Reversibility of bronchospasm in airway obstruction.

Abstract:

:In a double-blind, randomized crossover study of 12 patients suffering from chronic bronchitis, the comparative influence of equipotent doses of pindolol (5 mg) and metoprolol (100 mg) on the bronchodilatory potential of inhaled fenoterol (0.4 mg), a beta 2-agonist, was investigated by means of body plethysmography. Neither beta-blocker caused bronchospasm or attenuated the bronchodilation due to fenoterol. The results are not pertinent to the potential risk of bronchospastic complications induced by beta 1-selective or nonselective drugs, but they rule out a therapy-oriented differentiation between pindolol and cardioselective agents as far as the potential response to the bronchodilating activity of inhaled sympathomimetics is concerned.

journal_name

Am Heart J

journal_title

American heart journal

authors

von Wichert P

doi

10.1016/0002-8703(82)90138-7

subject

Has Abstract

pub_date

1982-08-01 00:00:00

pages

446-50

issue

2 Pt 2

eissn

0002-8703

issn

1097-6744

pii

0002-8703(82)90138-7

journal_volume

104

pub_type

临床试验,杂志文章,随机对照试验
  • Open clinical studies at a referral center: chronic maintenance tocainide therapy in patients with recurrent sustained ventricular tachycardia refractory to conventional antiarrhythmic agents.

    abstract::Chronic maintenance tocainide therapy was effective in controlling symptomatic, recurrent ventricular tachycardia in 11 of 15 patients. Patients were selected for tocainide therapy on the basis of refractoriness to conventional antiarrhythmic agents and responsiveness to the intravenous administration of lidocaine. Si...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(80)90208-2

    authors: Maloney JD,Nissen RG,McColgan JM

    更新日期:1980-12-01 00:00:00

  • Maladie du Roger 1879: a new translation for the centenary.

    abstract::A new translation of Roger's description of the clinical and anatomical findings in uncomplicated small VSD is presented. Reappraisal of Roger's observations in the light of our present understanding confirms that only our attitudes change; diseases remain the same. ...

    journal_title:American heart journal

    pub_type: 传,历史文章,杂志文章

    doi:10.1016/0002-8703(79)90041-3

    authors: Allwork SP

    更新日期:1979-09-01 00:00:00

  • Right ventricular myocardial infarction with anterior wall left ventricular infarction: an autopsy study.

    abstract::Right ventricular myocardial infarction has been reported to occur exclusively in association with inferior left ventricular infarction. To determine the frequency of right ventricular myocardial infarction in association with anterior left ventricular myocardial infarction, all hearts with anterior myocardial infarct...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90004-4

    authors: Cabin HS,Clubb KS,Wackers FJ,Zaret BL

    更新日期:1987-01-01 00:00:00

  • Resting thallium-201 myocardial perfusion patterns in patients with severe left ventricular dysfunction: differences between patients with primary cardiomyopathy, chronic coronary artery disease, or acute myocardial infarction.

    abstract::This study examined the value of resting thallium-201 imaging in differentiating patients with primary cardiomyopathy from those with ischemic cardiomyopathy. There were 15 patients with primary cardiomyopathy (group I); 20 with chronic CAD (group II); and 25 with acute Q wave myocardial infarction (group III). All pa...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90113-4

    authors: Iskandrian AS,Hakki AH,Kane S

    更新日期:1986-04-01 00:00:00

  • Long-term outcomes of arrhythmia and distinct electrophysiological features in congenitally corrected transposition of the great arteries in an Asian cohort.

    abstract::Congenitally corrected transposition of the great arteries (ccTGA) is associated with various types of arrhythmia, including supraventricular tachycardia (SVT) and complete atrioventricular block (cAVB). Our study aims to characterize the arrhythmia burden, associated risk factors, arrhythmia mechanisms, and the long-...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2020.10.057

    authors: Tseng WC,Huang CN,Chiu SN,Lu CW,Wang JK,Lin MT,Chen CA,Wu MH

    更新日期:2021-01-01 00:00:00

  • Cardiac structure and function in fetuses of mothers infected with HIV: the prospective PCHIV multicenter study.

