Magnetic resonance imaging evaluation of pulmonary vascular malformations.

Abstract:

OBJECTIVE:The purpose of our study was to establish magnetic resonance imaging (MRI) criteria for the diagnosis of pulmonary vascular malformations (PVMs). MATERIALS AND METHODS:Since 1987, 11 patients have been referred for chest MRI at our institution because of findings suggestive of a PVM. They were evaluated with a 1.5-T MRI system, incorporating a combination of spin-echo, gradient-recalled echo (GRE) cine, and 2-D phase contrast (PC) cine sequences. We used the following MRI criteria to diagnose PVM: (1) flow void or intermediate gray signal on spine-echo sequences; (2) bright signal on GRE cine sequences; and (3) bright signal consistent with flow detected on PC cine sequences using relatively low velocity ranges. Twelve patients not suspected of having a PVM served as controls; all had both MRI and pulmonary angiography to evaluate for central pulmonary embolus. RESULTS:Eight patients in the study group had PVM as determined with MRI using these criteria. In four of these patients, a PVM was confirmed by subsequent pulmonary angiography. Three patients did not have PVM utilizing these criteria; two had neoplasms and one had presumed mucus plugging and/or atelectasis that resolved spontaneously. The smallest vascular malformation detected by MRI was 1 cm. None of the control patients had PVM by MRI or pulmonary angiography. CONCLUSION:Utilizing these criteria, we believe that MRI is potentially an excellent noninvasive modality to evaluate PVM, and we stress that some form of PC cine sequence must be performed to determine if indeed there is blood flow within a suspicious lesion.

journal_name

Chest

journal_title

Chest

authors

Silverman JM,Julien PJ,Herfkens RJ,Pelc NJ

doi

10.1378/chest.106.5.1333

subject

Has Abstract

pub_date

1994-11-01 00:00:00

pages

1333-8

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)44318-1

journal_volume

106

pub_type

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