Soluble Fas (CD95/Apo-1), soluble Fas ligand, and activated caspase 3 in the cerebrospinal fluid of infants with posthemorrhagic and nonhemorrhagic hydrocephalus.

abstract：:Antigenic analysis of neuroblastoma cells was performed by autologous typing and indirect immunofluorescent test combined with absorption tests. Serum of a patient with neuroblastoma before treatment showed weak reactivity with cultured autologous neuroblastoma cells, while serum obtained from the same patient 3 month...

journal_title：Pediatric research

authors： Kawai K,Sakatoku H,Matsuda T,Kazuoka K,Kubo S,Kamiya H,Sakurai M

更新日期：1986-10-01 00:00:00

abstract：:Simultaneous measurements of serum immunoreactive thyrocalcitonin (iTCT), immunoreactive parathyroid hormone (iPTH), calcium, inorganic phosphate, magnesium, and alkaline phosphatase were made in 37 normal children whose ages ranged from 6-12 years. Between the ages of 6 and 12 there is a statistically significant ris...

journal_title：Pediatric research

authors： Shainkin-Kerstenbaum R,Funkenstein B,Conforti A,Shani S,Berlyne GM

更新日期：1977-02-01 00:00:00

abstract：:To determine whether human milk contained soluble receptors and cytokine antagonists that might contribute to its anti-inflammatory properties, ELISA and enzyme-amplified sensitivity immunoassay methods were used to quantitate soluble intercellular and vascular cell adhesion molecules, soluble E-selectin, soluble IL-6...

journal_title：Pediatric research

authors： Buescher ES,Malinowska I

更新日期：1996-12-01 00:00:00

abstract：:A girl presented with an important growth retardation, hepatomegaly, fasting hypoglycemia, lactic acidosis, increased serum cholesterol, triglycerides and uric acid, and increased liver glycogen (7.5%). There was no rise in blood glucose after IV galactose or fructose, but glucagon gave a delayed response. Type Ib gly...

journal_title：Pediatric research

authors： Corbeel L,Hue L,Lederer B,De Barsy T,Van den Berghe G,Devlieger H,Jaeken J,Bracke P,Eeckels R

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:The prevalence of vitamin D (vitD) deficiency presenting as rickets is increasing worldwide. Insufficient sun exposure, vitD administration, and/or calcium intake are the main causes. However, vitD system-related genes may also have a role. METHODS:Prospective study: 109 rachitic children completed a 6-mo s...

journal_title：Pediatric research

authors： El Kholy M,Elsedfy H,Fernández-Cancio M,Hamza RT,Amr NH,Ahmed AY,Toaima NN,Audí L

更新日期：2017-02-01 00:00:00

abstract：:Chronic disease risk is inextricably linked to our early-life environment, where maternal, fetal, and childhood factors predict disease risk later in life. Currently, maternal obesity is a key predictor of childhood obesity and metabolic complications in adulthood. Although the mechanisms are unclear, new and emerging...

journal_title：Pediatric research

authors： Gohir W,Ratcliffe EM,Sloboda DM

更新日期：2015-01-01 00:00:00

abstract：:Hereditary surfactant protein B (SP-B) deficiency has been lethal in the first year of life without lung transplantation. We tested the hypothesis that SP-B gene mutations may result in milder phenotypes by investigating the mechanisms for lung disease in two children with less severe symptoms than have been previousl...

journal_title：Pediatric research

authors： Dunbar AE 3rd,Wert SE,Ikegami M,Whitsett JA,Hamvas A,White FV,Piedboeuf B,Jobin C,Guttentag S,Nogee LM

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Real-time detection and classification of apneic episodes remain significant challenges. This study explores the applicability of a novel method of monitoring the respiratory effort and dynamics for rapid detection and classification of apneic episodes. METHODS:Obstructive apnea (OA) and hypopnea/central ap...

journal_title：Pediatric research

authors： Waisman D,Lev-Tov L,Levy C,Faingersh A,Colman Klotzman I,Bibi H,Rotschild A,Landesberg A

更新日期：2015-07-01 00:00:00

abstract：:Evidence is inconsistent or poorly understood for links between polychlorinated biphenyls (PCBs), 1,1'-dichloro-2,2'-bis(4-chlorophenyl)ethylene (DDE), and organophosphate (OP) pesticides and adverse pregnancy outcomes, although they are known developmental toxicants. We measured biomarkers of maternal exposure to DDE...

journal_title：Pediatric research

authors： Wolff MS,Engel S,Berkowitz G,Teitelbaum S,Siskind J,Barr DB,Wetmur J

更新日期：2007-02-01 00:00:00

abstract：:New information is emerging concerning the influence of environmental factors (e.g., viruses, pollutants, nutrients) on fetal lung development and the prenatal modulation of cellular and molecular effectors essential to the control of airway function, which may shed new light into the pathogenesis of chronic obstructi...

