Abstract：
OBJECTIVE:The aim of this study was to compare the efficacy of intravenous iron to oral iron in the treatment of anemia in pregnancy. METHODS:In this randomized open-label study, 90 women with hemoglobin levels between 8 and 10.5 g/dL and ferritin values less than 13 microg/L received either oral iron polymaltose complex (300 mg elemental iron per day) or intravenous iron sucrose. The iron sucrose dose was calculated from the following formula: weight before pregnancy (kg) x (110 g/L - actual hemoglobin [g/L]) x 0.24 + 500 mg. Treatment efficacy was assessed by measuring hemoglobin and ferritin on the 14th and 28th days and at delivery, and the hemoglobin on the first postpartum day. Adverse drug reactions, fetal weight, hospitalization time, and blood transfusions were also recorded. RESULTS:Hemoglobin values varied significantly with time between groups (interaction effect, P < .001). The change in hemoglobin from baseline was significantly higher in the intravenous group than the oral group at each measurement; the changes with respect to subsequent hemoglobin were significantly higher on the 14th (P = .004) and 28th (P = .031) days. Ferritin values were higher in patients receiving intravenous iron throughout pregnancy. No serious adverse drug reactions were observed. Fetal weight and hospitalization time were similar in the 2 groups. Blood transfusion was required for only one patient in the oral group. CONCLUSION:Intravenous iron treated iron-deficiency anemia of pregnancy and restored iron stores faster and more effectively than oral iron, with no serious adverse reactions.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Al RA,Unlubilgin E,Kandemir O,Yalvac S,Cakir L,Haberal Adoi
10.1097/01.AOG.0000185260.82466.b4subject
Has Abstractpub_date
2005-12-01 00:00:00pages
1335-40issue
6eissn
0029-7844issn
1873-233Xpii
106/6/1335journal_volume
106pub_type
杂志文章,随机对照试验abstract：BACKGROUND:Important clinical, social, and ethical questions are associated with the evaluation and use of surgical approaches aimed at correcting fetal anatomic abnormalities. In particular, the expansion of maternal-fetal surgery to ameliorate nonlethal fetal conditions has intensified the need to address issues abou...
journal_title：Obstetrics and gynecology
pub_type： 共识发展会议,杂志文章,评审
doi：10.1016/s0029-7844(01)01513-7
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND:The placement of a transabdominal cervical cerclage has been regarded as considerably more morbid than a transvaginal cerclage, in part due to the need for two laparotomies. We describe a technique for the laparoscopic placement and removal of a transabdominal cerclage. CASES:Two cases of women with insuffi...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(97)00655-8
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:To determine clinical characteristics of women with endometriosis-associated intraperitoneal cancers, to assess differences based on the relationship of the cancer to the endometriosis, and to assess factors associated with survival. METHODS:A search of medical records at The University of Texas M. D. Anders...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(02)02149-x
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy of a novel resorbable hydrogel barrier for preventing postoperative adhesions in animals. METHODS:A hydrogel barrier was formed in situ by photopolymerizing a solution of a macromolecular prepolymer in buffered saline using long-wavelength ultraviolet light. Two models in the rat were ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVE:To estimate the change in survival rates of women with ovarian cancer during the past 14 years. METHODS:Women diagnosed with epithelial, germ cell, sarcomas, and sex-cord stromal ovarian tumors were identified from the Surveillance Epidemiology and End Results Database. Demographic and clinicopathologic fact...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000231680.58221.a7
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVE:To evaluate whether there was a change in prevalence of human papillomavirus (HPV) in the United States correlated with the introduction of HPV vaccines in both vaccinated and unvaccinated women. METHODS:We performed a retrospective review of prevalence data for women aged 18-29 years living in the United St...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001760
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE:To identify characteristics associated with high inpatient daily opioid consumption after cesarean delivery. METHODS:This is a retrospective cohort study of all cesarean deliveries performed under neuraxial anesthesia with neuraxial morphine, at a single institution from January 1, 2015, to December 31, 2015...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003087
更新日期：2019-02-01 00:00:00
abstract：:This study reviews 27 patients with positive OCTs who were subsequently allowed a trial of directly monitored labor. Of these, 19 patients (70%) developed FHR signs of fetal distress and 8 (30%) tolerated labor without late decelerations. These patients were evaluated for signs of fetal reactivity (acceleration of the...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1977-12-01 00:00:00
abstract：:To determine whether planned anterior vaginotomy is a logical and safe means of avoiding a uterine scar with term abdominal delivery. I recorded the complications of the technique and whether vaginal birth after anterior vaginotomy occurred. Thirteen anterior vaginotomies were done when the vagina had advanced during ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(96)00209-8
更新日期：1996-09-01 00:00:00
abstract：:The diagnosis of a cervical ectopic pregnancy is often made intraoperatively in the presence of extensive hemorrhage during attempted evacuation. In some cases, hysterectomy has been the necessary treatment to control bleeding. We report two cases of cervical pregnancy detected by ultrasound. Before pregnancy terminat...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：OBJECTIVE:To determine if corticosteroid administration causes increased contractions or labor in high-order multiple gestations. METHODS:Medical records of all triplet and quadruplet pregnancies cared for by Phoenix Perinatal Associates from August 1988 to January 1992 were reviewed retrospectively. Twenty-one women ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(94)00355-H
更新日期：1995-02-01 00:00:00
abstract：OBJECTIVE:To determine the correlates of incontinence in middle-aged women and to test for an association between incontinence and depression. METHODS:This was a population-based cross-sectional study of 5701 women who were residents of the United States, aged 50-69 years, and participated in the third interview of th...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(02)02519-x
