Abstract：
:Serum corticosteroid-binding globulin (CBG) concentrations in blood respond to endogenous or exogenous estrogens in a dose-response manner and serve as a biologic assay for estrogens. Because endometrial carcinoma is associated with unopposed or excessive estrogen stimulation, the CBG binding capacity of sera of patients with endometrial cancer was compared to that of normal premenopausal and postmenopausal women. The mean +/- SEM values for CBG concentrations in patients with endometrial cancer (28.3 +/- 1.3 mg/L) were significantly greater than CBG concentrations in premenopausal women (21.4 +/- 0.9 mg/L, p less than 0.001), but not significantly different from those of normal postmenopausal women (26.7 +/- 1.2 mg/L). Patients with polycystic ovarian disease, a risk factor for endometrial carcinoma, also had CBG concentrations significantly greater than those of normal premenopausal women (27.9 +/- 1.8 mg/L, p less than 0.01). CBG levels decline with age (r = -0.6474, p less than 0.05) but are unaffected by body weight or percent ideal body weight. These results indicate that CBG can distinguish categories of patients at risk for endometrial carcinoma, but it is not an effective biochemical marker for patients in these high-risk groups who have or will develop endometrial carcinoma.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Wilson EA,Jawad MJ,Donaldson ESdoi
10.1016/0002-9378(81)90480-4subject
Has Abstractpub_date
1981-03-15 00:00:00pages
661-4issue
6eissn
0002-9378issn
1097-6868pii
0002-9378(81)90480-4journal_volume
139pub_type
杂志文章abstract：OBJECTIVE:Our purpose was to investigate levels of fetal fibronectin in maternal plasma, amniotic fluid, and umbilical cord plasma from patients with severe preeclampsia. STUDY DESIGN:The study group comprised 20 patients with severe preeclampsia (group A). An antepartum comparison group was composed of 20 healthy pat...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(95)90587-1
更新日期：1995-02-01 00:00:00
abstract：OBJECTIVES:Our objective in this study was to assess the basic mechanical properties of umbilical and chorionic vessels of placentas delivered after both normal and preeclamptic pregnancies. STUDY DESIGN:Placentas were selected when the parturient women were admitted to the delivery room. Normal pregnancy (n = 17) was...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(11)90795-9
更新日期：1993-05-01 00:00:00
abstract：:Laparoscopic pelvic lymphadenectomy was performed in 39 patients. An incision of the peritoneum between the round and infundibulo-pelvic ligament on each side gave access to the retroperitoneal space. Subsequently, laparoscopic surgery allowed precise dissection of external and internal iliac vessels, umbilical artery...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(11)80025-6
更新日期：1991-02-01 00:00:00
abstract：:The bioavailability of a single dose of intranasal nafarelin was evaluated in 15 healthy female volunteers. Each subject received a 400 micrograms intranasal and a 25 micrograms intravenous dose of nafarelin separated by at least 7 days. Blood samples were obtained frequently after each dose for determination of nafar...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(92)91710-r
更新日期：1992-02-01 00:00:00
abstract：:A letter is written in response to a report by Drs. Beric, Kupresanin, and Hulka (Am. J, Obslet Gynecol. 114: 273, 1972) which stated that the Karman catheter is not suitable for terminating pregnancies beyond Week 6 of pregnancy. The use of a Karman catheter in terminating pregnancies of 7-10 weeks resulted in 47% t...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(73)91070-3
更新日期：1973-05-15 00:00:00
abstract：:Observational studies demonstrate that women with severe periodontitis have a higher risk of adverse pregnancy outcomes like preterm birth and low birthweight. Standard treatment for periodontitis in the form of scaling and root planing during the second trimester failed to reduce the risk of preterm or low birthweigh...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.ajog.2019.04.029
更新日期：2019-11-01 00:00:00
abstract：:Analysis of uncultured chorionic villus material from a woman at risk of fetus with sulfite oxidase deficiency revealed a deficiency of sulfite oxidase. This was confirmed on termination of the pregnancy. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(90)90691-y
更新日期：1990-10-01 00:00:00
abstract：:Production of a biologically active prolactin by human decidual tissue and its influence on the permeability of amniochorion to water suggests a functional relationship between the polypeptide and fetal membrane metabolism. Under in vitro circumstances, we used ovine prolactin and the Ussing chamber technique to deter...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(85)90375-8