journal_title：Pediatric research

authors： Piedimonte G,Harford TJ

更新日期：2020-01-01 00:00:00

abstract：:Gluconeogenesis decreases during septic shock, but its mechanism is not well known. Tumor necrosis factor alpha (TNF-alpha), which is a key cytokine in septic shock, can increase GLUT1 gene expression and glucose uptake in muscles and fatty tissues. TNF-alpha does not alter the metabolism of hepatocytes in which GLUT2...

journal_title：Pediatric research

authors： Goto M,Yoshioka T,Battelino T,Ravindranath T,Zeller WP

更新日期：2001-04-01 00:00:00

abstract：:Lung deposition of inhaled drugs in ventilated neonates has been studied in models of questionable relevance. With conventional nebulizers, pulmonary deposition has been limited to 1% of the total dose. The objective of this study was to assess lung delivery of aerosols in a model of neonatal ventilation using a conve...

journal_title：Pediatric research

authors： Dubus JC,Vecellio L,De Monte M,Fink JB,Grimbert D,Montharu J,Valat C,Behan N,Diot P

更新日期：2005-07-01 00:00:00

abstract：:Several epithelial ion transporters are developmentally regulated in the preweaning period, at the time when the circulating levels of glucocorticoid and mineralocorticoid hormones increase. The specific role of glucocorticoids and mineralocorticoids in the maturation of epithelial ion transport is still disputed. In ...

journal_title：Pediatric research

authors： Wang ZM,Yasui M,Celsi G

更新日期：1995-08-01 00:00:00

abstract：:Gitelman disease was diagnosed in two unrelated children with hypokalemic metabolic alkalosis and growth failure (a boy and a girl aged 7 mo and 9.5 y, respectively, at clinical presentation) on the basis of mutations detected in the gene encoding the thiazide-sensitive NaCl cotransporter of the distal convoluted tubu...

journal_title：Pediatric research

authors： Bettinelli A,Rusconi R,Ciarmatori S,Righini V,Zammarchi E,Donati MA,Isimbaldi C,Bevilacqua M,Cesareo L,Tedeschi S,Garavaglia R,Casari G

更新日期：1999-08-01 00:00:00

abstract：:Based on the serum phenylalanine levels under free diet patients with hyperphenylalaninemia are classified as "classical" (>1200 micromol/L), "mild" (600-1200 micromol/L), or "non-phenylketonuria (PKU)-hyperphenylalaninemia" (<600 micromol/L). Recent studies revealed intellectual, neurologic, and neuropsychologic defi...

journal_title：Pediatric research

authors： Weglage J,Ullrich K,Pietsch M,Fünders B,Güttler F,Harms E

更新日期：1997-09-01 00:00:00

abstract：:Normative body composition during the first 2 y of life was derived from a prospective study of 76 children. We present 1) fat free mass (FFM) and its components, and fat mass (FM), 2) incremental growth rates partitioned into chemical components, and 3) age-specific and gender-specific constants for converting chemic...

journal_title：Pediatric research

authors： Butte NF,Hopkinson JM,Wong WW,Smith EO,Ellis KJ

更新日期：2000-05-01 00:00:00

abstract：:DNA segments that are separated from the promoter region of a gene by many thousands of bases may nonetheless regulate the transcriptional activity of that gene. This finding has led to the investigation of mechanisms underlying long-range chromatin interactions. In intermitotic cells, chromosomes decondense, filling ...

journal_title：Pediatric research

authors： Ling JQ,Hoffman AR

更新日期：2007-05-01 00:00:00

abstract：:Permeability of the blood brain barrier (BBB) for bilirubin and 125I-albumin was studied in 2-d- and 2-wk-old piglets. 125I-albumin was given by bolus at the beginning of each study. Hyperbilirubinemia was produced by an initial bolus infusion of bilirubin and sustained at a plasma bilirubin:albumin molar ratio of app...

journal_title：Pediatric research

authors： Lee C,Oh W,Stonestreet BS,Cashore WJ

更新日期：1989-05-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) remains among the most common and devastating diseases in neonates. Despite advances in neonatal clinical care, specific treatment strategies and diagnostic modalities remain lacking. As a result, morbidity and mortality remain high. Improved understanding of the pathogenesis of NEC has...

journal_title：Pediatric research

authors： Shelby RD,Raab R,Besner GE,McElroy SJ

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Cerebral white-matter (WM) abnormalities on magnetic resonance imaging (MRI) correlate with neurodevelopmental disability in infants born prematurely. RESULTS:Quantitative histological measures of WM and ventricular volumes correlated with qualitative MRI scores of WM volume loss and ventriculomegaly. Dif...

