Abstract:
:Analysis of sperm has been investigated as a possible method to examine the toxicity of environmental contaminants. The amphibian sperm inhibition toxicological test (ASITT) method examines the effects of contaminants on Xenopus laevis (African clawed frog) sperm motility and path trajectories. As part of a preliminary validation of the method, the effects of increasing divalent metal ion, zinc (Zn2+), on X. laevis sperm motility were examined. We hypothesized that Zn2+ concentration would have significant inhibitory effects on percent sperm motility, velocities, and trajectories. The Zn2+ was added to a control solution in concentrations from 0 to 1,417 microg/L. Sperm cells were videotaped at 30 frames per second under x 400 microscope, and percent motility was recorded and paths were mapped by marking the change in position of the sperm head over a period of 1 s. Sperm motility was categorized as progressive, hyperactivated, idle, or nonmotile, and velocities and trajectories were calculated on the basis of x,y coordinates. Increasing Zn2+ concentrations caused a significant exponential decay in percent total motility and progressive motility. Straight-line velocity increased with increasing Zn2+ concentrations. Overall, results suggest that Zn2+ may be interfering with cellular processes, such as cellular respiration, flagellar bending, or ion exchange, thereby inhibiting sperm motility.
journal_name
Environ Toxicol Chemjournal_title
Environmental toxicology and chemistryauthors
Christensen JR,Bishop CA,Richardson JS,Pauli B,Elliott Jdoi
10.1897/03-573.1subject
Has Abstractpub_date
2004-12-01 00:00:00pages
2950-5issue
12eissn
0730-7268issn
1552-8618journal_volume
23pub_type
杂志文章abstract::Glyphosate-based herbicides are the most commonly used worldwide because they are effective and relatively nontoxic to nontarget species. Unlimited and uncontrolled use of such pesticides can have serious consequences for human health and ecological balance. The present study evaluated the acute toxicity and genotoxic...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3580
更新日期:2017-07-01 00:00:00
abstract::Hydrocarbon-inducible cytochrome P4501A (CYP1A) expression was measured, as ethoxyresorufin-O-deethylase (EROD) activity, in livers of wintering harlequin ducks (Histrionicus histrionicus) captured in areas of Prince William Sound, Alaska, USA, oiled by the 1989 Exxon Valdez spill and in birds from nearby unoiled area...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.129
更新日期:2010-05-01 00:00:00
abstract::The influence of seasonal changes in water conditions and parameters on several major pharmacologically active compounds (PhACs) and s-triazine herbicides was assessed in the wastewater and sewage treatment plant (WSTP) effluent as well as the downstream surface water from sites on the Canadian side of the upper Detro...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-571r.1
更新日期:2006-09-01 00:00:00
abstract::Widespread use of pesticides often contaminates natural habitats, exposing nontarget organisms to pesticides that were designed to control pest populations. Even low levels of pesticides can affect aquatic communities both directly and indirectly. Previous work has shown that trace amounts of the pesticide chlorpyrifo...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4240
更新日期:2018-10-01 00:00:00
abstract::Polycyclic aromatic hydrocarbon (PAHs) were measured in sediments from 29 sites throughout Taihu Lake in China during 2 seasons to investigate spatiotemporal characteristics and source contributions using a 3-way source apportionment approach to positive matrix factorization (PMF3). Seasonal and spatial variations of ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2628
更新日期:2014-08-01 00:00:00
abstract::Laboratory bioassays were conducted to evaluate the effects on honeybee behavior of sublethal doses of insecticides chronically administered orally or by contact. Emergent honeybees received a daily dose of insecticide ranging from one-fifth to one-five-hundredth of the median lethal dose (LD50) during 11 d. After exp...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/08-110.1
更新日期:2009-01-01 00:00:00
abstract::The octanol-water partioning of inorganic mercury decreased with increasing sulfide, supporting a model that predicts decreased fractions of neutral Hg-S species with increasing sulfide. These results help explain the decreased availability of Hg to methylating bacteria under sulfidic conditions, and the inverse relat...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.5620181004
更新日期:1999-10-01 00:00:00