    abstract:BACKGROUND:This study was designed to determine if vertically transmitted HIV infection and maternal infection with HIV are associated with altered cardiovascular structure and function in utero. METHODS:Fetal echocardiography was performed in 173 fetuses of 169 HIV-infected mothers (mean gestational age, 33.0 weeks; ...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1067/mhj.2000.109645

    authors: Hornberger LK,Lipshultz SE,Easley KA,Colan SD,Schwartz M,Kaplan S,Starc TJ,Ayres NA,Lai WW,Moodie DS,Kasten-Sportes C,Sanders SP

    更新日期:2000-10-01 00:00:00

  • Importance of follow-up medical and surgical approaches to prevent reinfarction, reocclusion, and recurrent angina following intracoronary thrombolysis with streptokinase in acute myocardial infarction.

    abstract::Thirty-four patients with acute myocardial infarction (mean age 55 years) who received intracoronary streptokinase for coronary thrombosis were followed for a mean of 9.4 months (longest 25 months) following the procedure of percutaneous transluminal coronary recanalization (PTCR). Twelve patients had undergone corona...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(82)90265-4

    authors: Lee G,Low RI,Takeda P,Joe P,DeMaria AN,Amsterdam EA,Lui H,Dietrich P,Lee K,Mason DT

    更新日期:1982-10-01 00:00:00

  • Diagnostic value of 12-lead electrocardiogram during dobutamine echocardiographic studies.

    abstract:BACKGROUND:The diagnostic value of 12-lead electrocardiography during dobutamine stress echocardiography (DSE) is not well documented. METHODS AND RESULTS:We reviewed the records of 116 patients referred for DSE and coronary angiography, 52 of whom were excluded because of abnormal ST segment or inadequate DSE. Of the...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(98)70163-2

    authors: Shaheen J,Luria D,Klutstein MW,Rosenmann D,Tzivoni D

    更新日期:1998-12-01 00:00:00

  • A propensity analysis of the risk of vascular complications after cardiac catheterization procedures with the use of vascular closure devices.

    abstract:BACKGROUND:Complications of vascular access are one of the most common adverse events after coronary angiography and percutaneous coronary intervention (PCI) and are reported to occur in 1% to 9% of cases. There are conflicting reports of the association of vascular complications with the use of vascular closure device...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2006.12.014

    authors: Arora N,Matheny ME,Sepke C,Resnic FS

    更新日期:2007-04-01 00:00:00

  • Long-term efficacy of mexiletine alone and in combination with class Ia antiarrhythmic drugs for refractory ventricular arrhythmias.

    abstract::The efficacy of mexiletine used alone, and in combination with a class Ia antiarrhythmic drug, was assessed in 159 previously drug-refractory patients with ventricular tachycardia (VT) during serial electrophysiologic studies and during long-term (5-year) clinical follow-up. Electrically-inducible ventricular tachycar...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(88)90482-6

    authors: Whitford EG,McGovern B,Schoenfeld MH,Garan H,Newell JB,McElroy M,Ruskin JN

    更新日期:1988-02-01 00:00:00

  • Current role of sodium bicarbonate-based preprocedural hydration for the prevention of contrast-induced acute kidney injury: a meta-analysis.

    abstract:BACKGROUND:The optimal hydration strategy for prevention of contrast-induced acute kidney injury (AKI) remains unknown. The purpose of this meta-analysis is to compare the effectiveness of normal saline (NS) versus sodium bicarbonate hydration (NaHCO(3)) for prevention of contrast-induced AKI. METHODS:We performed a m...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.ahj.2008.05.014

    authors: Hogan SE,L'Allier P,Chetcuti S,Grossman PM,Nallamothu BK,Duvernoy C,Bates E,Moscucci M,Gurm HS

