Abstract:
OBJECTIVE:Increasing use of fertility drugs is considered the primary cause for the recent increase in dizygotic twinning in developed countries. However, dizygotic twinning has also been related to obesity in foreign populations. We sought to confirm this relationship in U.S. pregnancies, which predated widespread use of fertility drugs. METHODS:We analyzed 51,783 pregnancies (561 twin) in the Collaborative Perinatal Project, which took place at 12 hospitals in the United States from 1959 to 1966. The occurrence of twinning was compared according to maternal self-reported prepregnant body mass index (BMI) of less than 20, 20-24.99, 25-29.99, and 30 kg/m(2) or greater, before and after adjustment for confounding factors. RESULTS:There was a statistically significant trend for increased risk of total twinning with increasing BMI (P < .001). The odds of monozygous twinning were not significantly related to BMI, but the odds of dizygous twinning were significantly related to increased BMI. After adjusting for maternal race, age, parity, and height, the odds of dizygous twinning were still significantly elevated among women with a BMI of 30 or more, and the trend for increasing risk of dizygous twinning with increasing BMI was significant (P = .001). The trend for increased twinning with increasing height was also significant. Women in the tallest quartile of height had a significantly increased odds ratio for dizygous twin pregnancies, although not of the same magnitude as women with BMI over 30. CONCLUSION:We confirmed the association of maternal weight and height with dizygotic twinning in a U.S. population among which fertility drugs were not a factor.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Reddy UM,Branum AM,Klebanoff MAdoi
10.1097/01.AOG.0000153491.09525.ddsubject
Has Abstractpub_date
2005-03-01 00:00:00pages
593-7issue
3eissn
0029-7844issn
1873-233Xpii
105/3/593journal_volume
105pub_type
杂志文章abstract:OBJECTIVE:To examine differences in clinical and pathologic characteristics between women undergoing hysterectomy who had had prior tubal sterilization and those who had not. METHODS:One thousand eight hundred fifty-one women undergoing hysterectomy were enrolled as part of a multicenter, prospective cohort study. We ...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/0029-7844(96)00149-4
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:Functional ovarian cysts are a common gynecological problem among women of reproductive age worldwide. When large, persistent, or painful, these cysts may require operations, sometimes resulting in removal of the ovary. Since early oral contraceptives were associated with a reduced incidence of functional ov...
journal_title:Obstetrics and gynecology
pub_type: 评论,杂志文章
doi:10.1097/AOG.0b013e3181b5a547
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To examine the effect of underlying maternal morbidities on the odds of maternal death during delivery hospitalization. METHODS:We used data that linked birth certificates to hospital discharge diagnoses from singleton live births at 22 weeks of gestation or later during 1995-2003 in New York City. Maternal ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e3182a06f4e
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the accuracy of the diagnosis of presumed ectopic pregnancy. METHODS:This was a retrospective cohort analysis at a tertiary care medical center. The patient population was composed of 1) clinically stable pregnant women with human chorionic gonadotropin (hCG) above 2000 mIU/mL and no evidence of ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(02)02142-7
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Pessaries are a treatment option for pelvic organ prolapse, stress urinary incontinence (SUI), and cervical incompetence. An effective pessary is comfortable, corrects the presenting problem, does not cause adverse effects, and is easy to remove. Discomfort and poor fit limit the usefulness of pessaries for ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000002461
更新日期:2018-03-01 00:00:00
