Why rehabilitation research does not work (as well as we think it should)

Abstract:

:Establishing treatment effectiveness is a high priority for rehabilitation research. The use of traditional quantitative null hypotheses to achieve this priority is reviewed. Three problems are identified in the analysis and interpretation of investigations based on statistical testing of hypotheses: (1) confusion of clinical and statistical significance, (2) low statistical power in detecting clinically important results, and (3) a failure to understand the importance of replication in developing a knowledge base for rehabilitation practice. Technical aspects associated with each problem are reviewed and examples presented illustrating the impact of low statistical power and the results of misinterpreting statistical significance tests. Several specific recommendations are made to improve the clinical usefulness of quantitative research conducted in rehabilitation.

journal_name

Arch Phys Med Rehabil

authors

Ottenbacher KJ

doi

10.1016/s0003-9993(95)80021-2

subject

Has Abstract

pub_date

1995-02-01 00:00:00

pages

123-9

issue

2

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(95)80021-2

journal_volume

76

pub_type

杂志文章
  • Effect of heat in increasing the range of knee motion after the development of a joint contracture: an experiment with an animal model.

    abstract:OBJECTIVE:To compare the effects of 2 different heat modalities, infrared and ultrasonic therapy, on a knee flexion contracture. DESIGN:In vivo, experimental, controlled study involving a rat knee joint contracture model that was immobilized using a ligature in flexion for 40 days. SETTING:Collegiate research laborat...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/j.apmr.2005.10.015

    authors: Usuba M,Miyanaga Y,Miyakawa S,Maeshima T,Shirasaki Y

    更新日期:2006-02-01 00:00:00

  • Time course analysis of the effects of botulinum toxin type a on elbow spasticity based on biomechanic and electromyographic parameters.

    abstract:OBJECTIVE:To quantify changes of elbow spasticity over time after botulinum toxin type A (BTX-A) injection in the upper extremity of stroke patients. DESIGN:Before-after trial in which the therapeutic effects were followed up at 2, 6, and 9 weeks after the BTX-A injection (Botox). SETTING:Hospital. PARTICIPANTS:Chro...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/j.apmr.2007.08.166

    authors: Lee HM,Chen JJ,Wu YN,Wang YL,Huang SC,Piotrkiewicz M

    更新日期:2008-04-01 00:00:00

  • Task-dependent weakness at the elbow in patients with hemiparesis.

    abstract:OBJECTIVE:To investigate the task dependence of elbow weakness in patients with hemiparesis. DESIGN:Descriptive study based on interlimb comparisons of maximum voluntary torques (MVTs) generated isometrically in elbow flexion and extension under four task conditions: without explicit control of the torques at adjacent...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/s0003-9993(99)90225-3

    authors: Beer RF,Given JD,Dewald JP

    更新日期:1999-07-01 00:00:00

  • Moderated mediation path analysis of Mexican traumatic brain injury patient social functioning, family functioning, and caregiver mental health.

    abstract:OBJECTIVE:To examine the system of connections among traumatic brain injury (TBI) patient social functioning, family functioning, and caregiver depression and burden in Mexico. DESIGN:Cross-sectional survey. SETTING:A public medical facility. PARTICIPANTS:Mexican TBI patient-caregiver dyads (N=84) participated in th...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/j.apmr.2012.08.210

    authors: Coy AE,Perrin PB,Stevens LF,Hubbard R,Díaz Sosa DM,Espinosa Jove IG,Arango-Lasprilla JC

    更新日期:2013-02-01 00:00:00

  • The effect of the introduction of a case-mix-based funding model of rehabilitation for severe stroke: an Australian experience.

    abstract:OBJECTIVE:To compare resource use of, and outcomes for, rehabilitation for severe stroke before and after the implementation of the Casemix and Rehabilitation Funding Tree case-mix-based funding model. DESIGN:Prospective, observational cohort study. SETTING:Eight inpatient rehabilitation centers in Australia. PARTIC...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.apmr.2007.04.001

    authors: Brock KA,Vale SJ,Cotton SM

    更新日期:2007-07-01 00:00:00

  • Resistance training reduces disability in prostate cancer survivors on androgen deprivation therapy: evidence from a randomized controlled trial.

    abstract:OBJECTIVES:To investigate whether functionally based resistance exercise could improve strength, physical function, and disability among prostate cancer survivors (PCS) on androgen deprivation therapy (ADT); and to explore potential mediators of changes in outcomes from exercise. DESIGN:Randomized controlled trial. S...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.apmr.2014.08.010

    authors: Winters-Stone KM,Dobek JC,Bennett JA,Dieckmann NF,Maddalozzo GF,Ryan CW,Beer TM

