Abstract：
BACKGROUND:Little is known about current practice in using the anticonvulsant gabapentin in the management of cancer-related neuropathic pain. OBJECTIVES:The main objective of this study was to describe the pattern of gabapentin use as an adjuvant analgesic for cancer-related neuropathic pain in patients admitted to a tertiary palliative care unit. METHODS:A retrospective medical chart review for 150 patients admitted to a tertiary palliative care unit over a period of 10 months. Abstracted data included patient characteristics, primary diagnoses, pain scores, and the type and dose of opioids and other adjuvants used. RESULTS:Of the 147 patients with a cancer diagnosis, 45 (31%) had neuropathic pain. Of those, 22 (49%) received gabapentin. The final daily dose of gabapentin ranged from 100 mg-3,000 mg (mean: 941 mg +/- 665 mg; median: 900 mg). Gabapentin was discontinued in 10 patients (46%). Suggested adverse effects included sedation (n = 4), dizziness (n = 1), and bitter taste (n = 1). The change in pain scores was not significantly different in those who continued on gabapentin compared to those who discontinued it. CONCLUSIONS:The retrospective nature of the study and the small sample size render solid conclusions difficult to make. However, gabapentin was discontinued in approximately half the patients who received it, and often when only modest doses were used. Similar studies from other centres may improve understanding of current practices and aid in designing future clinical trials on the subject.
journal_name
J Palliat Carejournal_title
Journal of palliative careauthors
Oneschuk D,al-Shahri MZsubject
Has Abstractpub_date
2003-10-01 00:00:00pages
185-7issue
3eissn
0825-8597issn
2369-5293journal_volume
19pub_type
杂志文章abstract：BACKGROUND::Following the Supreme Court of Canada's Carter Decision, medical assistance in dying (MAID) became possible with individual court orders in February 2016. Subsequently, on June 17, 2016, legislation was passed that eliminated the need for court orders, essentially making physicians the arbiters of these req...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：10.1177/0825859718812446
更新日期：2019-04-01 00:00:00
abstract：:Caregivers are often overwhelmed by the strain of terminal caregiving. We wished to better understand the needs of terminal caregivers and to supply a basis for tailoring interventions to them during caregiving and early bereavement. This report provides a profile of 124 bereaved caregivers interviewed within three mo...
journal_title：Journal of palliative care
pub_type： 杂志文章,多中心研究
doi：
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVE:Palliative, end-of-life care (PEOLC) providers are poorly resourced in addressing the needs of patients with mental health challenges, and the dying experiences of this cohort-particularly those with a comorbid, chronic and persistent mental illness (CPMI)-are poorly documented. We sought to explore the exper...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：10.1177/0825859720951360
更新日期：2020-08-18 00:00:00
abstract：:There may be quantitatively more cancer in the developing world, Africa included, than in the developed world. Unlike in the developed world, cancer patients in Africa present for treatment at a late stage and therefore most of them have pain. Yet, the most commonly used modality for treatment of the cancer pain is dr...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Informal hospice caregivers play a key role in managing patients' pain at home, but lack of adherence to doctor-prescribed analgesic regimens and medication errors are significant barriers to truly effective pain management. A digital pain diary may improve caregiver management of pain at home; however, most digital p...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：10.1177/0825859717722466
更新日期：2017-04-01 00:00:00
abstract：:The anniversary of a death is perceived as a difficult time by the majority of closely bereaved relatives and friends. Bereavement anniversary cards are supportive and useful in the context of wider follow-up. This study identified no strong predictors to indicate those for whom such a card would be inappropriate. Sev...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:Despite very little confirming evidence, one of the most pervasive beliefs about dying is that terminally ill people receive a great deal of health care in the last few days, weeks, or months of life. A secondary analysis of 1992/93 through 1996/97 Alberta inpatient hospital abstracts data was undertaken to explore an...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：2002-04-01 00:00:00
abstract：PURPOSE:The present study assesses the relationship between patient dignity in advanced cancer and the following variables: psychological distress, preparatory grief, and sociodemographic and clinical characteristics. METHODS:The sample consisted of 120 patients with advanced cancer. The self-administered questionnair...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：10.1177/0825859718759882
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The use of chemotherapy at the end of life in advanced cancer patients has increased and end of life care has become increasingly aggressive. The aim of this study is to evaluate patients receiving chemotherapy in the last 3 months of life and the aggressiveness of end-of-life support of these...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：10.1177/0825859720946505
更新日期：2020-08-06 00:00:00
abstract：:This multi-centre study of adjuvant "burst" ketamine in palliative care in-patients documents its effectiveness, duration of pain relief, and adverse effects (AE) profile. Patients received a three-to-five day continuous subcutaneous infusion (CSCI) of ketamine escalated from 100 to 300 to 500 mg/24 hours if required....
