The production of bacteriocin-like substances by the oral bacterium Streptococcus salivarius.

Abstract:

:Inhibitory substances produced by six strains of Streptococcus salivarius were isolated and partially characterized. The six prototype producer strains were selected initially on the basis of their differing spectra of inhibitory activity when tested against a set of nine standard indicator strains. Optimal production conditions were defined for each producer strain and inhibitor-containing extracts were obtained for characterization studies. All of the inhibitors appeared to be proteinaceous substances of molecular weight greater than 3500. When tested against a Streptococcus pyogenes indicator strain, one of the inhibitors was bactericidal, but the other five appeared to be bacteriostatic. Some differences between the inhibitors were observed with respect to heat and enzyme sensitivities.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Dempster RP,Tagg JR

doi

10.1016/0003-9969(82)90136-4

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

151-7

issue

2

eissn

0003-9969

issn

1879-1506

journal_volume

27

pub_type

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