Location and function of the human frontal eye-field: a selective review.

Abstract:

:The location and possible function of the human frontal eye-field (FEF) were evaluated by reviewing results of cerebral blood-flow (CBF) and lesion studies. A remarkable consistency was found regarding the rostro-caudal (Y: from -6 to 1 mm) and dorso-ventral (Z: from 44 to 51 mm) location of the FEF, as defined by the CBF method within a standardized stereotaxic system (the zero point for all X, Y and Z coordinates coinciding with the anterior commissure, Talairach and Tournoux [Co-planar Stereotactic Atlas of the Human Brain, Georg Thieme, Stuttgart, 1988]. In contrast, there was a marked variability along the mediolateral axis (X: from -24 to -40 mm for the left hemisphere and from 21 to 40 mm for the right hemisphere). The human FEF is thus located either in the vicinity of the precentral sulcus and/or in the depth of the caudalmost part of the superior frontal sulcus. In either case, this location challenges the commonly held view of the FEF being located in Broadmann's area 8. With regard to FEF function, the results of CBF studies failed to support a role for the FEF in the cognitive aspects of oculomotor control, such as the execution of anti-saccades. Blood-flow activation data are consistent in this respect with the results of lesion studies. It is proposed that future research on FEF function in human subjects may benefit from focusing on the visuomotor rather than the cognitive aspects of oculomotor control.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Paus T

doi

10.1016/0028-3932(95)00134-4

subject

Has Abstract

pub_date

1996-06-01 00:00:00

pages

475-83

issue

6

eissn

0028-3932

issn

1873-3514

pii

0028-3932(95)00134-4

journal_volume

34

pub_type

杂志文章,评审
  • Hemispheric asymmetry in event knowledge activation during incremental language comprehension: A visual half-field ERP study.

    abstract::During incremental language comprehension, the brain activates knowledge of described events, including knowledge elements that constitute semantic anomalies in their linguistic context. The present study investigates hemispheric asymmetries in this process, with the aim of advancing our understanding of the neural ba...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2016.02.004

    authors: Metusalem R,Kutas M,Urbach TP,Elman JL

    更新日期:2016-04-01 00:00:00

  • Enhanced articulatory speed in ambidexters.

    abstract::The possibility that incomplete speech lateralization might be related to reduced articulatory speed was investigated in two studies with normal, young adults. Contrary to expectations, speech was produced faster by ambidextrous subjects than by either strongly left- or strongly right-handed subjects under a number of...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(87)90144-8

    authors: Ponton CW

    更新日期:1987-01-01 00:00:00

  • Clinical impact of gait training enhanced with visual kinematic biofeedback: Patients with Parkinson's disease and patients stable post stroke.

    abstract::As the world's population ages, falls, physical inactivity, decreased attention and impairments in balance and gait arise as a consequence of decreased sensation, weakness, trauma and degenerative disease. Progressive balance and gait training can facilitate postural righting, safe ambulation and community participati...

    journal_title:Neuropsychologia

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.neuropsychologia.2015.04.020

    authors: Byl N,Zhang W,Coo S,Tomizuka M

    更新日期:2015-12-01 00:00:00

  • The role of prefrontal regions in the Stroop task.

    abstract::The Stroop is a classical paradigm that presumably involves the inhibition of automatic responses and is frequently used to assess the frontal lobe functions. We investigated the effect of discrete prefrontal lesions in a Stroop task. A sample of 32 patients with frontal lesions were matched with normal controls by se...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(94)00116-7

    authors: Vendrell P,Junqué C,Pujol J,Jurado MA,Molet J,Grafman J

    更新日期:1995-03-01 00:00:00

  • The neural correlates of change detection in the face perception network.

    abstract::A common view is that visual processing within the ventral visual stream is modulated by attention and awareness. We used fMRI adaptation to investigate whether activation in a network of brain regions involved with face recognition--namely the fusiform face area (FFA), occipital face area (OFA) and right superior tem...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2008.02.027

    authors: Large ME,Cavina-Pratesi C,Vilis T,Culham JC

    更新日期:2008-01-01 00:00:00

  • Emotion processing fails to modulate putative mirror neuron response to trained visuomotor associations.

