当前位置： SCI文献检索 > JOURNAL OF PSYCHIATRIC RESEARCH期刊下所有文献 > Duration of untreated psychosis may predict acute treatment response in first-episode schizophrenia.

Duration of untreated psychosis may predict acute treatment response in first-episode schizophrenia.

Abstract：

:There is growing evidence for a relationship between the duration of untreated psychosis (DUP) and the prognosis in schizophrenia. The objective of this study is to evaluate whether DUP and premorbid level of social functioning are related to treatment response in acute treatment of first-episode schizophrenia. Seventy-nine first-episode schizophrenia patients were assessed with BPRS, SAPS, and SANS on admission and discharge during their first hospitalisation. Percentage of the difference between admission and discharge in total scores of all scales were taken as measures of absolute symptom reduction. The median DUP was 6 months (mean=8.6). DUP was correlated with reduction in BPRS and SAPS scores but not SANS scores. Patients with a short DUP (n=41) also showed a higher reduction in BPRS, and SAPS scores than those with a long DUP. Premorbid Adjustment Scale (PAS) scores were inversely correlated with age at onset and positively correlated with BPRS scores at admission. We did not find any relationship between PAS scores and response to treatment. Our findings suggest that DUP may be an important predictor of response in acute treatment of first-episode schizophrenia and thus, attempts for early diagnosis may also have a positive effect on acute treatment response.

journal_name

J Psychiatr Res

journal_title

Journal of psychiatric research

authors

Uçok A,Polat A,Genç A,Cakir S,Turan N

doi

10.1016/s0022-3956(03)00104-3

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

163-8

issue

2

eissn

0022-3956

issn

1879-1379

pii

S0022395603001043

journal_volume

38

pub_type

杂志文章

相关文献

JOURNAL OF PSYCHIATRIC RESEARCH文献大全
  • The effects of early and sustained intervention on the long-term morbidity of schizophrenia.

    abstract：:By examining the literature concerning early intervention with antipsychotic medications, and how it affects long-term morbidity, this article will review the concept that early intervention with antipsychotic medications improves the long-term course of schizophrenia. It also looks at the potential long-term effects ...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,评审

    doi：10.1016/s0022-3956(97)00014-9

    authors： Wyatt RJ,Henter ID

    更新日期：1998-05-01 00:00:00

  • Comparison of generic and disease-specific measures of quality of life in first-episode psychosis.

    abstract：BACKGROUND:Quality of life (QOL) is now recognised as an important measure of outcome that could potentially influence clinical decision-making for those with a first-episode psychosis (FEP). A number of QOL instruments are available however; many differ in their conceptual orientation which may have serious implicatio...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2013.06.001

    authors： Renwick L,Lyne J,Owens E,O' Donoghue B,Madigan K,Turner N,Drennan J,Sheridan A,Kinsella A,Clarke M,O' Callaghan E

    更新日期：2013-10-01 00:00:00

  • Trait anxiety and the effect of a single high dose of diazepam in unipolar depression.

    abstract：:In this cross-sectional study we explored in 101 depressive in-patients (DSM III-R) the association between level of trait anxiety and variables that have been investigated previously to discern primary and secondary depression, respectively. Besides, we explored the influence of trait anxiety level on difference in t...

    journal_title：Journal of psychiatric research

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0022-3956(01)00035-8

    authors： Bruijn JA,Moleman P,van den Broek WW,Mulder PG

    更新日期：2001-11-01 00:00:00

  • Ascertaining psychiatric diagnoses with the family history method in a substance abuse population.

    abstract：:Research investigating patterns of familial aggregation of psychiatric disorders has used the family history method in which a single family member reports on the psychiatric history of their relatives. This method is more efficient and less costly than the family study method, in which direct interviews are performed...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/0022-3956(92)90005-9

    authors： Kosten TA,Anton SF,Rounsaville BJ

    更新日期：1992-04-01 00:00:00

  • A study of the neural correlates of episodic memory and HPA axis status in drug-free depressed patients and healthy controls.

