Abstract：
OBJECTIVE:Progressive loss of the field of vision is characteristic of a number of eye diseases such as glaucoma which is a leading cause of irreversible blindness in the world. Recently, there has been an explosion in the amount of data being stored on patients who suffer from visual deterioration including field test data, retinal image data and patient demographic data. However, there has been relatively little work in modelling the spatial and temporal relationships common to such data. In this paper we introduce a novel method for classifying visual field (VF) data that explicitly models these spatial and temporal relationships. METHODOLOGY:We carry out an analysis of our proposed spatio-temporal Bayesian classifier and compare it to a number of classifiers from the machine learning and statistical communities. These are all tested on two datasets of VF and clinical data. We investigate the receiver operating characteristics curves, the resulting network structures and also make use of existing anatomical knowledge of the eye in order to validate the discovered models. RESULTS:Results are very encouraging showing that our classifiers are comparable to existing statistical models whilst also facilitating the understanding of underlying spatial and temporal relationships within VF data. The results reveal the potential of using such models for knowledge discovery within ophthalmic databases, such as networks reflecting the 'nasal step', an early indicator of the onset of glaucoma. CONCLUSION:The results outlined in this paper pave the way for a substantial program of study involving many other spatial and temporal datasets, including retinal image and clinical data.
journal_name
Artif Intell Medjournal_title
Artificial intelligence in medicineauthors
Tucker A,Vinciotti V,Liu X,Garway-Heath Ddoi
10.1016/j.artmed.2004.07.004subject
Has Abstractpub_date
2005-06-01 00:00:00pages
163-77issue
2eissn
0933-3657issn
1873-2860pii
S0933-3657(04)00103-4journal_volume
34pub_type
杂志文章abstract：:A new algorithm for neural network pruning is presented. Using this algorithm, networks with small number of connections and high accuracy rates for breast cancer diagnosis are obtained. We will then describe how rules can be extracted from a pruned network by considering only a finite number of hidden unit activation...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/0933-3657(95)00019-4
更新日期：1996-02-01 00:00:00
abstract：BACKGROUND:The current situation of critical progression in resistance to more effective antibiotics has forced the reuse of old highly toxic antibiotics and, for several reasons, the extension of the indications of combined antibiotic therapy as alternative options to broad spectrum empirical mono-therapy. A key aspec...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2019.101751
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:A metaschema is an abstraction network of the UMLS's semantic network (SN) obtained from a connected partition of its collection of semantic types. A lexical metaschema was previously derived based on a lexical partition which partitioned the SN into semantic-type groups using identical word-usage among the n...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2005.01.002
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVE:In this paper, we propose a novel algorithm to extract the active intervals of intracardiac electrograms during atrial fibrillation. METHODS:First, we show that the characteristics of the signal waveform at its inflection points are prominent features that are implicitly used by human annotators for distingu...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2018.02.003
更新日期：2018-04-01 00:00:00
abstract：:We created an inference engine and query language for expressing temporal patterns in data. The patterns are represented by using temporally-ordered sets of data objects. Patterns are elaborated by reference to new objects inferred from original data, and by interlocking temporal and other relationships among sets of ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/0933-3657(94)90066-3
更新日期：1994-06-01 00:00:00
abstract：BACKGROUND:After several years of treatment, patients with Parkinson's disease (PD) tend to have, as a side effect of the medication, dyskinesias. Close monitoring may benefit patients by enabling doctors to tailor a personalised medication regimen. Moreover, dyskinesia monitoring can help neurologists make more inform...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2016.01.001
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVES:The radiology report is the most important source of clinical imaging information. It documents critical information about the patient's health and the radiologist's interpretation of medical findings. It also communicates information to the referring physicians and records that information for future clinic...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章,多中心研究
doi：10.1016/j.artmed.2015.09.007
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:The problem of designing and managing teams of workers that can collaborate working together towards common goals is a challenging one. Incomplete or ambiguous specification of responsibilities and accountabilities, lack of continuity in teams working in shifts, inefficient organization of teams due to lack o...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2011.08.005
更新日期：2011-11-01 00:00:00
abstract：:Medical diagnosis and therapy planning at modern intensive care units (ICUs) have been refined by the technical improvement of their equipment. However, the bulk of continuous data arising from complex monitoring systems in combination with discontinuously assessed numerical and qualitative data creates a rising infor...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(96)00355-7
更新日期：1996-11-01 00:00:00
abstract：:Case-based approaches predict the behaviour of dynamic systems by analysing a given experimental setting in the context of others. To select similar cases and to control adaptation of cases, they employ general knowledge. If that is neither available nor inductively derivable, the knowledge implicit in cases can be ut...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(98)00057-8
更新日期：1999-03-01 00:00:00
abstract：:Diagnosis of visual function losses in glaucomatous patients depends to a large extent on the analysis of the data collected from corresponding psychophysical tests. One of the main difficulties in obtaining reliable data from patients in these tests is the measurement noise caused by the learning effect, inattention,...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/0933-3657(94)90004-3
更新日期：1994-10-01 00:00:00
abstract：OBJECTIVE:High dose radiation has been well known for increasing the risk of carcinogenesis. However, the understanding of biological effects of low dose radiation is limited. Low dose radiation is reported to affect several signaling pathways including deoxyribonucleic acid repair, survival, cell cycle, cell growth, a...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2010.04.001
更新日期：2010-07-01 00:00:00
abstract：:We present a stochastic algorithm that computes threshold circuits designed to discriminate between two classes of computed tomography (CT) images. The algorithm employs a partition of training examples into several classes according to the average grey scale value of images. For each class, a sub-circuit is computed,...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(01)00101-4
