Abstract:
OBJECTIVES:To review the development of targeted therapies and the biology of relevant therapeutic targets. To analyze the relevance of targeted agents as part of current clinical practice. DATA SOURCES:Research articles. CONCLUSION:Several targeted agents are now available for clinical use. Their mechanisms of action are more specific against tumor cells than traditional cytotoxics. Monotherapy regimens based on targeted agents tend to be better tolerated than chemotherapy, and most combination regimens with targeted agents have proven feasible. Their availability has greatly expanded cancer treatment options, especially for chemorefractory patients. IMPLICATIONS FOR NURSING PRACTICE:Nurses involved in the care of patients with cancer can benefit from an increased understanding of targeted therapies, including their mechanisms of action, their efficacy profile, as well as prophylaxis and management of adverse events and administration procedures.
journal_name
Semin Oncol Nursjournal_title
Seminars in oncology nursingauthors
Kay Pdoi
10.1016/j.soncn.2006.01.009subject
Has Abstractpub_date
2006-02-01 00:00:00pages
1-4issue
1 Suppl 1eissn
0749-2081issn
1878-3449pii
S0749-2081(06)00032-5journal_volume
22pub_type
杂志文章,评审abstract:OBJECTIVES:To discuss unique issues related to cancer predisposition genetic testing and informed consent. DATA SOURCES:Published professional articles, review articles, research articles, clinical practice, position statements, websites, and textbooks. CONCLUSIONS:The discovery of germline mutations that confer a pr...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(99)80068-0
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVES:To define and distinguish informed decision-making (IDM) from shared decision-making (SDM) and review the evidence for technology-based interventions designed to facilitate informed decisions about cancer screening and treatment. DATA SOURCES:Peer-reviewed research articles from Medline and other data sourc...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/j.soncn.2011.04.004
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVES:To review the current evidence on the impact of minimally invasive, robotic-assisted cancer surgery (thoracic, gastrointestinal, gynecologic, genitourinary) on surgical outcomes and quality of life. DATA SOURCES:Journal articles, research reports, state of the science papers, and clinical guidelines. CONCL...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2016.11.003
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To provide a review of cancer vaccines, how they work, and the current state of the science underlying these treatments. DATA SOURCES:Research studies, review articles, book chapters, personal communications. CONCLUSION:Vaccines have been studied in a variety of malignancies; however, melanoma has provided ...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(03)00048-2
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVES:To review the current knowledge on living with bodily changes in hormone refractory prostate cancer (HRPC), treatment options, and common symptoms, and suggestions for improving our understanding of the experience of HRPC. DATA SOURCE:Existing literature, research, and clinical experience. CONCLUSION:Allev...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2011.07.009
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVES:To provide a review of the nursing committees in both the Children's Cancer Group and the Pediatric Oncology Group and discuss intergroup nursing research collaboration in preparation for the merger of these cooperative clinical trials groups. DATA SOURCES:Review articles, reports, and newsletters from coop...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1053/sonu.2000.16576
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To review the epidemiology, pathology, clinical features, prognostic factors, and treatment approaches of patients with AIDS-related lymphoma. DATA SOURCES:Research studies and review articles. CONCLUSION:Aggressive B-cell lymphoma has become one of the more common of the initial AIDS-defining illnesses in ...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2006.01.004
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVES:To identify treatment-related toxicities that are either more frequent or more severe in the adolescent and young adult (AYA) oncology population. To explore differences in drug pharmacology and patient physiology that contribute to toxicities in the AYA population and to describe the impact of treatment-rel...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2015.05.003
更新日期:2015-08-01 00:00:00
abstract::This article proposes that the nurse understand culture ideationally in terms of models of reality. A distinction is made between cultural and individual models, and between lay persons' models of sickness and practitioners' models. These are described and discussed in relation to the meanings of cancer. A role for th...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/s0749-2081(95)80036-0
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVES:To explore the role of the arts in spirituality and spiritual care and the importance of the arts and creativity in health care settings, particularly where individuals are confronting life-threatening illnesses. DATA SOURCES:Professional and lay journals/magazines, and personal experience with oncology and...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/s0749-2081(97)80018-6
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVES:Enrollment barriers and multidisciplinary approaches to increase cancer trials participation are presented. Recruitment barriers, research in Maryland, and a Best Practice for cancer trials are discussed. DATA SOURCES:Journal and research articles, web sites. CONCLUSION:Clinical trials have produced preven...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/j.soncn.2008.08.006
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:To provide an overview of the history of electronic health policy and identify significant laws that influence health informatics. DATA SOURCES:US Department of Health and Human Services. CONCLUSION:The development of health information technology has influenced the process for delivering health care. Publ...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2018.03.010
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVES:To describe pediatric palliative care (PPC) in pediatric oncology, the importance of PPC for pediatric oncology patients, disparities within pediatric palliative oncology, innovative strategies for improving PPC access in underserved populations, and implications for oncology nursing practice. DATA SOURCES:...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2018.06.010
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVES:To discuss current long-term follow-up management, the need for a long-term database, and creative strategies for follow-up care for cancer survivors. DATA SOURCES:Published articles, position statements, and personal experience. CONCLUSIONS:As the number of long-term cancer survivors increases, there need...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1053/sonu.2001.27921
