Abstract:
:In a short historical review of the outstanding changes occurred in the whole of endocrinology and particularly in Chile over the last 60 years -with the background of an infant mortality drop from 200 per thousand in 1940 to 8 per thousand today and a mean life expectancy increase from 42 to 76 years- the author outlines major achievements in this country. He comments on the use in former days of biological tests on urine extract to measure hormones for diagnostic procedures replaced by hormone determinations in blood by radioimmunoassays; today's medication with synthetic hormones instead of opotherapeutic preparations obtained from organ extracts; the identification of new hormones, receptors and new knowledge that enables us to understand the role of neurotransmitters and neuromodulators, the interaction of neurological, endocrine and immunological systems and the involvement of stress in various diseases. Finally the description of DNA and the international cooperative project to establish the human genome map with unpredictable potential applications in medicine. The author underlines the importance of collaborative work in all branches of medicine, often making cooperation more effective than competition. The enormous expansion of biological information demands that direct application of scientific knowledge to clinical medicine is prevented as being insufficient for an optimal clinical judgment, since a bio-psychosociological perspective of the patient and the doctor's clinical experience are essential factors in the doctor-patient relationship.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Jadresic Adoi
10.4067/s0034-98872005000600017subject
Has Abstractpub_date
2005-06-01 00:00:00pages
729-36issue
6eissn
0034-9887issn
0717-6163pii
S0034-98872005000600017journal_volume
133pub_type
历史文章,杂志文章abstract::We report a 74-year-old male with liver metastases from a neuroendocrine tumor (NET) of unknown origin. Conventional imaging studies with ultrasound, computed tomography colonoscopy and Positron emission tomography-computed tomography (PET/CT) with 18Fluor odeoxyglucose did not identify the site of origin of the prima...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872009000400012
更新日期:2009-04-01 00:00:00
abstract::We evaluated the role of oxygen free radicals in the induction of acute stress gastric ulcer in rats. After 12 hr of immobility, ulcers of up to 4 mm were observed in the gastric mucosa. Pretreatment with allopurinol, a xanthine oxidase inhibitor, produced a significant reduction in the number and size of lesions (p <...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:Determination of Alanine aminotransferase serum levels ([ALT]s) is a sensitive ana reliable test for liver diseases. AIM:To report the prevalence of abnormal [ALT]s in Chilean population and to identify associated variables. METHODS:We analyzed data from a random sub-sample of 2,794 adults surveyed during ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872013000700011
更新日期:2013-07-01 00:00:00
abstract::In biomedical measurement, comparisons between two instruments or between a new instrument and the gold standard is commonly needed to evaluate the reliability and validity of the instruments. Such studies are frequently analyzed using statistics that are inappropriate for studying concordance. This article reviews th...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND:Scientific Ethics is the theory and praxis of decisions. Philosophical Ethics is presented as the theory and praxis of the good. As the good differs among cultures, Philosophical Ethics is dependent on the endo-cultural good conception. The decision (included that one of adhesion or not to a world vision) de...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::A 62 years old male with a slowly progressive focal myopathy is presented. He had noticed weakness in the lower limbs for three years and weakness in the upper limbs for one year. He had bilateral atrophy of quadriceps and biceps muscles, absence of knee jerks and hypertrophy of the calves. Needle EMG showed myopathic...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Hürthle cells can be found in non malignant thyroidal diseases such as Basedow Graves and Hashimoto diseases. When Hürthle cells comprise more the 75% of cellularity, they become a neoplasm. There are malignant variants of these neoplasms, constituted by follicular and papillary Hürthle cell carcinomas. AIM...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract::The functional differentiation of mammary epithelial cells requires specific hormones, growth factors and chemical signals of the cellular environment. These signals consist in cell communication with the extracellular matrix and cell-cell interactions which through an intrincated mechanism lead to the events that tri...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:Framingham risk score (FRS) has limitations and can underestimate risk. Carotid ultrasound to measure intima media thickness or plaques is recommended for cardiovascular risk assessment. AIM:To determine the prevalence of subclinical atherosclerosis in asymptomatic subjects classified as low and intermediat...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872016000100005
更新日期:2016-01-01 00:00:00
abstract::The aim of this study was to assess the predictive value for mortality of admission and daily APACHE II score, mortality due to multiple organ failure and the Organ Failure Score in patients with acute hepatic failure. We retrospectively studied 15 such patients admitted to an intensive care unit. Thirteen patients di...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::A national network including 114 blood banks and laboratories performs screening for HIV infection on approximately 250,000 blood donors a year. This represents 100% coverage of blood transfusions performed in Chile. Up to December 1990. 4956 samples had been sent to the National Reference Center for AIDS for suppleme...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::In an open, pilot study, the efficacy and safety of ursodeoxycholic acid (UDCA) in the treatment of intrahepatic cholestasis of pregnancy was investigated. Four patients received 1 g/day of UDCA during 20 days and another 2 patients received 2 identical periods of treatment separated by a 14-day interval free of drug....
