Prediction of obliteration after gamma knife surgery for cerebral arteriovenous malformations.

Abstract:

OBJECTIVE:To define the factors of importance for the obliteration of cerebral arteriovenous malformations (AVMs), thus making a prediction of the probability for obliteration possible. METHODS:In 945 AVMs of a series of 1319 patients treated with the gamma knife during 1970 to 1990, the relationship between patient, AVMs, and treatment parameters on the one hand and the obliteration of the nidus on the other was analyzed. RESULTS:The obliteration rate increased both with increased minimum (lowest periphery) and average dose and decreased with increased AVM volume. The minimum dose to the AVMs was the decisive dose factor for the treatment result. The higher the minimum dose, the higher the chance for total obliteration. The curve illustrating this relation increased logarithmically to a value of 87%. A higher average dose shortened the latency to AVM obliteration. For the obliterated cases, the larger the malformation, the lower the minimum dose used. This prompted us to relate the obliteration rate to the product minimum dose (AVM volume)1/3 (K index). The obliteration rate increased linearly with the K index up to a value of approximately 27, and for higher K values, the obliteration rate had a constant value of approximately 80%. For the group of 273 cases treated with a minimum dose of at least 25 Gy, the obliteration rate at the study end point (defined as 2-yr latency) was 80% (95% confidence interval = 75-85%). If obliterations that occurred beyond the end point are included, the obliteration rate increased to 85% (81-89%). CONCLUSION:The probability of obliteration of AVMs after gamma knife surgery is related both to the lowest dose to the AVMs and the AVM volume, and it can be predicted using the K index.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Karlsson B,Lindquist C,Steiner L

doi

10.1097/00006123-199703000-00001

subject

Has Abstract

pub_date

1997-03-01 00:00:00

pages

425-30; discussion 430-1

issue

3

eissn

0148-396X

issn

1524-4040

journal_volume

40

pub_type

杂志文章
  • Meningioangiomatosis not associated with von Recklinghausen's disease.

    abstract::We report a rare case of meningioangiomatosis unassociated with von Recklinghausen's disease. The patient was a 30-year-old woman with a 25-year history of seizures. The lesion was confined to the right temporal cortex and consisted of a proliferation of angiomatous blood vessels and meningocytic cells. Her seizures h...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198705000-00023

    authors: Sakaki S,Nakagawa K,Nakamura K,Takeda S

    更新日期:1987-05-01 00:00:00

  • Neurological surgery at the University of Vienna.

    abstract::ANTON VON EISELSBERG was the first to resect a cerebral tumor at the First Surgical Clinic at the General Hospital in Vienna in 1904. He successfully removed a cerebral glioma, the first of no fewer than 15,000 tumors operated on at that hospital to date. von Eiselsberg and his successors, Egon Ranzi and Leopold Schön...

    journal_title:Neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.1097/00006123-199609000-00030

    authors: Koos WT,Day JD

    更新日期:1996-09-01 00:00:00

  • Computed tomography and cerebral blood flow correlations of mental changes in chronic subdural hematoma.

    abstract::To elucidate the pathophysiology of mental disturbances associated with chronic subdural hematoma, we performed quantitative and three-dimensional measurements of cerebral blood flow (CBF) on xenon-enhanced computed tomographic scans in 12 patients who had chronic subdural hematomas and manifested mental disturbances....

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199203000-00010

    authors: Tanaka A,Kimura M,Yoshinaga S,Ohkawa M

    更新日期:1992-03-01 00:00:00

  • Successful laser-assisted excision of a metastatic midbrain tumor.

    abstract::Metastatic lesions to the midbrain are rare. They are found in 1 to 3% of autopsy series of solitary brain metastases. The consensus of opinion in the current literature is that they are inoperable lesions and should be treated by radiation therapy alone. This is the first case report of a completely excised metastati...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198606000-00022

    authors: Tobler WD,Sawaya R,Tew JM Jr

    更新日期:1986-06-01 00:00:00

  • The effect of hypothermia and hyperthermia on photodynamic therapy of normal brain.

    abstract::The effect of whole body hyperthermia and hypothermia in conjunction with photodynamic therapy (PDT) was determined on normal rat brain. Hyperthermia animals (Group I, n = 18) were warmed until their core body temperature reached 40 degrees C, (brain temperature, 39.7 +/- 0.5 degree C) and maintained at 40 +/- 1 degre...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199501000-00018

    authors: Dereski MO,Madigan L,Chopp M

    更新日期:1995-01-01 00:00:00

  • Image guidance for transcranial Doppler ultrasonography.

