History of neurosurgery at University of Toronto: the St. Michael's story.

abstract：OBJECT:Age-related macular degeneration (AMD) is the leading cause of severe vision loss in people older than age 65 years in the western world. The visual acuity loss usually results from the ingrowth of new vessels from the choroid capillaries, so called choroidal neovascularization (CNV). The aim of this pilot study...

journal_title：Journal of neurosurgery

authors： Haas A,Papaefthymiou G,Langmann G,Schröttner O,Feigl B,Leber KA,Hanselmayer R,Pendl G

更新日期：2000-12-01 00:00:00

abstract：OBJECT:The authors studied the microsurgical anatomy of the ophthalmic artery (OphA), paying particular attention to its possibly dangerous anastomoses with the middle meningeal artery (MMA). METHODS:The microsurgical anatomy of the OphA and its anastomoses with the MMA were studied in 14 vessels from seven adult cada...

journal_title：Journal of neurosurgery

authors： Perrini P,Cardia A,Fraser K,Lanzino G

更新日期：2007-01-01 00:00:00

abstract：OBJECT:The human leukocyte antigen-A24 (HLA-A24) allele is highly expressed in Asians. This allele is expressed in 60% of the Japanese population and in a significant number of people of other ethnicities. The interleukin-13 type alpha2 receptor (IL-13Ralpha2) has been shown to be a glioma-specific antigen, and is abun...

journal_title：Journal of neurosurgery

authors： Shimato S,Natsume A,Wakabayashi T,Tsujimura K,Nakahara N,Ishii J,Ito M,Akatsuka Y,Kuzushima K,Yoshida J

更新日期：2008-07-01 00:00:00

abstract：OBJECT:Congenital occipitocervical (OC) instability is uncommon in healthy children but can occur in many children with Down syndrome. A simple morphometric method of evaluating the OC joint in children with OC instability is presented, supported by a qualitative image analysis based on computed tomography (CT). METHO...

journal_title：Journal of neurosurgery

authors： Browd S,Healy LJ,Dobie G,Johnson JT 3rd,Jones GM,Rodriguez LF,Brockmeyer DL

更新日期：2006-07-01 00:00:00

abstract：OBJECT:Atorvastatin, a beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitor, has pleiotropic effects, such as promoting angiogenesis, increasing fibrinolysis, and reducing inflammatory responses, and has shown promise in enhancing recovery in animals with traumatic brain injury (TBI) and stroke. The authors ...

journal_title：Journal of neurosurgery

authors： Lu D,Mahmood A,Goussev A,Schallert T,Qu C,Zhang ZG,Li Y,Lu M,Chopp M

更新日期：2004-11-01 00:00:00

abstract：OBJECT:Intraoperative neurophysiological monitoring (IONM) represents an established tool in neurosurgery to increase patient safety. Its application, however, is controversial. Its use has been described as helpful in avoiding neurological deterioration during intracranial aneurysm surgery. Its impact on extracranial-...

journal_title：Journal of neurosurgery

authors： Dengler J,Cabraja M,Faust K,Picht T,Kombos T,Vajkoczy P

更新日期：2013-07-01 00:00:00

abstract：OBJECT:The goal of this study was to assess the accuracy of the routine clinical use of transcranial Doppler (TCD) ultrasonography and SPECT in predicting angiographically demonstrated vasospasm. METHODS:Following receipt of institutional review board approval, the authors reviewed the records of patients with subarac...

journal_title：Journal of neurosurgery

authors： Kincaid MS,Souter MJ,Treggiari MM,Yanez ND,Moore A,Lam AM

更新日期：2009-01-01 00:00:00

abstract：OBJECT:The authors discuss the indications for and timing of a diagnostic neurosurgical procedure in children with diabetes insipidus (DI) and a thickened pituitary stalk (TPS) on magnetic resonance (MR) imaging. METHODS:Seven children with a TPS who presented with DI eventually underwent surgery for diagnostic purpos...

journal_title：Journal of neurosurgery

authors： Beni-Adani L,Sainte-Rose C,Zerah M,Brunelle F,Constantini S,Renier D,Lellouch-Tubiana A,Leger J,Pierre-Kahn A

更新日期：2005-08-01 00:00:00

abstract：:OBJECTIVE Arteriovenous malformations (AVMs) in the cerebellopontine angle cistern (CPAC) are specific lesions that can cause neurovascular compression syndromes as well as intracranial hemorrhage. Although case reports describing the CPAC AVMs, especially those presenting with trigeminal neuralgia (TN), have been acc...

journal_title：Journal of neurosurgery

authors： Nishino K,Hasegawa H,Morita K,Fukuda M,Ito Y,Fujii Y,Sato M

更新日期：2017-01-01 00:00:00

abstract：OBJECT:Preoperative clinical risk classification of carotid artery (CA) stenosis anticipates the outcome of CA intervention. A higher incidence of neurological morbidity was noted after CA stenting (CAS) in patients with medical risks than in those without risks. However, little is known about the correlation between c...