    abstract::Recent neuroimaging studies have demonstrated that activation of the putative human mirror neuron system (MNS) can be elicited via visuomotor training. This is generally interpreted as supporting an associative learning account of the mirror neuron system (MNS) that argues against the ontogeny of the MNS to be an evol...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2016.01.033

    authors: Fitzgibbon BM,Kirkovski M,Fornito A,Paton B,Fitzgerald PB,Enticott PG

    更新日期:2016-04-01 00:00:00

  • Recall of remote episodic memories can appear deficient because of a gist-based retrieval orientation.

    abstract::Determining whether patients with amnesia can succeed in remembering their distant past has pivotal implications for theories of memory storage. However, various factors influence recall. We speculated that some patients with anterograde amnesia adopt a gist-based retrieval orientation for memories from all time perio...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2008.12.006

    authors: Rudoy JD,Weintraub S,Paller KA

    更新日期:2009-02-01 00:00:00

  • Double disconnection effects resulting from infiltrating tumors.

    abstract::Patients with left hemisphere lesions deep in parietal or parietal-occipital regions close to the lateral ventricles have been reported to have impaired performance on left ear speech stimuli in dichotic listening tests. This loss has been termed "paradoxical" because it presents at the ear ipsilateral to the lesion. ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(89)90134-6

    authors: Sidtis JJ,Sadler AE,Nass RD

    更新日期:1989-01-01 00:00:00

  • Attention and the readiness for action.

    abstract::The initiation of voluntary action is preceded by up to 2s of preparatory neural activity, originating in premotor and supplementary motor regions of the brain. The function of this extended period of pre-movement activity is unclear. Although recent studies have suggested that pre-movement activity is influenced by a...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2011.08.003

    authors: Baker KS,Mattingley JB,Chambers CD,Cunnington R

    更新日期:2011-10-01 00:00:00

  • Sex and individual differences in induced and evoked EEG measures of action observation.

    abstract::We used two established methods for analysing the EEG response of the neurotypical adult human brain to examine the execution and observation of simple motor actions. In one, execution or observation of a button-press in response to a tone caused a decrease in the power at 8-13 Hz ("mu") frequencies. In the other, the...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2010.03.004

    authors: Silas J,Levy JP,Nielsen MK,Slade L,Holmes A

    更新日期:2010-07-01 00:00:00

  • Deficits of knowledge versus executive control in semantic cognition: insights from cued naming.

    abstract::Deficits of semantic cognition in semantic dementia and in aphasia consequent on CVA (stroke) are qualitatively different. Patients with semantic dementia are characterised by progressive degradation of central semantic representations, whereas multimodal semantic deficits in stroke aphasia reflect impairment of execu...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2007.09.007

    authors: Jefferies E,Patterson K,Ralph MA

    更新日期:2008-01-31 00:00:00

  • Word fluency in relation to severity of closed head injury, associated frontal brain lesions, and age at injury in children.

    abstract::Effects of closed head injury (CHI) severity, focal brain lesions, and age at injury on word fluency (WF) were studied longitudinally in 122 children (78 severe, 44 mild); 112 CHI patients (68 severe, 44 mild CHI) and 104 uninjured normal controls participated in a cross-sectional study. WF was measured by asking the ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(00)00111-1

    authors: Levin HS,Song J,Ewing-Cobbs L,Chapman SB,Mendelsohn D

    更新日期:2001-01-01 00:00:00

  • Theory of mind after traumatic brain injury.

    abstract::This study investigated whether people with severe traumatic brain injury (TBI) demonstrate a specific impairment on tasks requiring them to make inferences about others' mental states (theory of mind tasks). Participants with severe TBI were compared to a healthy group on verbal first-order and second-order theory of...

    journal_title:Neuropsychologia

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.neuropsychologia.2004.04.027

    authors: Bibby H,McDonald S

    更新日期:2005-01-01 00:00:00

  • Noun and knowledge retrieval for biological and non-biological entities following right occipitotemporal lesions.