    abstract:BACKGROUND:Transcranial Doppler (TCD) ultrasonography is an important tool for noninvasive detection and monitoring of vasospasm and other pathological conditions of the intracranial vessels. OBJECTIVE:To demonstrate that image-guided TCD allows rapid identification and blood-flow analysis of specific sections of the ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e31821553b2

    authors: Kantelhardt SR,Greke C,Keric N,Vollmer F,Thiemann I,Giese A

    更新日期:2011-06-01 00:00:00

  • Radiosurgery in the treatment of malignant gliomas: the University of Florida experience.

    abstract:OBJECTIVE:To review a single-institution's 12-year experience of treating malignant gliomas with linear accelerator-based radiosurgery. METHODS:One hundred patients were treated for malignant gliomas at the University of Florida between May 1, 1989, and June 12, 2002. Patient variables were entered into a radiosurgery...

    journal_title:Neurosurgery

    pub_type: 临床试验,杂志文章

    doi:10.1227/01.neu.0000170560.13251.99

    authors: Ulm AJ 3rd,Friedman WA,Bradshaw P,Foote KD,Bova FJ

    更新日期:2005-09-01 00:00:00

  • Symptomatic Adjacent Level Disease Requiring Surgery: Analysis of 10-Year Results From a Prospective, Randomized, Clinical Trial Comparing Cervical Disc Arthroplasty to Anterior Cervical Fusion.

    abstract:BACKGROUND:Ten-year follow-up data from the US Food and Drug Administration investigational device exemption trial comparing BRYAN® Cervical Disc (Medtronic, Dublin, Ireland) arthroplasty to anterior cervical discectomy and fusion (ACDF) demonstrated that disc arthroplasty maintained range of motion and improvements in...

    journal_title:Neurosurgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/neuros/nyy118

    authors: Ghobrial GM,Lavelle WF,Florman JE,Riew KD,Levi AD

    更新日期:2019-02-01 00:00:00

  • Immunohistochemical detection of intracranial vasa vasorum: a human autopsy study.

    abstract::The existence of intracranial vasa vasorum supplying the larger vessels of the circle of Willis has long been debated. Much of this debate results from contradictory findings of microanatomic studies in a variety of nonprimate species. Recently, however, a growing body of evidence seems to suggest that in certain path...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Connolly ES Jr,Huang J,Goldman JE,Holtzman RN

    更新日期:1996-04-01 00:00:00

  • The limited value of cytoreductive surgery in elderly patients with malignant gliomas.

    abstract::In this retrospective, consecutive series of 128 elderly patients (over 65 years of age) with histologically proven Grade 4 astrocytomas, 88 patients underwent stereotactic biopsy and 40 patients underwent stereotactic volumetric resection of the mass lesion defined by contrast enhancement on computed tomography. Ther...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Kelly PJ,Hunt C

    更新日期:1994-01-01 00:00:00

  • Magnetic source imaging combined with image-guided frameless stereotaxy: a new method in surgery around the motor strip.

    abstract:OBJECTIVE:In this study, information about the localization of the central sulcus obtained by magnetic source imaging (MSI) was intraoperatively translated to the brain, using frameless image-guided stereotaxy. In the past, the MSI results could be translated to the surgical space only by indirect methods (e.g., the co...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199709000-00023

    authors: Ganslandt O,Steinmeier R,Kober H,Vieth J,Kassubek J,Romstöck J,Strauss C,Fahlbusch R

    更新日期:1997-09-01 00:00:00

  • Corpus callosal changes associated with hydrocephalus: a report of two cases.

    abstract:OBJECTIVE AND IMPORTANCE:Focal or diffuse corpus callosal changes can occur in patients with active hydrocephalus who undergo shunting procedures. The neural compression caused by active hydrocephalus and the conditions that follow ventricular shunting may contribute to the development of these changes. CLINICAL PRESE...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199708000-00037

    authors: Suh DY,Gaskill-Shipley M,Nemann MW,Tureen RG,Warnick RE

    更新日期:1997-08-01 00:00:00

  • Angles between A1 and A2 segments of the anterior cerebral artery visualized by three-dimensional computed tomographic angiography and association of anterior communicating artery aneurysms.

    abstract:OBJECTIVE:The angle of arteries at bifurcations, as well as the blood flow, are factors of hemodynamic stress on the apical region, where aneurysms often develop. Using images obtained with three-dimensional computed tomographic angiography, we sought to determine the angles between the A1 and A2 segments of the anteri...

    journal_title:Neurosurgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006123-199907000-00021

    authors: Kasuya H,Shimizu T,Nakaya K,Sasahara A,Hori T,Takakura K

    更新日期:1999-07-01 00:00:00

  • Intra-arterial Cereport (RMP-7) and carboplatin: a dose escalation study for recurrent malignant gliomas.

