Pathophysiology, signs, and symptoms of acute tumor lysis syndrome.

Abstract:

OBJECTIVES:To provide a review of the pathophysiology and corresponding signs and symptoms of tumor lysis syndrome (TLS); to review clinical and laboratory monitoring parameters. DATA SOURCES:Primary and tertiary literature and clinical experience. CONCLUSIONS:An understanding of the pathophysiology of TLS, meticulous assessment for signs and symptoms and monitoring of laboratory data, as well as early recognition of problems are essential for optimal patient outcomes. IMPLICATIONS FOR NURSING PRACTICE:Knowledge of the pathophysiology of TLS will assist the oncology nurse in better understanding the overall syndrome and allow improved patient care management through close clinical and laboratory monitoring of signs and symptoms, and, ideally, promote a proactive approach to managing TLS.

journal_name

Semin Oncol Nurs

authors

Kaplow R

doi

10.1016/s0749-2081(02)80100-0

subject

Has Abstract

pub_date

2002-08-01 00:00:00

pages

6-11

issue

3 Suppl 3

eissn

0749-2081

issn

1878-3449

pii

S0749-2081(02)80100-0

journal_volume

18

pub_type

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