Platinum and palladium complexes containing ethylenediamine derivatives as carrier ligands and their antitumor activity.

Abstract:

:We prepared new antitumor active platinum complexes containing N,N'-bis(2-chloroethyl)ethylenediamine (ClEn) as an alkylating carrier ligand in order to obtain increased antitumor effects. Some of the platinum complexes synthesized showed enhanced antitumor activity. However, palladium(II) complexes containing ClEn were inactive against L1210 and P388.

authors

Lee K,Tashiro T,Noji M

doi

10.1248/cpb.42.702

subject

Has Abstract

pub_date

1994-03-01 00:00:00

pages

702-3

issue

3

eissn

0009-2363

issn

1347-5223

journal_volume

42

pub_type

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