    abstract::We investigated the critical contribution of right ventral occipitotemporal cortex to knowledge of visual and functional-associative attributes of biological and non-biological entities and how this relates to category-specificity during confrontation naming. In a consecutive series of 7 patients with lesions confined...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2014.07.021

    authors: Bruffaerts R,De Weer AS,De Grauwe S,Thys M,Dries E,Thijs V,Sunaert S,Vandenbulcke M,De Deyne S,Storms G,Vandenberghe R

    更新日期:2014-09-01 00:00:00

  • Further evidence for asymmetry of point localization in normals and unilateral brain damaged patients.

    abstract::The properties of errors made by normals and unilateral brain damaged patients in localizing points in each half of a plane have been further investigated. A lesion of either hemisphere affects specifically the performance in the left half of the plane, where controls attain the highest degree of constancy. Considerat...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(83)90028-3

    authors: Tartaglione A,Cocito L,Bino G,Pizio N,Favale E

    更新日期:1983-01-01 00:00:00

  • Heterotopagnosia: When I point at parts of your body.

    abstract::Heterotopagnosia is the acquired inability of brain-lesioned patients to point at someone else's body parts when prompted. The cognitive basis of this disorder is unclear. It might result from a biological function deficit critical for communication in human beings; alternatively, it could result from the disruption o...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2009.02.016

    authors: Cleret de Langavant L,Trinkler I,Cesaro P,Bachoud-Lévi AC

    更新日期:2009-06-01 00:00:00

  • An fMRI study of the Trail Making Test.

    abstract::This study investigated the cerebral correlates of the Trail Making Test (TMT), used commonly as a measure of frontal lobe function. Such work sheds additional light on the known shortcomings of the TMT as a localizing instrument, as indicated, for example, by studies of patients with focal brain lesions. Functional m...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2005.03.013

    authors: Zakzanis KK,Mraz R,Graham SJ

    更新日期:2005-01-01 00:00:00

  • More than skin deep: body representation beyond primary somatosensory cortex.

    abstract::The neural circuits underlying initial sensory processing of somatic information are relatively well understood. In contrast, the processes that go beyond primary somatosensation to create more abstract representations related to the body are less clear. In this review, we focus on two classes of higher-order processi...

    journal_title:Neuropsychologia

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuropsychologia.2009.08.022

    authors: Longo MR,Azañón E,Haggard P

    更新日期:2010-02-01 00:00:00

  • Affective prosody: what do comprehension errors tell us about hemispheric lateralization of emotions, sex and aging effects, and the role of cognitive appraisal.

    abstract::The Aprosodia Battery was developed to distinguish different patterns of affective-prosodic deficits in patients with left versus right brain damage by using affective utterances with incrementally reduced verbal-articulatory demands. It has also been used to assess affective-prosodic performance in various clinical g...

    journal_title:Neuropsychologia

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.neuropsychologia.2010.12.024

    authors: Ross ED,Monnot M

    更新日期:2011-04-01 00:00:00

  • Deviant neurophysiological responses to phonological regularities in speech in dyslexic children.

    abstract::Developmental dyslexia is strongly associated with a phonological deficit. Yet, implicit phonological processing (in)capacities in dyslexia remain relatively unexplored. Here we use a neurophysiological response sensitive to experience-dependent auditory memory traces, the mismatch negativity (MMN), to investigate imp...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2006.11.009

    authors: Bonte ML,Poelmans H,Blomert L

    更新日期:2007-04-08 00:00:00

  • Tracking lexical consolidation with ERPs: Lexical and semantic-priming effects on N400 and LPC responses to newly-learned words.

    abstract::Novel words can be recalled immediately and after little exposure, but require a post-learning consolidation period to show word-like behaviour such as lexical competition. This pattern is thought to reflect a qualitative shift from episodic to lexical representations. However, several studies have reported immediate ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2015.10.020

    authors: Bakker I,Takashima A,van Hell JG,Janzen G,McQueen JM

    更新日期:2015-12-01 00:00:00

  • The role of configural information in facial emotion recognition in schizophrenia.