abstract::This study was designed to compare the effects of two low-dose triphasic oral contraceptives (OCs) on glucose tolerance and insulin secretion. Fifty-seven women were randomized to receive OCs containing ethinyl estradiol and either levonorgestrel or norethindrone. Ten subjects using nonhormonal contraception served as...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-07-01 00:00:00
abstract::A 68-year-old postmenopausal patient with adenoid cystic carcinoma of the cervic is described. Thirty-two other cases were collected from the literature, and a clinicopathologic analysis for the whole group is presented. The study indicates that a) adenoid cystic carcinoma usually occurs in postmenopausal patients in ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/00006250-197506000-00018
更新日期:1975-06-01 00:00:00
abstract::The histologic diagnoses of premalignant and malignant lesions of the cervix obtained by examining the colposcopically directed biopsy material from 643 patients were compared with those of the surgical material subsequently obtained. The procedures during which samples were acquired included hysterectomy (370), cervi...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1981-08-01 00:00:00
abstract::There are a number of new genetic tests and a variety of recommendations for obstetrician-gynecologists. In recent years, screening of low-risk pregnant women with noninvasive prenatal testing has been proposed as well as universal BRCA1 and BRCA2 screening of all women regardless of risk status. Both proposed genetic...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000000871
更新日期:2015-06-01 00:00:00
abstract::Cultures for Chlamydia trachomatis were obtained from 127 female adolescents (13-17 years of age) evaluated for reported sexual abuse. The rate of positive cultures for C trachomatis in this population was 14% (18 of 127). Neisseria gonorrhoeae was found in 12% (15 of 127) of these patients. All but two of the culture...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract:OBJECTIVE:To define the frequency, risk factors, and outcomes of massive transfusion in obstetrics. METHODS:The State Inpatient Dataset for New York (1998-2007) was used to identify all delivery hospitalizations for hospitals that reported at least one delivery-related transfusion per year. Multivariable logistic regr...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000000021
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To estimate fatal and nonfatal opioid overdose events in pregnant and postpartum women in Massachusetts, comparing rates in individuals receiving and not receiving pharmacotherapy for opioid use disorder (OUD). METHODS:We conducted a population-based retrospective cohort study using linked administrative and...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000002734
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To compare the expression of Cyr61 in normal cycling endometrium with endometrium from women with polycystic ovarian syndrome (PCOS) and endometrial hyperplasia and adenocarcinoma. METHODS:This is a retrospective study of 59 samples of normal and abnormal endometrium. Endometrial biopsies were obtained from ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000269047.46078.28
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:To evaluate whether transvaginal Doppler ultrasound is more valid than transvaginal sonography, magnetic resonance imaging (MRI), and CA 125 in differentiating malignant from benign ovarian tumors. METHODS:Sixty-three patients with ovarian tumors (36 benign and 27 malignant) were studied with transvaginal Do...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:We report a highly exceptional case in which a gonadotroph adenoma was diagnosed in a patient with normal follicle-stimulating hormone (FSH) levels. CASE:A 30-year-old woman with a gonadotroph adenoma presented with hyperstimulation syndrome and normal FSH levels. After treatment of her adenoma she had regu...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000247316.60573.4a
更新日期:2007-02-01 00:00:00
abstract::Unexpected antepartum fetal demise remains one of the most tragic complications of pregnancy. Various approaches to antepartum fetal assessment have been developed as a means of either reassuring the clinician of fetal well-being or identifying potential fetal jeopardy and the need for delivery. As additional high-ris...
