When applied to facial skin, does estrogen ointment have systemic effects?

Abstract:

:We examined cytological vaginal smears of 17 women before and after three months of dermal estrogen (1 g of 0.01% estradiol ointment or 0.3% estriol ointment once daily), applied to the face for dermatological indications. The mean age was 57.1 +/- 7.6 years (range from 46 to 66). Seven women had estrogenic smears (more than 10% superficial cells) before therapy. Nine women were treated with 0.01% estradiol ointment and 8 were treated with 0.3% estriol ointment. Both groups had gynecological examinations including cervical and vaginal smears before and after treatment and also monthly measurements of serum follicle-stimulating hormone, prolactin and estradiol levels. Serum hormone levels and the appearance of vaginal smears showed no significant change during treatment.

journal_name

Arch Gynecol Obstet

authors

Kainz C,Gitsch G,Stani J,Breitenecker G,Binder M,Schmidt JB

doi

10.1007/BF02768732

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

71-4

issue

2

eissn

0932-0067

issn

1432-0711

journal_volume

253

pub_type

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