Accuracy of a commercial enzyme-linked immunosorbent assay for CagA in patients from Brazil with and without gastric carcinoma.

Abstract:

:We validated a commercial enzyme-linked immunosorbent assay for the detection of anti-CagA antibodies in Brazilian patients with Helicobacter pylori infection. The test presented high sensitivity (97.4%) and specificity (88.9%) when employed in patients without gastric carcinoma. However, in gastric carcinoma patients, the test was neither sensitive nor specific enough to detect cagA-positive H. pylori infection.

journal_name

J Clin Microbiol

authors

Rocha AM,Rocha GA,Santos A,de Oliveira CA,Queiroz DM

doi

10.1128/jcm.41.1.447-448.2003

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

447-8

issue

1

eissn

0095-1137

issn

1098-660X

journal_volume

41

pub_type

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