    更新日期:2008-09-01 00:00:00

  • Predictors of response to cardiac resynchronization therapy (PROSPECT)--study design.

    abstract:BACKGROUND:Cardiac resynchronization therapy (CRT) is currently indicated in patients with moderate to severe heart failure, a wide QRS complex and significant left ventricular dysfunction despite optimal medical therapy. Adoption of these criteria for CRT results in a favorable response in only two thirds of candidate...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2004.12.013

    authors: Yu CM,Abraham WT,Bax J,Chung E,Fedewa M,Ghio S,Leclercq C,León AR,Merlino J,Nihoyannopoulos P,Notabartolo D,Sun JP,Tavazzi L,PROSPECT Investigators.

    更新日期:2005-04-01 00:00:00

  • Combination of B-type natriuretic peptide and peak oxygen consumption improves risk stratification in outpatients with chronic heart failure.

    abstract:BACKGROUND:Peak oxygen consumption is a cornerstone for prognostic determination in patients with congestive heart failure. The purpose of this study was to assess whether plasma B-type natriuretic peptide (BNP) provided any additional prognostic information. METHODS:Plasma concentrations of atrial natriuretic peptide...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/S0002-8703(03)00365-X

    authors: Isnard R,Pousset F,Chafirovskaïa O,Carayon A,Hulot JS,Thomas D,Komajda M

    更新日期:2003-10-01 00:00:00

  • Randomized evaluation of short-term dual antiplatelet therapy in patients with acute coronary syndrome treated with the COMBO dual therapy stent: rationale and design of the REDUCE trial.

    abstract:BACKGROUND:The optimal duration of dual antiplatelet therapy (DAPT) in acute coronary syndrome (ACS) patients treated with drug eluting stents (DES) is still under debate. Recent meta-analyses on ≤6months versus 12months DAPT suggest that bleeding rates can be reduced, without a higher rate of thrombotic complications....

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2016.04.016

    authors: Camaro C,Damen SA,Brouwer MA,Kedhi E,Lee SW,Verdoia M,Barbieri L,Rognoni A,van T Hof AW,Ligtenberg E,de Boer MJ,Suryapranata H,De Luca G

    更新日期:2016-08-01 00:00:00

  • Glomerular capillary pressure and hypertension.

    abstract::In patients with essential hypertension, glomerular filtration rate remains normal or elevated, whereas renal blood flow tends to be lower, which results in an increased filtration fraction. The afferent (preglomerular) arteriolar resistance determines the fraction of the pressure that is transmitted to the glomerular...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/0002-8703(91)90945-e

    authors: Larochelle P

    更新日期:1991-10-01 00:00:00

  • The 6-minute walk test: how important is the learning effect?

    abstract:BACKGROUND:The 6-minute walk test is a submaximal exercise test that is widely used as an outcomes measure in clinical trials and cardiopulmonary rehabilitation. An initial learning effect with repeated administration is well documented, but it is unknown whether this learning effect persists with time. METHODS:This s...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/S0002-8703(03)00119-4

    authors: Wu G,Sanderson B,Bittner V

    更新日期:2003-07-01 00:00:00

  • In women with symptoms of cardiac ischemia, nonobstructive coronary arteries, and microvascular dysfunction, angiotensin-converting enzyme inhibition is associated with improved microvascular function: A double-blind randomized study from the National Hea

    abstract:BACKGROUND:We investigated the role of the renin-angiotensin system in women with signs and symptoms of ischemia without obstructive coronary artery disease (CAD). Although microvascular dysfunction has been suggested to explain this syndrome and recently was found to predict adverse outcomes, the mechanisms and treatm...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2011.07.011

    authors: Pauly DF,Johnson BD,Anderson RD,Handberg EM,Smith KM,Cooper-DeHoff RM,Sopko G,Sharaf BM,Kelsey SF,Merz CN,Pepine CJ

    更新日期:2011-10-01 00:00:00

  • Cardiac biomarker measurement after elective percutaneous coronary interventions in older patients: insights from the National Cardiovascular Data Registry.

