Fibrinolytic enzyme in the lining walls of chronic subdural hematoma.

Abstract:

:Active plasmin, available plasmin, and total plasminogen were measured by Enzo-diffusion fibirn plate techniques in 11 cases and level of tissue activator and tissue fibrinolytic activities in another 11 cases with chronic subdural hematoma. The values were too small to be measured in some instances. Anti-plasmin in the hematoma was less than in the blood plasma. The outer membrane contained about three times more tissue activator than the dura mater, although the inner membrane contained none. Increased tissue activator, which exudes from the extremely vascular outer membrane, transforms plasminogen into plasmin in subdural hematoma, so that plasmin breaks down fibrin and fibrinogen and induces continuous hemorrhage.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Ito H,Komai T,Yamamoto S

doi

10.3171/jns.1978.48.2.0197

subject

Has Abstract

pub_date

1978-02-01 00:00:00

pages

197-200

issue

2

eissn

0022-3085

issn

1933-0693

journal_volume

48

pub_type

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