Abstract:
:In the prevention of coronary heart disease the aim to achieve the target cholesterol and triglyceride levels and the maximal risk reduction leads to the combination of lipid lowering agents. The importance of the combination is supported by the fact that in monotherapy use of the high dose of the drugs, the lipid lowering effect is modest and the side effects are more frequent. The combined therapy is expected to be used more frequently despite the fact, that the improperly applied combination could have serious unfavourable effects. The authors review the advantages and drawbacks of the fibrate-statin combination, which could be used in the most frequent lipid abnormality, the high cholesterol and high triglyceride level, when the combination of micronized fenofibrate and fluvastatin is recommended. Beside the co-administration of other lipid lowering drugs (nicotine acid and resins), it is discussed the combination of statins and fibrates with a new, cholesterol absorption inhibitor, ezetimibe, a well tolerated drug with advantageous safety profile. Considering further metabolic risks the combination of lipid lowering drugs with glitazones, hormone replacement therapy, homocysteine reducing agents is as well highlighted.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Márk L,Császár Asubject
Has Abstractpub_date
2002-08-25 00:00:00pages
1973-8issue
34eissn
0030-6002issn
1788-6120journal_volume
143pub_type
杂志文章,评审相关文献
ORVOSI HETILAP文献大全abstract::Circulating markers of neuroendocrine tumours are useful tools in the diagnosis of these tumours. Laboratory tests for general biomarkers have acceptable sensitivity for the recognition of neuroendocrine tumours as these biologically active proteins are typically synthesized by all types of neuroendocrine cells. Measu...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2014.30035
更新日期:2014-11-09 00:00:00
abstract::The past two decades are considered as the golden age of the clinical research of mitochondrial DNA. The number of disease-associated pathologic variants is still expanding; the available knowledge about the entities caused by the abnormalities of the mitochondrial DNA is gradually increasing. The inheritance of the m...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2007.28014
更新日期:2007-05-27 00:00:00
abstract::Helicobacter pylori, discovered 27 years ago, has remained the most prevalent infectious agent in the world. In the author's hypothesis, the increase of peptic ulcer prevalence in the 19-20th century could be attributable to the extended worldwide use of gastric tubes for secretory testing which led to the iatrogenic ...
journal_title:Orvosi hetilap
pub_type: 历史文章,杂志文章,评审
doi:10.1556/OH.2010.28982
更新日期:2010-12-05 00:00:00
abstract:UNLABELLED:The swine-origin new influenza variant A(H1N1) emerged in 2009 and changed the epidemiology of the 2009/2010 influenza season globally and at national level. AIMS:The aim of the authors was to analyse the cases of two influenza seasons. METHODS:The Medical and Health Sciences Centre of Debrecen University ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2012.29329
更新日期:2012-04-29 00:00:00
abstract:PATIENT AND METHODS:174 patients who had cardiac adenocarcinoma were examined in the endoscopic laboratory of the Surgical Department between March 1, 1994 and October 29, 2002. In the course of the endoscopic examinations intramural metastases were found in 19 patients (10.9%). Of the patients with esophageal metastas...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2004-01-18 00:00:00
abstract:INTRODUCTION:Studies on well-being of students in higher education are in the centre of international research interest, because adult health as a value plays an important role in the life of future generation. AIM:The authors studied variables that affect the value of well-being (satisfaction with life, student succe...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2016.30572
更新日期:2016-10-01 00:00:00
abstract:INTRODUCTION:The internationalization of societies and the processes of globalization raise new challenges towards health provision systems, including professional, ethical, social, cultural and communicational references of nursing and nursing education. AIMS:In this study the authors wanted to answer the following q...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2012.29479
更新日期:2012-10-28 00:00:00