    abstract：:Altered laterality of cortical activity, neuropsychological impairment and hypercortisolaemia have been shown in depression. The neural correlates of episodic memory in healthy subjects demonstrate hemispheric laterality but it is not known whether this is affected by depression and/or hypercortisolaemia. Twenty-seven...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2006.08.008

    authors： Alhaj HA,Massey AE,McAllister-Williams RH

    更新日期：2007-04-01 00:00:00

  • Microglia mediated neuroinflammation in autism spectrum disorder.

    abstract：BACKGROUND:Although the precise pathophysiologies underlying autism spectrum disorder (ASD) has not yet been fully clarified, growing evidence supports the involvement of neuroinflammation in the pathogenesis of this disorder, with microglia being particular relevance in the pathophysiologic processes. OBJECTIVE:The p...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,评审

    doi：10.1016/j.jpsychires.2020.07.013

    authors： Liao X,Yang J,Wang H,Li Y

    更新日期：2020-11-01 00:00:00

  • BDNF serum and CSF concentrations in Alzheimer's disease, normal pressure hydrocephalus and healthy controls.

    abstract：:Alzheimer's disease (AD) and normal pressure hydrocephalus (NPH) are common forms of dementia in the elderly. Recent findings have suggested an involvement of brain-derived neurotrophic factor (BDNF) in the pathogenesis of AD. BDNF is an endogenous protein involved in the maintenance of neuronal function, synaptic pla...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2006.01.014

    authors： Laske C,Stransky E,Leyhe T,Eschweiler GW,Maetzler W,Wittorf A,Soekadar S,Richartz E,Koehler N,Bartels M,Buchkremer G,Schott K

    更新日期：2007-08-01 00:00:00

  • Mediating effects of hair cortisol on the mutual association of job burnout and insomnia: A retrospective exploratory study.

    abstract：BACKGROUNDS:The present study was designed to clarify the mutual association of job burnout and insomnia and to detect the mediating effects of hair cortisol on that association. METHODS:In all, 68 female employees were recruited for the study from one secondary and one tertiary hospital between October 2018 and Novem...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2019.07.001

    authors： Wang C,Dai J,Li J

    更新日期：2019-10-01 00:00:00

  • Psychotic depression in hospitalized patients: Longitudinal outcomes of psychotic vs. nonpsychotic depression among inpatients.

    abstract：:Even though psychotic depression is related to worse outcomes than nonpsychotic depression, there is increasing evidence that this greater severity is not solely explained by the depressive symptoms. We evaluated the socio-demographic and clinical characteristics, as well as the differences in clinical outcomes of psy...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2020.06.002

    authors： Costa FBPD,Trachtenberg E,Boni A,Primo de Carvalho Alves L,Magalhães PVDS,Rocha NS

    更新日期：2020-10-01 00:00:00

  • Italian Multicentre Study on Dementia (SMID): a neuropsychological test battery for assessing Alzheimer's disease.

    abstract：:For the Italian Multicentre Study on Dementia, a longitudinal survey on Alzheimer's disease (AD) initiated in 1982, we developed a neuropsychological test battery for screening, staging and monitoring cognitive impairment in AD patients and for delineating their pattern of cognitive decline. The tests measured higher ...

    journal_title：Journal of psychiatric research

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/0022-3956(90)90011-e

    authors： Bracco L,Amaducci L,Pedone D,Bino G,Lazzaro MP,Carella F,D'Antona R,Gallato R,Denes G

    更新日期：1990-01-01 00:00:00

  • Dispositional gratitude and mental health in the U.S. veteran population: Results from the National Health and Resilience Veterans Study.

    abstract：:Dispositional gratitude may be linked to positive mental health outcomes, yet population-based data on this association are lacking. Military veterans are an ideal population in which to examine this question given high rates of psychiatric morbidities and efforts to promote psychological resilience in this population...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2021.01.020

    authors： McGuire AP,Fogle BM,Tsai J,Southwick SM,Pietrzak RH

    更新日期：2021-01-19 00:00:00

  • Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis.