journal_title：Journal of neurosurgery

authors： Hao H,Iihara K,Ishibashi-Ueda H,Saito F,Hirota S

更新日期：2011-04-01 00:00:00

abstract：:In patients with vein of Galen malformations, high-flow shunting decreases cerebral perfusion. By reducing or eliminating these shunts, transarterial embolization can improve cerebral perfusion and clinical outcomes. Quantifying pre- and postembolization shunt blood flow may help determine the optimal timing and effic...

journal_title：Journal of neurosurgery

authors： Langer DJ,Song JK,Niimi Y,Chwajol M,Lefton DR,Brisman JL,Molofsky W,Kupersmith MJ,Berenstein A

更新日期：2006-01-01 00:00:00

abstract：:In the central nervous system, recurrence of intracranial Masson's vegetant intravascular hemangioendothelioma (MVIH) is rare. To the authors' knowledge, only three recurrent intracranial cases have been reported. The authors report the case of a 75-year-old woman with a recurrent left-sided cerebellopontine angle and...

journal_title：Journal of neurosurgery

authors： Avellino AM,Grant GA,Harris AB,Wallace SK,Shaw CM

更新日期：1999-08-01 00:00:00

abstract：:The pressure-volume index (PVI) was measured in six adult cats while cerebral perfusion pressure (CPP) was reduced from normal levels to below the autoregulatory range by a continuous infusion of adenosine triphosphate. Anesthesia was induced with methohexital and maintained with an N2O:O2 (70%:30%) mixture. Body temp...

journal_title：Journal of neurosurgery

authors： Gray WJ,Rosner MJ

更新日期：1987-09-01 00:00:00

abstract：OBJECT:Neurocognitive performance is used to assess multiple cognitive domains, including motor coordination, before and after carotid endarterectomy (CEA). Although gross motor strength is impaired with ischemia of large cortical areas or of the internal capsule, the authors hypothesize that patients undergoing CEA de...

journal_title：Journal of neurosurgery

authors： Heyer EJ,Mallon KA,Mergeche JL,Stern Y,Connolly ES

更新日期：2015-01-01 00:00:00

abstract：OBJECT:Resection of cancer and the involved artery in the neck has been applied with some success, but the indications for such an aggressive approach at the skull base are less well defined. The authors therefore evaluated the outcomes of advanced skull base malignancies in patients who were treated with bypass and re...

journal_title：Journal of neurosurgery

authors： Kalani MY,Kalb S,Martirosyan NL,Lettieri SC,Spetzler RF,Porter RW,Feiz-Erfan I

更新日期：2013-03-01 00:00:00

abstract：:Intracranial arteriovenous malformations (AVM's) have been classified as pure pial, pure dural, and mixed pial and dural. Dural AVM's are relatively uncommon, with 377 cases documented up to 1990. These lesions were believed to be situated within the walls of the sinuses, but during the last decade researchers discove...

journal_title：Journal of neurosurgery

authors： Malik GM,Mahmood A,Mehta BA

更新日期：1994-10-01 00:00:00

abstract：:The authors studied the effect of high cervical cord section on the phenomenon of autoregulation in the rhesus monkey with the hydrogen clearance method to measure focal spinal cord blood flow (SCBF). Laminectomies were performed at T7-11 and C1-2. The spinal cord was completely severed at C1-2. Under normocapnic cond...

journal_title：Journal of neurosurgery

authors： Kobrine AI,Doyle TF,Newby N,Rizzoli HV

更新日期：1976-04-01 00:00:00

abstract：:Levels of protein kinase C (PKC) isoforms in eight human glioblastoma cell lines and two normal human glial cell cultures were determined. Earlier studies identified PKC-alpha and PKC-gamma in these cell lines but PKC-beta was not present. In this study, PKC-epsilon and PKC-zeta are demonstrated immunologically in the...

journal_title：Journal of neurosurgery

authors： Xiao H,Goldthwait DA,Mapstone T

更新日期：1994-11-01 00:00:00

abstract：:High-resolution dynamic infrared (DIR) imaging provides intraoperative real-time physiological, anatomical, and pathological information; however, DIR imaging has rarely been used in neurosurgical patients. The authors report on their initial experience with intraoperative DIR imaging in 30 such patients. A novel, lon...

journal_title：Journal of neurosurgery

authors： Ecker RD,Goerss SJ,Meyer FB,Cohen-Gadol AA,Britton JW,Levine JA

更新日期：2002-12-01 00:00:00

abstract：:OBJECTIVECerebrovascular bypass surgery is a challenging yet important neurosurgical procedure that is performed to restore circulation in the treatment of carotid occlusive diseases, giant/complex aneurysms, and skull base tumors. It requires advanced microsurgical skills and dedicated training in microsurgical techn...