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To quantify the current perinatal consequences associated with intrapartum detection of meconium in the amniotic fluid (AF). METHODS:We compared retrospectively the outcomes in 8136 term singleton cephalic pregnancies with meconium and 34,573 similar pregnancies with clear AF. RESULTS:Virtually all measures...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:The results of 1000 consecutive unselected cases of induction of labor for medical or obstetric reasons using prostaglandin E2 suppositories are presented. The overall rate of failed induction resulting in a cesarean section in those patients with an unfavorable cervix has fallen from 42 to 2.5%. Only 27% of the entir...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1981-11-01 00:00:00
abstract：OBJECTIVE:To compare the effectiveness of orally administered nifedipine and intravenously administered labetalol for acute blood pressure control in hypertensive emergency of pregnancy. METHODS:In this double-blind, randomized, controlled trial, pregnant women with sustained increase in systolic blood pressure of 160...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1097/AOG.0b013e3182a9ea68
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:To use nationally representative data to produce prevalence estimates of combination estrogen-progestin therapy and estrogen-only therapy by covariates, and to evaluate differences between current use of short duration (less than 5 years) and current long-term use. METHODS:We analyzed data from female respon...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.obstetgynecol.2003.09.024
更新日期：2003-12-01 00:00:00
abstract：:This study compared peritoneal fluid volume, macrophage count, and macrophage concentration by diagnosis and cycle week of 426 patients undergoing laparoscopy. Patient diagnosis and cycle week had no significant interaction. Peritoneal fluid volume was dependent upon cycle week and diagnostic group, but macrophage cou...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1987-03-01 00:00:00
abstract：OBJECTIVE:To compare the incidence of hypertensive disorders of pregnancy among women living with human immunodeficiency virus (HIV) on combination antiretroviral therapy (ART) to women without HIV, and to evaluate the association of hypertensive disorders of pregnancy with ART regimens or timing of ART initiation. ME...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003584
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Doppler measurement of the fetal middle cerebral artery peak systolic velocity is a valuable tool in detecting the presence of fetal anemia in Rh-sensitized pregnancies. We present a case in which discordant left and right middle cerebral artery Dopplers complicated clinical management. CASE:An RhD-alloimmu...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000263463.09931.40
更新日期：2007-08-01 00:00:00
abstract：:Inappropriate milk-like secretion from the breasts is not infrequently encountered in patients. Usually these secretions have been identified as milk on the basis of their characteristic appearance, and only rarely has their identity as milk been proven by appropriate analysis. Since milk is chemically defined as a la...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1975-09-01 00:00:00
abstract：:The treatment of 224 patients with invasive squamous cell carcinoma of the vulva over a 20-year interval at the Mayo Clinic resulted in an overall survival rate of 75%, compared with 89% for age-matched controls. For patients with stage I disease, 5-year survival was 90%; for those with stages II, III, and IV, it was ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Blood coagulation and fibrinolytic inhibitors and the balance between and within the two systems were investigated in 26 normal pregnant women during pregnancy and the puerperium. The concentration of the coagulation inhibitors antithrombin and protein C remained within normal levels, whereas the mean level of free pr...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVE:To assess the rate of wound complications and evaluate the effectiveness of antibiotic prophylaxis in vulvar wide local excision procedures. METHODS:We performed a single-institution, retrospective cohort study of women undergoing vulvar surgery for premalignant lesions between January 2007 and January 2017....
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003185
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:To test the performance characteristics of a new DNA probe designed for the rapid identification of heavy colonization of the genital tract with group B streptococci. METHODS:Vaginal and combined vaginal-perianal samples were collected from 193 pregnant women and cultured on colistin-nalidixic acid agar plat...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/0029-7844(95)00199-2
更新日期：1995-10-01 00:00:00
abstract：:Mental health disorders in adolescence are a significant problem, relatively common, and amenable to treatment or intervention. Obstetrician-gynecologists who see adolescent patients are highly likely to see adolescents and young women who have one or more mental health disorders. Some of these disorders may interfere...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,实务指引
doi：10.1097/AOG.0000000000002153
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:Complex wound failures are a source of significant morbidity and mortality. They are costly and time consuming to treat, and may evolve into chronic, debilitating conditions. Vacuum-assisted closure is a novel wound healing technique applying subatmospheric pressure to wounds to expedite healing. CASES:We r...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(01)01752-5
更新日期：2002-03-01 00:00:00
abstract：:We studied 30 control women and 131 pill users to evaluate effects of birth control pills and clinical factors on hemostasis. When control patients were matched with an equal number of pill users, none of the direct markers of activated hemostasis (fibrinopeptide A, platelet factor 4, and beta thromboglobulin) were in...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
abstract：:To determine the validity of the Bonney test as a prognostic screening test for urinary incontinence, the urethral and urethrovesical functions were studied under resting and stressful conditions. The characteristic similarity of changes was evident in the functional profile length, closure pressure, and cough pressur...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-12-01 00:00:00
abstract：:Unsustainable health care costs combined with suboptimal patient outcomes have led health policy experts and payers to consider value-based payment or alternative payment models. Replacing fee-for-service reimbursement, these models link payment to value by rewarding efforts to enhance the quality of care at similar o...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000002753
更新日期：2018-08-01 00:00:00
abstract：:Cultures for Chlamydia trachomatis were obtained from 127 female adolescents (13-17 years of age) evaluated for reported sexual abuse. The rate of positive cultures for C trachomatis in this population was 14% (18 of 127). Neisseria gonorrhoeae was found in 12% (15 of 127) of these patients. All but two of the culture...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