    abstract:OBJECTIVE:Animal and human studies have shown increased delivery of radiolabeled compounds across the blood-brain-tumor barrier using intra-arterial (IA) Cereport (RMP-7; Alkermes Inc., Cambridge, MA) with a radiolabeled tracer. This present study assesses the safety, tolerance, and preliminary efficacy of the IA admin...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199902000-00015

    authors: Cloughesy TF,Black KL,Gobin YP,Farahani K,Nelson G,Villablanca P,Kabbinavar F,Viñeula F,Wortel CH

    更新日期:1999-02-01 00:00:00

  • The beaten copper cranium: a correlation between intracranial pressure, cranial radiographs, and computed tomographic scans in children with craniosynostosis.

    abstract:OBJECTIVE:The beaten copper appearance of the cranium, as well as other cranial radiographic and computed tomographic findings in children with craniosynostosis, is often interpreted by clinicians as evidence of elevated intracranial pressure (ICP). However, a correlation between radiological findings and ICP measureme...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199610000-00007

    authors: Tuite GF,Evanson J,Chong WK,Thompson DN,Harkness WF,Jones BM,Hayward RD

    更新日期:1996-10-01 00:00:00

  • Brain vascularization by transplanted omentum: a possible treatment of cerebral ischemia.

    abstract::The authors report their experience with experimental brain vascularization with the use of transplanted omentum majus. The possibility of treating cerebral ischemia with this method is discussed. ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-197711000-00006

    authors: Yonekawa Y,Yaşargil MG

    更新日期:1977-11-01 00:00:00

  • Strategies for Computed Tomography Radiation Dose Reduction in Pediatric Neuroimaging.

    abstract:BACKGROUND:Radiation exposure from diagnostic imaging is a significant concern, particularly in the care of pediatric patients. Computed tomography (CT) scanning is a significant source of radiation. OBJECTIVE:To demonstrate that diagnostic quality CT images can be obtained while minimizing the effective radiation dos...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0000000000000764

    authors: Albert GW,Glasier CM

    更新日期:2015-08-01 00:00:00

  • Magnetic microparticles for endovascular aneurysm treatment: in vitro and in vivo experimental results.

    abstract:OBJECTIVE:Endovascular treatment of intracranial aneurysms employing endosaccular coiling can be associated with aneurysm perforation, coil herniation or incomplete obliteration fueling the interest to investigate novel endovascular techniques. We aimed to test a novel embolization material in experimental aneurysms in...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e3182125eb0

    authors: Oechtering J,Kirkpatrick PJ,Ludolph AG,Hans FJ,Sellhaus B,Spiegelberg A,Krings T

    更新日期:2011-05-01 00:00:00

  • Stereotactic radiosurgery for cavernous malformations: Kjellberg's experience with proton beam therapy in 98 cases at the Harvard Cyclotron.

    abstract:OBJECTIVE:The lack of treatment options for surgically inaccessible cavernous malformations has made radiosurgery a possible alternative to conservative management. The few previous reports of radiosurgical efficacy have been limited by small numbers, short follow-up, or lack of attention to the full spectrum of end po...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199806000-00013

    authors: Amin-Hanjani S,Ogilvy CS,Candia GJ,Lyons S,Chapman PH

    更新日期:1998-06-01 00:00:00

  • The results, indications, and physiology of posteroventral pallidotomy for patients with Parkinson's disease.

    abstract::In the past, stereotactic surgical intervention for Parkinson's disease was considered indicated only in those patients with active motor manifestations that were refractory to pharmacological therapy, manifestations such as tremor, rigidity, dystonia, and dyskinesia. With the reintroduction and refinement of Leksell'...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199506000-00008

    authors: Iacono RP,Shima F,Lonser RR,Kuniyoshi S,Maeda G,Yamada S

    更新日期:1995-06-01 00:00:00

  • Psychosocial functioning at 1 month after head injury.

    abstract::The authors examined the psychosocial sequelae of head trauma at 1 month after injury in a group of 102 adult head-injured patients representing a broad range of severity of trauma. One hundred two control subjects selected from friends of the head-injured patients were used for comparison purposes. Outcome was determ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198404000-00001

    authors: McLean A Jr,Dikmen S,Temkin N,Wyler AR,Gale JL

    更新日期:1984-04-01 00:00:00

  • Saccular intracranial aneurysm disease: distribution of site, size, and age suggests different etiologies for aneurysm formation and rupture in 316 familial and 1454 sporadic eastern Finnish patients.

    abstract:OBJECTIVE:Finnish saccular intracranial aneurysm (sIA) disease associates to 2q33, 8q11, and 9p21 loci and links to 19q13, Xp22, and kallikrein cluster in sIA families. Detailed phenotyping of familial and sporadic sIA disease is required for fine mapping of the Finnish sIA disease. METHODS:Eastern Finland, which is p...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000367634.89384.4B

    authors: Huttunen T,von und zu Fraunberg M,Frösen J,Lehecka M,Tromp G,Helin K,Koivisto T,Rinne J,Ronkainen A,Hernesniemi J,Jääskeläinen JE

