Abstract:
:Diagnosis of visual function losses in glaucomatous patients depends to a large extent on the analysis of the data collected from corresponding psychophysical tests. One of the main difficulties in obtaining reliable data from patients in these tests is the measurement noise caused by the learning effect, inattention, failure of fixation, fatigue etc. Using Kohonen's self-organising feature map, we have developed a computational method to distinguish between the noise and true measurement and to provide an instant assessment of reliability of the computer-based visual function test. In particular we have experimented with 270 test records from glaucoma patients and glaucoma suspects and found that this method provides a satisfactory way of locating and rejecting noise in the test data, an improvement over conventional statistical methods. This method can also provide doctors with a clear view of the patient's behaviour during the test, thus assisting in their diagnostic decision making process.
journal_name
Artif Intell Medjournal_title
Artificial intelligence in medicineauthors
Liu X,Cheng G,Wu JXdoi
10.1016/0933-3657(94)90004-3subject
Has Abstractpub_date
1994-10-01 00:00:00pages
401-16issue
5eissn
0933-3657issn
1873-2860journal_volume
6pub_type
杂志文章abstract::The increasing access to brain signal data using electroencephalography creates new opportunities to study electrophysiological brain activity and perform ambulatory diagnoses of neurological disorders. This work proposes a pairwise distance learning approach for schizophrenia classification relying on the spectral pr...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2020.101852
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Sketching is ubiquitous in medicine. Physicians commonly use sketches as part of their note taking in patient records and to help convey diagnoses and treatments to patients. Medical students frequently use sketches to help them think through clinical problems in individual and group problem solving. Applicat...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2006.07.010
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:Progressive loss of the field of vision is characteristic of a number of eye diseases such as glaucoma which is a leading cause of irreversible blindness in the world. Recently, there has been an explosion in the amount of data being stored on patients who suffer from visual deterioration including field test...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.07.004
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVES:The radiology report is the most important source of clinical imaging information. It documents critical information about the patient's health and the radiologist's interpretation of medical findings. It also communicates information to the referring physicians and records that information for future clinic...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.artmed.2015.09.007
更新日期:2016-01-01 00:00:00
abstract::A nursing database which records patient details and treatments as fields in a standard database format is transformed into a collection, in text form, of patient case days with history. Each case is represented as text strings encoding the patient details, the current problems, treatments and their associated history...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(96)00362-4
更新日期:1997-01-01 00:00:00
abstract::An object-oriented approach has been applied to the different stages involved in developing a knowledge base about insulin metabolism. At an early stage the separation of terminological and assertional knowledge was made. The terminological component was developed by medical experts and represented in CORE. An object-...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/0933-3657(94)90025-6
更新日期:1994-12-01 00:00:00
abstract::We present a stochastic algorithm that computes threshold circuits designed to discriminate between two classes of computed tomography (CT) images. The algorithm employs a partition of training examples into several classes according to the average grey scale value of images. For each class, a sub-circuit is computed,...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(01)00101-4
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:Formulate the induction and control of gene regulatory networks (GRNs) from gene expression data using Partially Observable Markov Decision Processes (POMDPs). METHODS AND MATERIAL:Different approaches exist to model GRNs; they are mostly simulated as mathematical models that represent relationships between ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2017.06.007
更新日期:2017-11-01 00:00:00
abstract::We introduce a novel approach to couple temporal similarity with spatial neighborhood information. This is achieved by concatenating the K nearest, spatially contiguous neighbors of a pixel time-course (TC) of T time-instances. This produces a new TC of (K+1)T time instances. Depending on how "nearest" is defined, we ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(02)00005-2
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVE:The aim of this paper is to provide an improved method for solving the so-called dynamic patient admission scheduling (DPAS) problem. This is a complex scheduling problem that involves assigning a set of patients to hospital beds over a given time horizon in such a way that several quality measures reflecting...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2016.10.002
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:The complex cognitive processes that underlie human performance in 'messy' contexts such as critical care medicine suggest a need for a cognitive model with broad scope to support the understanding of error in such domains. The objective of this research is to characterize the cognition that underlies patient...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2006.03.009
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:Is it possible to predict the severity staging of a Parkinson's disease (PD) patient using scores of non-motor symptoms? This is the kickoff question for a machine learning approach to classify two widely known PD severity indexes using individual tests from a broad set of non-motor PD clinical scales only. ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2013.04.002
更新日期:2013-07-01 00:00:00
abstract::The research at the IIIA has produced over more than a decade two versions of a tool for developing knowledge-based systems: Milord and Milord II. This tool has been mainly used for the development of medical applications. In this paper we summarize the Milord II approximate reasoning approach based on fuzzy sets, and...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(00)00080-4
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:The Arden Syntax is a knowledge-encoding standard, started in 1989, and now in its 10th revision, maintained by the health level seven (HL7) organization. It has constructs borrowed from several language concepts that were available at that time (mainly the HELP hospital information system and the Regenstrie...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2015.11.003