    abstract::The schizophrenia deficit in facial emotion recognition could be accounted for by a deficit in processing the configural information of the face. The present experiment was designed to further test this hypothesis by studying the face-inversion effect in a facial emotion recognition task. The ability of 26 schizophren...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2006.04.008

    authors: Chambon V,Baudouin JY,Franck N

    更新日期:2006-01-01 00:00:00

  • Top-down attention modulation on the perception of others' vocal pain: An event-related potential study.

    abstract::Pain is typically expressed through various sensory (e.g., visual and auditory) modalities: the human voice conveys information about social and affective communication. While the empathic responses to others' pain in the visual modality are modulated by top-down attention constraints, it remains unclear whether empat...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2019.107177

    authors: Meng J,Shen L,Li Z,Peng W

    更新日期:2019-10-01 00:00:00

  • Activity and effective connectivity of parietal and occipital cortical regions during haptic shape perception.

    abstract::It is now widely accepted that visual cortical areas are active during normal tactile perception, but the underlying mechanisms are still not clear. The goal of the present study was to use functional magnetic resonance imaging (fMRI) to investigate the activity and effective connectivity of parietal and occipital cor...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2006.03.003

    authors: Peltier S,Stilla R,Mariola E,LaConte S,Hu X,Sathian K

    更新日期:2007-02-01 00:00:00

  • Attention and sensation in functional motor disorder.

    abstract::Functional motor disorder (FMD), also called psychogenic motor disorder or conversion disorder, describes impairments of motor function where there is no evidence of organic disease. The diagnosis is usually confirmed by positive clinical signs, such as Hoover's sign, in which normal power returns when attention is di...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2017.09.031

    authors: McIntosh RD,McWhirter L,Ludwig L,Carson A,Stone J

    更新日期:2017-11-01 00:00:00

  • Hemispheric asymmetries in bilinguals: tongue similarity affects lateralization of second language.

    abstract::It is known that the left hemisphere of the human brain is critical in understanding and producing spoken language, but it remains a topic of great interest determining the cerebral lateralization of multiple languages. The aim of this study is to examine the effects of similarity between languages on hemispheric asym...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2013.03.016

    authors: D'Anselmo A,Reiterer S,Zuccarini F,Tommasi L,Brancucci A

    更新日期:2013-06-01 00:00:00

  • Clarifying the relationship between trait empathy and action-based resonance indexed by EEG mu-rhythm suppression.

    abstract::Sensorimotor resonance, the vicarious activation of the sensory motor system during observation of another's actions, is thought to contribute to important social functions including empathy. Previous research has shown that sensorimotor resonance, as measured by suppression of the electrophysiological (EEG) mu rhythm...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2019.107172

    authors: DiGirolamo MA,Simon JC,Hubley KM,Kopulsky A,Gutsell JN

    更新日期:2019-10-01 00:00:00

  • The role of the left mesial frontal cortex in fluent speech: evidence from a case of left supplementary motor area hemorrhage.

    abstract::This study reports on a woman who suffered left anterior cerebral artery hemorrhage with a focal lesion undercutting the left supplementary motor area. After almost complete recovery of language the patient was left with dysfluent, halting speech. In a series of four experiments we examined the major factors influenci...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(97)00040-7

    authors: Ziegler W,Kilian B,Deger K

    更新日期:1997-09-01 00:00:00

  • Lack of interlimb transfer following visuomotor adaptation in a person with congenital mirror movements.

    abstract::Congenital mirror movements (CMMs) have been traditionally thought to occur due to the corticospinal tracts that project abnormally to both sides of the body. More recently, it has been suggested that both brain hemispheres are activated during intended unilateral movements due to deficient transcallosal inhibition, l...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2019.107265

    authors: Bao S,Morgan AM,Lei Y,Wang J

    更新日期:2020-01-01 00:00:00

  • Faces are special but not too special: spared face recognition in amnesia is based on familiarity.

    abstract::Most current theories of human memory are material-general in the sense that they assume that the medial temporal lobe (MTL) is important for retrieving the details of prior events, regardless of the specific type of materials. Recent studies of amnesia have challenged the material-general assumption by suggesting tha...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2010.09.005

    authors: Aly M,Knight RT,Yonelinas AP

    更新日期:2010-11-01 00:00:00