    更新日期:2010-04-01 00:00:00

  • George Chance and Frank Holdsworth: Understanding Spinal Instability and the Evolution of Modern Spine Injury Classification Systems.

    abstract::The concept of spinal cord injury has existed since the earliest human civilizations, with the earliest documented cases dating back to 3000 BC under the Egyptian Empire. Howevr, an understanding of this field developed slowly, with real advancements not emerging until the 20th century. Technological advancements incl...

    journal_title:Neurosurgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1093/neuros/nyaa081

    authors: Thakur JD,Wild E,Menger R,Hefner M,Adeeb N,Kalakoti P,Nanda A

    更新日期:2020-06-01 00:00:00

  • Variant intraneural vein-trigeminal nerve relationships: an observation during microvascular decompression surgery for trigeminal neuralgia.

    abstract:OBJECTIVE:Trigeminal neuralgia is often caused by compression, demyelination, and injury of the trigeminal nerve root entry zone by an adjacent artery and/or vein. Previously described variations of the nerve-vessel relationship note external nerve compression. We offer a detailed classification of intraneural vessels ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000351757.29658.C0

    authors: Helbig GM,Callahan JD,Cohen-Gadol AA

    更新日期:2009-11-01 00:00:00

  • The treatment of anaplastic oligodendrogliomas and mixed gliomas.

    abstract::We evaluated the treatment outcome of 17 patients with anaplastic oligodendroglioma and 17 patients with anaplastic mixed oligodendroglioma-astrocytoma. In the anaplastic oligodendroglioma group, eight patients were treated at the time of the initial admission with radiotherapy and adjuvant chemotherapy, and nine pati...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199303000-00005

    authors: Kyritsis AP,Yung WK,Bruner J,Gleason MJ,Levin VA

    更新日期:1993-03-01 00:00:00

  • Extracranial posterior inferior cerebellar artery aneurysm causing isolated intraventricular hemorrhage: a case report.

    abstract::The authors report the unusual case of an aneurysm arising on an extracranial loop of the left posterior inferior cerebellar artery (PICA). The computed tomographic scan showed an isolated hemorrhage in the lateral ventricles, and the lesion was recognized 1.5 cm below the foramen magnum at the level of the atlas. The...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198812000-00020

    authors: Ruelle A,Cavazzani P,Andrioli G

    更新日期:1988-12-01 00:00:00

  • Regional changes in central nervous system thyrotropin-releasing hormone after pentylenetetrazol-induced seizures in dogs.

    abstract::We have recently shown that seizures induce significant and sustained elevations of thyrotropin-releasing hormone (TRH) in specific extrahypothalamic rat brain regions associated with epileptic foci including amygdala, hippocampus, pyriform cortex, and anterior cortex. Seizures were induced in dogs to further study th...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199211000-00017

    authors: Shapiro S,Kubek M,Sanders S,Durbin S,Goodwin S,Javed T

    更新日期:1992-11-01 00:00:00

  • Embryonic central nervous system transplants mediate adult dorsal root regeneration into host spinal cord.

    abstract:OBJECTIVE:The aim of this study was to determine whether embryonic central nervous system transplants assisted cut dorsal root axons of adult rats to regenerate into the spinal cord. METHODS:Rats received transplants of embryonic spinal cord, hippocampus, or neocortex into dorsal quadrant cavities aspirated in the lum...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199910000-00024

    authors: Itoh Y,Mizoi K,Tessler A

    更新日期:1999-10-01 00:00:00

  • The Impact of Intracranial Tumor Proximity to White Matter Tracts on Morbidity and Mortality: A Retrospective Diffusion Tensor Imaging Study.

    abstract:Background:Using diffusion tensor imaging (DTI) in neurosurgical planning allows identification of white matter tracts and has been associated with a reduction in postoperative functional deficits. Objective:This study explores the relationship between the lesion-to-tract distance (LTD) and postoperative morbidity and...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyw040

    authors: Meyer EJ,Gaggl W,Gilloon B,Swan B,Greenstein M,Voss J,Hussain N,Holdsworth RL,Nair VA,Meyerand ME,Kuo JS,Baskaya MK,Field AS,Prabhakaran V

    更新日期:2017-02-01 00:00:00

  • Extended endoscopic transsphenoidal approach for tuberculum sellae meningiomas.

    abstract:OBJECTIVE:Tuberculum sellae meningiomas are classically removed through several different surgical transcranial approaches, including the pterional transsylvian route. Recently, the indications for the transsphenoidal technique, traditionally proposed only for the treatment of intrasellar lesions, have been extended to...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000333785.04435.2c

    authors: de Divitiis E,Cavallo LM,Esposito F,Stella L,Messina A

    更新日期:2008-06-01 00:00:00