journal_title：Pediatric research

authors： Griffith JL,Shimony JS,Cousins SA,Rees SE,McCurnin DC,Inder TE,Neil JJ

更新日期：2012-02-01 00:00:00

abstract：:Time-corrected measurements of transplacental and transamniotic electrical potentials were made in potassium-deficient rats on the 20th day of gestation. These averaged 6.4 mV and 2.0 mV, respectively, in the deficient group as compared with 14.3 and 18.4, respectively, in the controls. The measured maternal potassium...

journal_title：Pediatric research

authors： Fantel AG

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is the most common systemic vasculitis syndrome primarily affecting medium-sized arteries, particularly the coronary arteries. Though KD may be associated with immunological problems, the involvement of microRNAs (miRs) has not been fully described. METHODS:We enrolled 23 KD patients a...

journal_title：Pediatric research

authors： Saito K,Nakaoka H,Takasaki I,Hirono K,Yamamoto S,Kinoshita K,Miyao N,Ibuki K,Ozawa S,Watanabe K,Bowles NE,Ichida F

更新日期：2016-09-01 00:00:00

abstract：:Lung development requires extracellular matrix remodeling. This involves matrix metalloproteinases (MMPs) and their endogenous inhibitors [tissue inhibitors of metalloproteinases (TIMPs)]. Because these have been generally studied only in whole lung, we focused specifically on mesenchymal and epithelial cells freshly ...

journal_title：Pediatric research

authors： Boucherat O,Bourbon JR,Barlier-Mur AM,Chailley-Heu B,D'Ortho MP,Delacourt C

更新日期：2007-07-01 00:00:00

abstract：:Prenatal maternal therapy with glucocorticoid reduces the incidence of respiratory distress syndrome (RDS) in premature infants. To investigate the effects of this treatment on the fetal endocrine system, we determined serum concentrations of betamethasone, cortisol, dehydroepiandrosterone sulfate, growth hormone, and...

journal_title：Pediatric research

authors： Ballard PL,Gluckman PD,Liggins GC,Kaplan SL,Grumbach MM

更新日期：1980-02-01 00:00:00

abstract：:The purpose of this investigation was twofold: (1) to identify and characterize the enzymatic ATP hydrolysis system of epithelial cilia, and (2) to develop a quantitative, biochemical test for the ciliotoxic cystic fibrosis (CF) factor based on inhibition of ATP utilization by ciliary preparations. Our rationale for s...

journal_title：Pediatric research

authors： Farrell PM,Fox GN,Spicer SS

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Clinicians could modify dietary interventions during early infancy by monitoring fat and fat-free mass accretion in very preterm infants. METHODS:Preterm infants were randomly assigned to either having reports on infant body composition available to the clinicians caring for them (intervention group) or not...

journal_title：Pediatric research

authors： Salas AA,Jerome ML,Chandler-Laney P,Ambalavanan N,Carlo WA

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:In preterm neonates, peroxides contaminating total parenteral nutrition (TPN) contribute to oxidative stress, which is suspected to be a strong inducer of hepatic complications related to prematurity. Recently, others reported that hexapeptides derived from human milk (HM) exerted free radical-scavenging a...

journal_title：Pediatric research

authors： Miloudi K,Tsopmo A,Friel JK,Rouleau T,Comte B,Lavoie JC

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Caffeine is widely used to manage apnea of prematurity, and reduces the incidence of bronchopulmonary dysplasia (BPD). Deregulated transforming growth factor (TGF)-β signaling underlies arrested postnatal lung maturation in BPD. It is unclear whether caffeine impacts TGF-β signaling or postnatal lung develop...

journal_title：Pediatric research

authors： Rath P,Nardiello C,Surate Solaligue DE,Agius R,Mižíková I,Hühn S,Mayer K,Vadász I,Herold S,Runkel F,Seeger W,Morty RE

更新日期：2017-05-01 00:00:00

abstract：:In order to study the neonatal microcirculation, the capillary hemodynamics in skin was investigated in 43 full-term infants 2-7 days after birth. The nailfold capillaries of the thumb were visualized by means of television microscopy and the capillary blood cell velocity (CBV) was videophotometrically quantified in 1...

journal_title：Pediatric research

authors： Norman M,Herin P,Fagrell B,Zetterström R

更新日期：1988-06-01 00:00:00

abstract：:The investigation was designed to explore the use of tests tapping reversible aspects of behavior and performance and to find out whether these data can be correlated with concurrent metabolic changes in different dietary phases. The four subjects had classic phenylketonuria, diagnosed on the basis of a high level of ...

journal_title：Pediatric research

authors： Anderson VE,Siegel FS

更新日期：1976-01-01 00:00:00