Abstract:
:The use of anticoagulants and antiplatelet agents has largely increased. Diagnostic lumbar puncture in patients taking these drugs represents a challenge considering the opposing risks of bleeding and thrombotic complications. To date there are no controlled trials, specific guidelines, nor clear recommendations in this area. In the present review we make some recommendations about lumbar puncture in patients using these drugs. Our recommendations take into consideration the pharmacology of these drugs, the thrombotic risk according to the underlying disease, and the urgency in cerebrospinal fluid analysis. Evaluating such information and a rigorous monitoring of neurological symptoms after lumbar puncture are crucial to minimize the risk of hemorrhage associated neurological deficits. An individualized patient decision-making and an effective communication between the assistant physician and the responsible for conducting the lumbar puncture are essential to minimize potential risks.
journal_name
Arq Neuropsiquiatrjournal_title
Arquivos de neuro-psiquiatriaauthors
Domingues R,Bruniera G,Brunale F,Mangueira C,Senne Cdoi
10.1590/0004-282X20160098subject
Has Abstractpub_date
2016-08-01 00:00:00pages
679-86issue
8eissn
0004-282Xissn
1678-4227pii
S0004-282X2016000800679journal_volume
74pub_type
杂志文章,评审abstract::Gerstmann-Sträussler-Scheinker is a genetic prion disease and the most common mutation is p.Pro102Leu. We report clinical, molecular and neuropathological data of seven individuals, belonging to two unrelated Brazilian kindreds, carrying the p.Pro102Leu. Marked differences among patients were observed regarding age at...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/0004-282X20170049
更新日期:2017-06-01 00:00:00
abstract:UNLABELLED:Antiepileptic drugs (AED) may cause body weight changes. OBJECTIVE:To evaluate the dietary habits and body weight associated with AED in epileptic patients. METHOD:Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval b...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2010000200024
更新日期:2010-04-01 00:00:00
abstract::Percutaneous vertebroplasty (PV) is a minimally invasive procedure used to treat focal pain from compressive vertebral fracture. The PV is indicated for the treatment of debilitating vertebral pain from osteoporotic vertebral fractures, metastatic disease (osteolytic), myeloma and hemagioma. We analyzed the results of...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2003000400019
更新日期:2003-09-01 00:00:00
abstract::Clear and dark satellite cell classes were identified by electron microscopy in the lumbar sensory ganglia of domestic fowl in 8 pre and 4 post-hatching stages of development. Some cytologic differences found between the two classes relating to the rough-endoplasmic reticulum, ribosomes, Golgi apparatus and junctional...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1988000100002
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abstract:UNLABELLED:Fibromatosis is a locally aggressive, proliferative fibroblastic lesion affecting musculoaponeurotic structures, most often in the limbs and trunk. Intracranial fibromatosis is extremely rare and requires aggressive treatment to prevent recurrence. CASE DESCRIPTION:We present the case of a 20 year old woman...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2006000300031
更新日期:2006-06-01 00:00:00
abstract::Two syndromatic forms of Creutzfeldt-Jakob disease are illustrated with data from two cases confirmed by necropsy and studied by means of electroencephalogram, evoked potential recording and neuropathological techniques. One of the cases presented the typical hypersynchronous periodic discharges through to be characte...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1982000100005
更新日期:1982-03-01 00:00:00
abstract::Neuroradiologic, neuropathologic and immunohistochemical features are reported in a young man with a impairment of the central nervous system mimicking an acute diffuse encephalomyelitis. A white male, 17 years old, healthy till 4 months before, when developed a right hemiparesis and after 2 months a bilateral hemipar...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1997000300023
更新日期:1997-09-01 00:00:00
abstract::Tourette syndrome (TS) is a neuropsychiatric disorder characterized by a combination of multiple motor tics and at least one phonic tic. TS patients often have associated behavioral abnormalities such as obsessive compulsive disorder, attention deficit and hyperactive disorder. Coprolalia, defined as emission of obsce...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2001000400019
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abstract::Significant advances in the understanding and management of Duchenne muscular dystrophy (DMD) took place since international guidelines were published in 2010. Our objective was to provide an evidence-based national consensus statement for multidisciplinary care of DMD in Brazil. A combination of the Delphi technique ...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章,实务指引
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更新日期:2017-08-01 00:00:00
abstract:UNLABELLED:The hereditary ataxias comprise a very large spectrum of genetically determined neurodegenerative disorders with progressive ataxia as the prominent symptom. In order to measure the severity of cerebellar ataxia in an easier and more practical way, it was proposed a new scale: the Scale for the Assessment an...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
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abstract::The authors report 6 cases of cerebrospinal fluid (CSF) examinations in which malignant cells were found. In 5 cases the finding was incidental: medulloblastoma (case 1); malignant melanoma (case 2); adenocarcinoma (case 3); meningitis carcinomatosa (case 4) and neuroleukaemia (case 5). In only one case neuroleukaemia...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1986000200008
更新日期:1986-06-01 00:00:00
abstract::To keep up to date with new advances in medical care and in the understanding of the disease process which affects their specific patients neurologists need to develop strategies for continuing education. They must be learners throughout their careers and the learning must be self-directed, active and independent. The...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1992000200023
更新日期:1992-06-01 00:00:00
abstract::The authors present a retrospective study of 50 patients with hepatic encephalopathy treated at the University Hospital, Faculty of Medicine of Ribeirão Preto since 1959 and discuss clinical, laboratory and anatomo-pathologic aspects. The diagnoses of the different types of liver disease as well as the factors that tr...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1984000400002
更新日期:1984-12-01 00:00:00
