Lumbar puncture in patients using anticoagulants and antiplatelet agents.

Abstract:

:The use of anticoagulants and antiplatelet agents has largely increased. Diagnostic lumbar puncture in patients taking these drugs represents a challenge considering the opposing risks of bleeding and thrombotic complications. To date there are no controlled trials, specific guidelines, nor clear recommendations in this area. In the present review we make some recommendations about lumbar puncture in patients using these drugs. Our recommendations take into consideration the pharmacology of these drugs, the thrombotic risk according to the underlying disease, and the urgency in cerebrospinal fluid analysis. Evaluating such information and a rigorous monitoring of neurological symptoms after lumbar puncture are crucial to minimize the risk of hemorrhage associated neurological deficits. An individualized patient decision-making and an effective communication between the assistant physician and the responsible for conducting the lumbar puncture are essential to minimize potential risks.

journal_name

Arq Neuropsiquiatr

authors

Domingues R,Bruniera G,Brunale F,Mangueira C,Senne C

doi

10.1590/0004-282X20160098

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

679-86

issue

8

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2016000800679

journal_volume

74

pub_type

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