更新日期：1985-04-15 00:00:00
abstract：:We report an asymptomatic 23-year-old female patient who was diagnosed to have a transmigrated intrauterine device (IUD) during a routine gynecological examination. After the IUD had been located within the colonic wall by further investigation, the IUD was successfully extracted via transanal route by colonoscopic in...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2010.11.037
更新日期：2011-03-01 00:00:00
abstract：:The concentrations of certain steroids in arterial and ovarian venous blood were measured in 42 postmenopausal women undergoing hysterectomy for uterine disease. A concentration gradient across the ovary was found for testosterone in 21 women, for androstenedione in 16, for estradiol in 15, for estrone in 8, and for d...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(80)90287-2
更新日期：1980-11-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the risk of cumulative cervical intraepithelial neoplasia (CIN) grade 2 or 3 according to initial colposcopy and directed biopsy results among women with low-grade squamous intraepithelial lesions (LSIL) or human papillomavirus (HPV) DNA positive atypical squamous ce...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2003.461
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:The objective of the study was to determine the amniotic fluid soluble intercellular adhesion molecule-1 concentrations in women with preterm labor in relation to intra-amniotic infection. STUDY DESIGN:Amniotic fluids from 125 women with preterm labor (78 with preterm delivery and 47 with term deliveries) we...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2006.05.020
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:Subcuticular skin closure with suture after cesarean has been shown to result in lower rates of wound complications than with staple closure. However, the optimal choice of suture material for subcuticular skin closure is unclear. Vicryl (a braided multifilament synthetic suture; Ethicon, Somerville, NJ) and...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajog.2016.05.012
更新日期：2016-10-01 00:00:00
abstract：:Changes in the drinking and smoking habits of pregnant women in Seattle, Washington, were examined in the 6-year period that followed the first American announcement of the fetal alcohol syndrome. Between 1974/1975 and 1980/1981, the number of women who reported any alcohol use around the time of the first prenatal vi...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(83)90579-3
更新日期：1983-03-15 00:00:00
abstract：OBJECTIVE:This study was undertaken to determine whether maternal posture (left lateral recumbent vs semi-Fowler position) had any effect on nonstress test results when the test was performed for a shortened period (10 minutes). STUDY DESIGN:In this randomized clinical trial of 108 patients with singleton pregnancies ...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1067/mob.2000.105443
更新日期：2000-05-01 00:00:00
abstract：:Because of various prenatal diagnoses, 606 fetal blood samplings were carried out in 562 pregnancies from the gestational week 17 to 38 with use of a 20-gauge needle guided by ultrasound. The procedure was performed on outpatients under local anesthesia and without medication before or after the procedure. Pure fetal ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(85)80254-4
更新日期：1985-11-15 00:00:00
abstract：OBJECTIVE:The purpose of this study was to examine the presence and frequency of antegrade late diastolic arterial blood flow (ALDAF) in the fetus and to determine its contribution to cardiac output. STUDY DESIGN:We evaluated the presence of ALDAF in 457 fetal and 21 postnatal echocardiograms. The timing of ALDAF to t...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2013.02.053
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:During early pregnancy fetal cytotrophoblast cells invade the uterus and penetrate the basement membrane, a property that is characteristic of malignant cells. However, unlike tumor invasion, trophoblast invasion of the uterus is under strict control. This control limits invasion, so that it primarily remains...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(94)90107-4
更新日期：1994-09-01 00:00:00
abstract：:Oral contraceptives (OCs) raise the plasma levels of some clotting factors, especially factor VII. Until recently, however, there has been no evidence for a relationship between high levels of clotting factor and the onset of clinically manifest vascular disease. It has not been established, on a preliminary basis, th...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(16)32484-x
