[Increase of interleukin-2 soluble receptors in multiple sclerosis: preliminary study in 26 patients].

Abstract:

:Serum samples were analysed for interleukin-2 receptors levels (sIL-2R) in 26 patients with definite multiple sclerosis as defined by Poser and col. Three groups of patients form the basis of this study: group I, with 14 patients with clinical evidence of active disease; group II, with 12 patients with clinically stable multiple sclerosis; and group III, with 8 patients with other neurological diseases. Blood was collected by venipuncture and centrifuged. All samples were stored at -20 degrees C until testing. The assay used monoclonal antibodies against epitopes of interleukin-2 receptors. In the wells of a microtiter plate coated with anti-soluble interleukin-2 receptors (Immunotech SA) samples to be measured or standards are incubated in the presence of a second monoclonal antibody conjugated with alkaline phosphatase. The amount of bound enzyme-conjugate is measured by adding a chromogenic substrate. The intensity of the resulting colour is proportional to the sIL-2R concentration present in the sample. Increased serum levels of sIL-2R were found in 7 of 14 patients with active multiple sclerosis (50%), in only 1 of the 12 patients with clinically stable multiple sclerosis and in none of the patients with other neurological diseases.

journal_name

Arq Neuropsiquiatr

authors

Tilbery CP,Felipe E,Mota IM,Scheinberg MA

doi

10.1590/s0004-282x1994000200011

subject

Has Abstract

pub_date

1994-06-01 00:00:00

pages

216-20

issue

2

eissn

0004-282X

issn

1678-4227

journal_volume

52

pub_type

杂志文章
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    doi:10.1590/s0004-282x1977000100002

    authors: Pereira W,Godoy R,Ferreira C

    更新日期:1977-03-01 00:00:00

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    authors: Lima FT,Brunoni D,Schwartzman JS,Pozzi MC,Kok F,Juliano Y,Pereira Lda V

    更新日期:2009-09-01 00:00:00

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    doi:10.1590/s0004-282x2007000600023

    authors: Lin J,Lin K,Masruha MR,Vilanova LC

    更新日期:2007-12-01 00:00:00

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    journal_title:Arquivos de neuro-psiquiatria

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    doi:10.1590/s0004-282x1999000100016

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    更新日期:1999-03-01 00:00:00

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    journal_title:Arquivos de neuro-psiquiatria

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    doi:10.1590/s0004-282x2009000200017

    authors: Faleiros AT,Resende LA,Zanini MA,Castro HA,Gabarra RC

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    journal_title:Arquivos de neuro-psiquiatria

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    更新日期:2002-03-01 00:00:00

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    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

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  • Celebrating the 70 years of pyridostigmine on therapy of Myasthenia Gravis: historical aspects of the preliminary trials.

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    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,评审

    doi:10.1590/0004-282X20190189

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    journal_title:Arquivos de neuro-psiquiatria

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    journal_title:Arquivos de neuro-psiquiatria

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    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1997000200008

    authors: Nunes ML,Da Costa JC,Taufer L

    更新日期:1997-06-01 00:00:00

  • Cerebellar glioblastoma multiforme in an adult.

    abstract::Cerebellar glioblastoma multiforme (GBM) is a rare tumor. This is the third case published in Brazilian literature and, the last one has been described more than 15 years ago. The aggressive behavior of GBM prompts for fast treatment, which can be hampered by the fact that the diagnosis of GBM requires a high degree o...

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    pub_type: 杂志文章,评审

    doi:10.1590/s0004-282x2006000100028

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    更新日期:2006-03-01 00:00:00

  • [Traumatic brain injury in children and adolescents at Salvador City, Bahia, Brazil].

    abstract:OBJECTIVE:To verify the frequency of traumatic brain injury (TBI) in the people between 0 and 19 years of age, in accordance to gender, age and cause of trauma. METHOD:Descriptive study made through a period of a year, in all TBI victims, aged until 19 years admitted in a reference trauma center. RESULTS:The sample h...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2006000600020

    authors: Melo JR,de Santana DL,Pereira JL,Ribeiro TF

    更新日期:2006-12-01 00:00:00

  • [Event-related cerebral potentials. Classification and clinical use].

    abstract::Event-related potentials (ERP) constitute an heterogeneous group of brain electrical signals time-locked to sensory stimulation, motor responses, and associative processes, recorded using computer averaging. Several kinds of brain electric activity are encompassed by the generic term "event related potentials": sensor...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1979000300006

    authors: Lolas F

    更新日期:1979-09-01 00:00:00

  • Lumbar puncture in patients using anticoagulants and antiplatelet agents.