    更新日期:2015-01-01 00:00:00

  • Working memory and mental practice outcomes after stroke.

    abstract:OBJECTIVE:To examine the relationship between working memory and motor improvement obtained after a single training session combining mental and physical practice. DESIGN:Before-after trial. SETTING:Laboratory of a university-affiliated research rehabilitation center. PARTICIPANTS:A sample of 12 patients with stroke...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/s0003-9993(03)00771-8

    authors: Malouin F,Belleville S,Richards CL,Desrosiers J,Doyon J

    更新日期:2004-02-01 00:00:00

  • Sex differences in injury severity and outcome measures after traumatic brain injury.

    abstract:OBJECTIVE:To investigate the effect of a patient's sex on various measures of injury severity and outcome after rehabilitation in a matched sample of patients with traumatic brain injury (TBI). DESIGN:Retrospective data were retrieved from a database that contains information routinely collected on all patients admitt...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/j.apmr.2003.05.007

    authors: Slewa-Younan S,Green AM,Baguley IJ,Gurka JA,Marosszeky JE

    更新日期:2004-03-01 00:00:00

  • Renal function in patients with spinal cord injury: the eighth year of a ten-year continuing study.

    abstract::In the eighth year of a continuing study of renal function in patients with spinal cord injury, 78 percent had good function, 13 percent mild deterioration, 4 percent moderate deterioration and 5 percent severe deterioration of kidney function. No single factor was shown to be a dominant cause of decreased function. T...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:

    authors: Price M,Kottke FJ,Olson ME

    更新日期:1975-02-01 00:00:00

  • Static trunk posture in sitting and standing during pregnancy and early postpartum.

    abstract:OBJECTIVE:To investigate the postural alignment of the upper body in the sagittal plane during sitting and standing postures as pregnancy progressed and then in the postpartum period. DESIGN:Longitudinal, repeated-measures design. SETTING:Biomechanics laboratory in an Australian university. PARTICIPANTS:A volunteer ...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1053/apmr.2002.36069

    authors: Gilleard WL,Crosbie J,Smith R

    更新日期:2002-12-01 00:00:00

  • Predicting neurologic recovery in traumatic cervical spinal cord injury.

    abstract:OBJECTIVE:Traumatic spinal cord injury (SCI) affects 8,000 to 10,000 individuals per year in the United States. One of the most difficult tasks confronting the clinician is the discussion of neurologic recovery and prognosis with the patient and/or family. Our objective is to provide a guide for practitioners to accura...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章,评审

    doi:10.1016/s0003-9993(98)90244-1

    authors: Kirshblum SC,O'Connor KC

    更新日期:1998-11-01 00:00:00

  • Disability, chronic illness, and risk selection.

    abstract::As high-cost users of health care, people with disabilities or chronic conditions are particularly vulnerable to risk selection. Preferred risk selection, in which insurers avoid enrolling high-risk people, threatens their access to coverage. Adverse selection, in which high-risk people enroll in the most generous pla...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1053/apmr.2001.20829

    authors: Batavia AI,DeJong G

    更新日期:2001-04-01 00:00:00

  • Histochemical fiber type alterations secondary to exercise training of reinnervating adult rat muscle.

    abstract::The purpose of this study was to evaluate the effect of exercise training on reinnervating rat muscle histochemistry. Adult female Wistar rats in 5 groups (1 control and 4 experimental) underwent bilateral sciatic nerve crush. The 4 experimental groups were exercised on a motorized treadmill at 35% grade and a speed o...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:

    authors: Herbison GJ,Jaweed MM,Ditunno JF

    更新日期:1980-06-01 00:00:00

  • Comparison of a Cognitive-Behavioral Coping Skills Group to a Peer Support Group in a Brain Injury Population.

    abstract:OBJECTIVE:To compare the efficacy of 2 group treatments for persons with brain injury (BI) and their caregivers in promoting perceived self-efficacy (PSE) and emotional and neurobehavioral functioning. DESIGN:Randomized controlled trial. SETTING:Outpatient BI rehabilitation. PARTICIPANTS:Subjects (N=38), including 1...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.apmr.2015.10.097

    authors: Backhaus S,Ibarra S,Parrott D,Malec J

    更新日期:2016-02-01 00:00:00

  • Spinal muscular atrophy: experience in diagnosis and rehabilitation management of 60 patients.

