Chemotherapy in brain metastases.

abstract：OBJECTIVE:Intracerebral clysis is a drug delivery technique that depends on convection-enhanced microinfusion to achieve therapeutic drug levels within the brain. In this study, brain tumor-bearing rats were treated with topotecan delivered systemically and by the intracerebral clysis method. Our objective was to deter...

journal_title：Neurosurgery

authors： Kaiser MG,Parsa AT,Fine RL,Hall JS,Chakrabarti I,Bruce JN

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:To examine the anatomy of the infraorbital canal and foramen and the angles at which a radiofrequency probe must be directed to enter the infraorbital foramen and canal, as a guide to performing radiofrequency ablation of the infraorbital nerve in patients with relative or absolute contraindications to lesion...

journal_title：Neurosurgery

authors： Rahman M,Richter EO,Osawa S,Rhoton AL Jr

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To describe a procedure for Leksell gamma knife (LGK) radiosurgery in a lateral position, for treatment of far-lateral intracranial lesions. METHODS:Positioning of the patient in the lateral decubitus position during LGK treatment switches the x and y axis coordinates. This increases the range of the x axis ...

journal_title：Neurosurgery

authors： Massager N,Régis J,Porcheron D,Devriendt D,Desmedt F,Levivier M

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To define the factors of importance for the obliteration of cerebral arteriovenous malformations (AVMs), thus making a prediction of the probability for obliteration possible. METHODS:In 945 AVMs of a series of 1319 patients treated with the gamma knife during 1970 to 1990, the relationship between patient, ...

journal_title：Neurosurgery

authors： Karlsson B,Lindquist C,Steiner L

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Schwannomas that arise from the trigeminal nerve are rare and are usually managed by surgical resection. The role of radiosurgery in the care of patients with these basal tumors remains to be defined. METHODS:We reviewed the clinical presentation, management, and outcomes for 16 trigeminal schwannoma patient...

journal_title：Neurosurgery

authors： Huang CF,Kondziolka D,Flickinger JC,Lunsford LD

更新日期：1999-07-01 00:00:00

abstract：:Arterial stenoses and/or occlusions in moyamoya disease are mainly localized intracranially, although some instances of stenotic lesions of the extracranial arteries have been reported in some autopsy cases. We have reviewed the angiograms of 66 patients with moyamoya disease to investigate whether stenotic lesions ar...

journal_title：Neurosurgery

authors： Hoshimaru M,Kikuchi H

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:To describe the incidence and causes of pediatric head, spinal cord, and peripheral nerve injuries in an urban setting and to assess the implications of these data for injury prevention programs. METHODS:Pediatric deaths and hospital admissions secondary to neurological trauma included in the Northern Manhat...

journal_title：Neurosurgery

authors： Durkin MS,Olsen S,Barlow B,Virella A,Connolly ES Jr

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Several studies have explored the effect of overlapping surgery on patient outcomes, but impact of surgical overlap during wound closure has not been studied. OBJECTIVE:To examine the association of overlap during wound closure and suture time overlap (STO) with patient outcomes in a heterogeneous neurosurg...

journal_title：Neurosurgery

authors： Glauser G,Agarwal P,Ramayya AG,Chen HI,Lee JYK,Schuster JM,Osiemo B,Goodrich S,Smith LJ,McClintock SD,Malhotra NR

更新日期：2019-11-01 00:00:00

abstract：:Anterior cervical instrumentation as an adjunct to bone fusion has an important role in cervical spine surgery. Posterior vertebral body cortex purchase is strongly recommended in the use of the Caspar system, although few biomechanical data exist to validate this requirement. In this study, Caspar screws were placed ...

journal_title：Neurosurgery

authors： Maiman DJ,Pintar FA,Yoganandan N,Reinartz J,Toselli R,Woodward E,Haid R

更新日期：1992-12-01 00:00:00

abstract：:Our experience with progressive unilateral hydrocephalus in children and the pathophysiology of nonneoplastic obstruction of the foramen of Monro has been analyzed. The status of the foramen of Monro in either congenital or acquired progressive unilateral hydrocephalus was classified into the following four categories...