journal_title:Obstetrics and gynecology
pub_type: 社论
doi:10.1097/AOG.0000000000002967
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:To compare the accuracy of D&C and office Z-sampler endometrial biopsy in predicting hysterectomy tumor grade in women with endometrial cancer. METHODS:Between September 1987 and July 1994, 183 women with endometrial cancer had D&C or office Z-sampler endometrial biopsy before hysterectomy. RESULTS:One hund...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0029-7844(95)00105-Z
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:To investigate the differences in costs and outcomes of Down syndrome screening using data from the First and Second Trimester Evaluation of Risk (FASTER) Trial. METHODS:Seven possible screening options for Down syndrome were compared: 1) Triple Screen-maternal serum alpha fetoprotein, estriol, and hCG; 2) Q...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000263470.89007.e3
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of an advanced-practice nurse-obstetrician collaborative prenatal practice. METHODS:A group of 194 consecutively enrolled medically low-risk obstetric patients was identified between January 1, 1994 and December 31, 1994 at Neighborhood Pregnancy Care, a collaborative-practice s...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(97)00649-2
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVE:To report our experience with essential thrombocythemia complicating pregnancy. METHODS:Over a 5-year period, we studied 21 women of reproductive age affected by essential thrombocythemia. Diagnoses were based on previously published Polycythemia Vera Study Group criteria. RESULTS:Five of our 21 patients be...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/00006250-199406000-00002
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:A regimen including interferon-alpha has become the standard of care in the treatment of chronic hepatitis C over the last decade. One rare adverse effect associated with the use of interferon-alpha is a granulomatous pulmonary reaction. CASE:A unique case of uterine sarcoidosis associated with the use of i...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000157764.44292.aa
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVE:To estimate if there were dietary or socioeconomic factors associated with preterm premature rupture of membranes (PROM). METHODS:In this case-control study, women with preterm PROM (n = 46) were compared with healthy pregnant women matched for gestational age and vitamin supplementation. Measurements includ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(02)02380-3
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:To test whether repeating Doppler studies of the uteroplacental circulation late in gestation will improve the test's power for predicting pregnancy-induced hypertension and fetal growth restriction (FGR), and whether analysis based on a combination of quantitative and qualitative assessments of the uterine a...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章
doi:10.1016/0029-7844(95)00006-D
更新日期:1995-04-01 00:00:00
abstract:BACKGROUND:Human metapneumovirus has recently been recognized as an important cause of severe respiratory viral infections and of viral infections in patients admitted to intensive care units. Little is known about the course of this infection in pregnancy. CASE:A late-preterm primigravid woman was admitted to the int...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000002165
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To collect data from nine European countries for cases of obstetric hemorrhage between 2000 and 2004 in which recombinant activated factor VII (rFVIIa) was used. METHODS:The cases were identified through national surveys. Standardized case report forms included sociodemographic details, past medical and obst...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000288515.48066.99
更新日期:2007-12-01 00:00:00
abstract::Two hundred seven high-risk patients were studied prospectively by standardized nonstressed fetal heart rate monitoring followed immediately by contraction stress testing (CST). Of the 604 combined procedures examined, 90.2% of nonstress tests (NST) were interpreted as reactive; none was associated with a positive CST...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1980-05-01 00:00:00
abstract:BACKGROUND:Although the clinical presentation and imaging techniques can raise suspicion for placenta previa percreta, this potentially catastrophic condition may remain undiagnosed or its extent underappreciated until delivery. The decision to proceed with definitive surgery in cases of placenta previa percreta should...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(97)81425-1
更新日期:1997-05-01 00:00:00
abstract::Phenylketonuria (PKU) is an autosomal recessive disorder of phenylalanine (Phe) metabolism characterized by a deficiency of the hepatic enzyme, phenylalanine hydroxylase, an enzyme responsible for the conversion of phenylalanine to tyrosine, and elevated levels of Phe and Phe metabolite. All women with PKU or hyperphe...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e3181c6f93d
更新日期:2009-12-01 00:00:00
abstract::: The initial visit for screening and the provision of reproductive preventive health care services and guidance should take place between the ages of 13 years and 15 years. The initial reproductive health visit provides an excellent opportunity for the obstetrician-gynecologist to start a patient-physician relationsh...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000446826.46833.c0
更新日期:2014-05-01 00:00:00
abstract::This month, we focus on current research in preterm birth prevention. Dr. Andrews discusses recent publications, and each is concluded with a "bottom line" that is the take-home message. The complete reference for each can be found in on this page, along with direct links to the abstracts. ...
journal_title:Obstetrics and gynecology
pub_type: 评论,杂志文章
doi:10.1097/AOG.0b013e31829e41fc
更新日期:2013-08-01 00:00:00