    abstract：:Brain-derived neurotrophic factor (BDNF) plays a central role in synaptic plasticity and neurogenesis. Bipolar disorder (BD) is among the most disabling of all psychiatric disorders and is associated with poor outcomes. Some studies suggest that BDNF levels decrease during mood states and remain normal during euthymia...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jpsychires.2011.03.002

    authors： Fernandes BS,Gama CS,Ceresér KM,Yatham LN,Fries GR,Colpo G,de Lucena D,Kunz M,Gomes FA,Kapczinski F

    更新日期：2011-08-01 00:00:00

  • The emerging field of retinal electrophysiological measurements in psychiatric research: A review of the findings and the perspectives in major depressive disorder.

    abstract：:Major depressive disorder (MDD) is a severe mental illness leading to long-term disabilities. One of the current challenges in psychiatric research is to develop new approaches to investigate the pathophysiology of MDD and monitor drug response in order to provide better therapeutic strategies to the patients. Since t...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,评审

    doi：10.1016/j.jpsychires.2015.09.003

    authors： Schwitzer T,Lavoie J,Giersch A,Schwan R,Laprevote V

    更新日期：2015-11-01 00:00:00

  • From phone use to speeding and driving under influence: Identifying clusters of driving risk behaviors as an opportunity for targeted interventions.

    abstract：:Identifying the profile of risky behaviors among drivers is central to propose effective interventions. Due to the multidimensional and overlapping aspects of risky driving behaviors, cluster analysis can provide additional insights in order to identify specific subgroups of risk. This study aimed to identify clusters...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2020.11.025

    authors： Rabelo-da-Ponte FD,Scherer JN,Roglio V,Borges EN,Galland F,Sousa T,Passos IC,von Diemen L,Kessler F,Pechansky F

    更新日期：2020-11-12 00:00:00

  • Cognitive intrusion of pain and catastrophic thinking independently explain interference of pain in the activities of daily living.

    abstract：:Patients with musculoskeletal illness often report that pain interferes with their ability to engage in activities of daily living. Catastrophic thinking is consistently depicted as an important cognitive factor that hinders adjustment to pain. Current research has also shown that pain negatively impacts an individual...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2017.04.005

    authors： Talaei-Khoei M,Ogink PT,Jha R,Ring D,Chen N,Vranceanu AM

    更新日期：2017-08-01 00:00:00

  • Posttraumatic stress disorder and nonadherence to medications prescribed for chronic medical conditions: A meta-analysis.

    abstract：BACKGROUND:Patients with posttraumatic stress disorder (PTSD) are at increased risk for adverse consequences from comorbid medical conditions. Nonadherence to medications prescribed to treat those comorbid conditions may help explain this increased risk. We sought to determine the association between PTSD and medicatio...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jpsychires.2018.02.013

    authors： Taggart Wasson L,Shaffer JA,Edmondson D,Bring R,Brondolo E,Falzon L,Konrad B,Kronish IM

    更新日期：2018-07-01 00:00:00

  • The acute antipanic and anxiolytic activity of aerobic exercise in patients with panic disorder and healthy control subjects.

    abstract：:Regular physical activity is anxiolytic in both healthy subjects and patients with panic disorder. In contrast, acute exercise may induce acute panic attacks or increase subjective anxiety in patients with panic disorder more than in other people. The effects of quiet rest or an aerobic treadmill exercise (30 min at a...

    journal_title：Journal of psychiatric research

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jpsychires.2009.02.004

    authors： Ströhle A,Graetz B,Scheel M,Wittmann A,Feller C,Heinz A,Dimeo F

    更新日期：2009-08-01 00:00:00

  • Prevalence of psychiatric morbidity and psychological adaptation of the nurses in a structured SARS caring unit during outbreak: a prospective and periodic assessment study in Taiwan.

