Serum uric acid levels among thirty-four thousand people in Japan.

abstract：:Changes in cellular infiltrate and expression of cytokines, chemokines, and cell adhesion molecules as a result of therapeutic interventions in rheumatoid arthritis can be demonstrated in the synovial membrane. However, before synovial tissue analysis can be used as an outcome measure in such studies, standardisation ...

journal_title：Annals of the rheumatic diseases

authors： Smith MD,Baeten D,Ulfgren AK,McInnes IB,Fitzgerald O,Bresnihan B,Tak PP,Veale D,OMERACT synovial special interests group.

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:To compare the risk of keratinoctye skin cancer (basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)) in patients treated for rheumatoid arthritis (RA) compared with the general population, and to determine whether anti-tumour necrosis factor (TNF) therapy exacerbates this risk. METHODS:Patients wi...

journal_title：Annals of the rheumatic diseases

authors： Mercer LK,Green AC,Galloway JB,Davies R,Lunt M,Dixon WG,Watson KD,British Society for Rheumatology Biologics Register Control Centre Consortium.,Symmons DP,Hyrich KL,British Society for Rheumatology Biologics Register.

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:(1) To compare clinical outcome and symptomatology of rheumatoid cervical myelopathy between patients managed conservatively and surgically. (2) To determine if surgical outcome has improved since the series published from this unit in 1987. (3) To examine the role of magnetic resonance imaging (MRI) in the ...

journal_title：Annals of the rheumatic diseases

authors： Hamilton JD,Gordon MM,McInnes IB,Johnston RA,Madhok R,Capell HA

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To conduct a cross-sectional review of non-selected consecutive outpatients with rheumatoid arthritis (RA) as part of standard clinical care in 15 countries for an overview of the characteristics of patients with RA. METHODS:The review included current disease activity using data from clinical assessment and...

journal_title：Annals of the rheumatic diseases

authors： Sokka T,Kautiainen H,Toloza S,Mäkinen H,Verstappen SM,Lund Hetland M,Naranjo A,Baecklund E,Herborn G,Rau R,Cazzato M,Gossec L,Skakic V,Gogus F,Sierakowski S,Bresnihan B,Taylor P,McClinton C,Pincus T,QUEST-RA Group.

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To perform a prospective long term follow up study comparing conventional radiography (CR), ultrasonography (US), and magnetic resonance imaging (MRI) in the detection of bone erosions and synovitis in rheumatoid arthritis (RA) finger joints. METHODS:The metacarpophalangeal and proximal interphalangeal joint...

journal_title：Annals of the rheumatic diseases

authors： Scheel AK,Hermann KG,Ohrndorf S,Werner C,Schirmer C,Detert J,Bollow M,Hamm B,Müller GA,Burmester GR,Backhaus M

更新日期：2006-05-01 00:00:00

abstract：:Decreased immunoglobulin production in pokeweed mitogen driven lymphocyte cultures has been reported in rheumatoid arthritis (RA). Here various activators and experimental designs have been used to determine the contribution of B cells, T cells, or monocytes to this low response. Sixty patients with RA and paired cont...

journal_title：Annals of the rheumatic diseases

authors： Jokinen I,Poikonen K,Möttönen T,Hannonen P,Oka M,Ilonen J,Surcel HM,Karttunen R,Arvilommi H

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Antibodies targeting citrullinated antigens are specific for rheumatoid arthritis (RA). Citrullination is catalysed by the peptidylarginine deiminase (PAD) enzyme family. Critical enzymes are often targeted by disease-specific antibodies in complex immune-mediated diseases. Here, we have tested for autoantib...

journal_title：Annals of the rheumatic diseases

authors： Halvorsen EH,Pollmann S,Gilboe IM,van der Heijde D,Landewé R,Ødegård S,Kvien TK,Molberg Ø

更新日期：2008-03-01 00:00:00

abstract：:A method is described for evaluating the progress of patients with back pain. Various symptoms were scored on analogue scales and spinal motion was measured by various techniques. These data were integrated to make subjective and objective indices respectively. Reasonable reproducibility of the measurements was obtain...

journal_title：Annals of the rheumatic diseases

authors： Million R,Nilsen KH,Jayson MI,Baker RD

更新日期：1981-10-01 00:00:00

abstract：:227 patients with psoriasis and various forms of arthritis have been kept under review. Psoriasis and inflammatory arthropathy was present in 168 patients, of whom 94 have been followed up for more than 10 years. An arthritis indistinguishable from rheumatoid disease was present in 78%, distal joint arthritis in 16-6%...

journal_title：Annals of the rheumatic diseases

authors： Roberts ME,Wright V,Hill AG,Mehra AC

更新日期：1976-06-01 00:00:00

abstract：OBJECTIVE:To study the association between silica exposure, separately as well as combined with smoking, and the risk of developing rheumatoid arthritis (RA) with or without the presence of antibodies against citrullinated peptide antigens (ACPA). METHODS:This Swedish population based case-control study analysed 577 i...

journal_title：Annals of the rheumatic diseases

authors： Stolt P,Yahya A,Bengtsson C,Källberg H,Rönnelid J,Lundberg I,Klareskog L,Alfredsson L,EIRA Study Group.