abstract::Invasive prenatal testing and conventional G-banding chromosome analysis have been considered to be the gold standard of fetal cytogenetic diagnosis. Standard karyotyping is, however, constrained by the limits of the resolution of using a microscope. The advantage of molecular karyotyping, array based methods is the e...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/650.2019.31322
更新日期:2019-03-01 00:00:00
abstract::Anxiety frequently develops in human life and it is usually useful for the organism. Anxiety helps accomodation to the social environment, however, it may be harmful when it is intensive and long-lasting. It can also cause psychosomatic diseases. Anxiety may present itself as mild or moderate stress, psychosomatic dis...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2014.29925
更新日期:2014-06-01 00:00:00
abstract:INTRODUCTION:Gleason grading is the most common method of prostate cancer classification. AIM:The aim of the authors was to assess the reproducibility of Gleason grading among pathologists using the same needle biopsy samples. METHOD:23 pathologists examined 37 prostate cancer biopsies stained with hematoxylin and eo...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2013.29659
更新日期:2013-08-04 00:00:00
abstract::HHV-6A in vitro augments expression of CD4 molecules on the surface of immune cells, facilitates HIV replication and cell death in dual infections. It is hardly known whether these processes take place in vivo; does HHV-6A enhance HIV infection and AIDS progression? To study HHV-6A fresh infections and reactivation, I...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1999-08-22 00:00:00
abstract::The authors detected Epstein-Barr virus (EBV) virus capsid (VCA) antibodies of IgM and IgG type together with EBNA and heterophil antibodies in the sera collected from 1882 unselected patients without infectious mononucleosis. Out of them IgM type antibodies were found in 123 cases and in an additional group of 30 pat...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1996-07-28 00:00:00
abstract::The authors present a case in which a patient, treated with Myleran for chronic myeloid leukaemia showed tumour like changes in the lung. They stress the differential diagnostic difficulties and the importance of histological diagnosis. This case proves that with discontinuation of the therapy the lung change may be r...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1993-03-28 00:00:00
abstract:INTRODUCTION:The TNM classification of breast carcinomas has substantially changed. Both the newly implemented Hungarian breast cancer screening programme and the national cancer registry require the adequate reporting of the disease with particular emphasis on its extent. AIMS:The purpose of this article is to introd...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2003-08-10 00:00:00
abstract::The simultaneous recording of urodynamic parameters and x-ray imaging of the lower urinary tract is the ideal technique for a complex investigation of the lower urinary tract morphology and function. The urodynamic and micturating cystourethrography findings were reviewed in 57 children. The causes of the examinations...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1992-12-20 00:00:00
abstract::The effect of a once a day dose one or one and a half mg bopindolol on mild to moderate hypertensive patients was studied. During the treatment the changes in blood pressure, heart rate, serum triglyceride, cholesterin, HDL cholesterin were examined. The drug was given as monotherapy to 9 previously untreated patients...
journal_title:Orvosi hetilap
pub_type: 临床试验,杂志文章
doi:
更新日期:1991-09-29 00:00:00
abstract:INTRODUCTION:The prevalence of invasive pneumococcal disease, which is depending on risk factors and comorbidities, is increasing over the age of 50 years. Most developed countries have recommendations but vaccination rates remain low. AIM:To assess the general practitioners' daily practice in relation to pneumococcal...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2015.30054
更新日期:2015-02-01 00:00:00
abstract::The rate of homebirth decreased significantly by the 20th century, however, the practice has never disappeared. The Hungarian government issued a regulation of out-of-hospital birth in 2011, then allowed midwives to provide prenatal care for low-risk mothers in 2014. These were great steps toward the midwifery model o...