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract:UNLABELLED:Circulating concentrations of the high affinity growth hormone binding protein (GHBP) may be a marker of GH receptor density as well as GH sensitivity. GOAL:To determine values of GHBP for a normal Chilean pediatric population. METHODS:We determined GHBP levels in 73 males and 73 females between 4 to 15.5 ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:On February 27, 2010 a powerful earthquake followed by a tsunami stroke Chile. The study of mortality during this emergency can provide important public health information. AIM:To describe the main characteristics of people who died during the earthquake and the following three months. MATERIAL AND METHODS...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000600006
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:There is a very strong documented correlation between the appearance of cancer cells in blood and occurrence of metastasis in gastrointestinal cancer. AIM:To determine MUC1, CK19, CK20 and CEA mRNA expression in bone marrow of patients with gallbladder cancer and evaluate its clinical significance. MATERIA...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract::The earth of ornamental plants is one of the main reservoirs of Aspergillus type of fungi in hospital areas. We studied 174 ornamental interior plants from a hospital at Santiago. Samples were obtained from the soil surface and sowed in Sabouraud-glucose agar, adding streptomycin and G-penicillin. After 72 h of cultur...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::We report a 16-year-old boy, who suffered a right vent ride penetrating injury caused by a sharp blade that evolved to cardiac tampon. He underwent surgery and was discharged four days later. Thirteen days later, a cardiac murmur was found. An echocardiography showed an aorta-right ventricular fistula. Surgical closur...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010000200010
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Twenty to twenty two percent of work related accidents have a direct or indirect relationship with recent alcohol use. AIM:To detect recent alcohol or drug use in patients who required hospitalization for severe work related accidents. PATIENTS AND METHODS:Blood and urine samples were obtained from patient...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:In Chile, Thyroid cancer (TC) is included in a list of diseases that have a guaranteed access to treatment, endorsed by the Ministry of Health. The care burden of the disease will depend on its incidence. AIM:To estimate the incidence of TC in Chilean patients with access to thyroid surgery and describe its...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872020000500573
更新日期:2020-05-01 00:00:00
abstract::Geographical hematology of Bernard and Ruffie, or Hemato-sero-anthropology, intends to establish relationships between hereditary genetic characters of the blood and human races. Blood groups, haptoglobins, abnormal hemoglobin and other biological traits such as color vision are related to the origin of human races, t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Acute appendicitis is the most common non obstetric surgical emergency during pregnancy. AIM:To asses our experience in the diagnosis and management of acute appendicitis occurring during pregnancy. PATIENTS AND METHODS:Data from all pregnant patients who were subjected to an appendectomy for a suspected a...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006000200002
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Worldwide, smoking is the main avoidable cause of death among adults. AIM:To study smoking habits among health care workers in Chile. MATERIAL AND METHODS:A national survey about smoking among subjects working in the Chilean Ministry of Health. An anonymous and self administered enquiry was used. RESULTS:...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872004000200013
更新日期:2004-02-01 00:00:00
abstract::We report a 56 years old male patient presenting with a sympathetic denervation of the right upper limb due to an apical lung cancer. Vasomotor paralysis of the limb was objectively documented with a contact termography. The clinical presentation of this patient was unusual, considering that the alteration occurred wi...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Despite non absorbable antibiotics and neomycin may have antagonistic effects on intestinal bacterial environment, both have synergistic effects in the treatment of hepatic encephalopathy. This could be due to their action on different enteric flora or a neomycin induced carbohydrate malabsorption. AIM:To i...
journal_title:Revista medica de Chile
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-04-01 00:00:00
abstract::We report a 61 years old male presenting with a right cerebral infarction, along with a type I persistent left proatlantal artery (PA), which is a form of primitive carotid-basilar anastomosis. The patient had an absence of the ipsilateral vertebral artery (VA) and hypoplasia of the contralateral VA, while the basilar...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872015000800018
更新日期:2015-08-01 00:00:00
abstract::Background The treatment of choice of newly diagnosed multiple myeloma (NDMM) is an induction with proteasome inhibitors followed autologous stem cell transplantation (HSCT). Since 2013, the treatment of these patients in the public system is based on CTD (cyclophosphamide, thalidomide, and dexamethasone). Aim To eval...
journal_title:Revista medica de Chile
pub_type: 杂志文章,多中心研究
doi:10.4067/S0034-98872019001201561
更新日期:2019-12-01 00:00:00
abstract::One hundred and twenty consecutive patients with liver cirrhosis and ascites were prospectively studied in order to analyze the frequency, clinical and bacteriological features, recurrence, and prognosis of spontaneous bacterial peritonitis (SBP). Two variants of SBP were defined: culture positive SBP and culture nega...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-03-01 00:00:00
abstract::Approximately, 10% of cirrhotic patients with ascites become refractory to medical treatment, a condition that reduces overall survival. TIPS is a therapeutic alternative for the management of refractory ascites. It corrects sinusoidal portal hypertension, becoming a rational and relatively safe therapeutic approach. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1999-10-01 00:00:00
abstract::Platelet Rich Plasma (PRP) is used in musculoskeletal lesion surgery, including muscle, bone, tendons and ligaments. PRP might accelerate the healing process and the integration of the graft, allowing an earlier return to sports activities of patients. PRP is obtained from autologous blood, which is centrifuged, obtai...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872013001000011
更新日期:2013-10-01 00:00:00
abstract::We analyzed 33 patients with recurring nodular goiter (from a population of 2,500 operated patients). Recurrence occurred 0.7 to 12 years after surgery. T4, T3, TSH, perchlorate and TRH tests were performed in 18. Results were similar to those in 13 operated patients without recurrence. Administration of thyroid hormo...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00