    abstract：:To assess the rapidly changing psychological status of nurses during the acute phase of the 2003 SARS outbreak, we conducted a prospective and periodic evaluation of psychiatric morbidity and psychological adaptation among nurses in SARS units and non-SARS units. Nurse participants were from two SARS units (regular SA...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2005.12.006

    authors： Su TP,Lien TC,Yang CY,Su YL,Wang JH,Tsai SL,Yin JC

    更新日期：2007-01-01 00:00:00

  • Early discontinuation of pharmacotherapy in U.S. veterans diagnosed with PTSD and the role of psychotherapy.

    abstract：:More than 50% of individuals who enter treatment for posttraumatic stress disorder (PTSD) are prescribed a psychotropic medication. To date, however, data are limited regarding the prevalence and determinants of discontinuation of psychotropic medication in this population. To address this gap, we analyzed data from 1...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2020.10.005

    authors： Duek O,Pietrzak RH,Petrakis I,Hoff R,Harpaz-Rotem I

    更新日期：2021-01-01 00:00:00

  • Working memory dysfunction in obsessive-compulsive disorder: a neuropsychological and functional MRI study.

    abstract：:Previous neuropsychological studies indicate that OCD subtypes such as checking rituals might be associated with a working memory deficit. On the other hand, functional neuroimaging studies found functional abnormalities of the frontal cortex and subcortical structures in OCD. Combined with functional imaging method, ...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2008.10.013

    authors： Nakao T,Nakagawa A,Nakatani E,Nabeyama M,Sanematsu H,Yoshiura T,Togao O,Tomita M,Masuda Y,Yoshioka K,Kuroki T,Kanba S

    更新日期：2009-05-01 00:00:00

  • READMIT: a clinical risk index to predict 30-day readmission after discharge from acute psychiatric units.

    abstract：:Our aim was to create a clinically useful risk index, administered prior to discharge, for determining the probability of psychiatric readmission within 30 days of hospital discharge for general psychiatric inpatients. We used population-level sociodemographic and health administrative data to develop a predictive mod...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2014.12.003

    authors： Vigod SN,Kurdyak PA,Seitz D,Herrmann N,Fung K,Lin E,Perlman C,Taylor VH,Rochon PA,Gruneir A

    更新日期：2015-02-01 00:00:00

  • Persecutory ideation and anomalous perceptual experiences in the context of the COVID-19 outbreak in France: what's left one month later?

    abstract：PURPOSE:Beyond the effects of the coronavirus pandemic on the public's health, the length of lockdown and its possible psychological impacts on populations is heavily debated. However, the consequences of lockdown on psychotic symptoms have been poorly investigated. METHODS:An online survey was run from April 13 to Ma...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2020.12.042

    authors： Bortolon C,Capdevielle D,Dubreucq J,Raffard S

    更新日期：2020-12-21 00:00:00

  • Interpersonal problems associated with narcissism among psychiatric outpatients.

    abstract：:Narcissistic personality disorder is the subject of extensive discussion in the literature. Yet, the validity of this diagnostic category remains questionable. This is owed, in large part, to the relative absence of empirical work that has examined narcissism in clinical samples. Descriptions and findings from studies...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2008.12.005

    authors： Ogrodniczuk JS,Piper WE,Joyce AS,Steinberg PI,Duggal S

    更新日期：2009-06-01 00:00:00

  • Impact of perceived rearing and social support on bonding failure and depression among mothers: A longitudinal study of pregnant women.

    abstract：BACKGROUND:Although previous studies have reported associations between bonding failure, depression, social support among mothers, and perceived rearing, the causal relationships remain unclear. METHODS:A total of 855 women (mean age, 32.4 ± 4.4 years) completed the Mother-Infant Bonding Questionnaire (MIBQ), the Edin...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2018.09.001

    authors： Ohara M,Nakatochi M,Okada T,Aleksic B,Nakamura Y,Shiino T,Yamauchi A,Kubota C,Morikawa M,Murase S,Goto S,Kanai A,Kato R,Ando M,Ozaki N