abstract::The risk/benefit ratio of acute anticoagulation in ischaemic cerebro-vascular disease is not clearly established. A simple and safe intermittent intravenous heparin regimen (20000 IU daily) was used prospectively in 50 patients of 57 +/- 14 (m +/- sd) years of age whose blood pressures ranged from normal to severe hyp...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1986000100003
更新日期:1986-03-01 00:00:00
abstract::The extra-intracranial bypass may be used in selected cases of brain vascular insufficiency refractory to clinical treatment. We report a case of encephalic ischemia in the territory of the right middle cerebral artery due to occlusion of the ipsilateral internal carotid artery, with consequent reduction of the perfus...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2004000200025
更新日期:2004-06-01 00:00:00
abstract::Two cases of myotonic dystrophy with excessive daytime somnolence are described. All-night polysomnographic studies were performed revealing high number of central sleep apnea which triggered micro-arousals and awakenings leading to decrease of sleep efficiency as well as of stage 3, 4 and REM. Obstructive and mixed a...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1985000400009
更新日期:1985-12-01 00:00:00
abstract::Primary progressive multiple sclerosis (PPMS) is defined clinically with a progressive course from onset. There is no approved treatment for the PPMS. Methylprednisolone IV (MP) hastens the recovery from MS relapses. We studied 11 patients that met the MacDonald's diagnostic criteria for PPMS. The dose of MP was 30 mg...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2008000300013
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statins, have been associated with improved clinical outcomes after ischemic stroke and subarachnoid hemorrhage, but with an increased risk of incidental spontaneous intracerebral hemorrhage (ICH). We investigated whether the statin use ...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2011000400008
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abstract:OBJECTIVE:To determine frequency, etiology, site and clinical and laboratory findings of ventriculoperitoneal shunt (VPS) infections in children and adolescents with hydrocephalus managed in Hospital Governador João Alves Filho, Aracaju SE, Brazil. METHOD:A non-controlled prospective observational study comprising 50 ...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2007000100024
更新日期:2007-03-01 00:00:00
abstract::There are few descriptions about middle-aged patients who have nonconvulsive status epilepticus, absence status. We reported the clinical case of a woman, 52-year-old, diabetic, referred to the emergency room in a confusional state. Initial electroencephalogram showed continuous typical, bilateral, symmetric and synch...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1997000400022
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abstract:OBJECTIVE:The aim of this study is to determine if the University of Pennsylvania's Smell Identification Test (UPSIT) is an accurate diagnostic tool for olfactory dysfunction in Parkinson's disease (PD). METHOD:We included 138 non-demented PD subjects and 175 control subjects matched by gender. Smell identification wa...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/0004-282X20130190
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To verify the frequency of traumatic brain injury (TBI) in the people between 0 and 19 years of age, in accordance to gender, age and cause of trauma. METHOD:Descriptive study made through a period of a year, in all TBI victims, aged until 19 years admitted in a reference trauma center. RESULTS:The sample h...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2006000600020
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To verify the auditory selective attention in children with stroke. METHODS:Dichotic tests of binaural separation (non-verbal and consonant-vowel) and binaural integration - digits and Staggered Spondaic Words Test (SSW) - were applied in 13 children (7 boys), from 7 to 16 years, with unilateral stroke confi...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2012005000018
更新日期:2013-01-01 00:00:00
abstract::The existence of a benign multiple sclerosis (BMS) form is a controversial subject. Recent studies of these patients reveal different levels of cognitive impairment, despite the apparent preservation of motor function. The objective of this study was to review and analyze a number of publications that discuss the gene...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章,评审
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更新日期:2017-06-01 00:00:00
abstract::A case of carotid-basilar anastomose with persistence of the primitive hypoglossal artery is reported. The authors related aspects of intracranial aneurysm. Anatomical, embryological, physiopathological and angiographical aspects are discussed. ...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1980000300011
更新日期:1980-09-01 00:00:00
abstract:OBJECTIVES:The industrialization process and nervous system cancer (NSC) mortality in a urban region of Brazil. METHOD:From registries of the State System of Data Analysis Foundation (SEADE), 103 males deaths by NSC (ICD-9) in Baixada Santista (BS), from 1980 to 1993 were selected. Mortality ratios were calculated com...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2000000300003
更新日期:2000-06-01 00:00:00
abstract::Alternative surgical procedures to treat unclippable aneurysms of the intracavernous carotid artery include proximal vessel occlusion and trapping. Those techniques, even in patients with rich collateral vessels, are associated with risk of hemodynamic compromise and ischemic complications. Therefore, a safe treatment...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2001000100030
更新日期:2001-03-01 00:00:00
abstract::This work aimed to compare performances on the Timed Up and Go (TUG) test and its subtasks between faller and non-faller older adults with mild cognitive impairment (MCI) and mild Alzheimer's disease (AD). A prospective study was conducted, with 38 older adults with MCI and 37 with mild AD. Participants underwent an a...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/0004-282X20180055
更新日期:2018-06-01 00:00:00
abstract::Intravenous rt-PA is an effective recanalizing treatment for ischemic stroke within 4 and half hours from its onset (Onset-to-Treatment [OTT]), with the best result seen in those treated within 90 minutes OTT. Yet few patients currently are treated in this time frame. From the standpoint of process improvement or a le...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/0004-282X20150047
更新日期:2015-06-01 00:00:00
abstract::We conducted a 320 year retrospective survey of the history and genealogy of a large Brazilian family with SCA7. The ancestral couple was from the State of Ceará, Brazil, and the genealogical tree was composed of 577 individuals, including 217 males (37.6%), 255 females (44.1%) and 105 individuals of unknown sex (18.1...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2006000200010
更新日期:2006-06-01 00:00:00