emerged as the most common model organism in biomedicine. Here, we analyzed the tolerance to the loss-of-function (LoF) of selenoprotein genes, estimated from mouse knockouts and the frequency of LoF variants in humans. We found not only a general correspondence in tolerance (e.g., GPX1, GPX2) and intoleranc...

journal_title：Molecular biology and evolution

authors： Santesmasses D,Mariotti M,Gladyshev VN

更新日期：2020-02-01 00:00:00

abstract：:The 20 protein-coding amino acids are found in proteomes with different relative abundances. The most abundant amino acid, leucine, is nearly an order of magnitude more prevalent than the least abundant amino acid, cysteine. Amino acid metabolic costs differ similarly, constraining their incorporation into proteins. O...

journal_title：Molecular biology and evolution

authors： Krick T,Verstraete N,Alonso LG,Shub DA,Ferreiro DU,Shub M,Sánchez IE

更新日期：2014-11-01 00:00:00

abstract：:The rate of recombination impacts on rates of protein evolution for at least two reasons: it affects the efficacy of selection due to linkage and influences sequence evolution through the process of GC-biased gene conversion (gBGC). We studied how recombination, via gBGC, affects inferences of selection in gene sequen...

journal_title：Molecular biology and evolution

authors： Bolívar P,Mugal CF,Rossi M,Nater A,Wang M,Dutoit L,Ellegren H

更新日期：2018-10-01 00:00:00

abstract：:In a series of highly influential publications, Cavalli-Sforza and colleagues used principal component (PC) analysis to produce maps depicting how human genetic diversity varies across geographic space. Within Europe, the first axis of variation (PC1) was interpreted as evidence for the demic diffusion model of agricu...

journal_title：Molecular biology and evolution

authors： François O,Currat M,Ray N,Han E,Excoffier L,Novembre J

更新日期：2010-06-01 00:00:00

abstract：:The structural genes for nitrogenase, nifK, nifD, and nifH, are crucial for nitrogen fixation. Previous phylogenetic analysis of the amino acid sequence of nifH suggested that this gene had been horizontally transferred from a proteobacterium to the gram-positive/cyanobacterial clade, although the confounding effects ...

journal_title：Molecular biology and evolution

authors： Hirsch AM,McKhann HI,Reddy A,Liao J,Fang Y,Marshall CR

更新日期：1995-01-01 00:00:00

abstract：:Selection on codon usage bias is well documented in a number of microorganisms. Whether codon usage is also generally shaped by natural selection in large organisms, despite their relatively small effective population size (Ne), is unclear. In animals, the population genetics of codon usage bias has only been studied ...

journal_title：Molecular biology and evolution

authors： Galtier N,Roux C,Rousselle M,Romiguier J,Figuet E,Glémin S,Bierne N,Duret L

更新日期：2018-05-01 00:00:00

abstract：:Direct sequencing of polymerase chain reaction products is now an expanding area of plant systematics and evolution. Within angiosperms the rbcL gene has been widely sequenced and used for inferring plant phylogenies at higher taxonomic levels. Unfortunately rbcL does not usually contain enough information to resolve ...

journal_title：Molecular biology and evolution

authors： Gielly L,Taberlet P

更新日期：1994-09-01 00:00:00

abstract：:The ancestral homeland of Australian dingoes and Pacific dogs is proposed to be in South China. However, the location and timing of their dispersal and relationship to dog domestication is unclear. Here, we sequenced 7,000- to 2,000-year-old complete mitochondrial DNA (mtDNA) genomes of 27 ancient canids (one gray wol...

journal_title：Molecular biology and evolution

authors： Zhang M,Sun G,Ren L,Yuan H,Dong G,Zhang L,Liu F,Cao P,Ko AM,Yang MA,Hu S,Wang GD,Fu Q

更新日期：2020-05-01 00:00:00

abstract：:Phenotypic plasticity results in a diversity of phenotypes from a single genotype in response to environmental cues. To understand the molecular basis of phenotypic plasticity, studies have focused on differential gene expression levels between environmentally determined phenotypes. The extent of alternative splicing ...

journal_title：Molecular biology and evolution

authors： Grantham ME,Brisson JA

更新日期：2018-08-01 00:00:00

abstract：:We report the presence of four nuclear paralogs of a 380-bp segment of cytochrome b in callitrichine primates (marmosets and tamarins). The mitochondrial cytochrome b sequence and each nuclear paralog were obtained from several species, allowing multiple comparisons of rates and patterns of substitution both between m...

journal_title：Molecular biology and evolution

authors： Mundy NI,Pissinatti A,Woodruff DS

更新日期：2000-07-01 00:00:00

abstract：:The cosmopolitan dinoflagellate genus Alexandrium, and especially the A. tamarense species complex, contain both toxic and nontoxic strains. An understanding of their evolution and paleogeography is a necessary precursor to unraveling the development and spread of toxic forms. The inclusion of more strains into the ex...

journal_title：Molecular biology and evolution

authors： John U,Fensome RA,Medlin LK

更新日期：2003-07-01 00:00:00

abstract：:The shikimate dehydrogenases (SDH) represent a widely distributed enzyme family with an essential role in secondary metabolism. This superfamily had been previously subdivided into 4 enzyme groups (AroE, YdiB, SdhL, and RifI), which show clear biochemical and functional differences ranging from amino acid biosynthesis...

journal_title：Molecular biology and evolution

authors： Singh S,Stavrinides J,Christendat D,Guttman DS

更新日期：2008-10-01 00:00:00

abstract：:Insertion and deletion (indel)-based analyses have great potential for rooting the tree of life, but their use has been limited because they require ubiquitous sequences that have not been horizontally/laterally transferred. Very few such sequences exist. Here we describe and demonstrate a new algorithm that can use n...

journal_title：Molecular biology and evolution

authors： Lake JA,Herbold CW,Rivera MC,Servin JA,Skophammer RG

更新日期：2007-01-01 00:00:00