Abstract:
:The clinical, hematological, and cytogenetic data from two young adults with acute myeloid leukemia (AML) FAB type M1 is described. At diagnosis, cytogenetic investigation revealed the presence of the translocation t(6;9)(p23;q34). Bone marrow basophilia was not detected in either patient nor was there any evidence of preceding or underlying myelodysplasia. Both patients achieved complete remission (CR) and one patient remains in CR of over 5 years duration. It is suggested that the presence of basophilia may be associated with the myelodysplasia rather than the chromosome anomaly t(6;9).
journal_name
Leukemiajournal_title
Leukemiaauthors
Lillington DM,MacCallum PK,Lister TA,Gibbons Bsubject
Has Abstractpub_date
1993-04-01 00:00:00pages
527-31issue
4eissn
0887-6924issn
1476-5551journal_volume
7pub_type
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