abstract::Physiologically based toxicokinetic (PBTK) modeling enables researchers to predict internal tissue concentrations for various species exposed to exogenous compounds through different routes at varying concentrations without having to run in vivo experiments for each scenario. Parameters for the models may be gathered ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4390
更新日期:2019-05-01 00:00:00
abstract::Bromoxynil (3,5-dibromo-4-hydroxybenzonitrile) is a halogenated aromatic nitrile herbicide used on a variety of crops for the postemergence control of annual broad-leaved weeds. The anaerobic biodegradability of bromoxynil and its aerobic transformation product, 3,5-dibromo-4-hydroxybenzoate, were examined in enrichme...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::Temperature is an important factor affecting toxicity, determining chemical toxicokinetics and toxicodynamics in poikilothermic organisms. Because metabolic rates are also affected by temperature, interactions between the emergence of toxic effects and time are very likely. The aim of the present study was to investig...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2563
更新日期:2014-06-01 00:00:00
abstract::Luminescent bacterium Shk1 was created for the purpose of testing and screening the toxicity of activated sludge wastewater treatment plant influent to avoid toxic shock to the wastewater treatment plant microorganisms. The toxicity of a number of organic compounds was tested using an assay employing Shk1. Because the...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract::The toxicity of nitroaromatic (2,4-diaminonitrotoluene [2,4-DANT] and 1,3,5-trinitrobenzene [TNB]) and 14C-labeled cyclonitramine compounds (hexahydro-1,3,5-trinitro-1,3,5-triazine [RDX] and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine [HMX]) to the marine polychaete Neanthes arenaceodentata and the estuarine amph...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract::The toxicity and estrogenicity of a final treated municipal effluent was examined while flowing through a constructed wetland in north-central Texas, USA. Fish data were collected, and a baseline wetland characterization was performed to assess wetland treatment potential for these effluent properties. Vitellogenin (V...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/1551-5028(2001)020<2268:aoteat>2.0.co;2
更新日期:2001-10-01 00:00:00
abstract::The toxicity and uptake of polycyclic aromatic hydrocarbons (PAHs) by earthworms were measured in soil samples collected from manufactured-gas plant sites having a wide range in PAH concentrations (170-42,000 mg/kg) and soil characteristics. Samples varied from vegetated soils to pure lampblack soot and had total orga...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/06-608R.1
更新日期:2007-09-01 00:00:00
abstract::Pharmaceuticals and personal care products (PPCPs) such as caffeine and sulfamethoxazole have been detected in the estuarine environment. The present study characterized effects of a maternal exposure of these compounds on the development of the daggerblade grass shrimp Palaemonetes pugio from embryo to juvenile life ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2669
更新日期:2014-09-01 00:00:00
abstract::A market for bisphenol A (BPA) replacement compounds has emerged due to restrictions on the use of BPA. Some of these compounds were detected in the environment, yet little is known about their toxicological properties. In the present study, an avian in vitro toxicogenomic approach was used to compare the effects of f...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4985
更新日期:2021-01-19 00:00:00
abstract::There is growing concern about possible effects of exploitation of the Alberta Oil Sands on the ambient environment, including possible effects on populations of fishes in the Athabasca River and farther downstream in Lake Athabasca and the Slave River. In the present study, concentrations of metals in dorsal muscle t...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4852
更新日期:2020-11-01 00:00:00
abstract::A systematic comparison of Cu toxicity thresholds was made between freshly spiked soils and soils in which elevated Cu concentrations have been present for various times. Three uncontaminated soils were spiked and experimentally leached or incubated outdoors for up to 18 months. Additionally, five field-contaminated s...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-673r.1
更新日期:2006-03-01 00:00:00
abstract::As the main optical isomer of metalaxyl, metalaxyl-M has been widely used worldwide in recent years because of its notable effect on the prevention and control of crop diseases. Together with the toxicity and degradation of metalaxyl-M, the chemical has attracted the attention of researchers. The present study examine...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2682