    abstract:BACKGROUND:Guidelines recommend consideration of cardiac biomarker measurement after elective percutaneous coronary intervention (PCI), especially with complex cases or complicated procedures. However, the long-term prognostic implications of biomarker measurement after elective PCI have not been well characterized in ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2013.09.007

    authors: Wang TY,McCoy LA,Messenger JC,Neely ML,Ho KK,Roe MT,Anderson HV

    更新日期:2013-11-01 00:00:00

  • Sex differences in depression after coronary artery bypass graft surgery.

    abstract:BACKGROUND:Previous research suggests that after coronary artery bypass graft (CABG) surgery, women fare worse than men. This study investigates sex differences in depression during recovery from CABG surgery. METHODS:We followed 137 patients (72 men, 65 women) undergoing elective isolated first CABG surgery between J...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.05.005

    authors: Mitchell RH,Robertson E,Harvey PJ,Nolan R,Rodin G,Romans S,Abramson BL,Brister SJ,Ivanov J,Stewart DE

    更新日期:2005-11-01 00:00:00

  • Clinical correlates, heritability, and genetic linkage of circulating CD40 ligand in the Framingham Offspring Study.

    abstract:BACKGROUND:The CD40 receptor and its ligand (CD40L) are known to modulate both inflammation and thrombosis-2 processes important for the development and clinical expression of atherosclerosis. Circulating soluble CD40L (sCD40L) concentration predicts cardiovascular risk in selected patient samples. The purpose of this ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2008.06.041

    authors: Keaney JF Jr,Lipinska I,Larson MG,Dupuis J,Freedman JE,Hamburg NM,Massaro JM,Rong J,Sutherland P,Vita JA,Vasan RS,Benjamin EJ

    更新日期:2008-11-01 00:00:00

  • The effect of thromboxane inhibition on vulnerability to ventricular fibrillation in the acute and chronic feline infarction models.

    abstract::Inhibition of the enzyme that synthesizes thromboxanes may protect against the development of ventricular fibrillation (VF) during acute myocardial ischemia. This study was carried out to test this hypothesis with a new thromboxane synthetase inhibitor, and to extend the studies to alternative animal models of myocard...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90622-4

    authors: O'Connor KM,Friehling TD,Kowey PR

    更新日期:1989-04-01 00:00:00

  • Right-sided valvular endocarditis: etiology, diagnosis, and an approach to therapy.

    abstract::Right- and left-sided endocarditis are two distinct entities, both clinically and experimentally. As such, they require different clinical approaches. The accurate diagnosis of right-sided endocarditis rests largely on a high index of suspicion which is often raised in the case of an intravenous drug abuser with fever...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90564-8

    authors: Robbins MJ,Soeiro R,Frishman WH,Strom JA

    更新日期:1986-01-01 00:00:00

  • The role of preoperative coronary angiography in the setting of type A acute aortic dissection: insights from the International Registry of Acute Aortic Dissection.

    abstract:BACKGROUND:Performing preoperative coronary angiography (CA) before surgical repair of a type A acute aortic dissection (TA-AAD) remains controversial. Although the information provided by CA may be useful in planning the surgical approach, the potential delay to surgery and complications of CA may confer added risk of...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2011.01.010

    authors: Ramanath VS,Eagle KA,Nienaber CA,Isselbacher EM,Froehlich JB,Montgomery DG,Cooper JV,Gu X,Evangelista A,Voehringer M,Beckman J,Myrmel T,Pape L,Pyeritz RE,Hirsch AT,Gilon D,Bossone E

    更新日期:2011-04-01 00:00:00

  • Gender does not influence acute myocardial infarction in adult dogs.

    abstract::Mechanisms responsible for the well-documented "protection" against myocardial ischemia and infarction in young women and subsequent loss of protection after menopause remain speculative. One possibility is that gender-related variables (such as endogenous hormone levels or regular loss of stored iron) alter the susce...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(95)90390-9

    authors: Przyklenk K,Ovize M,Bauer B,Kloner RA

    更新日期:1995-06-01 00:00:00

  • PTCA following myocardial infarction: use of bailout fibrinolysis to improve results.

