Vertical transmission of feline immunodeficiency virus.

abstract：:The surface envelope glycoprotein gp46 of the human T cell leukemia virus type 1 elicits a strong immune response. Its protective role against HTLV-1 infection in animal models is well established, suggesting that recombinant envelope glycoproteins or synthetic peptides could be used as an effective vaccine. However, ...

journal_title：AIDS research and human retroviruses

authors： Tallet B,Astier-Gin T,Moynet D,Londos-Gagliardi D,Guillemain B

更新日期：2001-03-01 00:00:00

abstract：:We partially purified the human immunodeficiency virus (HIV) glycoprotein gp41 from infected H9 cells by immunoaffinity chromatography using a column containing the M25 monoclonal antibody (diMarzo-Veronese et al., 1985). A pH 11.5 buffer worked best for eluting the glycoprotein from this column. The eluted gp41 was u...

journal_title：AIDS research and human retroviruses

authors： Zweig M,Showalter SD,Bladen SV,Gilden RV,Arthur LO,Robey WG,Nara PL,Fischinger PJ

更新日期：1988-02-01 00:00:00

abstract：:Eight fragments derived from the HIV-1 pol gene were expressed as recombinant polypeptides in Escherichia coli. The fragments were from the portion of the pol gene that encodes the reverse transcriptase. The expressed peptides were analyzed immunologically with sera from HIV-1-infected individuals. Three distinct immu...

journal_title：AIDS research and human retroviruses

authors： Padberg C,Nowlan S,Mermer B

更新日期：1989-02-01 00:00:00

abstract：:In an attempt to develop an immunization strategy to induce mucosal and circulatory antibodies against SIV antigens, we have investigated the potential of attenuated recombinant vaccinia virus to deliver SIV antigens (gp160 of SIVmac239) to mucosal surfaces of mice. After systemic or mucosal (intragastric, intranasal,...

journal_title：AIDS research and human retroviruses

authors： Moldoveanu Z,Vzorov AN,Huang WQ,Mestecky J,Compans RW

更新日期：1999-11-01 00:00:00

abstract：:Six morphine-dependent and two control macaques were infected in an SIV/SHIV nonhuman primate model of AIDS. Three animals in the morphine group rapidly developed clinical disease and died within the timeframe of this study. The sequence evolution of nef in plasma virus was assessed at 4, 12, and 20 weeks postinfectio...

journal_title：AIDS research and human retroviruses

authors： Noel RJ,Toro-Bahamonde A,Marrero-Otero Z,Orsini S,Verma AS,Kumar R,Kumar A

更新日期：2006-08-01 00:00:00

abstract：:Changes in neutralizing antibody (NA) titers in stored sera collected over 5 years from 10 participants in the Multicenter AIDS Cohort Study (MACS) were evaluated. The participants were HIV-1 infected on enrollment in the MACS, and remained AIDS free during the 5-year study interval. Seven viruses derived from molecul...

journal_title：AIDS research and human retroviruses

authors： Quinnan GV Jr,Zhang PF,Fu DW,Dong M,Margolick JB

更新日期：1998-07-20 00:00:00

abstract：:Murine monoclonal antibodies (MAbs) raised against a recombinant nef protein fragment of human immunodeficiency virus type 1 (HIV-1) strain BH10 were characterized by an epitope mapping system using overlapping decapeptides. Four different immunogenic regions were identified. Ten human HIV-1-positive sera were tested ...

journal_title：AIDS research and human retroviruses

authors： Schneider T,Harthus HP,Hildebrandt P,Niedrig M,Bröker M,Weigelt W,Beck A,Pauli G

更新日期：1991-01-01 00:00:00

abstract：:Transition from latency to active replication is a crucial stage for the process of human immunodeficiency virus type 1 (HIV-1) infection and life cycle. HIV-1 replication in latently infected cells can be strongly induced by the cytokine tumor necrosis factor alpha (TNF-alpha) and the proliferation-arresting chemical...