更新日期：1982-03-15 00:00:00
abstract：:Reanalysis of data on the ovulation method of natural family planning collected by the World Health Organization yields the following conclusions. The method is effective during perfect (correct and consistent) use, with a first-year probability of failure of 3.4%. However, it is extremely unforgiving of imperfect use...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(11)90581-x
更新日期：1991-12-01 00:00:00
abstract：:The term microinvasive carcinoma is inappropriate when applied to all vulvar cancers less than or equal to 5 mm thick because approximately 50% of vulvar carcinomas are no thicker than 5 mm and 20% of those superficial tumors metastasize to the lymph nodes. The significant predictors of groin node metastases in patien...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(87)90132-3
更新日期：1987-05-01 00:00:00
abstract：OBJECTIVE:The electrophysiologic properties of gap junctions between human myometrial smooth muscle cells were studied. STUDY DESIGN:Double whole-cell patch clamp recordings were made on pairs of cells from primary cultures of myometrial cells from women undergoing cesarean section. Macroscopic gap junction currents w...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(98)70443-0
更新日期：1998-03-01 00:00:00
abstract：:Endometriosis, menorrhagia, chronic pelvic pain, and polycystic ovary syndrome are major sources of psychologic morbidity and can negatively affect quality of life. Although comparative studies have been published on the measurement of health-related quality of life for gynecologic malignancies, a similar review for t...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1067/mob.2002.124940
更新日期：2002-08-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to evaluate delivery outcome after maternal use of oral decongestants. STUDY DESIGN:We identified 2474 women who had reported the use of oral decongestants (mainly phenylpropanolamine) during early pregnancy and 1771 women who used prescription oral decongestants later in pregna...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2005.06.087
更新日期：2006-02-01 00:00:00
abstract：:A critical review of selected studies of breech delivery is presented with special attention to the statistical analysis of outcome for low birth weight and term breech delivery. Analysis of the data fails to support the routine use of cesarean birth for all cases of breech delivery except for those with hyperextensio...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(87)90193-1
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the effect of discordant fetal growth on subsequent perinatal and neonatal outcome for different degrees of birth weight discordance in preterm twin gestations. STUDY DESIGN:One hundred twenty-two live born twin sets delivered between 25 and 34 completed weeks' gest...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(95)90027-6
更新日期：1995-03-01 00:00:00
abstract：:Relationships among prepregnancy weight status, prenatal weight gain, and the outcome of 922 twin gestations delivered at term were retrospectively investigated with the use of data provided by linked birth-death certificates in Kansas, 1980 to 1986. Infant birth weights were found to increase linearly with prenatal w...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(90)90845-x
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVES:Our goals were (1) to determine whether hypertension, proteinuria, and glomerular endotheliosis can be produced by chronic reduction of lower aortic pressure in pregnant rhesus monkeys and (2) to study the time course of the development of hypertension by means of longitudinal arterial blood pressure measure...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(93)90171-e
更新日期：1993-07-01 00:00:00
abstract：:The presence of fetal breathing, even if episodic in character, may not indicate fetal well being. In a study of fetal lambs with long-term implantation of catheters and electrodes, five of six lambs which died before the onset of labor had terminal episodes of continuous breathing, preceded by 4 1/4 to 45 1/2 hours o...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(16)33138-6
更新日期：1978-08-15 00:00:00
abstract：OBJECTIVE:Several recent reports have demonstrated the expression of luteinizing hormone-releasing hormone receptors by human ovarian and endometrial cancers. Controversy persists on the relevance of this finding, in particular whether these receptors mediate direct antiproliferative effects of luteinizing hormone-rele...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2002.119633
更新日期：2002-02-01 00:00:00