    更新日期：2018-10-01 00:00:00

  • Early symptom change and prediction of subsequent remission with olanzapine augmentation in divalproex-resistant bipolar mixed episodes.

    abstract：:Potential predictors of remission in mixed bipolar I disorder were identified using early Clinical Global Impression-Severity (CGI-S) improvement criteria in divalproex-resistant patients randomized to olanzapine augmentation (olanzapine + divalproex; N = 101) in a 6-week, double-blind, placebo-controlled trial. In a ...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jpsychires.2010.05.016

    authors： Houston JP,Ketter TA,Case M,Bowden C,Degenhardt EK,Jamal HH,Tohen M

    更新日期：2011-02-01 00:00:00

  • Measuring resilience in women experiencing infertility using the CD-RISC: examining infertility-related stress, general distress, and coping styles.

    abstract：:Psychological morbidity concurrent with fertility problems has been the focus of substantial scientific inquiry. However, researchers have largely overlooked psychological resilience within this population. This study explored the associations between resilience, infertility-related and general distress, and coping be...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jpsychires.2009.06.007

    authors： Sexton MB,Byrd MR,von Kluge S

    更新日期：2010-03-01 00:00:00

  • Transcutaneous electrical acupoint stimulation as an adjunct therapy for obsessive-compulsive disorder: A randomized controlled study.

    abstract：BACKGROUND:Transcutaneous electrical acupoint stimulation (TEAS) is thought to have potential to treat obsessive-compulsive disorder (OCD). OBJECTIVE:The purpose of this study was to determine whether adding TEAS to cognitive behavioral therapy (CBT) and clomipramine would improve the efficacy of these conventional tr...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jpsychires.2016.05.015

    authors： Feng B,Zhang ZJ,Zhu RM,Yuan GZ,Luo LY,McAlonan GM,Xu FZ,Chen J,Liu LY,Lv YY,Wong HK,Zhang Y,Zhu LX

    更新日期：2016-09-01 00:00:00

  • ADHD and executive functioning deficits in OCD youths who hoard.

    abstract：:Hoarding is common among youth with obsessive compulsive disorder (OCD), with up to 26% of OCD youth exhibiting hoarding symptoms. Recent evidence from adult hoarding and OCD cohorts suggests that hoarding symptoms are associated with executive functioning deficits similar to those observed in subjects with attention ...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jpsychires.2016.07.024

    authors： Park JM,Samuels JF,Grados MA,Riddle MA,Bienvenu OJ,Goes FS,Cullen B,Wang Y,Krasnow J,Murphy DL,Rasmussen SA,McLaughlin NC,Piacentini J,Pauls DL,Stewart SE,Shugart YY,Maher B,Pulver AE,Knowles JA,Greenberg BD,Fyer

    更新日期：2016-11-01 00:00:00

  • Functional connectivity of the temporo-parietal region in schizophrenia: effects of rTMS treatment of auditory hallucinations.

    abstract：:Auditory-verbal hallucinations are a hallmark symptom of schizophrenia. In recent years, repetitive transcranial magnetic stimulation (rTMS) targeting speech perception areas has been advanced as a potential treatment of medication-resistant hallucinations. However, the underlying neural processes remain unclear. This...

    journal_title：Journal of psychiatric research

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jpsychires.2009.12.011

    authors： Vercammen A,Knegtering H,Liemburg EJ,den Boer JA,Aleman A

    更新日期：2010-08-01 00:00:00

  • Narcissistic Personality Disorder and suicidal behavior in mood disorders.

    abstract：:The relationship of Narcissistic Personality Disorder (NPD) to suicidal behavior is understudied. The modest body of existing research suggests that NPD is protective against low-lethality suicide attempts, but is associated with high lethality attempts. Mood-disordered patients (N = 657) received structured interview...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2016.10.020

    authors： Coleman D,Lawrence R,Parekh A,Galfalvy H,Blasco-Fontecilla H,Brent DA,Mann JJ,Baca-Garcia E,Oquendo MA

    更新日期：2017-02-01 00:00:00