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVES:To provide a review of the major and minor risk factors for the development of breast cancer and the options for prevention and treatment in women at high risk for breast cancer. DATA SOURCES:Clinical and research articles and textbooks. CONCLUSIONS:Breast cancer is the leading cancer found in women in the...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1053/sonc.2000.8110
更新日期:2000-08-01 00:00:00
abstract:OBJECTIVES:To provide a review of the pathophysiology and corresponding signs and symptoms of tumor lysis syndrome (TLS); to review clinical and laboratory monitoring parameters. DATA SOURCES:Primary and tertiary literature and clinical experience. CONCLUSIONS:An understanding of the pathophysiology of TLS, meticulou...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(02)80100-0
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVE:To review assessment and management approaches for chemotherapy-induced peripheral neuropathy-related physical function deficits. DATA SOURCES:Peer-reviewed articles from PubMed, Ovid MEDLINE, CINAHL PsycINFO, SPORTDiscus, Scopus, and key studies' reference lists. CONCLUSION:Brief clinical tests (eg, gait, ...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2019.150983
更新日期:2020-02-01 00:00:00
abstract::Clinical trials are vital for the development of state-of-the-art cancer prevention and treatment. A goal for trial recruitment should be to have a representative sample of the total population by gender, race, culture, ethnicity, and socioeconomic status as appropriate. Increased sensitivity to the unique barriers an...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(05)80066-x
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVES:To examine patterns and trends in lung cancer and the risk factors associated with development of this disease. DATA SOURCES:Epidemiologic studies, research studies, review articles, and government reports pertaining to epidemiology of lung cancer. CONCLUSION:Epidemiological evidence documents that most lu...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(96)80023-4
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVES:To review the evidence for considering fatigue, depression, and insomnia as a symptom cluster in cancer. DATA SOURCES:Empirical studies, clinical articles, and review articles. CONCLUSION:The single- and multi-symptom measurement approaches are of limited usefulness in distinguishing fatigue, depression, a...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/j.soncn.2007.01.004
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVES:To identify the most common gastrointestinal toxicities and laboratory abnormalities associated with targeted therapies, as well as the assessment and management necessary to minimize adverse events related to these side effects. DATA SOURCES:Peer-reviewed articles and national guidelines for oncology pract...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/j.soncn.2014.05.006
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:To review the etiology, epidemiology, classification, diagnosis, staging, prognosis, treatment, and nursing implications of non-Hodgkin's lymphoma. DATA SOURCES:Research studies, review articles, and book chapters pertaining to non-Hodgkin's lymphoma. CONCLUSIONS:Non-Hodgkins's lymphomas are a heterogeneou...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/s0749-2081(98)80005-3
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVES:To identify key educational and scientific tasks for the incorporation of complementary and alternative medical therapies (CAM) into conventional health care. DATA SOURCES:Journal articles, government and special health report, book chapters, and curriculum guidebooks. CONCLUSION:Nursing education programs...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2005.04.011
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVES:To provide an overview of research and practice related to the physical well-being of oncology caregivers. DATA SOURCES:Literature retrieved through the PubMed and CINAHL databases. CONCLUSION:Caregivers play an important role in supporting people with cancer at every stage of the illness trajectory. Becau...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/j.soncn.2012.09.005
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVES:To review the development of advocacy and its influence on health policy from the perspective of AIDS, the American Cancer Society, the Cancer Leadership Council, and the Patient Advocacy Foundation. DATA SOURCES:Published articles, news articles, books and personal experience. CONCLUSIONS:Advocacy on beha...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1053/sonu.2002.35937
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVES:To review the progress in the management of ovarian cancer in the last decade and future directions. DATA SOURCES:Research studies, review articles, and abstracts. CONCLUSIONS:There is an increased understanding of ovarian cancer biology, the genetic basis for hereditary ovarian cancer, staging and the rol...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1053/sonu.2002.34078
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVES:To synthesize state of the knowledge collected in this volume and propose future directions for lesbian, gay, bisexual and transgender (LGBT) cancer practice, education, research, and advocacy. DATA SOURCES:Current and extant literature. CONCLUSION:Health care disparities that are known but not yet fully e...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2017.12.007
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To discuss the implications of electronic systems and regulations regarding the use of electronic systems implemented during the conduct of a clinical trial and identify the impact of such platforms on oncology nurses' responsible for providing care to the research participant. DATA SOURCES:Peer-reviewed jou...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2020.151005
更新日期:2020-04-01 00:00:00
abstract::The diagnosis and initial treatment of a parent for cancer is a highly stressful process that generates a variety of concerns for adult children. This study describes the initial effect of a parent's cancer on adult children. Adult children's concerns about role and relationship issues emerged as major themes in the c...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章
doi:10.1016/s0749-2081(05)80105-6
更新日期:1993-05-01 00:00:00
abstract:OBJECTIVES:To discuss the advantages of using intensity modulated radiation therapy (IMRT), planning and delivery systems, clinical applications in specific cancers, considerations in the use of this technology, as well as implications for nursing practice. DATA SOURCES:Journal articles, journal reviews, and book chap...
journal_title:Seminars in oncology nursing
pub_type: 杂志文章,评审
doi:10.1016/j.soncn.2006.07.007
更新日期:2006-11-01 00:00:00