Initiation of chemotherapy in cancer patients with poor performance status: a population-based analysis.

Abstract:

OBJECTIVE:Practice guidelines indicate that patients who have months to weeks left to live should not be offered chemotherapy. We examined factors associated with clinician-reported poor performance status as determined by the Palliative Performance Scale (PPS) and subsequent initiation of intravenous (IV) chemotherapy in an ambulatory cancer population in Ontario, Canada. METHODS:In this retrospective study, patients who had at least one PPS assessment indicating poor performance status (a PPS score of 50 or lower) comprised the study cohort. Using linked administrative databases, we observed the cohort for initiation of IV chemotherapy within 30 days of the first (index) poor PPS assessment. RESULTS:We excluded patients for whom IV or oral chemotherapy was ongoing or recently completed or whose performance status improved following the index assessment. Of the remaining cohort, 9.3 percent (264/2,842) received IV chemotherapy within 30 days of the index PPS. CONCLUSION:A small number of cancer patients with poor performance status began IV chemotherapy in the month following assessment.

journal_name

J Palliat Care

authors

Porter J,Earle C,Atzema C,Liu Y,Howell D,Seow H,Sutradhar R,Dudgeon D,Husain A,Sussman J,Barbera L

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

166-72

issue

3

eissn

0825-8597

issn

2369-5293

journal_volume

30

pub_type

杂志文章
  • Advanced Cancer Patients' Perceptions of Dignity: The Impact of Psychologically Distressing Symptoms and Preparatory Grief.

    abstract:PURPOSE:The present study assesses the relationship between patient dignity in advanced cancer and the following variables: psychological distress, preparatory grief, and sociodemographic and clinical characteristics. METHODS:The sample consisted of 120 patients with advanced cancer. The self-administered questionnair...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/0825859718759882

    authors: Kostopoulou S,Parpa E,Tsilika E,Katsaragakis S,Papazoglou I,Zygogianni A,Galanos A,Mystakidou K

    更新日期:2018-04-01 00:00:00

  • What about odor in terminal cancer?

    abstract::Daily care involving proximity with a malodorous patient in the terminal stage of cancer has often proved difficult for the caregiver. Whatever the cause of the primary cancer, three sources of noxious odor can exist or coexist: necrosis, superinfection, and perspiration and/or discharge. The proposed treatment calls ...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Jacob MJ,Markstein C,Liesse MM,Deckers C

    更新日期:1991-01-01 00:00:00

  • Caregiver bereavement outcome: relationship with hospice at home, satisfaction with care, and home death.

    abstract::This study used a randomized controlled trial design to investigate the impact of hospice at home (HAH) on caregiver bereavement outcome. Secondary analyses considered the association between bereavement, place of death, and carers' assessment of support. Ninety-six informal carers of patients referred to HAH were sur...

    journal_title:Journal of palliative care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Grande GE,Farquhar MC,Barclay SI,Todd CJ

    更新日期:2004-07-01 00:00:00

  • Inpatient Palliative Care Consultations From a Canadian Clinical Teaching Unit: Who is Referred and When?

    abstract::Inpatient palliative care consultation has been demonstrated to improve quality of life as well as decrease hospital readmissions, intensive care unit transfers, and hospital costs for people with a life limiting illness. The clinical teaching units (CTUs) at London Health Sciences Centre (LHSC) routinely admit patien...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/0825859718781363

    authors: Maddison AR,Malik S,Smaggus A

    更新日期:2018-10-01 00:00:00

  • Physician-Assisted Suicide and Euthanasia: Emerging Issues From a Global Perspective.

    abstract::Medical professional societies have traditionally opposed physician-assisted suicide and euthanasia (PAS-E), but this opposition may be shifting. We present 5 reasons why physicians shouldn't be involved in PAS-E. 1. Slippery slopes: There is evidence that safeguards in the Netherlands and Belgium are ineffective and ...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/0825859718777325

    authors: Sprung CL,Somerville MA,Radbruch L,Collet NS,Duttge G,Piva JP,Antonelli M,Sulmasy DP,Lemmens W,Ely EW