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential utility of a dual energy CT (DECT) scan in assessing urate deposits among patients with tophaceous gout, and obtain computerised quantification of tophus volume in peripheral joints. METHODS:20 consecutive patients with tophaceous gout and 10 control patients with other arthritic co...

journal_title：Annals of the rheumatic diseases

authors： Choi HK,Al-Arfaj AM,Eftekhari A,Munk PL,Shojania K,Reid G,Nicolaou S

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To characterise activation of the type I interferon (IFN) pathway in patients with systemic lupus erythematosus (SLE), dermatomyositis (DM), polymyositis (PM), rheumatoid arthritis (RA) and systemic scleroderma (SSc) and to evaluate the potential to develop a molecular diagnostic tool from the peripheral bloo...

journal_title：Annals of the rheumatic diseases

authors： Higgs BW,Liu Z,White B,Zhu W,White WI,Morehouse C,Brohawn P,Kiener PA,Richman L,Fiorentino D,Greenberg SA,Jallal B,Yao Y

更新日期：2011-11-01 00:00:00

abstract：:The performance of four different assays for circulating immune complexes-the C1q solid phase method, one using protein A and one using anti-IgG, C1q PEG, and the 2% PEG method-were compared in 61 patients with early rheumatoid arthritis followed up for two years. There were weak but statistically significant correlat...

journal_title：Annals of the rheumatic diseases

authors： Reeback JS,Silman AJ,Holborow EJ,Maini RN,Hay FC

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVES:Few studies have addressed the natural course of, or prognostic factors for the salivary and lacrimal function in primary Sjögren syndrome (SS). Except for the early stages, glandular function has been seemingly stable, and SS A antigen (SSA) seropositivity and hypocomplementemia may predict a decline in the...

journal_title：Annals of the rheumatic diseases

authors： Haldorsen K,Moen K,Jacobsen H,Jonsson R,Brun JG

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To determine the incremental cost-effectiveness ratios (ICERs) of two therapeutic regimens of infliximab for ankylosing spondylitis (AS). METHODS:230 patients with active AS who were participating in a randomised controlled trial comparing two infliximab infusion modalities-every 6 weeks (Q6) and on demand (...

journal_title：Annals of the rheumatic diseases

authors： Fautrel B,Benhamou M,Breban M,Roy C,Lenoir C,Trape G,Baleydier A,Ravaud P,Dougados M

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:In juvenile idiopathic arthritis (JIA), the efficacy of very early disease-modifying drug therapy, synthetic or biological, is not well known. Three alternative strategies were compared for treating recent-onset polyarticular JIA. METHODS:In a 54-week multicentre open-label clinical trial, 60 disease-modify...

journal_title：Annals of the rheumatic diseases

authors： Tynjälä P,Vähäsalo P,Tarkiainen M,Kröger L,Aalto K,Malin M,Putto-Laurila A,Honkanen V,Lahdenne P

更新日期：2011-09-01 00:00:00

abstract：:Previous work has suggested that prior poor reproductive outcome may be a risk factor in rheumatoid arthritis (RA). A case-control study of 195 women with RA and 462 control women from two different sources is presented here. No increase in rates of spontaneous abortion was seen in the women with RA; indeed a protecti...

journal_title：Annals of the rheumatic diseases

authors： Spector TD,Silman AJ

更新日期：1990-01-01 00:00:00

abstract：:A previously normal 58-year-old woman developed a widespread psoriatic rash and asymmetrical peripheral polyarthritis a week after beginning treatment with oxprenolol for hypertension. Skin and joint disease resolved simultaneously after drug withdrawal and have not recurred. ...

journal_title：Annals of the rheumatic diseases

authors： Macfarlane DG,Settas L

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Patients with rheumatoid arthritis (RA) have an increased risk of certain solid cancers, in particular lung cancer, compared to the general population. Treatment with tumour necrosis factor (TNF) inhibitors (TNFi) may further enhance this risk. OBJECTIVES:To compare the risk of solid cancer in patients with...

journal_title：Annals of the rheumatic diseases

authors： Mercer LK,Lunt M,Low AL,Dixon WG,Watson KD,Symmons DP,Hyrich KL,BSRBR Control Centre Consortium.