journal_title：AIDS research and human retroviruses

authors： Moulton S,Pantazis P,Epstein JS,Sadaie MR

更新日期：1998-01-01 00:00:00

abstract：:The HIV epidemic in Russia, one of the world's fastest growing, has been concentrated mostly among people who inject drugs (PWID). We sought to explore the epidemiology of the epidemic in St. Petersburg by sampling from the highest risk groups of PWID and men who have sex with men (MSM) and use viral sequencing data t...

journal_title：AIDS research and human retroviruses

authors： Dukhovlinova E,Masharsky A,Toussova O,Verevochkin S,Solovyeva T,Meringof M,Paintsil E,White E,Barbour R,Heimer R,Kozlov A

更新日期：2015-06-01 00:00:00

abstract：:CD4(+) T cell help is important for the functionality of CD8(+) cytotoxic T-lymphocytes (CTLs) in limiting viral replication and may contribute to mediation of apparent resistance to HIV-1 infection in exposed seronegative (ESN) individuals. Using five HIV-1 antigens in an intracellular cytokine assay, the presence of...

journal_title：AIDS research and human retroviruses

authors： Kebba A,Kaleebu P,Serwanga J,Rowland S,Yirrell D,Downing R,Gilmour J,Imami N,Gotch F,Whitworth J

更新日期：2004-01-01 00:00:00

abstract：:Macrophages are a preferred target for sexually transmitted human immunodeficiency virus type 1 (HIV-1) isolates that use CCR5 as a coreceptor in combination with CD4. To assess whether the susceptibility of MDMs to infection by an R5 isolate was influenced by CD4 and/or CCR5 expression, levels of membrane CD4 or CCR5...

journal_title：AIDS research and human retroviruses

authors： Pesenti E,Pastore C,Lillo F,Siccardi AG,Vercelli D,Lopalco L

更新日期：1999-07-20 00:00:00

abstract：:Simian species of Asian and African origin are naturally infected with the simian T cell leukemia virus type I (STLV-I). Like the closely related human T cell leukemia virus type I (HTLV-I), STLV-I is primarily cell associated, and typical infections exhibit low viral burdens. Four macaques experimentally inoculated w...

journal_title：AIDS research and human retroviruses

authors： Liska V,Fultz PN,Su L,Ruprecht RM

更新日期：1997-09-01 00:00:00

abstract：:To investigate how human immunodeficiency virus type 1 (HIV-1) escapes from antibodies directed against the neutralization domain in the third variable region (V3) of gp120, we examined precisely which amino acid contributed to antibody binding. From six HIV-1-infected individuals, sequential sera were tested for anti...

journal_title：AIDS research and human retroviruses

authors： Langedijk JP,Zwart G,Goudsmit J,Meloen RH

更新日期：1995-10-01 00:00:00

abstract：:Jurkat cells stably expressing high levels of the HIV-1 Tat protein were generated after transfection with an Epstein-Barr virus-based episomal replicon and selection in hygromycin B. The Jurkat Tat transfectants exhibited a longer doubling time when compared to Jurkat cells or Jurkat cells transfected with the contro...

journal_title：AIDS research and human retroviruses

authors： Purvis SF,Jacobberger JW,Sramkoski RM,Patki AH,Lederman MM

更新日期：1995-04-01 00:00:00

abstract：:The combination of didanosine (ddI) and lamivudine (3TC) is attractive considering its low cost, potency, tolerability, and convenience (once daily administration), but it is not recommended as first-line therapy for HIV infection. A prospective, multicenter, open, comparative trial was conducted in HIV-infected, anti...

journal_title：AIDS research and human retroviruses

authors： Sánchez-Conde M,Palacios R,Sanz J,Rodríguez-Novoa S,Rivas P,Santos J,Sola J,Asensi V,de Mendoza C,Estrada V,Barreiro P,González-Lahoz J,Jiménez-Nacher I,Soriano V