journal_title：Journal of palliative care
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：2010-10-01 00:00:00
abstract：:In this paper I have described some of the recent developments in the growth of a patient/survivor movement in Canada. Arguments for the value of increased patient participation include providing a needed balance to the traditional medical perspective, addressing patient needs free from other vested interests, providi...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:When dying patients are young adults or have a contagious disease, nursing staff may feel acutely uncomfortable and the patients may become isolated and alone. Nurses who work in palliative care units (PCU) develop special interactive skills that are generally acknowledged but not clearly defined or understood. Admiss...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：OBJECTIVES:Little is known about how clinicians perceive prognostic uncertainty. Our study objective was to identify factors that influence how prognostic uncertainty is viewed by physicians, as it relates to their communications with families. DESIGN:Thirty semi-structured interviews with qualitative content analysis...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：10.1177/0825859719845005
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:This study aimed to characterize the strategies and psychosocial conditions that influence how resilient people live in the face of advanced cancer. METHODS:Grounded theory interviews and a survey of 10 resilient people with advanced cancer were collected and analyzed. FINDINGS:Personal assets - including p...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：2013-07-01 00:00:00
abstract：:Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality and disability worldwide. For many patients, maximal therapy for COPD produces only modest relief of disabling symptoms and these symptoms result in a significantly reduced quality of life. Despite the high morbidity and mortality, patients w...
journal_title：Journal of palliative care
pub_type： 杂志文章,评审
doi：
更新日期：2005-10-01 00:00:00
abstract：BACKGROUND:Patients with advanced chronic obstructive pulmonary disease (COPD) have a significant symptom burden despite maximal medical therapy, yet few are referred for concomitant palliative care. OBJECTIVE:To evaluate the utilization and impact of palliative care on the location of death and to identify clinical v...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：10.1177/0825859719851486
更新日期：2019-07-02 00:00:00
abstract：AIM:The aim of this study was to characterize the attitudes of older adults on an inpatient palliative care unit toward complementary and alternative medicine (CAM) therapies. METHODS:A consecutive sample of 33 inpatients (61 to 98 years old) completed a questionnaire that examined their attitudes toward CAM to determ...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:The study assessed the components of high-quality HIV palliative care using the multidimensional model of quality assessment developed by Maxwell (4). Data collection consisted of interviews with individual subjects and focus groups. The interviews took place in three London health authorities. Seven service users and...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:This paper presents an overview of a qualitative study of six recently discharged hospice patients, who had experienced at least two episodes of inpatient palliative care and who were interviewed about their experience of care. The resulting data formed a representation--the Circle of Care--with a central theme being ...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：:This paper addresses the music therapy process specific to one subgroup of the general population identified as having terminal illness. This subgroup includes individuals who are impoverished, homeless, and do not have someone to provide them with care at the end of life. Based upon her clinical work at Malachi House...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：2001-10-01 00:00:00
abstract：:The Regional Palliative Care Unit in Ottawa conducted a retrospective study to determine how satisfied patients and families were with the service the Unit offers. Forty-five primary care providers, bereaved from 6 to 12 months, completed the 64-item semistructured telephone interview in a mean time of 20 minutes. The...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：UNLABELLED:In Poland, medical curricula cover palliative care for adults, not for children. This paper evaluates feedback of students who participated in a pilot pediatric palliative care education program. METHOD:An anonymous questionnaire was designed for the students; they were asked to assess each aspect of the pr...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:Inpatient palliative care consultation has been demonstrated to improve quality of life as well as decrease hospital readmissions, intensive care unit transfers, and hospital costs for people with a life limiting illness. The clinical teaching units (CTUs) at London Health Sciences Centre (LHSC) routinely admit patien...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：10.1177/0825859718781363
更新日期：2018-10-01 00:00:00
abstract：:A survey was conducted to determine what pharmaceutical services are provided to palliative care sites in Australia and Canada, and the pharmacist's role on the interdisciplinary team. Questionnaires were sent to 100 selected sites in each country. Questions pertained to demographics and the level of duties performed....
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:A strong and often polarized debate has taken place during recent years concerning the consequences of dehydration in the terminally ill patient. When a patient has a severely restricted oral intake or is found to be dehydrated, the decision to administer fluids should be individualized and made on the basis of a care...
journal_title：Journal of palliative care
pub_type： 杂志文章,评审
doi：
更新日期：1998-07-01 00:00:00
abstract：OBJECTIVE:Practice guidelines indicate that patients who have months to weeks left to live should not be offered chemotherapy. We examined factors associated with clinician-reported poor performance status as determined by the Palliative Performance Scale (PPS) and subsequent initiation of intravenous (IV) chemotherapy...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：2014-10-01 00:00:00
abstract：:This article describes two young, potentially curable patients who chose a course of treatment that ultimately resulted in death. Their choice was in part influenced by the prospect of the disfiguring surgery that would have been required for cure. In the first patient this would have meant massive head and neck surge...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Palliative care is one of the newer health specialties and continues to mature. While there has been remarkable progression of clinical skills and education, there has been a lack of focus on palliative care interdisciplinary leadership or development of leadership skills. This article highlights the importance of int...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：10.1177/0825859718791427
更新日期：2018-08-16 00:00:00
abstract：:In 2006, the Indian Health Service (IHS) and the National Cancer Institute (NCI) collaborated to develop an interdisciplinary palliative training program for health professionals in the Indian health system. Their goal was to improve clinician knowledge and skills in palliative care, to train future trainers, and to i...
journal_title：Journal of palliative care
pub_type： 杂志文章
doi：
更新日期：2010-04-01 00:00:00
abstract：:In 1992, 82.2% of deaths in Alberta occurred in acute care hospitals or continuing care facilities. This paper outlines the end-of-life care of adult inpatients who died that year in four such facilities (n = 137). CPR was an infrequent end-of-life treatment modality (2.9%), in stark contrast to the extensive use of o...
journal_title：Journal of palliative care
pub_type： 杂志文章,多中心研究
doi：
更新日期：1997-01-01 00:00:00