journal_title：Neurosurgery

authors： Oi S,Matsumoto S

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:Facial nerve paresis and hearing loss are common complications after vestibular schwannoma surgery. Experimental and clinical studies point to a beneficial effect of nimodipine and hydroxyethyl starch for preservation of cochlear nerve function. A retrospective analysis was undertaken to evaluate the effect o...

journal_title：Neurosurgery

authors： Strauss C,Romstöck J,Fahlbusch R,Rampp S,Scheller C

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Targeted stereotactic radiosurgery (SRS) with sparing of the residual pituitary is the traditional radiosurgical method for pituitary adenomas. Whole-sella SRS is an alternative choice for radiologically indeterminate or large adenomas, the safety and efficacy of which has yet to be determined. OBJECTIVE:To...

journal_title：Neurosurgery

authors： Taylor DG,Janssen A,Ding D,Xu Z,Mehta GU,Liscak R,Kano H,Kosak M,Martinez-Moreno N,Hobbs L,Chen CJ,Grills IS,Mathieu D,Lunsford LD,Vance ML,Sheehan JP

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:Gliomatosis cerebri is an enigmatic diffuse brain neoplasm whose prognosis is grim. We reviewed data for patients with gliomatosis who were treated at the University of California, San Francisco, during a 10-year period. Our focus was on presentation, radiological and pathological features, and outcomes. MET...

journal_title：Neurosurgery

authors： Vates GE,Chang S,Lamborn KR,Prados M,Berger MS

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The lower thoracic spine is a complicated area within the vertebral column because of its anatomic complexity and inaccessibility. A variety of surgical procedures have been applied to access lower thoracic spinal lesions. When hard compressive pathologies are located on the ventral side of the dura, existin...

journal_title：Neurosurgery

authors： Lee SE,Jahng TA,Chung CK,Kim HJ

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:We evaluated and analyzed the effect of superficial temporal artery to middle cerebral artery bypass for internal carotid artery occlusion on pure motor function using motor activation single photon emission computed tomography. METHODS:Motor activation single photon emission computed tomographic (SPECT) ima...

journal_title：Neurosurgery

authors： Kawaguchi S,Noguchi H,Sakaki T,Morimoto T,Hoshida T,Yonezawa T,Imai T,Ohishi H

更新日期：1997-11-01 00:00:00

abstract：:The anatomic reorganization of the subnucleus that controls the stylohyoid muscle (the stylohyoid subnucleus) within the brain stem facial nucleus was studied after regeneration of the facial nerve in adult rats. Horseradish peroxidase was injected into the right stylohyoid muscle 3 to 21 months after transection and ...

journal_title：Neurosurgery

authors： Fernandez E,Pallini R,Marchese E,Lauretti L,La Marca F

更新日期：1995-09-01 00:00:00

abstract：:Estimation of cerebrospinal fluid (CSF) outflow resistance (Ro) using a bolus injection method was carried out under normal conditions and in a state of artificially increased elastance produced by saline loading into the CSF space. These values of Ro were compared with Ro estimated by the steady state infusion method...

journal_title：Neurosurgery

authors： Takizawa H,Gabra-Sanders T,Miller JD

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:Cerebral cavernous malformations (CCMs) affect more than one million Americans, predisposing them to a lifetime risk of hemorrhagic stroke and epilepsy. A potential role of the immune response in this disease has not been postulated previously but is compelling given the unique antigenic milieu of CCM lesions...

journal_title：Neurosurgery

authors： Shenkar R,Shi C,Check IJ,Lipton HL,Awad IA

更新日期：2007-10-01 00:00:00

abstract：:Meningiomas have a wide range of biological potential and clinical behavior. Histological findings are helpful in recognizing the malignant potential of a given tumor, but often fail to correlate with gross features, liability of recurrence, and extent of associated cerebral edema. To find alternate approaches to impr...

journal_title：Neurosurgery

authors： Crone KR,Challa VR,Kute TE,Moody DM,Kelly DL Jr

更新日期：1988-12-01 00:00:00

abstract：:We present two cases of false aneurysm after carotid endarterectomy with primary arteriotomy closure. In both cases, infection appeared to be the precipitating cause. Both lesions were repaired with a saphenous vein patch graft, but infection in one patient persisted, and recurrence of a false aneurysm required ligati...