更新日期：2007-10-01 00:00:00

abstract：:The advent of antiretroviral treatment (ART) has resulted in a dramatic reduction in AIDS-related morbidity and mortality. However, the emergence and spread of antiretroviral drug resistance (DR) threaten to negatively impact treatment regimens and compromise efforts to control the epidemic. It is recommended that sur...

journal_title：AIDS research and human retroviruses

authors： Cheriro W,Kiptoo M,Kikuvi G,Mining S,Emonyi W,Songok E

更新日期：2015-12-01 00:00:00

abstract：:We tested the effect of three linear or two loop peptides derived from the V3 region of the HTLV-III BH10 clone or the SF2 strain of human immunodeficiency virus type 1 on IL-2-driven T cell proliferation. V3-BH10, which consists of 42 amino acids and has a loop structure, suppressed IL-2-driven proliferation of all I...

journal_title：AIDS research and human retroviruses

authors： Sakaida H,Murakami T,Kawamata S,Hattori T,Uchiyama T

更新日期：1997-01-20 00:00:00

abstract：:The surface molecule CD4 plays a key role in initiating cellular entry by the human immunodeficiency virus type 1 (HIV-1), and it is now recognized as acting synergistically with select chemokine receptors (coreceptors) in the infection process. The present study was undertaken to determine whether the extracellular r...

journal_title：AIDS research and human retroviruses

authors： Esser U,Speck RF,Deen KC,Atchison RE,Sweet R,Goldsmith MA

更新日期：2000-11-20 00:00:00

abstract：:EpiMatrix/HIV, a tool that is currently available on the World Wide Web, enables researchers to screen HIV proteins for potential MHC ligands. We have performed a comparison of EpiMatrix predictions to 158 published allotype-specific HLA-associated peptides (MHC ligands) derived from 133 proteins. The top 10 ranked Ep...

journal_title：AIDS research and human retroviruses

authors： De Groot AS,Jesdale BM,Szu E,Schafer JR,Chicz RM,Deocampo G

更新日期：1997-05-01 00:00:00

abstract：:HIV infection is a risk factor for the tumorigenesis including non-AIDS-defining cancers such as those of the gastrointestinal tract. However, the mechanisms underlying such cancer outgrowth are still unknown. Furthermore, combined HIV/cancer studies are difficult to evaluate using primate models or in the clinical pa...

journal_title：AIDS research and human retroviruses

authors： Lu R,Wu S,Zhang Y,Xia Y,Huelsmann EJ,Lacek AT,Nabatiyan A,Richards MH,Narasipura SD,Lutgen V,Chen H,Kaufman HL,Chen D,Al-Harthi L,Zloza A,Sun J

更新日期：2014-07-01 00:00:00

abstract：:The emergence of T cell-tropic, syncytium-inducing (T-tropic/SI) HIV-1 variants from the background of macrophage-tropic, non-syncytium-inducing (M-tropic/NSI) strains is associated with disease progression in infected individuals. HIV89.6 is a primary isolate with a transitional phenotype: like M-tropic strains it re...

journal_title：AIDS research and human retroviruses

authors： Smyth RJ,Yi Y,Kim FM,Collman RG

更新日期：1997-06-10 00:00:00

abstract：:The efficacy, safety, and pharmacokinetics of three doses of tipranavir/ritonavir (TPV/r) in highly treatment-experienced human immunodeficiency virus (HIV)-1-infected patients with protease inhibitor (PI)-resistant isolates were evaluated. A 24-week multicenter, double-blind, randomized, dose-finding trial was conduc...

journal_title：AIDS research and human retroviruses

authors： Gathe JC Jr,Pierone G,Piliero P,Arasteh K,Rubio R,Lalonde RG,Cooper D,Lazzarin A,Kohlbrenner VM,Dohnanyi C,Sabo J,Mayers D

更新日期：2007-02-01 00:00:00

abstract：:We investigated a strategy for gene therapy, intracellular expression of anti-HIV-1 Rev single-chain variable fragments (SFvs), in promonocytic (U1) and T (ACH-2) cell lines latently infected with HIV-1. The cellular and molecular mechanisms leading to activation of latent integrated HIV-1 provirus in U1 and ACH-2 cel...