更新日期:2014-10-01 00:00:00
abstract::Triclosan (TCS) is a common constituent of personal care products and is frequently present in biosolids. Application of biosolids to land transfers significant amounts of TCS to soils. Because TCS is an antimicrobial and is toxic to some aquatic organisms, concern has arisen that TCS may adversely affect soil organis...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.1721
更新日期:2012-03-01 00:00:00
abstract::Treatment of municipal wastewater reduces the concentrations of some pharmaceuticals and personal care products (PPCPs), hormones, and drugs of abuse. However, reduced concentrations of these micropollutants in wastewater may not correlate with reduced toxicity because transformations of micropollutants and/or the for...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3939
更新日期:2018-01-01 00:00:00
abstract::The fish acute toxicity test method is foundational to aquatic toxicity testing strategies, yet the literature lacks a concise sample size assessment. Although various sources address sample size, historical precedent seems to play a larger role than objective measures. We present a novel and comprehensive quantificat...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4098
更新日期:2018-06-01 00:00:00
abstract::An original species-selection method for the building of test batteries is presented. This method is based on the statistical analysis of the biological and ecological trait patterns of species. It has been applied to build a macroinvertebrate test battery for the assessment of sediment toxicity, which efficiently des...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-559r.1
更新日期:2005-09-01 00:00:00
abstract::Three environmental multimedia models of varying degrees of complexity are compared to assess when simple models are adequate and when more complex models are advantageous. The simplest model, the level II (L-II) model, assumes all environmental media are at chemical equilibrium, whereas the more complex models treat ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2003-06-01 00:00:00
abstract::The authors derive predicted-no-effect concentrations (PNECs) for the steroid estrogens (estrone [E1], 17β-estradiol [E2], estriol [E3], and 17α-ethinylestradiol [EE2]) appropriate for use in risk assessment of aquatic organisms. In a previous study, they developed a PNEC of 0.35 ng/L for EE2 from a species sensitivit...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.1825
更新日期:2012-06-01 00:00:00
abstract::We analyzed the fate of organotins in seawater and sediments from Tokyo Bay, Japan, by gas chromatography/inductively coupled plasma mass spectrometry. We also measured the toxicity of methylated butyltins by in vitro bioassays, the retinoid X receptor (RXR) activation method, and the marine luminescent bacterium Vibr...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/06-599.1
更新日期:2007-12-01 00:00:00
abstract::More or less well-defined mixtures of antibiotics used in aquacultures may be distributed in the aquatic environment. Therefore, a systematic mixture ecotoxicity study was performed with the aquaculture antibiotics oxytetracycline, oxolinic acid, erythromycin, florfenicol, and flumequine. Test organisms were freshwate...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-415r.1
更新日期:2006-08-01 00:00:00
abstract::recent industrial developments have resulted in an increase in use of so-called technology-critical elements (TCEs), for which the potential impacts on aquatic biota remain to be evaluated. In the present study, quantitative ion character activity relationships (QICARs) have been developed to relate intrinsic metal pr...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.4960
更新日期:2020-12-14 00:00:00
abstract::The Athabasca River basin, located in Alberta, Canada, covers 157, 000 km(2) and holds significant cultural and economic importance. Recent research assessed changes in several water quality and quantity parameters that have changed both spatially (along the river continuum) and temporally (pre-development and present...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2081
更新日期:2013-03-01 00:00:00
abstract::A battery of biomarkers is often used to evaluate the effects of exposure to chemical contaminants and detect responses to environmental stress. Unfortunately, field application of biomarkers is subject to various constraints (e.g., the availability of living material) that can limit data acquisition and prevent the u...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00