    abstract::The results of percutaneous transluminal coronary angioplasty (PTCA) in 307 lesions in 235 patients within 60 days of myocardial infarction (MI) were compared with the PTCA results in 591 lesions in 489 patients without recent MI, and the effect of fibrinolysis to treat recurring occlusive clot during angioplasty was ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(90)90065-6

    authors: Haft JI,Goldstein JE,Homoud MK,Aaronoff M

    更新日期:1990-08-01 00:00:00

  • Percutaneous alternative to the Maze procedure for the treatment of persistent or long-standing persistent atrial fibrillation (aMAZE trial): Rationale and design.

    abstract:BACKGROUND:Pulmonary vein antrum isolation (PVI) as a treatment of paroxysmal atrial fibrillation (AF) is associated with a high rate of success; however, outcomes for treating persistent and long-standing persistent AF with PVI alone are substantially lower and often require multiple procedures to maintain long-term f...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2015.09.019

    authors: Lee RJ,Lakkireddy D,Mittal S,Ellis C,Connor JT,Saville BR,Wilber D

    更新日期:2015-12-01 00:00:00

  • The role of transesophageal echocardiography in cardiac donor screening.

    abstract::Transthoracic echocardiography has played a useful role in the screening of cardiac transplant donors. However, transthoracic echocardiograms may be suboptimal in many patients on ventilators. The role of transesophageal echocardiography in cardiac donor screening is unknown. Therefore we compared the potential benefi...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(93)90758-2

    authors: Stoddard MF,Longaker RA

    更新日期:1993-06-01 00:00:00

  • Cangrelor reduces the risk of ischemic complications in patients with single-vessel and multi-vessel disease undergoing percutaneous coronary intervention: Insights from the CHAMPION PHOENIX trial.

    abstract:OBJECTIVE:To examine the safety and efficacy of cangrelor in patients with single-vessel disease (SVD) and multi-vessel disease (MVD). BACKGROUND:Cangrelor, an intravenous, rapidly acting P2Y12 inhibitor, is superior to clopidogrel in reducing ischemic events among patients receiving percutaneous coronary intervention...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2017.02.031

    authors: Abnousi F,Sundaram V,Yong CM,Prats J,Deliargyris EN,Stone GW,Hamm CW,Steg PG,Gibson CM,White HD,Price MJ,Généreux P,Desai M,Yang L,Ding VY,Harrington RA,Bhatt DL,Mahaffey KW

    更新日期:2017-06-01 00:00:00

  • Prognostic value of C-reactive protein and cardiac troponin I in primary percutaneous interventions for ST-elevation myocardial infarction.

    abstract:BACKGROUND:The rise in cardiac troponin I after ST-elevation myocardial infarction treated by primary percutaneous coronary interventions (PCIs) is predictive of infarct size and left ventricular ejection fraction (LVEF). However, the comparative value of C-reactive protein (CRP) and troponin I for infarct size evaluat...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2006.07.016

    authors: Ohlmann P,Jaquemin L,Morel O,El Behlgiti R,Faure A,Michotey MO,Beranger N,Roul G,Schneider F,Bareiss P,Monassier JP

    更新日期:2006-12-01 00:00:00

  • Segmental wall motion abnormalities in the absence of clinically documented myocardial infarction: clinical significance and evidence of hibernating myocardium.

    abstract::To determine the frequency and significance of left ventricular wall motion abnormalities in patients without clinical evidence of myocardial infarction, we reviewed the two-dimensional echocardiograms of 252 patients who had no history or electrocardiographic evidence of myocardial infarction and who subsequently und...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(91)90666-6

    authors: Lewis SJ,Sawada SG,Ryan T,Segar DS,Armstrong WF,Feigenbaum H

    更新日期:1991-04-01 00:00:00