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:There is an ongoing research effort devoted to characterize the signal regularity metrics approximate entropy (ApEn) and sample entropy (SampEn) in order to better interpret their results in the context of biomedical signal analysis. Along with this line, this paper addresses the influence of abnormal spikes ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.06.007
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:We present the implementation and application of a case-based reasoning (CBR) system for breast cancer related diagnoses. By retrieving similar cases in a breast cancer decision support system, oncologists can obtain powerful information or knowledge, complementing their own experiential knowledge, in their m...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2017.02.003
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:Ontologies are widely used in the biomedical domain. While many tools exist for the edition, alignment or evaluation of ontologies, few solutions have been proposed for ontology programming interface, i.e. for accessing and modifying an ontology within a programming language. Existing query languages (such as...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2017.07.002
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND AND MOTIVATION:DNA microarray technology has made it possible to determine the expression levels of thousands of genes in parallel under multiple experimental conditions. Genome-wide analyses using DNA microarrays make a great contribution to the exploration of the dynamic state of genetic networks, and furt...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2005.02.007
更新日期:2005-09-01 00:00:00
abstract::Successful secondary structure predictions provide a starting point for direct tertiary structure modelling, and also can significantly improve sequence analysis and sequence-structure threading for aiding in structure and function determination. Hence the improvement of predictive accuracy of the secondary structure ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.01.009
更新日期:2004-06-01 00:00:00
abstract::Medical diagnosis and therapy planning at modern intensive care units (ICUs) have been refined by the technical improvement of their equipment. However, the bulk of continuous data arising from complex monitoring systems in combination with discontinuously assessed numerical and qualitative data creates a rising infor...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(96)00355-7
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:To use the detection of clinically relevant inconsistencies to support the reasoning capabilities of intelligent agents acting as physicians and tutors in the realm of clinical medicine. METHODS:We are developing a cognitive architecture, OntoAgent, that supports the creation and deployment of intelligent ag...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2012.04.005
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:This paper proposes a novel method for the extraction and classification of individual motor unit action potentials (MUAPs) from intramuscular electromyographic signals. METHODOLOGY:The proposed method automatically detects the number of template MUAP clusters and classifies them into normal, neuropathic or ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2005.09.002
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:After several years of treatment, patients with Parkinson's disease (PD) tend to have, as a side effect of the medication, dyskinesias. Close monitoring may benefit patients by enabling doctors to tailor a personalised medication regimen. Moreover, dyskinesia monitoring can help neurologists make more inform...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2016.01.001
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:Develop and evaluate a natural language processing application for classifying chief complaints into syndromic categories for syndromic surveillance. INTRODUCTION:Much of the input data for artificial intelligence applications in the medical field are free-text patient medical records, including dictated med...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.04.001
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:In this paper, we propose a novel algorithm to extract the active intervals of intracardiac electrograms during atrial fibrillation. METHODS:First, we show that the characteristics of the signal waveform at its inflection points are prominent features that are implicitly used by human annotators for distingu...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2018.02.003
更新日期:2018-04-01 00:00:00
abstract::Disagreement or inconsistencies in mammographic interpretation motivates utilizing computerized pattern recognition algorithms to aid the assessment of radiographic features. We have studied the potential for using artificial neural networks (ANNs) to analyze interpreted radiographic features from film screen mammogra...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(98)00040-2
更新日期:1998-11-01 00:00:00
abstract::Abnormalities in the organization of brain circuits may underlie many types of epilepsy. This hypothesis can best be evaluated in the case of temporal lobe epilepsy, where evidence of rewiring (synaptic reorganization) can be found in the dentate gyrus. Computer modeling of normal and reorganized dentate gyrus was use...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(98)00005-0
更新日期:1998-05-01 00:00:00
abstract::A new algorithm for neural network pruning is presented. Using this algorithm, networks with small number of connections and high accuracy rates for breast cancer diagnosis are obtained. We will then describe how rules can be extracted from a pruned network by considering only a finite number of hidden unit activation...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/0933-3657(95)00019-4
更新日期:1996-02-01 00:00:00
abstract::This work presents a hybrid expert system (HES) intended to minimise some complex problems pervasive to knowledge engineering such as: the knowledge elicitation process, known as the bottleneck of expert systems; the choice of a model for knowledge representation to codify human reasoning; the number of neurons in the...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(00)00090-7
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:Arden Syntax is a standard for representing and sharing medical knowledge in form of independent modules and looks back on a history of 25 years. Its traditional field of application is the monitoring of clinical events such as generating an alert in case of occurrence of a critical laboratory result. Arden S...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2015.09.003
更新日期:2018-11-01 00:00:00