    abstract::Sixty patients with spinal muscular atrophy (SMA) are presented. Although the life span with Type I SMA (Werdnig-Hoffmann disease) may be short, children with the disease can be made more comfortable with appropriate medical care and parental support. Despite electrodiagnostic findings which are not always pathognomon...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:

    authors: Eng GD,Binder H,Koch B

    更新日期:1984-09-01 00:00:00

  • Robot-Guided Neuronavigated Repetitive Transcranial Magnetic Stimulation (rTMS) in Central Neuropathic Pain.

    abstract:OBJECTIVES:To confirm and extend previous results involving repetitive transcranial magnetic stimulation (rTMS) aimed at alleviating refractory central neuropathic pain (CNP). To evaluate pain relief in detail and to assess ongoing benefits after one year of treatment. DESIGN:Prospective observational study. SETTING:...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/j.apmr.2018.04.013

    authors: Quesada C,Pommier B,Fauchon C,Bradley C,Créac'h C,Vassal F,Peyron R

    更新日期:2018-11-01 00:00:00

  • Combining Fast-Walking Training and a Step Activity Monitoring Program to Improve Daily Walking Activity After Stroke: A Preliminary Study.

    abstract:OBJECTIVES:To determine preliminary efficacy and to identify baseline characteristics predicting who would benefit most from fast walking training plus a step activity monitoring program (FAST+SAM) compared with fast walking training (FAST) alone in persons with chronic stroke. DESIGN:Randomized controlled trial with ...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.apmr.2016.01.039

    authors: Danks KA,Pohlig R,Reisman DS

    更新日期:2016-09-01 00:00:00

  • Wrist driven flexor hinge orthosis: linkage design improvements.

    abstract::Wrist driven flexor hinge orthosis (WDFHO) linkage movements were analyzed graphically for existing kit form orthoses and modified orthoses. The graphical analysis indicated improved function by increased torque and resultant pinch force in modified orthoses. A geometric solution to pivot point location which will all...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:

    authors: Stenehjem J,Swenson J,Sprague C

    更新日期:1983-11-01 00:00:00

  • Cervical nonorganic signs: a new clinical tool to assess abnormal illness behavior in neck pain patients: a pilot study.

    abstract:OBJECTIVE:To develop and assess the reliability of a group of cervical nonorganic physical signs to be used as a simple screening tool for identifying patients with low neck pain who exhibit abnormal illness behavior. DESIGN:Survey, consecutive sample. DATA SET:Double masked. SETTING:Functional restoration program. ...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0003-9993(00)90136-9

    authors: Sobel JB,Sollenberger P,Robinson R,Polatin PB,Gatchel RJ

    更新日期:2000-02-01 00:00:00

  • Bladder volume determination: portable 3-D versus stationary 2-D ultrasound device.

    abstract:OBJECTIVE:To investigate how accurately a portable three-dimensional (3-D) scanner and a multipurpose two-dimensional (2-D) real-time scanner determined bladder volumes. STUDY DESIGN:Prospective, controlled clinical trial, single-blind, crossover design. SETTING AND PARTICIPANTS:Twenty-three inpatients with permanent...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0003-9993(00)90215-6

    authors: Schnider P,Birner P,Gendo A,Ratheiser K,Auff E

    更新日期:2000-01-01 00:00:00

  • Assertiveness, anxiety, and interpersonal discomfort among amputees: implications for assertiveness training.

    abstract::It has been suggested that the onset of physical disability may lead to deficits in assertiveness. Therefore, in the present study assertiveness, interpersonal discomfort, anxiety, and demographic variables were investigated among lower limb amputees. Amputees completed self-report measures and hospital visitors serve...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:

    authors: Weinstein CL

    更新日期:1985-10-01 00:00:00

  • Diagnostic imaging of heterotopic ossification with coexistent deep-venous thrombosis in flaccid paraplegia.

    abstract::Heterotopic ossification and deep-venous thrombosis can coexist. This raises potential problems because diagnosis depends heavily on imaging studies, and an ideal imaging study which will cost-effectively and noninvasively diagnose both conditions simultaneously is not readily available. A case of coexistent heterotop...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:

    authors: Haselkorn JK,Britell CW,Cardenas DD

    更新日期:1991-03-01 00:00:00

  • Fatigability in Patients With Multiple Sclerosis During Maximal Concentric Contractions.