journal_title：Journal of neurosurgery

authors： Cikla U,Sahin B,Hanalioglu S,Ahmed AS,Niemann D,Baskaya MK

更新日期：2018-05-11 00:00:00

abstract：:A feasibility study reveals that a standard linear accelerator, with only slight modification, can function in a manner similar to Leksell's multiple cobalt radiation device. A high radiation dose can be delivered to a 1-cm or 0.5-cm volume target with insignificant radiation effect on the surrounding tissue. ...

journal_title：Journal of neurosurgery

authors： Heifetz MD,Wexler M,Thompson R

更新日期：1984-04-01 00:00:00

abstract：:In preparing this paper, the authors reviewed their experiences with four cases of T1-2 disc herniation as well as the medical literature on the subject. Intervertebral thoracic disc herniations are uncommon and high thoracic disc herniations are rare. In the upper third of the thoracic spine, T1-2 is the most common ...

journal_title：Journal of neurosurgery

authors： Morgan H,Abood C

更新日期：1998-01-01 00:00:00

abstract：:Traction injury to the optic nerve and vasa nervorum is the suggested etiology for monocular blindness following trivial frontal trauma. Holographic interferometry was used on human skulls to demonstrate orbital deformation in response to nondestructive frontal loading. The findings suggest an additional mechanism for...

journal_title：Journal of neurosurgery

authors： Gross CE,DeKock JR,Panje WR,Hershkowitz N,Newman J

更新日期：1981-12-01 00:00:00

abstract：OBJECT:It is unclear if there is a relationship between Chiari malformation Type I (CM-I) and body mass index (BMI). The aim of this study was to identify the relationship between BMI and cerebellar tonsil position in a random sample of people. METHODS:Cerebellar tonsil position in 2400 subjects from a cohort of patie...

journal_title：Journal of neurosurgery

authors： Smith BW,Strahle J,Kazarian E,Muraszko KM,Garton HJ,Maher CO

更新日期：2015-07-01 00:00:00

abstract：:An extraosseous extradural tumor of the lumbar region with the histological appearance of chordoma produced symptoms in a 58-year-old woman. The tumor occupied the epidural space and produced scalloping of the adjacent vertebral body and pedicle without associated bone destruction. The location of the tumor within Bat...

journal_title：Journal of neurosurgery

authors： Tomlinson FH,Scheithauer BW,Miller GM,Onofrio BM

更新日期：1991-12-01 00:00:00

abstract：OBJECT:This study was designed to evaluate the clinical and histopathological effects of long-term (3-month) intraventricular baclofen (IVB) infusion in beagle dogs. METHODS:Catheters were inserted stereotactically into the lateral ventricles of nine dogs and were connected to implanted Synchromed II pumps. Saline sol...

journal_title：Journal of neurosurgery

authors： Albright AL

更新日期：2007-09-01 00:00:00

abstract：:Subtemporal decompression is recognized as an effective treatment for slit-ventricle syndrome; however, the effects of this procedure have not been demonstrated using both pre- and postsurgical intracranial pressure (ICP) monitoring. The authors report two cases in which slit-ventricle syndrome and elevated ICP had be...

journal_title：Journal of neurosurgery

authors： Allan R,Chaseling R

更新日期：2004-11-01 00:00:00

abstract：:The author describes the history of neurosurgery in Manitoba, with particular emphasis on events that occurred after his arrival there in 1950. Highlights of global neurosurgery are spliced into the author's reminiscences to anchor the local history with that of neurosurgery as a whole. ...

journal_title：Journal of neurosurgery

authors： Parkinson D

更新日期：1995-05-01 00:00:00

abstract：:Intratumoral hemorrhage as the presenting symptom of spinal tumors is rare. The authors describe a patient who presented with rapidly progressing paraplegia 24 hours after sustaining a minor traumatic injury of the thoracic spine. Radiological evaluation demonstrated a low-thoracic intradural tumor that was resected a...

journal_title：Journal of neurosurgery

authors： Cohen ZR,Knoller N,Hadani M,Davidson B,Nass D,Ram Z

更新日期：2000-10-01 00:00:00

abstract：OBJECT:An approach toward the treatment of intracranial gliomas was developed in a rat experimental model. The authors investigated the ability of "professional" antigen-presenting cells (dendritic cells) to enhance host antitumor immune responses when injected as a vaccine into tumor-bearing animals. METHODS:Dendriti...

journal_title：Journal of neurosurgery

authors： Liau LM,Black KL,Prins RM,Sykes SN,DiPatre PL,Cloughesy TF,Becker DP,Bronstein JM

更新日期：1999-06-01 00:00:00