journal_title:Orvosi hetilap
pub_type: 历史文章,杂志文章,评审
doi:10.1556/650.2016.30364
更新日期:2016-03-13 00:00:00
abstract:INTRODUCTION:Retrospective analysis on some factors possibly influencing survival rate of very low birthweight infants on respiratory life support has been carried out. AIM:The aim was to find out about roles played by prenatal steroid prophylaxis, neonatal surfactant therapy and methods of reduction of complication r...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2004-06-06 00:00:00
abstract::Proton pump inhibitors (PPIs) are widely used for the treatment of gastroesophageal reflux disease, as well as other acid-related disorders. Omeprazole, lansoprazole, pantoprazole, rabeprazole and esomeprazole effectively suppress gastric acid secretion by blocking the gastric acid pump, H+/K+ -adenosine triphosphatas...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2007.27902
更新日期:2007-03-25 00:00:00
abstract::The prevalence of allergic diseases has been increasing recently. Allergy has various symptoms. Allergic eye diseases (seasonal and perennial allergic conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, giant papillary conjunctivitis, contact blepharoconjunctivitis) are common in atopic patients....
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2019.31265
更新日期:2019-03-01 00:00:00
abstract::In the Department of Pathology of Albert Szent-Györgyi Medical University at Szeged in Hungary 37,504 autopsies were performed in the last 30 years and double multiple primary malignant tumours were found in 385 cases (4.2%). In thyroid cancer cases the tumours of other organs were more frequent (22.7%), and these tum...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1991-03-17 00:00:00
abstract::The leukocyte migration inhibition test is a method used to assess the cell-mediated immune function. The authors examined 251 samples for a period of 3 years; 169 samples from celiac patients and 82 were control. The sensitivity of this test was 34/35 (97%) in proved gluten sensitive patients, but this was found afte...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1990-11-11 00:00:00
abstract::This article reviews the recent changes in the understanding of acute pancreatitis pathophysiology emphasizing results deriving from the more detailed comprehension of the local and systemic aspects of the inflammatory process. The authors briefly discuss those theories that have been influencing the basic philosophie...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2000-02-06 00:00:00
abstract::Introduction: Chronic obstructive pulmonary disease (COPD) is a multifactorial disorder, therefore, airflow limitation alone does not reflect the full burden of COPD. In Hungary, no national data are available yet about the results obtained with the different COPD questionnaires in daily patient care, and about diffic...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31661
更新日期:2020-02-01 00:00:00
abstract:UNLABELLED:In a retrospective evaluation, the outcome of the long term treatment of the sphincter of Oddi dyskinesia (OD, type III. dysfunction) has been analysed. PATIENTS AND METHOD:Therapeutic results of 64 cholecystectomised patients with OD were evaluated by means of regular follow-up and questionnaire filled in ...
journal_title:Orvosi hetilap
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-10-01 00:00:00
abstract:UNLABELLED:Previous studies have found that many high-risk patients are not achieving their LDL-cholesterol goals, and many patients, despite being treated with lipid-lowering therapy, also have elevated triglycerides and/or low levels of HDL-cholesterol. AIMS:Authors analyzed the treatment strategies for dyslipidemic...
journal_title:Orvosi hetilap
pub_type: 临床试验,杂志文章
doi:10.1556/OH.2011.29127
更新日期:2011-05-22 00:00:00
abstract::Following the failure of conventional diagnostic procedures, whole-body FDG-PET investigations were carried out in 42 metastatic cancer patients to localize occult primary carcinomas. During the clinical follow-up, the presence of malignant tumor was ruled out in 3 cases, and 2 patients originally believed to have car...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2002-05-26 00:00:00
abstract::We have used minimal invasive therapy in the treatment of pancreatic diseases for a long time. CT and/or ultrasound guided techniques have been used for the treatment of pancreatic pseudocysts for more than 20 years. The development of technology has also made an opportunity for the extensive use of laparoscopic surge...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2008.28484
更新日期:2008-11-30 00:00:00
abstract::Patients seeking help from gastroenterologist have frequent complaints of changes in the quality and quantity of stool as well in the frequency of bowel movements. Definition of diarrhea includes: more than three bowel movements daily, more than 200 grams of the stool daily, and its water content exceeding 75-85%. Dia...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2009.28709
更新日期:2009-08-30 00:00:00