Molecular diagnostic testing in breast cancer.

Abstract:

OBJECTIVES:An overview of molecular tests used in the treatment of breast cancer, organized by stage and clinical condition. DATA SOURCES:Systematic review of scientific literature, guideline recommendations, and data published by test manufacturers. CONCLUSION:Several molecular tests that analyze expression of cancer-related genes have been validated in clinical trials and are recommended by clinical practice guidelines to inform diagnosis and treatment decisions for personalized interventions. IMPLICATIONS FOR NURSING PRACTICE:Molecular testing has become an important part of patient care for those with breast cancer. Oncology nurses must understand this methodology to prescribe tests, interpret the results, and provide guidance to patients.

journal_name

Semin Oncol Nurs

authors

Berse B,Lynch JA

doi

10.1016/j.soncn.2015.02.008

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

108-21

issue

2

eissn

0749-2081

issn

1878-3449

pii

S0749-2081(15)00024-8

journal_volume

31

pub_type

杂志文章,评审
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