    更新日期:2018-10-01 00:00:00

  • Predicting family caregiver psychosocial functioning in palliative care.

    abstract:BACKGROUND:Health professionals are expected to support family caregivers of patients requiring palliative care. However, there is a dearth of empirical evidence to help clinicians identify caregivers who might be at risk of poor psychosocial functioning. PURPOSE:This secondary analysis of baseline data from a larger ...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Hudson PL,Hayman-White K,Aranda S,Kristjanson LJ

    更新日期:2006-10-01 00:00:00

  • Cancer pain control in Africa (state of the art).

    abstract::There may be quantitatively more cancer in the developing world, Africa included, than in the developed world. Unlike in the developed world, cancer patients in Africa present for treatment at a late stage and therefore most of them have pain. Yet, the most commonly used modality for treatment of the cancer pain is dr...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Minja BM

    更新日期:1989-06-01 00:00:00

  • Palliative Care Leadership.

    abstract::Palliative care is one of the newer health specialties and continues to mature. While there has been remarkable progression of clinical skills and education, there has been a lack of focus on palliative care interdisciplinary leadership or development of leadership skills. This article highlights the importance of int...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/0825859718791427

    authors: Dahlin C,Coyne P,Goldberg J,Vaughan L

    更新日期:2018-08-16 00:00:00

  • Nebulized Vasopressin for the Control of Hematemesis and Hemoptysis in a Child With Recurrent, Refractory Stage III Burkitt Lymphoma.

    abstract:BACKGROUND:Bleeding occurs with some regularity at the end of life. Patients often endure fatigue, weakness, pain, dyspnea and anxiety. These symptoms are magnified in visually apparent bleeds. Management can be particularly challenging as we attempt to balance therapies with goals of care. Children are at risk for suc...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/0825859719883844

    authors: Dulin JD,Coyne PJ

    更新日期:2020-04-01 00:00:00

  • Volunteers in palliative care make a difference.

    abstract::Family care giving is important for the quality of life of terminally ill patients and their family members. Although family caregivers are generally eager to provide palliative care, at some point it may become too demanding, and then volunteers can make a difference. This four-study paper presents the experiences of...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Luijkx KG,Schols JM

    更新日期:2009-04-01 00:00:00

  • Healthcare Needs of Patients with Amyotrophic Lateral Sclerosis (ALS) in Singapore: A patient-centred qualitative study from multiple perspectives.

    abstract:BACKGROUND:One challenge for those who manage amyotrophic lateral sclerosis (ALS) is to understand patients' needs. AIM:The aim of this study was to examine the needs of Singapore ALS patients from their perspective as well as that of their caregivers and healthcare professionals in order to develop a template for bet...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/082585971503100304

    authors: Ang K,Umapathi T,Tong J,Ng J,Tseng LJ,Woo IM

    更新日期:2015-01-01 00:00:00

  • Bad news for the patient and the family? The worst part of being a health care professional.

    abstract::In Spain, there is a general tendency to conceal the prognosis from a terminally ill patient. We conducted grounded-theory-based, phenomenological, qualitative research on this using a final sample of 42 in-depth interviews with doctors and nurses from different fields. We found that most health professionals believe ...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Schmidt Rio-Valle J,García Caro MP,Montoya Juarez R,Prados Peña D,Muñoz Vinuesa A,Pappous A,Cruz Quintana F

    更新日期:2009-10-01 00:00:00

  • Relational messages of control in nurse-patient interactions with terminally ill patients with AIDS and cancer.

    abstract::When dying patients are young adults or have a contagious disease, nursing staff may feel acutely uncomfortable and the patients may become isolated and alone. Nurses who work in palliative care units (PCU) develop special interactive skills that are generally acknowledged but not clearly defined or understood. Admiss...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Pepler CJ,Lynch A

    更新日期:1991-04-01 00:00:00

  • Advance Care Planning in Chinese Seniors: Cultural Perspectives.