journal_title：AIDS research and human retroviruses

authors： Ho WZ,Lai JP,Bouhamdan M,Duan L,Pomerantz RJ,Starr SE

更新日期：1998-11-20 00:00:00

abstract：:This study seeks to analyze nearly full-length viral genomes for distinct genetic characteristics that are unique to local or regional strains and to identify regions that have high variability or are highly conserved. Nearly full length sequences of seven HIV-1 samples were obtained to ascertain the circulating subty...

journal_title：AIDS research and human retroviruses

authors： Roye ME,Amarakoon II,Hamilton CL,Eyzaguirre LM,Figueroa P,Carr JK

更新日期：2011-01-01 00:00:00

abstract：:DNA vaccines have the potential of giving rise to a potent cell-mediated immune response by inducing intracellular synthesis and subsequent antigenic presentation of encoded antigens. We have tested a DNA vaccine specific for human immunodeficiency virus type 1 (HIV-1) by the injection of animals with expression plasm...

journal_title：AIDS research and human retroviruses

authors： Okuda K,Bukawa H,Hamajima K,Kawamoto S,Sekigawa K,Yamada Y,Tanaka S,Ishi N,Aoki I,Nakamura M

更新日期：1995-08-01 00:00:00

abstract：:Accurate methods for cross-sectional incidence estimation are needed for HIV prevention research. The Limiting Antigen Avidity (LAg-Avidity) assay has been marketed by two vendors, Maxim Biomedical and Sedia BioSciences Corporation. Performance differences between the two versions of the assay are unknown. We tested a...

journal_title：AIDS research and human retroviruses

authors： Schlusser KE,Konikoff J,Kirkpatrick AR,Morrison C,Chipato T,Chen PL,Munjoma M,Eshleman SH,Laeyendecker O

更新日期：2017-06-01 00:00:00

abstract：:Osteopenia is a common and debilitating side-effect of HAART, yet little is known concerning the effects of HAART on bone metabolism. We reported previously that zidovudine (AZT) stimulates osteoclastogenesis in vitro and causes osteopenia in mice. Here, we confirmed that the AZT-induced osteoclastogenesis is dependen...

journal_title：AIDS research and human retroviruses

authors： Pan G,Kilby M,McDonald JM

更新日期：2006-11-01 00:00:00

abstract：:HIV was first described in Kenya in 1984-1985. Currently, Kenya has an estimated HIV-1 prevalence of 6.2%. With the introduction of antiretroviral drugs, the survival of most HIV patients has been prolonged markedly. However, this is greatly threatened by increasing rates of antiretroviral dug resistance, which may ev...

journal_title：AIDS research and human retroviruses

authors： Onsongo S,Abidi SH,Khamadi S,Shah R,Kageha S,Ojwang P,Ali S,Okinda N

更新日期：2016-03-01 00:00:00

abstract：:Cytotoxic T cell determinants should be an important component of an anti-human immunodeficiency virus (HIV) vaccine. The epitopes of proteins can be defined with short synthetic peptides for class I-restricted CTLs. An immunodominant CTL epitope from the HIV-1 IIIB envelope protein gp160 comprising 15 amino acids (re...

journal_title：AIDS research and human retroviruses

authors： Achour A,Lemhammedi S,Picard O,M'Bika JP,Zagury JF,Moukrim Z,Willer A,Beix F,Burny A,Zagury D

更新日期：1994-01-01 00:00:00

abstract：:The objectives of this study were to evaluate the performance of parallel rapid HIV testing and the presence of HIV-associated risk factors in pregnant women with unknown HIV status in Baja California, Mexico. Pregnant women attending the delivery unit or the prenatal clinic at Tijuana General Hospital had blood drawn...

journal_title：AIDS research and human retroviruses

authors： Viani RM,Araneta MR,Spector SA

更新日期：2013-03-01 00:00:00