更新日期：2002-02-01 00:00:00
abstract：:As a crucial step of biological event extraction, event trigger identification has attracted much attention in recent years. Deep representation methods, which have the superiorities of less feature engineering and end-to-end training, show better performance than statistical methods. While most deep learning methods ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2019.101783
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:There is an ongoing research effort devoted to characterize the signal regularity metrics approximate entropy (ApEn) and sample entropy (SampEn) in order to better interpret their results in the context of biomedical signal analysis. Along with this line, this paper addresses the influence of abnormal spikes ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2011.06.007
更新日期：2011-10-01 00:00:00
abstract：:This paper describes the INSIDE system, a networked robot system designed to allow the use of mobile robots as active players in the therapy of children with autism spectrum disorders (ASD). While a significant volume of work has explored the impact of robots in ASD therapy, most such work comprises remotely operated ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2018.12.003
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVE:Coronary artery disease has been described as one of the curses of the western world, as it is one of its most important causes of mortality. Therefore, clinicians seek to improve diagnostic procedures, especially those that allow them to reach reliable early diagnoses. In the clinical setting, coronary arter...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2011.04.009
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:We present the implementation and application of a case-based reasoning (CBR) system for breast cancer related diagnoses. By retrieving similar cases in a breast cancer decision support system, oncologists can obtain powerful information or knowledge, complementing their own experiential knowledge, in their m...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2017.02.003
更新日期：2017-03-01 00:00:00
abstract：:Artificial intelligence (AI) will pave the way to a new era in medicine. However, currently available AI systems do not interact with a patient, e.g., for anamnesis, and thus are only used by the physicians for predictions in diagnosis or prognosis. However, these systems are widely used, e.g., in diabetes or cancer p...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2019.101706
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVES:Access to the world wide web and multimedia content is an important aspect of life. We present a web browser and a multimedia user interface adapted for control with a brain-computer interface (BCI) which can be used by severely motor impaired persons. METHODS:The web browser dynamically determines the most...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2014.12.001
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:This work proposes creating an automatic system to locate and segment the optic nerve head (ONH) in eye fundus photographic images using genetic algorithms. METHODS AND MATERIAL:Domain knowledge is used to create a set of heuristics that guide the various steps involved in the process. Initially, using an ey...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2008.04.005
更新日期：2008-07-01 00:00:00
abstract：:Standard Back Propagation (BP), Partially Recurrent (PR) and Cascade-Correlation (CC) neural networks were used to predict the side of finger movement on the basis of non-averaged single trial multi-channel EEG data recorded prior to movement. From these EEG data, power values were calculated and used as parameters fo...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/0933-3657(93)90040-a
更新日期：1993-12-01 00:00:00
abstract：:As part of a plan to promote semi-automatic knowledge acquisition for the medical consultant system CADIAG-II/RHEUMA, this study sought to explore and cope with the variability of results that may be anticipated when performing knowledge acquisition with patient data from different patient settings. Patient data were ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(02)00025-8
更新日期：2002-07-01 00:00:00
abstract：:A nursing database which records patient details and treatments as fields in a standard database format is transformed into a collection, in text form, of patient case days with history. Each case is represented as text strings encoding the patient details, the current problems, treatments and their associated history...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(96)00362-4
更新日期：1997-01-01 00:00:00
abstract：:In this paper, we describe a system for automating the diagnosis of myocardial perfusion from single-photon emission computerized tomography (SPECT) images of male and female hearts. Initially we had several thousand of SPECT images, other clinical data and physician-interpreter's descriptions of the images. The image...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(02)00055-6
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVE:Traditional Chinese medicine (TCM) is a scientific discipline, which develops the related theories from the long-term clinical practices. The large-scale clinical data are the core empirical knowledge source for TCM research. This paper introduces a clinical data warehouse (CDW) system, which incorporates the...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2009.07.012
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVE:The aim of this paper is to provide an improved method for solving the so-called dynamic patient admission scheduling (DPAS) problem. This is a complex scheduling problem that involves assigning a set of patients to hospital beds over a given time horizon in such a way that several quality measures reflecting...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2016.10.002
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:While EIRA has proved to be successful in the detection of anomalous patient responses to treatments in the Intensive Care Unit, it could not describe to clinicians the rationales behind the anomalous detections. The aim of this paper is to address this problem. METHODS:Few attempts have been made in the pas...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/j.artmed.2013.02.003
更新日期：2013-05-01 00:00:00
abstract：:This paper presents a computer-based model for differential diagnosis of specific language impairment (SLI), a language disorder that, in many cases, cannot be easily diagnosed. This difficulty necessitates the development of a methodology to assist the speech therapist in the diagnostic process. The methodology tool ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/s0933-3657(02)00076-3
更新日期：2003-11-01 00:00:00
abstract：:INTERNIST-I was an expert system designed in the early 1970's to diagnose multiple diseases in internal medicine by modelling the behaviour of clinicians. Its form and operation are described, and evaluations of the system are surveyed. The major result of the project was its knowledge base which has been used in succ...
journal_title：Artificial intelligence in medicine
pub_type： 杂志文章
doi：10.1016/0933-3657(94)00028-q
更新日期：1995-04-01 00:00:00