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    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,评审

    doi:10.1590/0004-282X20160098

    authors: Domingues R,Bruniera G,Brunale F,Mangueira C,Senne C

    更新日期:2016-08-01 00:00:00

  • Traditional biomarkers in narcolepsy: experience of a Brazilian sleep centre.

    abstract:UNLABELLED:This study was thought to characterized clinical and laboratory findings of a narcoleptic patients in an out patients unit at São Paulo, Brazil. METHOD:28 patients underwent polysomnographic recordings (PSG) and Multiple Sleep Latency Test (MSLT) were analyzed according to standard criteria. The analysis of...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2010000500007

    authors: Coelho FM,Pradella-Hallinan M,Pedrazzoli M,Soares CA,Fernandes GB,Gonçalves AL,Tufik S,Bittencourt LR

    更新日期:2010-10-01 00:00:00

  • [Validation of a questionnaire for the diagnosis of headache in an outpatient clinic at a university hospital].

    abstract::Headache is a common complaint with a high prevalence in ambulatory settings. The physical and neurological examinations are frequently normal. The use of questionnaires as a screening methods for patients with primary headache could facilitate the diagnosis in non-specialized medical centers. In the present study, we...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1997000300003

    authors: Benseñor IJ,Lotufo PA,Pereira AC,Tannuri AC,Issa FK,Akashi D,Fucciolo DQ,Kakuda ES,Kanashiro H,Lobato ML,Titan SO,Galvão TF,Martins Mde A

    更新日期:1997-09-01 00:00:00

  • [Reversible cerebral changes in hemolytic-uremic syndrome].

    abstract::The hemolytic-uremic syndrome is a pathology characterized by a triad consisting of acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia, with complications of the central nervous system arising in a considerable number of cases. Altered cranial computerized tomography examinations usually revea...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1995000200019

    authors: Santos AC,Siqueira Neto JI,Fabio SR

    更新日期:1995-06-01 00:00:00

  • [Tumoral form of cerebral cysticercosis: diagnosis by computerized tomography].

    abstract::Solitary granulomatous lesions due to cysticercosis in the brain were found by computed tomography in six patients. The CT images were in all cases very similar to those from brain neoplasms. The cerebrospinal fluid complement fixation test for cysticercosis was negative in all of the cases. The definite etiological d...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1980000400010

    authors: Shibata MK,Bianco E,Moreira FA,de Almeida GM

    更新日期:1980-12-01 00:00:00

  • Dabigatran and warfarin in nonvalvular atrial fibrillation or atrial flutter in outpatient clinic practice in Brazil.

    abstract:OBJECTIVES:To compare warfarin and dabigatran for thromboembolic event prevention in patients with nonvalvular atrial fibrillation or atrial flutter. METHODS:This was a retrospective cohort of participants with nonvalvular atrial fibrillation or atrial flutter using either warfarin or dabigatran in a reference center ...

    journal_title:Arquivos de neuro-psiquiatria

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    doi:10.1590/0004-282X20190005

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  • Decompressive craniectomy versus conservative treatment: limits and possibilities in malignant stroke.

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    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

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    authors: Maia IHM,Melo TP,Lima FO,Carvalho JJF,Mont'alverne FJA,Lopes JÚnior E,DiÓgenes MB,Cunha TSL,Queiroz BMA,Tamietti MF,Maia FM

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  • [Ectopic meningioma of the calvarium: report of a case].

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    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1982000200009

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    更新日期:1982-06-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2020-10-01 00:00:00

  • Quality of life issues and occupational performance of persons with epilepsy.

    abstract::Epilepsy causes restrictions in the performance of various daily activities. The aiming of this study was to investigate whether these restrictions affect the perceived quality of life. The assessments Quality of Life in Epilepsy-31 (QOLIE-31) and Canadian Occupational Performance Measure (COPM) were applied in a samp...

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    pub_type: 杂志文章

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    authors: Nickel R,Silvado CE,Germiniani FM,Paola Ld,Silveira NL,Souza JR,Robert C,Lima AP,Pinto LM

    更新日期:2012-02-01 00:00:00

  • Traumatic subdural hygroma: five cases with changed density and spontaneous resolution.

    abstract::Thirty-four consecutive adult patients with subdural traumatic hygroma were analysed for clinical evolution, serial computed tomography scan (CT), and magnetic resonance imaging (MRI) over a period of several months. Five of the patients presented CT scan and MRI evolution data showing increasing density over a period...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2007000100015

    authors: Zanini MA,Resende LA,Freitas CC,Yamashita S

    更新日期:2007-03-01 00:00:00

  • Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system.

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    pub_type: 杂志文章

    doi:10.1590/s0004-282x2007000300013

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    更新日期:2003-06-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1590/s0004-282x1980000400002

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    更新日期:1980-12-01 00:00:00

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    更新日期:2017-04-01 00:00:00