[Application of corticosteroid eye drops for allergic eye diseases in children].

Abstract:

:The prevalence of allergic diseases has been increasing recently. Allergy has various symptoms. Allergic eye diseases (seasonal and perennial allergic conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, giant papillary conjunctivitis, contact blepharoconjunctivitis) are common in atopic patients. Treatment options for allergic conjunctivitis include local and systemic antihistamines, mast cell stabilizers, dual-action agents, vasoconstrictors and corticosteroids. Treatment seems easy, but inappropriate therapy - in extreme cases - can lead to vision loss. Corticosteroid eyedrops provide effective relief of symptoms, however, their use is limited due to their severe side effects. Both steroid-induced cataract and steroid-induced glaucoma are dangerous for vision. The characteristics, frequency and risks of these side effects have been studied widely in adults, but there are very few studies focused on children. According to the present studies, the side effects of topically administered corticosteroids appear more often in children than in adults. Orv Hetil. 2019; 160(9): 329-337. :Absztrakt: Napjainkban az allergiás megbetegedések száma folyamatosan emelkedik. Az atópiás betegeknél gyakran jelentkeznek szemet érintő allergiás megbetegedések (szezonális és perennialis allergiás kötőhártya-gyulladás, vernalis keratoconjunctivitis, atópiás keratoconjunctivitis, óriás papillás kötőhártya-gyulladás, kontaktblepharoconjunctivitis). Az allergiás szembetegségek kezelésében szemcsepp formájában használt gyógyszerek közé tartoznak az antihisztaminok, a hízósejtmembrán-stabilizálók, a kettős támadáspontú szerek, az érösszehúzók és a kortikoszteroidok. Egyes esetekben szisztémásan antihisztaminok is használhatók. A kezelés látszólag egyszerű, a helytelen terápia azonban – szélsőséges esetben – akár látásvesztéshez is vezethet. A szemtünetek enyhítésében a kortikoszteroidok kiváló gyógyszernek számítanak, de használatuk jelentős figyelmet igényel mind a kezelőorvos, mind a beteg részéről, hiszen súlyos mellékhatásaik vannak. Ezek közül a látást leginkább veszélyeztető elváltozások a szteroidindukált szürke hályog és a még súlyosabb szteroidindukált glaukóma. Felnőttek körében e két kórkép jellemzőit, előfordulási gyakoriságát és kockázati tényezőit részletesen tanulmányozták, ellenben gyermekek esetében igen kevés irodalmi adat áll rendelkezésünkre a szteroidszemcsepp mellékhatásaival kapcsolatosan. Az eddigi tanulmányok alapján gyermekeknél sokkal nagyobb arányban alakulnak ki mellékhatások a szteroidterápia mellett, mint felnőttek körében. Orv Hetil. 2019; 160(9): 329–337.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Csorba A,Soproni A,Maneschg O,Nagy ZZ,Szamosi A

doi

10.1556/650.2019.31265

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

329-337

issue

9

eissn

0030-6002

issn

1788-6120

journal_volume

160

pub_type

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