Hippocampal head atrophy after traumatic brain injury.

Abstract:

:Traumatic brain injury (TBI) causes hippocampal damage. The hippocampus can be macroscopically divided into the head, body and tail, which differ in terms of their sensitivity to excitability and also in terms of their cortical connections. We investigated whether damage also varies according to the hippocampal area involved, and studied the relationship of hippocampal reductions with memory performance. Twenty TBI patients and matched controls were examined. MRI measurements were performed separately for the hippocampal head, body and tail. Memory outcome was measured by Rey's auditory verbal learning test, Rey's complex figure test and a modified version of Warrington's facial recognition memory test. Group comparison showed that patients had bilateral hippocampal atrophy, mainly involving the hippocampal head. Moreover, TBI subjects showed verbal memory deficits which presented slight correlations with left hippocampal head atrophy.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Ariza M,Serra-Grabulosa JM,Junqué C,Ramírez B,Mataró M,Poca A,Bargalló N,Sahuquillo J

doi

10.1016/j.neuropsychologia.2005.11.007

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

1956-61

issue

10

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(05)00361-1

journal_volume

44

pub_type

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