    abstract::In traditional Chinese culture, death was sensitive and mentioning it was sacrilegious and to be avoided. Many Chinese families object to telling the patient a "bad" diagnosis or prognosis, which may hinder the chance in advance care planning (ACP) discussion. While death remains an inevitable consequence of being bor...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/0825859718763644

    authors: Cheng HWB

    更新日期:2018-10-01 00:00:00

  • Life-Sustaining Procedures, Palliative Care Consultation, and Do-Not Resuscitate Status in Dying Patients With COPD in US Hospitals: 2010-2014.

    abstract:AIM:Little is known regarding the extent to which dying patients with chronic obstructive pulmonary disease (COPD) receive life-sustaining procedures and palliative care in US hospitals. We examined temporal trends and the impact of palliative care on the use of life-sustaining procedures in this population. MATERIALS...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/0825859718777375

    authors: Shen JJ,Ko E,Kim P,Kim SJ,Lee YJ,Lee JH,Yoo JW

    更新日期:2018-07-01 00:00:00

  • New perspectives in the treatment of decubitus ulcers.

    abstract::Although the consequences of prolonged lying on a hard surface are as old as the human race, publications on this subject are scarce. This is due to the fact that a decubitus ulcer never occurs in isolation but is nearly always a complication of some other condition. The term "decubitus" was already used by Hildnaus i...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Guggisberg E,Terumalai K,Carron JM,Rapin CH

    更新日期:1992-07-01 00:00:00

  • Communication about palliative care for patients with chronic obstructive pulmonary disease.

    abstract::Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality and disability worldwide. For many patients, maximal therapy for COPD produces only modest relief of disabling symptoms and these symptoms result in a significantly reduced quality of life. Despite the high morbidity and mortality, patients w...

    journal_title:Journal of palliative care

    pub_type: 杂志文章,评审

    doi:

    authors: Curtis JR,Engelberg RA,Wenrich MD,Au DH

    更新日期:2005-10-01 00:00:00

  • Addressing myths about end-of-life care: research into the use of acute care hospitals over the last five years of life.

    abstract::Despite very little confirming evidence, one of the most pervasive beliefs about dying is that terminally ill people receive a great deal of health care in the last few days, weeks, or months of life. A secondary analysis of 1992/93 through 1996/97 Alberta inpatient hospital abstracts data was undertaken to explore an...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Wilson DM,Truman CD

    更新日期:2002-04-01 00:00:00

  • Integration of palliative care with alternative medicine in patients who have refused curative cancer therapy: a report of two cases.

    abstract::This article describes two young, potentially curable patients who chose a course of treatment that ultimately resulted in death. Their choice was in part influenced by the prospect of the disfiguring surgery that would have been required for cure. In the first patient this would have meant massive head and neck surge...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Jenkins CA,Scarfe A,Bruera E

    更新日期:1998-01-01 00:00:00

  • Living fully in the shadow of mortal time: psychosocial assets in advanced cancer.

    abstract:OBJECTIVE:This study aimed to characterize the strategies and psychosocial conditions that influence how resilient people live in the face of advanced cancer. METHODS:Grounded theory interviews and a survey of 10 resilient people with advanced cancer were collected and analyzed. FINDINGS:Personal assets - including p...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Wise M,Marchand L

    更新日期:2013-07-01 00:00:00

  • Paramedics' perceptions of their role in palliative care: analysis of focus group transcripts.

    abstract::Paramedics play an important role in out-of-hospital health care. They provide unscheduled care, assisting both patients with minor injuries and those experiencing life-threatening emergencies. Increasingly, paramedics are called on to manage chronic and complex health needs, including symptom relief for patients at t...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Lord B,Récoché K,O'Connor M,Yates P,Service M

    更新日期:2012-04-01 00:00:00

  • Would You Be Surprised if This Patient Died in the Next 12 Months? Using the Surprise Question to Increase Palliative Care Consults From the Emergency Department.

    abstract:BACKGROUND:There is a growing movement to increase palliative care consults from the emergency department (ED) to reduce healthcare costs and improve quality of life. The surprise question is a screening tool that emergency medicine physicians may be able to use towards achieving this goal. OBJECTIVE:The objectives of...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/0825859719866698

    authors: Zeng H,Eugene P,Supino M

    更新日期:2020-10-01 00:00:00

  • What Is Good Advance Care Planning According to Hospitalized Palliative Patients and Their Families? An Explorative Study.

