Abstract:
PURPOSE:To compare the sensitivity, specificity, positive and negative predictive values and accuracy of visual inspection with acetic acid under magnification (VIAM) and colposcopy for detecting cervical intraepithelial neoplasia (CIN) to determine if VIAM can substitute colposcopy in identifying the biopsy site in screen-positive cases. METHODS:A prospective cross-sectional study was carried out on 408 symptomatic multiparous women in the reproductive age group (15-49 years) at a tertiary care teaching hospital. VIAM and colposcopy were used to screen for cervical precancerous lesions. Screen-positive women underwent guided biopsy and endocervical curettage. The site of biopsy was recorded as VIAM guided or colposcopy guided. Histopathology was taken as the gold standard. RESULTS:The mean age was 32.3 ± 6.8 years (range 15-49), whilst the mean parity was 2.9 ± 1.2 (range 1-9). A total of 113 women screened positive. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of VIAM and colposcopy were 95, 78, 19, 99 and 79%, and 86, 79, 18, 99 and 79%, respectively for high-grade lesions. CONCLUSIONS:VIAM can be a useful alternative to colposcopy when the latter is not available, as it has better sensitivity and equivalent specificity for detecting high-grade CIN.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Aggarwal P,Batra S,Gandhi G,Zutshi Vdoi
10.1007/s00404-010-1673-0subject
Has Abstractpub_date
2011-08-01 00:00:00pages
397-403issue
2eissn
0932-0067issn
1432-0711journal_volume
284pub_type
杂志文章abstract:PURPOSE:Superficial peritoneal endometriotic (pEM) lesions are composed of endometrial glands and stroma, in addition to a third component-myofibroblasts and smooth muscles (SM)-like cells. The latter develops secondary to a metaplasia. In this study, we characterised the third component cells in pEM according to diffe...
journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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更新日期:2006-02-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-017-4600-9
更新日期:2018-02-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
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更新日期:2010-11-01 00:00:00