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:To investigate the role of CD8 cell subsets in the pathogenesis of rheumatoid arthritis (RA) and the phenotypes of T cells adherent or non-adherent to the target cells (endothelial cells and synovial cells) pre-treated with IL-1 beta. METHODS:The expression of S6F1 on CD8 cells and that of an activation mark...

journal_title：Annals of the rheumatic diseases

authors： Ueki Y,Eguchi K,Miyake S,Nagataki S,Tominaga Y

更新日期：1994-12-01 00:00:00

abstract：:The effect of auranofin on human neutrophil (PMN) 5-lipoxygenase activity and leucotriene B4 (LTB4) chemotaxis was investigated. [1-14C]Arachidonic acid was incorporated into the purified cells until steady state conditions were obtained. After preincubations with serial dilutions of auranofin arachidonic acid release...

journal_title：Annals of the rheumatic diseases

authors： Elmgreen J,Ahnfelt-Rønne I,Nielsen OH

更新日期：1989-02-01 00:00:00

abstract：QUESTION:Which is the best strategy to achieve (drug-free) inactive disease in juvenile idiopathic arthritis (JIA)? METHODS:In a randomised, single-blinded, study in disease-modifying anti-rheumatic drug (DMARD)-naive patients with JIA, three treatment-strategies were compared: (1) sequential DMARD-monotherapy (sulfas...

journal_title：Annals of the rheumatic diseases

authors： Hissink Muller P,Brinkman DMC,Schonenberg-Meinema D,van den Bosch WB,Koopman-Keemink Y,Brederije ICJ,Bekkering PW,Kuijpers TW,Van Rossum M,van Suijlekom-Smit LWA,van den Berg JM,Boehringer S,Allaart CF,Ten Cate R

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:The humoral immune response against a broad spectrum of cartilage antigens (cellular and matrix antigens) was studied in a group of patients who showed resorption and/or rejection of transplanted cartilage in nasal surgery. METHODS:Sera were obtained from patients with successful and unsuccessful cartilage ...

journal_title：Annals of the rheumatic diseases

authors： Bujia J,Alsalameh S,Naumann A,Wilmes E,Sittinger M,Burmester GR

更新日期：1994-04-01 00:00:00

abstract：:A patient with Portuguese familial amyloid polyneuropathy who developed haemarthroses secondary to pathological fractures is described. Amyloid material was demonstrated on bone biopsy and confirmed immunohistochemically to be transthyretin (prealbumin). Although amyloid deposits in bone have been described in other t...

journal_title：Annals of the rheumatic diseases

authors： Allard SA,King RH,Thomas PK,Bourke BE

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVE:To carry out a prospective two year follow up study comparing conventional radiography, three-phase bone scintigraphy, ultrasonography (US), and three dimensional (3D) magnetic resonance imaging (MRI) with precontrast and dynamic postcontrast examination in detecting early arthritis. The aim of the follow up ...

journal_title：Annals of the rheumatic diseases

authors： Backhaus M,Burmester GR,Sandrock D,Loreck D,Hess D,Scholz A,Blind S,Hamm B,Bollow M

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the contribution of polymorphisms in the vitamin D receptor (VDR) gene to ethnic variations in bone mass in mother and children from different ethnic origins. METHODS:VDR genotypes and bone mass in 43 African-American and white women, mean age 38.2 years, and 41 of their children were studied. Al...

journal_title：Annals of the rheumatic diseases

authors： Nelson DA,Vande Vord PJ,Wooley PH

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To elaborate a clinical practice decision tree for the choice of the first disease modifying antirheumatic drug (DMARD) for untreated rheumatoid arthritis of less than six months' duration. METHODS:Four steps were employed: (1) review of published reports on DMARD efficacy against rheumatoid arthritis; (2) i...

journal_title：Annals of the rheumatic diseases

authors： Le Loët X,Berthelot JM,Cantagrel A,Combe B,De Bandt M,Fautrel B,Flipo RM,Lioté F,Maillefert JF,Meyer O,Saraux A,Wendling D,Guillemin F

更新日期：2006-01-01 00:00:00

abstract：:A 49 year old man is described with a polyarticular arthritis. Synovial fluid aspirated from the knee joint showed monosodium urate monohydrate and calcium pyrophosphate dihydrate by polarised light microscopy. Additionally, diphosphonate binding and scanning electron microscopy with energy dispersive analysis showed ...

journal_title：Annals of the rheumatic diseases

authors： Halverson PB,Ryan LM

更新日期：1988-10-01 00:00:00

abstract：:The first biological therapeutics in rheumatology are approaching patent expiration, encouraging development of 'follow-on' versions, known as 'biosimilars'. Biological agents range from simple replacement hormones to complex monoclonal antibodies and soluble receptors: large, intricate proteins with unique tertiary a...

journal_title：Annals of the rheumatic diseases

authors： Dörner T,Strand V,Castañeda-Hernández G,Ferraccioli G,Isaacs JD,Kvien TK,Martin-Mola E,Mittendorf T,Smolen JS,Burmester GR

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:Chondrocytic matrix metalloproteinases (MMPs) are believed to be important in osteoarthritic cartilage degradation. The cartilage lesion of osteoarthritis (OA) is focal and often progressive. During its development chondrocytes differentially up and down regulate production of mRNA for individual MMPs. This ...

journal_title：Annals of the rheumatic diseases

authors： Freemont AJ,Byers RJ,Taiwo YO,Hoyland JA

更新日期：1999-06-01 00:00:00