    abstract:BACKGROUND:Advance care planning is not well implemented in Belgian hospital practice. In order to obtain successful implementation, implementation theory states that the adopters should be involved in the implementation process. This information can serve as a basis for creating better implementation strategies. AIM:...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:10.1177/0825859720938583

    authors: Vanderhaeghen B,Bossuyt I,Menten J,Rober P

    更新日期:2020-10-01 00:00:00

  • Within the Circle of Care: patient experiences of receiving palliative care.

    abstract::This paper presents an overview of a qualitative study of six recently discharged hospice patients, who had experienced at least two episodes of inpatient palliative care and who were interviewed about their experience of care. The resulting data formed a representation--the Circle of Care--with a central theme being ...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: McKinlay EM

    更新日期:2001-04-01 00:00:00

  • Pediatric palliative care education for medical students: development and evaluation of a pilot program.

    abstract:UNLABELLED:In Poland, medical curricula cover palliative care for adults, not for children. This paper evaluates feedback of students who participated in a pilot pediatric palliative care education program. METHOD:An anonymous questionnaire was designed for the students; they were asked to assess each aspect of the pr...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Korzeniewska-Eksterowicz A,Kedzierska B,Cynker-McCarthy M,Przysło Ł,Stolarska M,Nowicki GF,Młynarski W

    更新日期:2012-01-01 00:00:00

  • Evaluation of bereavement anniversary cards.

    abstract::The anniversary of a death is perceived as a difficult time by the majority of closely bereaved relatives and friends. Bereavement anniversary cards are supportive and useful in the context of wider follow-up. This study identified no strong predictors to indicate those for whom such a card would be inappropriate. Sev...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Hutchison SM

    更新日期:1995-10-01 00:00:00

  • The effectiveness and adverse effects profile of "burst" ketamine in refractory cancer pain: The VCOG PM 1-00 study.

    abstract::This multi-centre study of adjuvant "burst" ketamine in palliative care in-patients documents its effectiveness, duration of pain relief, and adverse effects (AE) profile. Patients received a three-to-five day continuous subcutaneous infusion (CSCI) of ketamine escalated from 100 to 300 to 500 mg/24 hours if required....

    journal_title:Journal of palliative care

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Jackson K,Ashby M,Howell D,Petersen J,Brumley D,Good P,Pisasale M,Wein S,Woodruff R

    更新日期:2010-10-01 00:00:00

  • Music therapy with persons who are indigent and terminally ill.

    abstract::This paper addresses the music therapy process specific to one subgroup of the general population identified as having terminal illness. This subgroup includes individuals who are impoverished, homeless, and do not have someone to provide them with care at the end of life. Based upon her clinical work at Malachi House...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Mramor KM

    更新日期:2001-10-01 00:00:00

  • Inpatient narcotic infusions for patients with cancer pain.

    abstract::Morphine and hydromorphone infusions of 6 or more (average 25.75) days in duration were used with increasing frequency (up to 7%) by our oncology inpatients. Eighty-six percent of the 135 inpatients we reviewed realized good pain control with dose rates up to 700 morphine-equivalent (ME) mg/h. Local toxicity occurred ...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Ferris FD,Kerr IG,De Angelis C,Sone M,Hume S

    更新日期:1990-07-01 00:00:00

  • Determinants of Oregon hospice chaplains' views on physician-assisted suicide.

    abstract:BACKGROUND:Although religiousness is a strong predictor of attitudes towards physician-assisted suicide (PAS), Oregon hospice chaplains express wide variation in their opposition to or support for legalized PAS. We explored factors associated with chaplains' views on PAS. METHODS:A mailed survey to chaplains from 51 O...

    journal_title:Journal of palliative care

    pub_type: 杂志文章

    doi:

    authors: Goy ER,Carlson B,Simopoulos N,Jackson A,Ganzini L

    更新日期:2006-07-01 00:00:00