    abstract:OBJECTIVE:To compare quadriceps fatigability during maximal concentric contractions in persons with multiple sclerosis (MS) and healthy subjects. DESIGN:Observational study. SETTING:Hospital rehabilitation department. PARTICIPANTS:Persons with MS (n=38) and healthy subjects (n=14) were included (N=52). Torque of the...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/j.apmr.2016.12.014

    authors: Hameau S,Bensmail D,Roche N,Zory R

    更新日期:2017-07-01 00:00:00

  • System-wide Clinical Assessment of Functioning Based on the International Classification of Functioning, Disability and Health in China: Interrater Reliability, Convergent, Known Group, and Predictive Validity of the ICF Generic-6.

    abstract:OBJECTIVE:To validate the International Classification of Functioning, Disability and Health (ICF) Generic-6 in daily routine clinical practice in Mainland China. Specific objectives were to analyze (1) interrater reliability, (2) convergent validity, (3) known group validity, and (4) predictive validity of the ICF Gen...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.apmr.2018.11.014

    authors: Liu S,Reinhardt JD,Zhang X,Ehrmann C,Cai W,Prodinger B,Liu S,Li J

    更新日期:2019-08-01 00:00:00

  • Are tender points associated with cervical radiculopathy?

    abstract:OBJECTIVE:To determine if there is an association between cervical radiculopathy and tender spots in the neck and upper extremity on the side of radiculopathy. DESIGN:Prospective cross-sectional study. SETTING:Outpatient spine clinic within an academic institution. PARTICIPANTS:Convenience sample of 16 subjects with...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/j.apmr.2004.11.023

    authors: Letchuman R,Gay RE,Shelerud RA,VanOstrand LA

    更新日期:2005-07-01 00:00:00

  • Understanding the use of weights in the analysis of data from multistage surveys.

    abstract::Understanding the use of weights in the analysis of data from multistage surveys. Large national surveys are powerful tools with which to examine a variety of important rehabilitation-related issues and are currently the only feasible method to study disability trends over time. Because it is impractical to draw simpl...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/j.apmr.2005.09.021

    authors: Ciol MA,Hoffman JM,Dudgeon BJ,Shumway-Cook A,Yorkston KM,Chan L

    更新日期:2006-02-01 00:00:00

  • Impact of Outpatient Rehabilitation Medicare Reimbursement Caps on Utilization and Cost of Rehabilitation Care After Ischemic Stroke: Do Caps Contain Costs?

    abstract:OBJECTIVE:To estimate the proportion of patients with ischemic stroke who fall within and above the total outpatient rehabilitation caps before and after the Balanced Budget Act of 1997 took effect; and to estimate the cost of poststroke outpatient rehabilitation cost and resource utilization in these patients before a...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/j.apmr.2015.07.008

    authors: Simpson AN,Bonilha HS,Kazley AS,Zoller JS,Simpson KN,Ellis C

    更新日期:2015-11-01 00:00:00

  • Allocation Concealment and Intention-To-Treat Analysis Do Not Influence the Treatment Effects of Physical Therapy Interventions in Low Back Pain Trials: a Meta-epidemiologic Study.

    abstract:OBJECTIVE:To evaluate if allocation concealment and intention-to-treat (ITT) analysis influence the treatment effects of physical therapy interventions in low back pain (LBP) trials. DATA SOURCES:We searched on PubMed, Embase, Cochrane Database of Systematic Reviews, Physiotherapy Evidence Database (PEDro), and CINAHL...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.apmr.2018.12.036

    authors: de Almeida MO,Saragiotto BT,Maher C,Costa LOP

    更新日期:2019-07-01 00:00:00

  • Comparing biofeedback with active exercise and passive treatment for the management of work-related neck and shoulder pain: a randomized controlled trial.

    abstract:OBJECTIVES:To compare the effects of biofeedback with those of active exercise and passive treatment in treating work-related neck and shoulder pain. DESIGN:A randomized controlled trial with 3 intervention groups and a control group. SETTING:Participants were recruited from outpatient physiotherapy clinics and a loc...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.apmr.2010.12.037

    authors: Ma C,Szeto GP,Yan T,Wu S,Lin C,Li L

    更新日期:2011-06-01 00:00:00

  • Health behaviors, body composition, and coronary heart disease risk in women with multiple sclerosis.

    abstract:OBJECTIVES:To explore coronary heart disease risk in a sample of women with multiple sclerosis (MS) by identifying the presence of established risk factors for coronary heart disease and to determine the relationship between disease severity and level of participation in health-related behaviors. DESIGN:Survey study. ...

    journal_title:Archives of physical medicine and rehabilitation

    pub_type: 杂志文章

    doi:10.1016/s0003-9993(03)00466-0

    authors: Slawta JN,Wilcox AR,McCubbin JA,Nalle DJ,Fox SD,Anderson G

    更新日期:2003-12-01 00:00:00