journal_title：Neurosurgery

authors： Branch CL Jr,Davis CH Jr

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Spinal cord cavernous malformations (CMs) are associated with 2 types of angiographically occult "cryptic venous anomalies," which differ in location with respect to the spinal cord. The anatomic distinction between superficial and intramedullary is important in that the latter heighten the risks of CM resec...

journal_title：Neurosurgery

authors： Pearl MS,Chen JX,Gregg L,San Millàn D,Belzberg A,Jallo G,Gailloud P

更新日期：2012-09-01 00:00:00

abstract：:Expansive granulomatous lesions in the posterior cranial fossa are rare and have not been reported in conjunction with Lyme disease. We report a patient with verified Borrelia burgdorferi infection who developed a tumor in the cerebellopontine angle. Rapid growth of the tumor led to signs of cerebral compression and t...

journal_title：Neurosurgery

authors： Mokry M,Flaschka G,Kleinert G,Kleinert R,Fazekas F,Kopp W

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Although transarterial regional hypothermia is an attractive alternative to general hypothermia, its efficacy and underlying mechanisms remain unclear. OBJECTIVE:To confirm transarterial regional hypothermia therapeutic effects on ischemia/reperfusion (I/R) injury and to elucidate the mechanisms responsible...

journal_title：Neurosurgery

authors： Kurisu K,Abumiya T,Nakamura H,Shimbo D,Shichinohe H,Nakayama N,Kazumata K,Shimizu H,Houkin K

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:The present article describes a rare presentation of Type I neurofibromatosis (NFI) involving adjoining intercostal plexiform neurofibromas, as well as the novel use of thoracoscopy to guide surgical resection. This presentation highlights the manner in which NFI may affect selective regions of...

journal_title：Neurosurgery

authors： Salazar F,Machado A,Murthy S,Boulis NM

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Deep brain stimulation alleviates tremor of various origins. Several regions like the ventralis intermediate nucleus of thalamus, the caudal zona incerta, and the posterior subthalamic region are generally targeted. Previous work with fiber tractography has shown the involvement of the cerebello-thalamo-cort...

journal_title：Neurosurgery

authors： Coenen VA,Allert N,Paus S,Kronenbürger M,Urbach H,Mädler B

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Urinary disorders account for 10% of deaths in patients with complete spinal cord injury. Sacral anterior root stimulation (SARS) may be a valuable therapeutic option to restore complete and voluntary micturition (CVM), but questions on its cost-effectiveness remain. OBJECTIVE:To evaluate the cost-effective...

journal_title：Neurosurgery

authors： Bénard A,Verpillot E,Grandoulier AS,Perrouin-Verbe B,Chêne G,Vignes JR,French Study Group on SARS.

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Syringomyelia in association with the Dandy-Walker complex is rare and only 17 cases have been reported, mostly as autopsy findings or incidental reports in series for other conditions. We present a further case report and discuss the possible pathogenetic mechanisms of syrinx formation in the ...

journal_title：Neurosurgery

authors： Hammond CJ,Chitnavis B,Penny CC,Strong AJ

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Despite advances in surgical techniques in the management of the brain abscess, long-term antibiotics are as crucial to cure as the initial surgical procedure itself. This study was designed to evaluate the effect of adjuvant hyperbaric oxygen (HBO) therapy on the duration of antibiotic treatment. METHODS:Be...

journal_title：Neurosurgery

authors： Kutlay M,Colak A,Yildiz S,Demircan N,Akin ON

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:We sought to determine the risk of adverse outcome after contemporary surgical treatment of patients with unruptured intracranial aneurysms in the United States. Patient, surgeon, and hospital characteristics were tested as potential outcome predictors, with particular attention to the surgeon's and hospital'...

journal_title：Neurosurgery

authors： Barker FG 2nd,Amin-Hanjani S,Butler WE,Ogilvy CS,Carter BS

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Although previous evidence suggests that the cognitive effects of concussions are cumulative, the effect of time interval between repeat concussions is largely unknown. OBJECTIVE:To determine the effect of time interval between repeat concussions on the cognitive function of mice. METHODS:We used a weight-...

journal_title：Neurosurgery

authors： Meehan WP 3rd,Zhang J,Mannix R,Whalen MJ

更新日期：2012-10-01 00:00:00